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metyrapone and Dwarfism, Pituitary

metyrapone has been researched along with Dwarfism, Pituitary in 28 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Dwarfism, Pituitary: A form of dwarfism caused by complete or partial GROWTH HORMONE deficiency, resulting from either the lack of GROWTH HORMONE-RELEASING FACTOR from the HYPOTHALAMUS or from the mutations in the growth hormone gene (GH1) in the PITUITARY GLAND. It is also known as Type I pituitary dwarfism. Human hypophysial dwarf is caused by a deficiency of HUMAN GROWTH HORMONE during development.

Research Excerpts

ExcerptRelevanceReference
" In 4 cases in Group II, the plasma cortisol level increased 120 min after the infusion of lysine-vasopressin, whereas oral administration of metyrapone and hypoglycemia induced by insulin did not increase the plasma cortisol levels."3.66Hypothalamic-pituitary functions in patients with idiopathic pituitary dwarfism. Further evidence for hypophysiotropic human deficiencies. ( Harada, T; Iida, Y; Kai, H; Miyai, K; Nose, O; Okada, S; Yabuuchi, H, 1978)
" Responses of LH and FSH to LH-RH improved markedly after a long term administration of LH-RH for a period of one month in 2 patients with gonadotropin deficiency."1.25Hypothalamic-pituitary functions in patients with idiopathic pituitary dwarfism. ( Demura, H; Demura, R; Jujo, K; Maeda, T; Odagiri, E; Shizume, K; Suda, T; Takano, K, 1975)

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-199028 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
RODRIGUEZDORESTE, OL1
MAS, S1
FERRARI, E1
PIOTTI, LE1
BOSCHERINI, B1
FISCHETTI, M1
SOYKA, LF1
ZISKIND, A1
CRAWFORD, JD1
AARSKOG, D1
BLIZZARD, RM1
MIGEON, CJ1
Rosenfield, RL1
Root, AW1
Bongiovanni, AM1
Eberlein, WR1
Matsumoto, I1
Lombardi, G1
Minozzi, M1
Faggiano, M1
Carella, C1
Jaquet, P1
Carayon, P1
Oliver, C1
Nose, O1
Iida, Y1
Kai, H1
Harada, T1
Okada, S1
Yabuuchi, H1
Miyai, K1
Demura, R1
Jujo, K1
Takano, K1
Odagiri, E1
Maeda, T1
Suda, T1
Demura, H1
Shizume, K1
Ginalska-Malinowska, M1
Małunowicz, E1
Romer, TE1
Filipek, M1
Werner, E1
Helge, H1
Igarashi, Y1
Joss, E1
Rossi, E1
Zahnd, G1
Zuppinger, K1
Krese, A1
Galvánek, M1
Kiselá, J1
Uhrín, P1
Kiselý, S1
Fasko, A1
Zurbrügg, RP2
Joss, EE2
Nishida, S1
Nakajima, T1
Harada, Y2
Okada, Y2
Hikita, T2
Ninomiya, T1
Ishihara, Y1
Ishitobi, K1
Esteban, BM1
Sheikholislam, BM1
Stempfel, RS1
Pichler, E1
Rath, F3
Siegel, R1
Waldhäusl, W2
Knorr, D1
Butenandt, O1
Tada, T1
Waldäusl, W1
Seip, M1
Trygstad, O1

Reviews

3 reviews available for metyrapone and Dwarfism, Pituitary

ArticleYear
[METHODOLOGICAL DATA ON THE DYNAMIC EVALUATION OF THE DIENCEPHALON-ANTERIOR PITUITARY-ADRENAL CORTEX SYSTEM].
    Archivio per le scienze mediche, 1964, Volume: 117

    Topics: Acromegaly; Addison Disease; Adrenal Cortex; Adrenocorticotropic Hormone; Cushing Syndrome; Dexameth

1964
[Short stature and growth hormone].
    Horumon to rinsho. Clinical endocrinology, 1972, Volume: 20, Issue:4

    Topics: Adolescent; Adult; Arginine; Birth Weight; Body Height; Child; Dwarfism; Dwarfism, Pituitary; Female

1972
[Hypophyseal dwarfism].
    Revista clinica espanola, 1969, Oct-15, Volume: 115, Issue:1

    Topics: Circadian Rhythm; Diagnosis, Differential; Dwarfism, Pituitary; Feedback; Growth Hormone; Humans; In

1969

Other Studies

25 other studies available for metyrapone and Dwarfism, Pituitary

ArticleYear
[STUDY OF PITUITARY FUNCTION WITH THE NEW METHOPYRAPONE TEST].
    Revista clinica espanola, 1963, Nov-15, Volume: 91

    Topics: Achondroplasia; Adolescent; Adrenal Cortex Hormones; Craniopharyngioma; Diagnosis, Differential; Dwa

1963
[THE METOPIRONE TEST IN THE DIFFERENTIAL DIAGNOSIS OF VARIOUS ENDOCRINE DISORDERS OF CHILDHOOD].
    Rivista di clinica pediatrica, 1963, Volume: 72

    Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Carbohydrate Metabolism; Child; Cu

1963
TREATMENT OF SHORT STATURE IN CHILDREN AND ADOLESCENTS WITH HUMAN PITUITARY GROWTH HORMONE (RABEN).
    The New England journal of medicine, 1964, Oct-08, Volume: 271

    Topics: Adolescent; Bone Development; Child; Cortisone; Dwarfism; Dwarfism, Pituitary; Growth; Growth Hormon

1964
RESPONSE TO METHOPYRAPONE (SU-4885) AND PYROGEN TEST IN IDIOPATHIC HYPOPITUITARY DWARFISM.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: 17-Hydroxycorticosteroids; Adolescent; Blood; Child; Dwarfism; Dwarfism, Pituitary; Hypopituitarism;

1965
Idiopathic anterior hypopituitarism in one of monozygous twins.
    The Journal of pediatrics, 1967, Volume: 70, Issue:1

    Topics: Adolescent; Diseases in Twins; Dwarfism, Pituitary; Female; Gonadotropins; Humans; Karyotyping; Mety

1967
[Clinical study of pituitary dwarfism].
    Nihon Shonika Gakkai zasshi. Acta paediatrica Japonica, 1967, Feb-01, Volume: 71, Issue:2

    Topics: Adolescent; Adult; Anabolic Agents; Child; Child, Preschool; Dwarfism, Pituitary; Female; Humans; Ma

1967
Plasma immunoreactive T3, TSH and ACTH before and after provocative tests in idiopathic hypopituitary dwarfism.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:1

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Child; Dwarfism, Pituitary; Female; Growth Hormone;

1975
Hypothalamic-pituitary functions in patients with idiopathic pituitary dwarfism. Further evidence for hypophysiotropic human deficiencies.
    European journal of pediatrics, 1978, Aug-17, Volume: 129, Issue:1

    Topics: Adolescent; Child; Dwarfism, Pituitary; Female; Gonadotropins; Growth Hormone; Humans; Hydrocortison

1978
Hypothalamic-pituitary functions in patients with idiopathic pituitary dwarfism.
    Endocrinologia japonica, 1975, Volume: 22, Issue:2

    Topics: Adolescent; Adult; Arginine; Child; Cortodoxone; Dwarfism, Pituitary; Follicle Stimulating Hormone;

1975
The metyrapone test in pituitary dwarfs--the determination of serum cortisol and 11-deoxycortisol by high-performance liquid chromatography.
    Endokrynologia Polska, 1987, Volume: 38, Issue:1

    Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Child; Child, Preschool; Chromatography, Hig

1987
[The human growth hormone. Clinical importance].
    Monatsschrift fur Kinderheilkunde, 1967, Volume: 115, Issue:4

    Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Blood Glucose; Child; Child, Preschool; Diagnosis, D

1967
[Studies on the pituitary ACTH secretory capacity in children using 11-beta-hydroxylase inhibitor (Metopirone). 2. Diagnostic value in pituitary dwarfism in children].
    Nihon Naibunpi Gakkai zasshi, 1966, Jan-20, Volume: 41, Issue:10

    Topics: 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Child; Child, Preschool; Dwarfism;

1966
[Biological diagnosis of pituitary nanism].
    Minerva pediatrica, 1966, Oct-13, Volume: 18, Issue:30

    Topics: Adrenocorticotropic Hormone; Blood Urea Nitrogen; Child; Child, Preschool; Dwarfism, Pituitary; Fema

1966
[Excretion of individual steroid in various forms of hypocorticism].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1967, Mar-01, Volume: 22, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adolescent; Adrenocorticotropic Hormone

1967
Diagnostic procedures in hypopituitary dwarfism. II. Evaluation of ACTH deficiency: metopirone test, the daily oscillation of plasma cortisol and its response to exogenous ACTH, lysin-vasopressin, insulin-induced hypoglycemia and general anesthesia.
    Helvetica paediatrica acta, 1970, Volume: 25, Issue:4

    Topics: Adolescent; Adrenocorticotropic Hormone; Anesthesia, General; Birth Injuries; Central Nervous System

1970
[Pituitary function test using synthetic lysine-8-vasopressin--comparison with metopirone test and insulin stress test].
    Naika. Internal medicine, 1971, Volume: 28, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anorexia Nervosa; Craniopharyngioma; Cushing S

1971
[Value of diagnostic tests in pituitary dwarfism. 2. ACTH secretion].
    Schweizerische medizinische Wochenschrift, 1969, Jul-26, Volume: 99, Issue:31

    Topics: Adrenocorticotropic Hormone; Child; Dwarfism, Pituitary; Growth Hormone; Humans; Metyrapone; Radioim

1969
Comparison of growth acceleration of pituitary dwarfs treated with anabolic steroid and thyroid hormone with normal growth spurt.
    Acta endocrinologica, 1973, Volume: 74, Issue:2

    Topics: Adolescent; Adult; Age Determination by Skeleton; Body Height; Body Weight; Child; Dwarfism, Pituita

1973
Hereditary isolated somatotropin deficiency: effects of human growth hormone administration.
    Pediatrics, 1972, Volume: 49, Issue:3

    Topics: Adolescent; Adrenal Cortex Hormones; Child; Dwarfism, Pituitary; Glucose; Glucose Tolerance Test; Go

1972
[Deficient plasma steroid increase following insulin administration in pituitary dwarfism. Therapeutic sequelae].
    Wiener klinische Wochenschrift, 1972, Sep-01, Volume: 84, Issue:85

    Topics: 17-Hydroxycorticosteroids; Adolescent; Child; Child, Preschool; Dwarfism; Dwarfism, Pituitary; Femal

1972
[Experiences with the prader nitrogen retention test with human pituitary growth hormone (HGH) in various types of dwarism].
    Monatsschrift fur Kinderheilkunde, 1967, Volume: 115, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adolescent; Blood Glucose; Child; Child, Preschool; Diagnosis, Differenti

1967
[Clinical studies on urinary 17-ketogenic steroid fractions. 3. SU-4885 test in normal subjects and the patients with various endocrine disorders].
    Nihon Naibunpi Gakkai zasshi, 1968, Mar-20, Volume: 43, Issue:12

    Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland N

1968
[On the management of hypophyseal-hypothalamic dwarfism using human growth hormone].
    Wiener klinische Wochenschrift, 1968, May-03, Volume: 80, Issue:18

    Topics: Child; Craniocerebral Trauma; Dwarfism, Pituitary; Enzyme Repression; Female; Growth Hormone; Humans

1968
[Studies on the demonstration of pituitary dwarfism].
    Helvetica paediatrica acta, 1969, Volume: 24, Issue:3

    Topics: Adolescent; Blood Glucose; Child; Child, Preschool; Diagnosis, Differential; Dwarfism, Pituitary; Fe

1969
Experiences with human growth hormone in pituitary dwarfism.
    Acta paediatrica Scandinavica, 1966, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Child; Dwarfism, Pituitary; Female; Glucose Tolerance Test; Gonadotropins, Pituit

1966