metyrapone has been researched along with Disease Exacerbation in 3 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Since hypercortisolism due to active Cushing's disease may worsen a COVID-19 infection, multi-disciplinary management that includes appropriate and prompt treatment strategies is mandatory in such cases." | 1.62 | Successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia. ( Atsumi, T; Cho, KY; Inoshita, N; Kamada, K; Kameda, H; Kenmotsu, Y; Konno, S; Miyoshi, H; Nakakubo, S; Nakamura, A; Nakamura, J; Nomoto, H; Sawamura, Y; Shimatsu, A; Sugino, H; Suzuki, M; Takahashi, Y; Yamashita, Y; Yuno, A, 2021) |
| "Acute hyperglycemia was induced by IP injection of dextrose 30 minutes before ischemia." | 1.33 | Why does acute hyperglycemia worsen the outcome of transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation. ( Bargalló, N; Chamorro, A; Falcón, C; Martín, A; Planas, AM; Rojas, S, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Yuno, A | 1 |
| Kenmotsu, Y | 1 |
| Takahashi, Y | 1 |
| Nomoto, H | 1 |
| Kameda, H | 1 |
| Cho, KY | 1 |
| Nakamura, A | 1 |
| Yamashita, Y | 1 |
| Nakamura, J | 1 |
| Nakakubo, S | 1 |
| Kamada, K | 1 |
| Suzuki, M | 1 |
| Sugino, H | 1 |
| Inoshita, N | 1 |
| Konno, S | 1 |
| Miyoshi, H | 1 |
| Atsumi, T | 1 |
| Sawamura, Y | 1 |
| Shimatsu, A | 1 |
| Kadoya, M | 1 |
| Kurajoh, M | 1 |
| Miyoshi, A | 1 |
| Shoji, T | 1 |
| Terada, T | 1 |
| Nakamoto, Y | 1 |
| Tsukamoto, Y | 1 |
| Moriwaki, Y | 1 |
| Hirota, S | 1 |
| Koyama, H | 1 |
| Martín, A | 1 |
| Rojas, S | 1 |
| Chamorro, A | 1 |
| Falcón, C | 1 |
| Bargalló, N | 1 |
| Planas, AM | 1 |
3 other studies available for metyrapone and Disease Exacerbation
| Article | Year |
|---|---|
Successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia.
Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adult; Amides; Benzamidines; Combined Modality Therapy; C | 2021 |
Ectopic adrenocorticotropic hormone syndrome associated with olfactory neuroblastoma: acquirement of adrenocorticotropic hormone expression during disease course as shown by serial immunohistochemistry examinations.
Topics: Adrenocorticotropic Hormone; Blood Glucose; Disease Progression; Eosinophils; Esthesioneuroblastoma, | 2018 |
Why does acute hyperglycemia worsen the outcome of transient focal cerebral ischemia? Role of corticosteroids, inflammation, and protein O-glycosylation.
Topics: Adrenal Cortex Hormones; Animals; Antimetabolites; Disease Progression; Glycosylation; Hyperglycemia | 2006 |