metyrapone has been researched along with Electrolytes in 10 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Electrolytes: Substances that dissociate into two or more ions, to some extent, in water. Solutions of electrolytes thus conduct an electric current and can be decomposed by it (ELECTROLYSIS). (Grant & Hackh's Chemical Dictionary, 5th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of 5 to 9 days of metyrapone administration (400 mg/m2 every 4 h) on aldosterone, deoxycorticosterone, plasma renin activity, electrolyte balance, and blood pressure was investigated in 2 normotensive siblings (one of whom showed limited ACTH reserve), in 3 patients with hypertension and dexamethasone-suppressible hyperaldosteronism, and in a hypertensive patient with primary hyperaldosteronism due to bilateral adrenal hyperplasia." | 7.66 | Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism. ( Levine, LS; New, MI; Sonino, N, 1981) |
| "The effect of 5 to 9 days of metyrapone administration (400 mg/m2 every 4 h) on aldosterone, deoxycorticosterone, plasma renin activity, electrolyte balance, and blood pressure was investigated in 2 normotensive siblings (one of whom showed limited ACTH reserve), in 3 patients with hypertension and dexamethasone-suppressible hyperaldosteronism, and in a hypertensive patient with primary hyperaldosteronism due to bilateral adrenal hyperplasia." | 3.66 | Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism. ( Levine, LS; New, MI; Sonino, N, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SANCHEZ AGESTA, A | 1 |
| DURAN CARA, E | 1 |
| MORA LARA, RJ | 1 |
| PELAEZ REDONDO, J | 1 |
| SHICHINOHE, M | 1 |
| BONINI, A | 1 |
| TENZE, L | 1 |
| MAY, CD | 1 |
| RAPP, JP | 1 |
| MARTINI, O | 1 |
| VOIGT, KD | 1 |
| TAMM, J | 1 |
| DOELLE, W | 1 |
| Sonino, N | 1 |
| Levine, LS | 1 |
| New, MI | 1 |
| Kelly, WF | 1 |
| Barnes, AJ | 1 |
| Cassar, J | 1 |
| White, M | 1 |
| Mashiter, K | 1 |
| Loizou, S | 1 |
| Welbourn, RB | 1 |
| Joplin, GF | 1 |
| Voth, D | 1 |
| Kohlhardt, M | 1 |
| Nakazawa, S | 1 |
| Ueki, K | 1 |
10 other studies available for metyrapone and Electrolytes
| Article | Year |
|---|---|
[The effect of metopirone (Su-4885) on the urinary elimination of electrolytes].
Topics: Adrenal Cortex Function Tests; Electrolytes; Ketones; Metyrapone; Mineralocorticoid Receptor Antagon | 1963 |
[ACTION OF G-STROPHANTHIN ON WATER AND ELECTROLYTE METABOLISM IN CATS AND THE EFFECT OF ADRENOCORTICAL HORMONES ON THIS ACTION].
Topics: Adrenalectomy; Cats; Desoxycorticosterone; Diuresis; Electrolytes; Ions; Ketones; Metabolism; Metyra | 1963 |
[METOPIRONE IN LIVER CIRRHOSIS: DIURETIC AND ELECTROLYTIC CHANGES].
Topics: Diuresis; Diuretics; Electrolytes; Ketones; Liver Cirrhosis; Metyrapone; Mineralocorticoid Receptor | 1963 |
ELECTROLYTE EXCRETION BY SWEAT GLANDS AND KIDNEYS DURING SUPPRESSION OF ADRENAL CORTICOSTEROID ACTIVITY BY METHOPYRAPONE AND SPIRONOLACTONE.
Topics: Adrenal Cortex Hormones; Biomedical Research; Body Fluids; Chlorides; Dexamethasone; Electrolytes; I | 1965 |
EFFECT OF AN ALDOSTERONE ANTAGONIST ON ELECTROLYTES AND JUXTAGLOMERULAR GRANULARITY IN ADRENAL REGENERATION HYPERTENSION.
Topics: Adrenal Glands; Angiotensins; Blood; Blood Pressure; Electrolytes; Hypertension; Juxtaglomerular App | 1964 |
THE EFFECT OF A SALT LOAD AND ALDOSTERONE ON THE ACID-BASE-EQUILIBRIUM AND ON THE ELECTROLYTES IN BLOOD AND URINE OF NORMAL SUBJECTS FOLLOWING CHEMICAL BLOCKADE OF THE ADRENAL CORTEX.
Topics: Acid-Base Equilibrium; Adrenal Cortex; Aldosterone; Alkalosis; Biomedical Research; Blood; Body Flui | 1964 |
Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism.
Topics: Aldosterone; Child; Desoxycorticosterone; Electrolytes; Female; Humans; Hyperaldosteronism; Hyperten | 1981 |
Cushing's syndrome due to adrenocortical carcinoma - a comphrensive clinical and biochemical study of patients treated by surgery and chemotherapy.
Topics: 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Carcinoma; Cort | 1979 |
[Studies on the functional position of the zona glomerulosa in the adrenal cortex during the blockade of 18-hydroxylation with SU 5482].
Topics: Adrenal Glands; Aldosterone; Angiotensin II; Animals; Corticosterone; Electrolytes; Histocytochemist | 1967 |
[Endocrine, water and electrolyte abnormalities of craniopharyngioma (author's transl)].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; | 1974 |