metyrapone has been researched along with Diseases of Endocrine System in 25 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cushing's syndrome is an uncommon disorder, but one that often presents diagnostic challenges to the managing physician." | 2.42 | Dynamic tests in the diagnosis and differential diagnosis of Cushing's syndrome. ( Grossman, AB; Morris, DG, 2003) |
| "Metyrapone test was found to produce a 223% increase in delta 4 levels, a 196% increase in DHA levels, and a decrease of more than 90% in the 11 beta OH delta 4 levels." | 1.26 | Simultaneous radioimmunoassay of androstenedione, dehydroepiandrosterone and 11-beta-hydroxyandrostenedione in plasma. ( Brerault, JL; Cathelineau, G; Dreux, C; Fiet, J; Gourmel, B; Julien, R; Villette, JM, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 24 (96.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KOREF, O | 1 |
| FEHER, T | 1 |
| JUVANCZ, I | 1 |
| FOELDES, J | 1 |
| FISCHER, J | 1 |
| BRUN, J | 1 |
| REVOL, A | 1 |
| PERRIN-FAYOLLE, M | 1 |
| DOLECEK, R | 1 |
| HERZIG, P | 1 |
| STOLBACH, L | 1 |
| EPPES, RB | 1 |
| STOCKDALE, F | 1 |
| MEHLER, R | 1 |
| WIELAND, RG | 1 |
| Morris, DG | 1 |
| Grossman, AB | 1 |
| Fiet, J | 1 |
| Gourmel, B | 1 |
| Villette, JM | 1 |
| Brerault, JL | 1 |
| Julien, R | 1 |
| Cathelineau, G | 1 |
| Dreux, C | 1 |
| Girard, J | 1 |
| Leisti, S | 1 |
| Giacovazzo, M | 1 |
| Görpe, A | 1 |
| Cakirgöz, C | 1 |
| Nagano, T | 1 |
| Sturm, A | 1 |
| Tucci, JR | 1 |
| Espiner, EA | 1 |
| Jagger, PI | 1 |
| Lauler, DP | 1 |
| Thorn, GW | 1 |
| Weber, A | 1 |
| Gossmann, HH | 1 |
| Cash, R | 1 |
| Petrini, MA | 1 |
| Brough, AJ | 1 |
| Shibata, I | 1 |
| Yazawa, T | 1 |
| Metcalf, MG | 1 |
| Drafta, D | 1 |
| Ciocîrdia, C | 1 |
| Stroe, E | 1 |
| Tache, A | 1 |
| Cristoveanu, A | 1 |
| Bunea, M | 1 |
| Bruton, J | 1 |
| Li, TK | 1 |
| Smith, GD | 1 |
| Torikai, T | 1 |
| Klimek, R | 1 |
| Paradysz, A | 1 |
| Guillemant, S | 1 |
| Thomopoulos, P | 1 |
| de Gennes, JL | 1 |
| Malmejac, A | 1 |
| Desgrez, P | 1 |
| Tada, T | 1 |
| Horster, FA | 1 |
2 reviews available for metyrapone and Diseases of Endocrine System
| Article | Year |
|---|---|
Dynamic tests in the diagnosis and differential diagnosis of Cushing's syndrome.
Topics: Adrenal Cortex Function Tests; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethasone; Dia | 2003 |
[Aspect of hormones and hypertension].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Catechol | 1969 |
23 other studies available for metyrapone and Diseases of Endocrine System
| Article | Year |
|---|---|
DETERMINATION OF URINARY 17-OH--CORTICOSTEROIDS BY A MODIFIED REDDY METHOD.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Chemist | 1964 |
[BESNIER-BOECK-SCHAUMANN SARCOIDOSIS AND INITIAL NEUROHYPOPHYSIAL HYPERREACTIVITY: PRACTICAL AND ETIOPATHOGENETIC VALUE OF THE METOPIRONE TEST].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Drug Therapy; Endocrine System Diseases; Hypot | 1964 |
[METOPIRON TESTS IN CLINICAL MEDICINE].
Topics: Clinical Medicine; Endocrine System Diseases; Metyrapone; Mineralocorticoid Receptor Antagonists | 1965 |
HYPOPITUITARISM PRESENTING AS HYPOADRENOTROPISM. A DISCUSSION OF TWO INTERESTING CASES.
Topics: Diagnosis, Differential; Endocrine System Diseases; Humans; Hypopituitarism; Metyrapone; Pituitary G | 1965 |
Simultaneous radioimmunoassay of androstenedione, dehydroepiandrosterone and 11-beta-hydroxyandrostenedione in plasma.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Androstenedione; Animals; Child; Child, Preschool; Circadi | 1980 |
[Radioimmunological measurement methods in ambulatory endocrinology].
Topics: Adrenocorticotropic Hormone; Dexamethasone; Endocrine System Diseases; Half-Life; Hormones; Humans; | 1976 |
Evaluation of 3 hour metyrapone test in children and adolescents.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Blood Glucose; Child; Child, Preschool; Cortodoxone; | 1977 |
[Treatment of rheumatoid arthritis].
Topics: Adrenal Glands; Adrenal Insufficiency; Anti-Bacterial Agents; Anti-Inflammatory Agents; Antimalarial | 1975 |
[Determination of ACTH reserve in endocrinologic and cirrhotic patients by the metopirone test].
Topics: Adrenocorticotropic Hormone; Endocrine System Diseases; Humans; Liver Cirrhosis; Metyrapone | 1965 |
[Urinary excretion of pregnanetriol in various internal diseases].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenalecto | 1966 |
[Progress in the clinical pathology of the adrenal cortex].
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Child; Cushing Synd | 1967 |
Vasopressin in the evaluation of pituitary-adrenal function.
Topics: Acromegaly; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Anorex | 1968 |
[Endoccinological changes as a result of obesity in juveniles].
Topics: Adolescent; Adrenocorticotropic Hormone; Age Factors; Blood Glucose; Body Height; Body Weight; Cushi | 1968 |
Ovarian dysfunction associated with an anticonvulsant drug.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Amin | 1969 |
[Urinary 17-hydroxycorticosteroid fractions].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Chemical Phenomena; Chemi | 1969 |
[Clinical studies of urinary 17-OHCS fraction in children. 2. ACTH test and metopirone test in healthy children and children with endocrinological diseases].
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Child; Child, Preschool; Endocrine System Di | 1970 |
Rapid gas chromatographic assays for androsterone and etiocholanolone in urine.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Amenorrhea; Androsterone; Chromatography, Gas; Dexam | 1970 |
[Urinary steroids under the effect of standardized dynamic tests].
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotropin; Cryptorchidism; | 1972 |
Comparison of results by four different procedures for determination of 17-hydroxycorticosteroids.
Topics: 17-Hydroxycorticosteroids; Binding, Competitive; Blood Proteins; Colorimetry; Endocrine System Disea | 1973 |
[Comparison of the results of metyrapone and water-salt tests in cases of neuroendocrinological disorders].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Endocrine System Diseases; Female; Humans; Hypoth | 1970 |
Determination of II-deoxycortisol by competitive protein binding.
Topics: 17-Hydroxycorticosteroids; Binding Sites; Endocrine System Diseases; Humans; Hydrocortisone; Metyrap | 1970 |
[Clinical studies on urinary 17-ketogenic steroid fractions. 3. SU-4885 test in normal subjects and the patients with various endocrine disorders].
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland N | 1968 |
[Anterior pituitary lobe activity and demonstration of an exophthalmos producing factor (EPF) in serum].
Topics: Cushing Syndrome; Endocrine System Diseases; Exophthalmos; Humans; Metyrapone; Pituitary Gland; Thyr | 1965 |