metyrapone has been researched along with Diabetes Mellitus, Type 1 in 7 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Excerpt | Relevance | Reference |
|---|---|---|
| "poorly controlled IDDM)." | 2.67 | Stimulus specificity of defects in counterregulatory hormone secretion in insulin-dependent diabetes mellitus: effect of glycemic control. ( Kinsley, BT; Simonson, DC; Utzschneider, K; Widom, B, 1994) |
| "Ectopic Cushing's syndrome was suspected on the basis of high urinary free cortisol excretion (UFC) with a blunted circadian profile of serum cortisol and measurable plasma ACTH concentrations." | 1.29 | Misdiagnosis of Cushing's syndrome in a patient receiving rifampicin therapy for tuberculosis. ( Alì, A; Angeli, A; Boccuzzi, A; Borretta, G; Cesario, F; Magro, G; Reimondo, G; Terzolo, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 3 (42.86) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| RUVALCABA, RH | 2 |
| SAMOLS, E | 1 |
| KELLEY, VC | 2 |
| DITZEL, J | 1 |
| Terzolo, M | 1 |
| Borretta, G | 1 |
| Alì, A | 1 |
| Cesario, F | 1 |
| Magro, G | 1 |
| Boccuzzi, A | 1 |
| Reimondo, G | 1 |
| Angeli, A | 1 |
| Kinsley, BT | 2 |
| Widom, B | 1 |
| Utzschneider, K | 1 |
| Simonson, DC | 2 |
| Najjar, S | 1 |
| Ayash, MA | 1 |
1 trial available for metyrapone and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Stimulus specificity of defects in counterregulatory hormone secretion in insulin-dependent diabetes mellitus: effect of glycemic control.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Arginine; Blood Glucose; Diabetes Mellitus, Type 1; | 1994 |
6 other studies available for metyrapone and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
LIPOATROPHIC DIABETES. I. STUDIES CONCERNING ENDOCRINE FUNCTION AND CARBOHYDRATE METABOLISM.
Topics: Adolescent; Carbohydrate Metabolism; Diabetes Mellitus, Lipoatrophic; Diabetes Mellitus, Type 1; Dru | 1965 |
LIPOATROPHIC DIABETES. II. METABOLIC STUDIES CONCERNING THE MECHANISM OF LIPEMIA.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Cholesterol; Diabetes Mellitus, Lipoatrophic; | 1965 |
CLINICAL ASSESSMENT OF THE PERORAL METOPIRONE TEST.
Topics: Adenoma; Adenoma, Chromophobe; Adrenalectomy; Adrenocorticotropic Hormone; Cushing Syndrome; Diabete | 1965 |
Misdiagnosis of Cushing's syndrome in a patient receiving rifampicin therapy for tuberculosis.
Topics: Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushing Syndrome; Diabetes Mell | 1995 |
Evidence for a hypothalamic-pituitary versus adrenal cortical effect of glycemic control on counterregulatory hormone responses to hypoglycemia in insulin-dependent diabetes mellitus.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Adult; Blood Glucose; Diabetes Mellitus, Type 1; Epinep | 1996 |
The Mauriac syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Child; Depression, Chemical; Dexamethasone; Diabetes Mel | 1974 |