metyrapone has been researched along with Edema, Pulmonary in 3 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the process of developing a model of Escherichia coli endotoxin-induced acute lung injury and shock in specific pathogen-free pigs, the effects of pretreatment with metyrapone (a cortisol-synthesis inhibitor) were examined." | 3.70 | Effect of cortisol-synthesis inhibition on endotoxin-induced porcine acute lung injury, shock, and nitric oxide production. ( Alving, K; Bergman, D; Middelveld, RJ; Wanecek, M; Weitzberg, E, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arimura, A | 1 |
| Asanuma, F | 1 |
| Yagi, H | 1 |
| Kurosawa, A | 1 |
| Harada, M | 1 |
| Andersson, SE | 1 |
| Källström, L | 1 |
| Malm, M | 1 |
| Miller-Larsson, A | 1 |
| Axelsson, B | 1 |
| Middelveld, RJ | 1 |
| Wanecek, M | 1 |
| Bergman, D | 1 |
| Weitzberg, E | 1 |
| Alving, K | 1 |
3 other studies available for metyrapone and Edema, Pulmonary
| Article | Year |
|---|---|
Involvement of thromboxane A2 in bronchial hyperresponsiveness but not lung inflammation induced by bacterial lipopolysaccharide in guinea pigs.
Topics: Animals; Bridged Bicyclo Compounds; Bronchial Hyperreactivity; Cytokines; Fatty Acids, Monounsaturat | 1993 |
Inhibition of nitric oxide synthase reduces Sephadex-induced oedema formation in the rat lung: dependence on intact adrenal function.
Topics: Adrenal Glands; Adrenalectomy; Animals; Arginine; Body Weight; Corticosterone; Dextrans; Enzyme Inhi | 1995 |
Effect of cortisol-synthesis inhibition on endotoxin-induced porcine acute lung injury, shock, and nitric oxide production.
Topics: Acid-Base Imbalance; Animals; Blood Gas Analysis; Bronchoalveolar Lavage Fluid; Disease Models, Anim | 1999 |