metyrapone has been researched along with Cushing's Syndrome in 389 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifteen patients with endogenous Cushing's syndrome were treated with metyrapone and/or amino-glutethimide." | 9.05 | Aminoglutethimide and metyrapone in the management of Cushing's syndrome. ( Adamson, U; Sjöberg, HE; Thorén, M, 1985) |
| "Steroidogenesis inhibitors such as metyrapone (MTP) and osilodrostat (ODT) have a key role in the medical treatment of endogenous Cushing's Syndrome (ECS)." | 8.31 | LC-MS/MS method for simultaneous quantification of osilodrostat and metyrapone in human plasma from patients treated for Cushing's Syndrome. ( Balakirouchenane, D; Bertherat, J; Blanchet, B; Bonnet-Serrano, F; Choi, M; Declèves, X; Groussin, L; Khoudour, N; Puszkiel, A; Vasseur, A; Vidal, M, 2023) |
| "Metyrapone and ketoconazole, frequently used steroidogenesis inhibitors for treatment of Cushing syndrome, can be associated with side effects and limited efficacy." | 7.91 | Osilodrostat Is a Potential Novel Steroidogenesis Inhibitor for the Treatment of Cushing Syndrome: An In Vitro Study. ( Creemers, SG; de Jong, FH; de Rijke, YB; Feelders, RA; Franssen, GJH; Hofland, LJ; van Koetsveld, PM, 2019) |
| "Our objective was to assess the efficacy and safety of combination therapy with mitotane, metyrapone, and ketoconazole in severe ACTH-dependent Cushing's syndrome." | 7.77 | Mitotane, metyrapone, and ketoconazole combination therapy as an alternative to rescue adrenalectomy for severe ACTH-dependent Cushing's syndrome. ( Baudin, E; Blanchard, A; Brailly-Tabard, S; Chanson, P; Droumaguet, C; Gautier, JF; Jublanc, C; Kamenický, P; Leboulleux, S; Salenave, S; Schlumberger, M; Young, J, 2011) |
| "We present a case of McCune-Albright syndrome revealed by a Cushing's syndrome treated by metyrapone." | 7.73 | [Treatment with metyrapone of Cushing's syndrome revealing McCune-Albright syndrome]. ( Azzabi, O; Ben Ammar, B; Ben Hariz, M; Ben Mrad, N; Halioui-Louhaichi, S; Maherzi, A; Nefzi, L, 2005) |
| "We wished to develop optimal criteria for interpreting the single-dose overnight metyrapone test and to compare the diagnostic efficiency of the overnight and the standard 6-dose metyrapone tests for the differential diagnosis of ACTH-dependent Cushing's syndrome." | 7.69 | A comparison of the overnight and the standard metyrapone test for the differential diagnosis of adrenocorticotrophin-dependent Cushing's syndrome. ( Avgerinos, PC; Cutler, GB; Nieman, LK; Oldfield, EH, 1996) |
| "18 patients were studied on 21 occasions: three with Cushing's disease without metyrapone treatment prior to IPSS (M-), 11 with Cushing's disease with metyrapone pretreatment (M+), three with ectopic ACTH syndrome, and one with pseudo-Cushing's syndrome." | 7.69 | Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome. ( Atkinson, RL; Cameron, DP; Cuneo, RC; Harper, J; Lee, W; Mitchell, K; Salkield, I; Ward, G, 1997) |
| "To develop criteria for interpreting results of the metyrapone test for the differential diagnosis of the adrenocorticotropin (ACTH)-dependent Cushing syndrome and to compare its diagnostic accuracy with that of the high-dose dexamethasone suppression test." | 7.69 | The metyrapone and dexamethasone suppression tests for the differential diagnosis of the adrenocorticotropin-dependent Cushing syndrome: a comparison. ( Avgerinos, PC; Cutler, GB; Nieman, LK; Oldfield, EH; Yanovski, JA, 1994) |
| "To analyse the clinical and biochemical effects of metyrapone in the treatment of Cushing's syndrome." | 7.68 | Short and long-term responses to metyrapone in the medical management of 91 patients with Cushing's syndrome. ( Besser, GM; Grossman, AB; Howlett, TA; Perry, L; Rees, LH; Trainer, PJ; Verhelst, JA; Wass, JA, 1991) |
| "Cushing's syndrome due to bronchial carcinoid tumors that secrete adrenocorticotropin (ACTH) may be difficult to distinguish from pituitary Cushing's disease, since the responses to dexamethasone and metyrapone are sometimes similar." | 7.67 | Ectopic ACTH syndrome caused by a bronchial carcinoid tumor responsive to dexamethasone, metyrapone, and corticotropin-releasing factor. ( Abboud, C; Carey, RM; Carney, JA; Malchoff, CD; Orth, DN; Pairolero, PC, 1988) |
| "The adrenostatic effect of metyrapone (Metopiron) and aminoglutethimide (Orimeten) was assessed retrospectively in ten patients with ACTH-dependent Cushing's syndrome, four of them with the ectopic form." | 7.67 | [Adrenostatic treatment of ACTH-dependent Cushing syndrome using metyrapone and aminoglutethimide]. ( Allolio, B; Jaursch-Hancke, C; Kaulen, D; Reincke, M; Winkelmann, W, 1987) |
| "Eighteen patients with Cushing's syndrome (16 pituitary-dependent Cushing's disease, 1 ectopic ACTH syndrome, 1 primary adrenal adenoma) were given a combination of aminoglutethimide and metyrapone, with the object of controlling cortisol overproduction using less toxic doses than would be required with each drug alone." | 7.65 | Drug controlled of Cushing's syndrome. Combined aminoglutethimide and metyrapone therapy. ( Burke, CW; Burley, DM; Child, DF; Fraser, TR; Rees, LH, 1976) |
| "To control hypercortisolism, the patient was treated with metyrapone." | 6.41 | Recurrent ACTH-independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone. ( Dokoupilová, M; Hána, V; Marek, J; Plavka, R, 2001) |
| "Osilodrostat is a new 11β-hydroxylase inhibitor with a mode of action analogous to Metyrapone." | 5.72 | Differences in the spectrum of steroidogenic enzyme inhibition between Osilodrostat and Metyrapone in ACTH-dependent Cushing syndrome patients. ( Assié, G; Baron, S; Bertherat, J; Bessiene, L; Blanchet, B; Bonnet-Serrano, F; Bricaire, L; Groussin, L; Guibourdenche, J; Guignat, L; Laguillier-Morizot, C; Poirier, J; Vaczlavik, A, 2022) |
| "Metyrapone (MET) is an inhibitor of 11β-hydroxylase: retrospective studies reported a decrease of cortisol secretion in 50% of cases." | 5.48 | Metyrapone treatment in Cushing's syndrome: a real-life study. ( Albiger, N; Antonelli, G; Barbot, M; Boscaro, M; Ceccato, F; Plebani, M; Sabbadin, C; Scaroni, C; Watutantrige-Fernando, S; Zilio, M, 2018) |
| "The ketoconazole was shift to metyrapone but afterwards ketoconazole was added again." | 5.46 | A successful case of pregnancy in a woman with ACTH-independent Cushing's syndrome treated with ketoconazole and metyrapone. ( Michalak, R; Zieleniewski, W, 2017) |
| "Hypercortisolism was successfully controlled with metyrapone, which was started at 8 weeks of gestation." | 5.33 | Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy. ( Blanco, C; Maqueda, E; Rodriguez, A; Rubio, JA, 2006) |
| "Treatment with metyrapone thus appears a good therapy for AIMAH, but its effectiveness has not, to our knowledge, been studied." | 5.31 | Rational, effective metyrapone treatment of ACTH-independent bilateral macronodular adrenocortical hyperplasia (AIMAH). ( Nomura, K; Obara, T; Omori, K; Omori, N; Takano, K, 2001) |
| "The hypercortisolism was controlled with metyrapone until elective delivery of the fetus by Caesarean section at 34 weeks gestation because of a decline in growth." | 5.29 | ACTH-independent Cushing's syndrome in pregnancy with spontaneous resolution after delivery: control of the hypercortisolism with metyrapone. ( Close, CF; Mann, MC; Taylor, KG; Watts, JF, 1993) |
| "Aldosterone excretion was high, normal, or low in each of the three types of Cushing's syndrome." | 5.26 | Deoxycorticosterone and aldosterone excretion in Cushing's syndrome. ( Cassar, J; Joplin, GF; Kelly, WF; Loizou, S; Mashiter, K, 1980) |
| "Cortisol was measured in serum from three patient groups: (1) patients receiving metyrapone (n = 112 samples from 10 patients); (2) control group of patients diagnosed with Cushing's syndrome currently receiving no treatment (n = 31); and (3) control group of patients with no adrenal pathology and not receiving medication known to interfere in cortisol immunoassay (n = 67)." | 5.15 | Comparison of serum cortisol measurement by immunoassay and liquid chromatography-tandem mass spectrometry in patients receiving the 11β-hydroxylase inhibitor metyrapone. ( Brabant, G; Darby, D; Keevil, BG; Monaghan, PJ; Owen, LJ; Trainer, PJ, 2011) |
| "Fifteen patients with endogenous Cushing's syndrome were treated with metyrapone and/or amino-glutethimide." | 5.05 | Aminoglutethimide and metyrapone in the management of Cushing's syndrome. ( Adamson, U; Sjöberg, HE; Thorén, M, 1985) |
| "Inhibitors of steroid synthesis such as o,p'-DDD, aminoglutethimide, metyrapone, trilostane and ketoconazole are usually used for treatment of Cushing's syndrome in order to reduce the steroid production in the patients showing several complications, including severe hypertension and diabetes mellitus, and also an incomplete remission after the surgical treatment." | 4.79 | [Clinical usefulness of pharmacological treatment of Cushing's syndrome]. ( Nishikawa, T; Saito, J, 1994) |
| "Steroidogenesis inhibitors such as metyrapone (MTP) and osilodrostat (ODT) have a key role in the medical treatment of endogenous Cushing's Syndrome (ECS)." | 4.31 | LC-MS/MS method for simultaneous quantification of osilodrostat and metyrapone in human plasma from patients treated for Cushing's Syndrome. ( Balakirouchenane, D; Bertherat, J; Blanchet, B; Bonnet-Serrano, F; Choi, M; Declèves, X; Groussin, L; Khoudour, N; Puszkiel, A; Vasseur, A; Vidal, M, 2023) |
| "Metyrapone and ketoconazole, frequently used steroidogenesis inhibitors for treatment of Cushing syndrome, can be associated with side effects and limited efficacy." | 3.91 | Osilodrostat Is a Potential Novel Steroidogenesis Inhibitor for the Treatment of Cushing Syndrome: An In Vitro Study. ( Creemers, SG; de Jong, FH; de Rijke, YB; Feelders, RA; Franssen, GJH; Hofland, LJ; van Koetsveld, PM, 2019) |
| "Steroidogenesis inhibitors, such as ketoconazole (KTZ) and metyrapone (MTP), are used to lower hypercortisolism in patients with Cushing's syndrome (CS)." | 3.85 | A polymorphism in the CYP17A1 gene influences the therapeutic response to steroidogenesis inhibitors in Cushing's syndrome. ( Aulinas, A; Glad, CA; Johannsson, G; Ragnarsson, O; Valassi, E; Webb, SM, 2017) |
| "We report a case of severe Cushing's syndrome developing into life-threatening acute respiratory distress syndrome with cryptococcus and cytomegalovirus co-infection soon after hypercortisolism treatment using metyrapone, an 11-beta-hydroxylase inhibitor." | 3.79 | [A case of acute respiratory distress syndrome caused by cryptococcus and cytomegalovirus co-infection after Cushing's syndrome treatment]. ( Goto, T; Sato, E; Takata, T; Tamura, K; Yanase, T, 2013) |
| "To evaluate the outcome of preoperative therapy with ketoconazole (KTZ) and/or metyrapone (MTP) in previously untreated patients with Cushing's syndrome (CS)." | 3.78 | A reappraisal of the medical therapy with steroidogenesis inhibitors in Cushing's syndrome. ( Crespo, I; Gich, I; Rodríguez, J; Valassi, E; Webb, SM, 2012) |
| "Our objective was to assess the efficacy and safety of combination therapy with mitotane, metyrapone, and ketoconazole in severe ACTH-dependent Cushing's syndrome." | 3.77 | Mitotane, metyrapone, and ketoconazole combination therapy as an alternative to rescue adrenalectomy for severe ACTH-dependent Cushing's syndrome. ( Baudin, E; Blanchard, A; Brailly-Tabard, S; Chanson, P; Droumaguet, C; Gautier, JF; Jublanc, C; Kamenický, P; Leboulleux, S; Salenave, S; Schlumberger, M; Young, J, 2011) |
| "Current guidance recommends titrating the dose of metyrapone against serum cortisol concentration, in patients under medical management of Cushing's syndrome." | 3.76 | Cortisol measurement in patients receiving metyrapone therapy. ( Halsall, DJ; Keevil, BG; Owen, LJ, 2010) |
| "We present a case of McCune-Albright syndrome revealed by a Cushing's syndrome treated by metyrapone." | 3.73 | [Treatment with metyrapone of Cushing's syndrome revealing McCune-Albright syndrome]. ( Azzabi, O; Ben Ammar, B; Ben Hariz, M; Ben Mrad, N; Halioui-Louhaichi, S; Maherzi, A; Nefzi, L, 2005) |
| "Eighteen patients with Cushing's syndrome, five patients with hypocortisolemia, seven patients undergoing metyrapone testing, and 14 controls were studied." | 3.73 | Expression of the human glucocorticoid receptor splice variants alpha, beta, and P in peripheral blood mononuclear leukocytes in healthy controls and in patients with hyper- and hypocortisolism. ( Brinkmann, AO; de Jong, FH; Feelders, RA; Hagendorf, A; Koper, JW; Lamberts, SW, 2005) |
| "To develop criteria for interpreting results of the metyrapone test for the differential diagnosis of the adrenocorticotropin (ACTH)-dependent Cushing syndrome and to compare its diagnostic accuracy with that of the high-dose dexamethasone suppression test." | 3.69 | The metyrapone and dexamethasone suppression tests for the differential diagnosis of the adrenocorticotropin-dependent Cushing syndrome: a comparison. ( Avgerinos, PC; Cutler, GB; Nieman, LK; Oldfield, EH; Yanovski, JA, 1994) |
| "18 patients were studied on 21 occasions: three with Cushing's disease without metyrapone treatment prior to IPSS (M-), 11 with Cushing's disease with metyrapone pretreatment (M+), three with ectopic ACTH syndrome, and one with pseudo-Cushing's syndrome." | 3.69 | Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome. ( Atkinson, RL; Cameron, DP; Cuneo, RC; Harper, J; Lee, W; Mitchell, K; Salkield, I; Ward, G, 1997) |
| "We wished to develop optimal criteria for interpreting the single-dose overnight metyrapone test and to compare the diagnostic efficiency of the overnight and the standard 6-dose metyrapone tests for the differential diagnosis of ACTH-dependent Cushing's syndrome." | 3.69 | A comparison of the overnight and the standard metyrapone test for the differential diagnosis of adrenocorticotrophin-dependent Cushing's syndrome. ( Avgerinos, PC; Cutler, GB; Nieman, LK; Oldfield, EH, 1996) |
| "The basal levels of 19-hydroxyandrostenedione in Cushing's disease were elevated (mean +/- SD; 323 +/- 193 pmol/l, n = 13), while those in Cushing's syndrome due to adrenal adenoma were low (92 +/- 24 pmol/l, n = 7), compared to those in normal subjects (117 +/- 33 pmol/l, n = 54)." | 3.68 | Elevated plasma 19-hydroxyandrostenedione levels in Cushing's disease: stimulation with ACTH and inhibition with metyrapone. ( Miura, K; Morita, H; Mune, T; Murayama, M; Yamakita, N; Yasuda, K, 1993) |
| "To analyse the clinical and biochemical effects of metyrapone in the treatment of Cushing's syndrome." | 3.68 | Short and long-term responses to metyrapone in the medical management of 91 patients with Cushing's syndrome. ( Besser, GM; Grossman, AB; Howlett, TA; Perry, L; Rees, LH; Trainer, PJ; Verhelst, JA; Wass, JA, 1991) |
| "The adrenostatic effect of metyrapone (Metopiron) and aminoglutethimide (Orimeten) was assessed retrospectively in ten patients with ACTH-dependent Cushing's syndrome, four of them with the ectopic form." | 3.67 | [Adrenostatic treatment of ACTH-dependent Cushing syndrome using metyrapone and aminoglutethimide]. ( Allolio, B; Jaursch-Hancke, C; Kaulen, D; Reincke, M; Winkelmann, W, 1987) |
| "We describe thirty-one patients with Cushing's syndrome, with the object of evaluating the relative merit of the Dexamethasone suppression test, Metyrapone test and Corticotrophin Releasing Factor (CRF) test in classifying the syndrome." | 3.67 | [Investigation of Cushing's syndrome. The diagnostic value of the dexamethasone suppression test, the metopirone test and the CRF test]. ( Frey, H; Johannesen, O; Jørgensen, H; Norman, N, 1989) |
| "Cushing's syndrome due to bronchial carcinoid tumors that secrete adrenocorticotropin (ACTH) may be difficult to distinguish from pituitary Cushing's disease, since the responses to dexamethasone and metyrapone are sometimes similar." | 3.67 | Ectopic ACTH syndrome caused by a bronchial carcinoid tumor responsive to dexamethasone, metyrapone, and corticotropin-releasing factor. ( Abboud, C; Carey, RM; Carney, JA; Malchoff, CD; Orth, DN; Pairolero, PC, 1988) |
| " In congenital adrenal hyperplasia, plasma ACTH concentrations mirror, together with 17-alpha-hydroxyprogesterone, the extent of ACTH suppression." | 3.67 | Plasma ACTH in diagnosis and control of adrenal disorders. ( Baumann, JB; Eberle, AN; Girard, J, 1986) |
| "The direct effects of etomidate, ketoconazole, miconazole and metyrapone were investigated on the secretion of cortisol and its precursors by dispersed cells from the adrenal cortex of a normal individual and four patients with Cushing's syndrome." | 3.67 | Differential effects of the imidazole derivatives etomidate, ketoconazole and miconazole and of metyrapone on the secretion of cortisol and its precursors by human adrenocortical cells. ( Bons, EG; Bruining, HA; de Jong, FH; Lamberts, SW, 1987) |
| " Conservative treatment with metyrapone suppressed the Cushing syndrome." | 3.66 | [Successful conservative treatment of bronchial carcinoid with Cushing's syndrome due to ectopic ACTH production]. ( Euler, HH; Herrlinger, JD; Kirmse, L; Kleine, L; Löffler, H; Müller-Hermelink, HK, 1983) |
| "Subnormal plasma 11-deoxycortisol (compound S) responses to metyrapone were found in patients with adrenal insufficiency or with Cushing syndrome caused by adrenal tumors and in those receiving long-term glucocorticoid or diphenylhydantoin sodium therapy." | 3.65 | Single-dose metyrapone test: review of a four-year experience. ( Jubiz, W; Meikle, AW; Spiger, M; Tylor, FH; West, CD, 1975) |
| "Eighteen patients with Cushing's syndrome (16 pituitary-dependent Cushing's disease, 1 ectopic ACTH syndrome, 1 primary adrenal adenoma) were given a combination of aminoglutethimide and metyrapone, with the object of controlling cortisol overproduction using less toxic doses than would be required with each drug alone." | 3.65 | Drug controlled of Cushing's syndrome. Combined aminoglutethimide and metyrapone therapy. ( Burke, CW; Burley, DM; Child, DF; Fraser, TR; Rees, LH, 1976) |
| "However, hypercortisolism may persist or recur postoperatively; in other cases, the underlying tumor may not be resectable or its location may not be known." | 2.72 | Adrenally Directed Medical Therapies for Cushing Syndrome. ( Tritos, NA, 2021) |
| "Osilodrostat has been shown to be highly effective at maintaining normal urinary free cortisol in patients with CD." | 2.72 | Updates in adrenal steroidogenesis inhibitors for Cushing's syndrome - A practical guide. ( Fleseriu, M; Han, AJ; Varlamov, EV, 2021) |
| "Severe hypercortisolism is characterized as a life-threatening endocrine condition in patients with Cushing syndrome, usually related to the concomitant onset of one or more comorbidities, requiring rapid normalization of cortisol concentrations and aggressive treatment of associated complications." | 2.72 | Medical therapy in severe hypercortisolism. ( Boguszewski, CL; Marques, JVO, 2021) |
| "Medical therapy to control hypercortisolism in adrenal Cushing's syndrome is currently not the first-line therapy." | 2.66 | What is the role of medical therapy in adrenal-dependent Cushing's syndrome? ( Braun, LT; Reincke, M, 2020) |
| "Treatment with metyrapone was started before pituitary surgery." | 2.66 | Pneumocystis pneumonia can complicate medical treatment of hypercortisolism even in outpatients with Cushing's disease. ( Carreau, A; Chabre, O; Cristante, J; Lepelley, M; Mallaret, M, 2020) |
| "The Metyrapone was given, the morning, in perfusion intravenous of saline serum over 2 hours." | 2.64 | [Changes in plasma level of corticotropin after intravenous injection of metyrapone. Value of this test in pituitary pathology]. ( Gabaude, B; Huguenin, A; Javalet, A; Murie, N, 1977) |
| "Bromocriptine therapy was discontinued after 16 weeks in the second patient due to the development of mental depression." | 2.64 | ACTH and cortisol response to bromocriptine, and results of long-term therapy, in Cushing's disease. ( Kennedy, AL; Montgomery, DA; Sheridan, B, 1978) |
| "Pregnancy-induced Cushing's syndrome is exceptionally rare with fewer than ten cases reported in the world literature and none in Australia or New Zealand." | 2.48 | Pregnancy-induced Cushing's syndrome in recurrent pregnancies: case report and literature review. ( Achong, N; D'Emden, M; Fagermo, N; Mortimer, R, 2012) |
| "Cushing's syndrome is associated with serious morbidity and increased mortality." | 2.46 | Medical treatment of Cushing's syndrome: adrenal-blocking drugs and ketaconazole. ( de Herder, WW; Feelders, RA; Hofland, LJ, 2010) |
| "Active Cushing's syndrome is associated with insulin resistance induced by the high and prolonged circulating level of glucocorticoids." | 2.46 | Management of diabetes mellitus in Cushing's syndrome. ( Munir, A; Newell-Price, J, 2010) |
| "Cushing's syndrome is a complex endocrine condition with potential serious complications if untreated or inadequately treated." | 2.45 | Drugs in the medical treatment of Cushing's syndrome. ( Schteingart, DE, 2009) |
| "The most common cause of endogenous Cushing's disease in children older than 7 years is ACTH-dependent Cushing's disease (85%)." | 2.45 | [Cushing's syndrome: special issues]. ( Goñi Iriarte, MJ, 2009) |
| "Thus, we should treat Cushing's syndrome as soon as possible, since many complications, including cardiovascular diseases and infections, will soon occur when the definite diagnosis is delayed." | 2.44 | [Medical treatment for Cushing's syndrome]. ( Nishikawa, T; Omura, M; Saito, J, 2008) |
| "ACTH-dependent Cushing's syndrome is a heterogeneous disorder requiring a multidisciplinary and individualized approach to patient management." | 2.44 | Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement. ( Bertagna, X; Bertherat, J; Biller, BM; Boscaro, M; Buchfelder, M; Colao, A; Grossman, AB; Hermus, AR; Hofland, LJ; Klibanski, A; Lacroix, A; Lindsay, JR; Melmed, S; Newell-Price, J; Nieman, LK; Petersenn, S; Sonino, N; Stalla, GK; Stewart, PM; Swearingen, B; Vance, ML; Wass, JA, 2008) |
| "Cushing's syndrome is an uncommon disorder, but one that often presents diagnostic challenges to the managing physician." | 2.42 | Dynamic tests in the diagnosis and differential diagnosis of Cushing's syndrome. ( Grossman, AB; Morris, DG, 2003) |
| "To control hypercortisolism, the patient was treated with metyrapone." | 2.41 | Recurrent ACTH-independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone. ( Dokoupilová, M; Hána, V; Marek, J; Plavka, R, 2001) |
| "Non-iatrogenic Cushing's syndrome has been associated primarily with three entities: pituitary-dependent processes due to pituitary adenomas or microadenomas causing adrenal hyperplasia; pituitary-independent primary adrenal causes, predominantly unilateral adenomas, rarely multiple adenomas or adrenal carcinoma; ectopic sources of adrenocorticotropic hormone (ACTH) production." | 2.37 | Primary adrenocortical nodular dysplasia, a distinct subtype of Cushing's syndrome. Case report and review of the literature. ( Cathey, WJ; Larsen, JL; Odell, WD, 1986) |
| "Treatment with metyrapone or o,p'-DDD can always induce a clinical remission but not a cure, and neurotransmitter therapy may be effective in a minority of cases." | 2.37 | Cushing's syndrome. ( Besser, GM; Howlett, TA; Rees, LH, 1985) |
| "Osilodrostat is a new 11β-hydroxylase inhibitor with a mode of action analogous to Metyrapone." | 1.72 | Differences in the spectrum of steroidogenic enzyme inhibition between Osilodrostat and Metyrapone in ACTH-dependent Cushing syndrome patients. ( Assié, G; Baron, S; Bertherat, J; Bessiene, L; Blanchet, B; Bonnet-Serrano, F; Bricaire, L; Groussin, L; Guibourdenche, J; Guignat, L; Laguillier-Morizot, C; Poirier, J; Vaczlavik, A, 2022) |
| "Medical therapy can be used to treat Cushing syndrome and can result in improvement in the cardiovascular pathology." | 1.72 | Cushing syndrome as a failed cardiac screen in a patient with McCune-Albright syndrome: a case report. ( Al Zubeidi, H; Diaz-Thomas, A; Foster, C, 2022) |
| "Ruling out other causes, paraneoplastic hypercortisolism was diagnosed." | 1.51 | Hypokalaemic metabolic alkalosis, hypertension and diabetes: what is the link. ( Cathomas, R; Fehr, T; Kamber, N; Vögelin, M, 2019) |
| "Although endogenous Cushing's syndrome is rare in older people, it should always be considered among the differential diagnosis of behavioural disorders." | 1.48 | Behaviour disorder caused by Cushing's syndrome in an older person. ( Abbate, C; Belloni, G; Cesari, M; Chiodini, I; Damanti, S; Lucchi, T; Mandelli, C; Mari, D; Nestola, T, 2018) |
| "Metyrapone (MET) is an inhibitor of 11β-hydroxylase: retrospective studies reported a decrease of cortisol secretion in 50% of cases." | 1.48 | Metyrapone treatment in Cushing's syndrome: a real-life study. ( Albiger, N; Antonelli, G; Barbot, M; Boscaro, M; Ceccato, F; Plebani, M; Sabbadin, C; Scaroni, C; Watutantrige-Fernando, S; Zilio, M, 2018) |
| "Surgery is the definitive treatment of Cushing's syndrome (CS) but medications may also be used as a first-line therapy." | 1.48 | Preoperative medical treatment in Cushing's syndrome: frequency of use and its impact on postoperative assessment: data from ERCUSYN. ( Bolanowski, M; Brue, T; Chabre, O; Chanson, P; Droste, M; Fajardo, C; Feelders, RA; Franz, H; Kastelan, D; Komerdus, I; Krsek, M; Maiter, D; Netea-Maier, R; Pfeifer, M; Reincke, M; Santos, A; Strasburger, CJ; Tabarin, A; Tóth, M; Trainer, PJ; Tsagarakis, S; Valassi, E; Wass, JAH; Webb, SM; Yaneva, M, 2018) |
| "The ketoconazole was shift to metyrapone but afterwards ketoconazole was added again." | 1.46 | A successful case of pregnancy in a woman with ACTH-independent Cushing's syndrome treated with ketoconazole and metyrapone. ( Michalak, R; Zieleniewski, W, 2017) |
| "The hypercortisolism is a rare endocrine disease characterized by an autonomous steroid secretion or excessive adrenal stimulation by ACTH." | 1.43 | [Indications and future perspectives in the pharmacological treatment of hypercortisolism]. ( Stigliano, A; Toscano, V, 2016) |
| "We report a case of McCune-Albright syndrome with CS treated with metyrapone for 30 months with prolonged remission after a 12-year follow-up." | 1.43 | [Recovery of Cushing syndrome revealing McCune-Albright syndrome]. ( Azzabi, O; Dridi, Y; Fetni, I; Halioui-Louhaichi, S; Maherzi, A; Selmi, I; Siala, N, 2016) |
| "Treatment with metyrapone led to a swift improvement of the patient's symptoms." | 1.42 | [Cushing's syndrome in a manic patient with a long-standing bipolar disorder: cause or coincidence?]. ( Bartel, M; de Witte, LD; Kleijweg, M; Smits, RB; Valk, GD; Vergeer, M; Vinkers, CH, 2015) |
| "The baby girl underwent medical treatment of Cushing's syndrome with metyrapone which was followed by a rapid recovery." | 1.42 | Neonatal McCune-Albright syndrome with systemic involvement: a case report. ( Dias, P; Gouveia, R; Lourenço, R; Oliveira, G; Sousa, AB, 2015) |
| "Cushing syndrome was diagnosed on the basis of a markedly elevated 24-hour urine free cortisol level and classic cushingoid features." | 1.35 | A patient with ectopic cortisol production derived from malignant testicular masses. ( Dluhy, RG; Jain, SH; Nosé, V; Sadow, PM, 2008) |
| "Hypercortisolism was successfully controlled with metyrapone, which was started at 8 weeks of gestation." | 1.33 | Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy. ( Blanco, C; Maqueda, E; Rodriguez, A; Rubio, JA, 2006) |
| "Treatment with metyrapone thus appears a good therapy for AIMAH, but its effectiveness has not, to our knowledge, been studied." | 1.31 | Rational, effective metyrapone treatment of ACTH-independent bilateral macronodular adrenocortical hyperplasia (AIMAH). ( Nomura, K; Obara, T; Omori, K; Omori, N; Takano, K, 2001) |
| "The metyrapone test is a useful test in the assessment of outcome of pituitary surgery for Cushing's disease, with a sensitivity of 100% and a specificity of 75% for the early detection of patients at risk of a relapse." | 1.30 | Postoperative metyrapone test in the early assessment of outcome of pituitary surgery for Cushing's disease. ( de Herder, WW; de Jong, FH; Lamberts, SW; van Aken, MO; van der Lely, AJ, 1997) |
| "Ketoconazole treatment had success in to normalize the 24-hour UFC in all patients, except for the case of adrenal carcinoma." | 1.30 | [Cushing's syndrome: clinical study of fifteen cases]. ( Alvarez Barreiro, JA; Calvo Romero, JM; Diaz Pérez de Madrid, J; Morales Pérez, F, 1998) |
| "Ectopic Cushing's syndrome was suspected on the basis of high urinary free cortisol excretion (UFC) with a blunted circadian profile of serum cortisol and measurable plasma ACTH concentrations." | 1.29 | Misdiagnosis of Cushing's syndrome in a patient receiving rifampicin therapy for tuberculosis. ( Alì, A; Angeli, A; Boccuzzi, A; Borretta, G; Cesario, F; Magro, G; Reimondo, G; Terzolo, M, 1995) |
| "The hypercortisolism was controlled with metyrapone until elective delivery of the fetus by Caesarean section at 34 weeks gestation because of a decline in growth." | 1.29 | ACTH-independent Cushing's syndrome in pregnancy with spontaneous resolution after delivery: control of the hypercortisolism with metyrapone. ( Close, CF; Mann, MC; Taylor, KG; Watts, JF, 1993) |
| "Familial Cushing's syndrome is rare, and when it occurs, it is usually associated with primary micronodular dysplasia." | 1.29 | Familial adrenocorticotropin-independent Cushing's syndrome with bilateral macronodular adrenal hyperplasia. ( Aron, DC; Engeland, WC; Findlay, JC; Sheeler, LR, 1993) |
| "Metyrapone was administered orally at a dosage of 65 mg/kg of body weight, every 12 hours." | 1.29 | Use of metyrapone to treat pituitary-dependent hyperadrenocorticism in a cat with large cutaneous wounds. ( Daley, CA; Powers, RD; Schick, RO; Zerbe, CA, 1993) |
| " A marked clinical and laboratory improvement was noted in two patients, in another some clinical and laboratory improvement was obtained only after bromocriptine dosage was increased to 15 mg/day." | 1.27 | Cushing's disease: clinical and laboratory response to bromocriptine therapy. ( Antunes, RC; de Pinho, MO; Francalanci, CC; Franco, S; Lima, MB, 1984) |
| "In vitro perifusion of the pituitary adenoma obtained by surgery revealed that o-CRF also stimulated ACTH and beta-EP release in a dose-responsive manner (10(-9)M 10(-5)M) and that dopamine suppressed their basal secretion." | 1.27 | Effect of ovine corticotrophin releasing factor, bromocriptine, and dopamine on release of ACTH and beta-endorphin in a patient with Cushing's disease. ( Fujita, T; Hirata, Y; Nakashima, H; Tomita, M; Uchihashi, M, 1985) |
| "Metyrapone has been labelled with radioiodine selectively in the 4'-position of ring B." | 1.27 | Synthesis of radioiodinated metyrapone--a potential adrenal imaging agent. ( Robien, W; Zolle, I, 1983) |
| "The Cushing's syndrome was controlled medically, and when the patient deteriorated clinically she received treatment with a combination of BCNU, adriamycin, and ftorafur." | 1.26 | Successful therapy of an ACTH-producing gastric carcinoid APUD tumor: report of a case and review of the literature. ( Callen, PW; Churg, A; Friedman, MA; Harbour, J; Marcus, FS, 1980) |
| "The patient's hypercortisolism disappeared following removal of the chromophobe adenoma through transphenoidal hypophysectomy." | 1.26 | Periodic remission in Cushing's disease with paradoxical dexamethasone response: an expression of periodic hormonogenesis. ( Liberman, B; Mesquita, CH; Tambascia, MA; Wajchenberg, BL, 1976) |
| "Metyrapone was used in the long-term management of 13 patients with pituitary-dependent bilateral adrenal hyperplasia (Cushing's disease)." | 1.26 | Metyrapone in long-term management of Cushing's disease. ( Besser, GM; Edwards, CR; Jeffcoate, WJ; Jones, AE; Rees, LH; Tomlin, S, 1977) |
| "The hypertension was alleviated by the administeration of dexamethasone in 2 of 3 patients with 17 alpha-hydroxylase deficiency." | 1.26 | Hypertension induced by adrenocortical dysfunction--hypertension in 17 alpha-hydroxylase deficiency and metopirone-induced hypertension. ( Kato, E; Kitajima, W; Kondo, K; Konishi, K; Matsuki, S; Nakamura, R; Ohguro, T; Oka, M; Ozawa, Y; Saito, I; Saruta, T; Yamagami, K, 1978) |
| " Long-term administration of cyproheptadine appeared to normalize excessive adrenocorticotropic hormone (ACTH) production by reducing the frequency and the peak levels of episodic secretion of ACTH." | 1.26 | Cyproheptadine in the control of Cushing's disease. ( Gann, DS; Hsu, TH; Russell, RP; Tsan, KW, 1981) |
| "Therefore, hypercortisolism probably selectively interferes with the regulation of PRL secretion at a suprahypophyseal level." | 1.26 | Regulation of prolactin secretion in patients with Cushing's disease. A comparative study on the effects of dexamethasone, lysine vasopressin and ACTH on prolactin secretion by the rat pituitary gland in vitro. ( de Quijada, M; Lamberts, SW; Visser, TJ, 1981) |
| "Aldosterone excretion was high, normal, or low in each of the three types of Cushing's syndrome." | 1.26 | Deoxycorticosterone and aldosterone excretion in Cushing's syndrome. ( Cassar, J; Joplin, GF; Kelly, WF; Loizou, S; Mashiter, K, 1980) |
| "Six nonadrenalectomized patients with pituitary tumors showed similar abnormalities of ACTH regulation." | 1.25 | Studies of ACTH secretion control in 116 cases of Cushing's syndrome. ( Binoux, M; Girard, F; Gourmelen, M; Luton, JP; Raux, MC, 1975) |
| "Treatment with metyrapone decreased her cortisol production and produced clinical remission of Cushing's syndrome." | 1.25 | The immunological hazard of Cushing's syndrome. ( Britton, S; Sjoberg, HE; Thorén, M, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 258 (66.32) | 18.7374 |
| 1990's | 51 (13.11) | 18.2507 |
| 2000's | 29 (7.46) | 29.6817 |
| 2010's | 37 (9.51) | 24.3611 |
| 2020's | 14 (3.60) | 2.80 |
| Authors | Studies |
|---|---|
| Emmerich, J | 1 |
| Hu, Q | 1 |
| Hanke, N | 1 |
| Hartmann, RW | 1 |
| Vega-Beyhart, A | 1 |
| Laguna-Moreno, J | 1 |
| Díaz-Catalán, D | 1 |
| Boswell, L | 1 |
| Mora, M | 1 |
| Halperin, I | 1 |
| Casals, G | 1 |
| Hanzu, FA | 1 |
| Bonnet-Serrano, F | 2 |
| Poirier, J | 1 |
| Vaczlavik, A | 1 |
| Laguillier-Morizot, C | 1 |
| Blanchet, B | 2 |
| Baron, S | 1 |
| Guignat, L | 1 |
| Bessiene, L | 1 |
| Bricaire, L | 2 |
| Groussin, L | 2 |
| Assié, G | 1 |
| Guibourdenche, J | 1 |
| Bertherat, J | 3 |
| Pivonello, R | 1 |
| Simeoli, C | 1 |
| Di Paola, N | 1 |
| Colao, A | 2 |
| Foster, C | 1 |
| Al Zubeidi, H | 1 |
| Diaz-Thomas, A | 1 |
| Lugat, A | 1 |
| Lasolle, H | 1 |
| François, M | 1 |
| Benhenda, N | 1 |
| Cornu, E | 1 |
| Cristante, J | 2 |
| Gitton, A | 1 |
| Hadoux, J | 1 |
| Kerlan, V | 1 |
| Le Bras, M | 1 |
| Mezzaroba, V | 1 |
| Puerto, M | 1 |
| Storey, C | 1 |
| Ouzounian, S | 1 |
| Donadille, B | 1 |
| Raverot, G | 1 |
| Drui, D | 1 |
| Haissaguerre, M | 2 |
| Balakirouchenane, D | 1 |
| Vasseur, A | 1 |
| Choi, M | 1 |
| Khoudour, N | 1 |
| Puszkiel, A | 1 |
| Vidal, M | 1 |
| Declèves, X | 1 |
| Braun, LT | 1 |
| Reincke, M | 5 |
| Newell-Price, J | 6 |
| Nieman, LK | 5 |
| Tabarin, A | 5 |
| Beretta, F | 1 |
| Dassie, F | 1 |
| Parolin, M | 1 |
| Boscari, F | 1 |
| Barbot, M | 2 |
| Busetto, L | 1 |
| Mioni, R | 1 |
| De Carlo, E | 1 |
| Scaroni, C | 2 |
| Fallo, F | 1 |
| Vettor, R | 1 |
| Maffei, P | 1 |
| Tritos, NA | 2 |
| Lepelley, M | 1 |
| Mallaret, M | 1 |
| Carreau, A | 1 |
| Chabre, O | 2 |
| Marques, JVO | 1 |
| Boguszewski, CL | 1 |
| Castinetti, F | 1 |
| Varlamov, EV | 1 |
| Han, AJ | 1 |
| Fleseriu, M | 1 |
| Valassi, E | 3 |
| Aulinas, A | 1 |
| Glad, CA | 1 |
| Johannsson, G | 1 |
| Ragnarsson, O | 1 |
| Webb, SM | 4 |
| Humayun, MA | 1 |
| Hart, T | 1 |
| Richardson, T | 1 |
| Claps, M | 1 |
| Cerri, S | 1 |
| Grisanti, S | 1 |
| Lazzari, B | 1 |
| Ferrari, V | 1 |
| Roca, E | 1 |
| Perotti, P | 1 |
| Terzolo, M | 2 |
| Sigala, S | 1 |
| Berruti, A | 1 |
| Franz, H | 1 |
| Brue, T | 1 |
| Feelders, RA | 4 |
| Netea-Maier, R | 1 |
| Tsagarakis, S | 1 |
| Yaneva, M | 1 |
| Droste, M | 1 |
| Komerdus, I | 1 |
| Maiter, D | 1 |
| Kastelan, D | 1 |
| Chanson, P | 3 |
| Pfeifer, M | 1 |
| Strasburger, CJ | 1 |
| Tóth, M | 1 |
| Krsek, M | 1 |
| Fajardo, C | 1 |
| Bolanowski, M | 1 |
| Santos, A | 1 |
| Trainer, PJ | 4 |
| Wass, JAH | 1 |
| Rouland, A | 1 |
| Nguyen, A | 1 |
| Fourmont, C | 1 |
| Lapray, M | 1 |
| Vergès, B | 1 |
| Petit, JM | 1 |
| Bouillet, B | 1 |
| Damanti, S | 1 |
| Abbate, C | 1 |
| Chiodini, I | 1 |
| Cesari, M | 1 |
| Nestola, T | 1 |
| Belloni, G | 1 |
| Mandelli, C | 1 |
| Mari, D | 1 |
| Lucchi, T | 1 |
| Ceccato, F | 1 |
| Zilio, M | 1 |
| Albiger, N | 1 |
| Antonelli, G | 1 |
| Plebani, M | 1 |
| Watutantrige-Fernando, S | 1 |
| Sabbadin, C | 1 |
| Boscaro, M | 3 |
| Ollivier, M | 1 |
| Ferriere, A | 1 |
| Vögelin, M | 1 |
| Cathomas, R | 1 |
| Kamber, N | 1 |
| Fehr, T | 1 |
| Creemers, SG | 1 |
| de Jong, FH | 6 |
| Franssen, GJH | 1 |
| de Rijke, YB | 1 |
| van Koetsveld, PM | 1 |
| Hofland, LJ | 3 |
| Goto, T | 1 |
| Takata, T | 1 |
| Sato, E | 1 |
| Tamura, K | 1 |
| Yanase, T | 2 |
| Ozawa, W | 1 |
| Sato, K | 1 |
| Miyakoshi, T | 1 |
| Nishio, S | 1 |
| Yamazaki, M | 1 |
| Suzuki, S | 2 |
| Komatsu, M | 1 |
| Corcuff, JB | 1 |
| Young, J | 2 |
| Masquefa-Giraud, P | 1 |
| Baudin, E | 2 |
| Daniel, E | 2 |
| Newell-Price, JD | 1 |
| Lourenço, R | 1 |
| Dias, P | 1 |
| Gouveia, R | 1 |
| Sousa, AB | 1 |
| Oliveira, G | 1 |
| Aylwin, S | 1 |
| Mustafa, O | 1 |
| Ball, S | 1 |
| Munir, A | 2 |
| Boelaert, K | 1 |
| Chortis, V | 1 |
| Cuthbertson, DJ | 1 |
| Daousi, C | 1 |
| Rajeev, SP | 1 |
| Davis, J | 1 |
| Cheer, K | 1 |
| Drake, W | 1 |
| Gunganah, K | 1 |
| Grossman, A | 2 |
| Gurnell, M | 2 |
| Powlson, AS | 1 |
| Karavitaki, N | 1 |
| Huguet, I | 1 |
| Kearney, T | 1 |
| Mohit, K | 1 |
| Meeran, K | 1 |
| Hill, N | 1 |
| Rees, A | 1 |
| Lansdown, AJ | 1 |
| Minder, AE | 1 |
| de Witte, LD | 1 |
| Smits, RB | 1 |
| Bartel, M | 1 |
| Kleijweg, M | 1 |
| Valk, GD | 1 |
| Vinkers, CH | 1 |
| Vergeer, M | 1 |
| Halioui-Louhaichi, S | 2 |
| Dridi, Y | 1 |
| Azzabi, O | 2 |
| Selmi, I | 1 |
| Fetni, I | 1 |
| Siala, N | 1 |
| Maherzi, A | 2 |
| Alexandraki, KI | 1 |
| Grossman, AB | 5 |
| Stigliano, A | 2 |
| Toscano, V | 2 |
| Cerquetti, L | 1 |
| Zieleniewski, W | 1 |
| Michalak, R | 1 |
| Jain, SH | 1 |
| Sadow, PM | 1 |
| Nosé, V | 1 |
| Dluhy, RG | 1 |
| Cohade, C | 1 |
| Broussaud, S | 1 |
| Louiset, E | 1 |
| Bennet, A | 1 |
| Huyghe, E | 1 |
| Caron, P | 1 |
| Goñi Iriarte, MJ | 1 |
| Hotham, NJ | 1 |
| Ilett, KF | 1 |
| Hackett, LP | 1 |
| Morton, MR | 1 |
| Muller, P | 1 |
| Hague, WM | 1 |
| Mangan, JK | 1 |
| Russell, JE | 1 |
| Vong, CH | 1 |
| Forest, M | 1 |
| Nicolino, M | 1 |
| Schteingart, DE | 6 |
| Akaza, I | 1 |
| Yoshimoto, T | 1 |
| Tsuchiya, K | 1 |
| Hirata, Y | 3 |
| de Herder, WW | 2 |
| Owen, LJ | 2 |
| Halsall, DJ | 2 |
| Keevil, BG | 2 |
| Kamenický, P | 1 |
| Droumaguet, C | 1 |
| Salenave, S | 1 |
| Blanchard, A | 1 |
| Jublanc, C | 1 |
| Gautier, JF | 2 |
| Brailly-Tabard, S | 1 |
| Leboulleux, S | 1 |
| Schlumberger, M | 1 |
| Monaghan, PJ | 1 |
| Brabant, G | 1 |
| Darby, D | 1 |
| Schiemer, R | 1 |
| Latibeaudiere, M | 1 |
| Close, C | 1 |
| Fox, R | 1 |
| Yoshida, M | 1 |
| Umeda, H | 1 |
| Iwama, S | 1 |
| Nakayama, S | 1 |
| Miyata, M | 1 |
| Ogawa, K | 1 |
| Maeda, H | 1 |
| Oiso, Y | 2 |
| Achong, N | 1 |
| D'Emden, M | 1 |
| Fagermo, N | 1 |
| Mortimer, R | 1 |
| Carroll, BJ | 1 |
| Iranmanesh, A | 1 |
| Keenan, DM | 1 |
| Cassidy, F | 1 |
| Wilson, WH | 1 |
| Veldhuis, JD | 1 |
| Biller, BM | 2 |
| Crespo, I | 1 |
| Gich, I | 1 |
| Rodríguez, J | 1 |
| Lim, WH | 1 |
| Torpy, DJ | 1 |
| Jeffries, WS | 1 |
| Shaw, JA | 1 |
| Pearson, DW | 1 |
| Krukowski, ZH | 1 |
| Fisher, PM | 1 |
| Bevan, JS | 2 |
| Lubin, V | 1 |
| Antoine, JM | 1 |
| Beressi, JP | 1 |
| Vexiau, P | 1 |
| DE MARTINIS, C | 1 |
| PUPITA, F | 1 |
| WEBER, J | 1 |
| DITZEL, J | 2 |
| DANIELS, H | 1 |
| SCHOPMAN, W | 1 |
| GOTH, E | 1 |
| POLLAK, L | 1 |
| KOSEKI, A | 1 |
| SHINOHARA, M | 1 |
| MURAYAMA, K | 1 |
| TAKANO, J | 1 |
| TSUNOKAKE, H | 1 |
| MITSUBE, K | 1 |
| PARIS, J | 1 |
| FAGLIA, G | 1 |
| D ALONZO, R | 1 |
| NORBIATO, G | 1 |
| ORTHMANN, G | 1 |
| LIUZZI, A | 1 |
| FERRARI, E | 1 |
| PIOTTI, LE | 1 |
| BOSCHERINI, B | 1 |
| FISCHETTI, M | 1 |
| MOLINATTI, GM | 2 |
| CAMANNI, F | 1 |
| MASSARA, F | 2 |
| MAGGIOLO, J | 1 |
| CASTIGLIONI, CA | 1 |
| OLIVIERI, E | 1 |
| LAMBERG, BA | 1 |
| LENTLE, BC | 1 |
| THOMAS, JP | 1 |
| DANOWSKI, TS | 2 |
| BONESSI, JV | 1 |
| SABEH, G | 1 |
| SUTTON, RD | 1 |
| WEBSTER, MW | 1 |
| SARVER, ME | 1 |
| WILLIAMSON, CI | 1 |
| BAKER, OA | 1 |
| BEETHAM, WP | 1 |
| IORI, E | 1 |
| SOLA, OH | 1 |
| VILANOVA, D | 1 |
| HOFFMAN, C | 1 |
| KOSANIK, M | 1 |
| WAINER, AC | 1 |
| SOBOTA, JT | 1 |
| REED, RJ | 1 |
| SUMMERS, VK | 1 |
| SHEEHAN, HL | 1 |
| HIPKIN, LJ | 1 |
| DAVIS, JC | 1 |
| TAMM, J | 1 |
| KUMAGAI, H | 1 |
| JANCHES, M | 1 |
| GOLDBERG, V | 1 |
| JAIMOVICH, L | 1 |
| CATOGGIO, P | 1 |
| DELABALZE, FA | 1 |
| SULLIVAN, WA | 1 |
| HYDROVITZ, JD | 1 |
| ROSOMOFF, H | 1 |
| MCCULLAGH, EP | 1 |
| FELDSTEIN, MA | 1 |
| TWEED, DC | 1 |
| DOHN, DF | 1 |
| ROBEL, P | 1 |
| Morris, DG | 1 |
| Kawashima, T | 1 |
| Oda, M | 1 |
| Kuno, T | 1 |
| Ueki, H | 1 |
| Yamada, S | 2 |
| Hisatomi, A | 1 |
| Nefzi, L | 1 |
| Ben Hariz, M | 1 |
| Ben Mrad, N | 1 |
| Ben Ammar, B | 1 |
| Hagendorf, A | 1 |
| Koper, JW | 1 |
| Brinkmann, AO | 1 |
| Lamberts, SW | 6 |
| Mizuki, K | 1 |
| Nawata, H | 1 |
| Greening, JE | 1 |
| Brain, CE | 1 |
| Perry, LA | 1 |
| Mushtaq, I | 1 |
| Sales Marques, J | 1 |
| Savage, MO | 1 |
| Blanco, C | 1 |
| Maqueda, E | 1 |
| Rubio, JA | 1 |
| Rodriguez, A | 1 |
| Nishikawa, T | 2 |
| Saito, J | 2 |
| Omura, M | 1 |
| Dang, CN | 1 |
| Trainer, P | 2 |
| Myhill, PC | 1 |
| Sillars, BA | 1 |
| Starkstein, S | 1 |
| Annus, T | 1 |
| Yeap, BB | 1 |
| Stewart, PM | 1 |
| Melmed, S | 1 |
| Bertagna, X | 1 |
| Buchfelder, M | 1 |
| Hermus, AR | 2 |
| Klibanski, A | 1 |
| Lacroix, A | 1 |
| Lindsay, JR | 1 |
| Petersenn, S | 1 |
| Sonino, N | 1 |
| Stalla, GK | 1 |
| Swearingen, B | 1 |
| Vance, ML | 1 |
| Wass, JA | 3 |
| Gillis, D | 1 |
| Rösler, A | 1 |
| Hannon, TS | 1 |
| Koplewitz, BZ | 1 |
| Hirsch, HJ | 1 |
| Hartog, M | 2 |
| Joplin, GF | 6 |
| Fotherby, K | 1 |
| Mattingly, D | 1 |
| Fraser, TR | 2 |
| Streeten, DH | 1 |
| Anderson, GH | 1 |
| Dalakos, TG | 1 |
| Seeley, D | 1 |
| Mallov, JS | 1 |
| Eusebio, R | 1 |
| Sunderlin, FS | 1 |
| Badawy, SZ | 1 |
| King, RB | 1 |
| Gogel, EL | 1 |
| Salber, PR | 1 |
| Tyrrell, JB | 1 |
| Rosenblum, ML | 1 |
| Findling, JW | 2 |
| Howanitz, PJ | 1 |
| Howanitz, JH | 1 |
| de Pinho, MO | 1 |
| Antunes, RC | 1 |
| Lima, MB | 1 |
| Francalanci, CC | 1 |
| Franco, S | 1 |
| Glaser, B | 1 |
| Kahana, L | 1 |
| Elias, V | 1 |
| Sheinfeld, M | 1 |
| Dal Bo Zanon, R | 1 |
| Fornasiero, L | 1 |
| Ruffato, G | 1 |
| Luzzato, G | 1 |
| Fabris, F | 1 |
| Girolami, A | 1 |
| Carey, RM | 3 |
| Tsao, HS | 1 |
| McKenzie, AK | 1 |
| Marcus, FS | 1 |
| Friedman, MA | 1 |
| Callen, PW | 1 |
| Churg, A | 1 |
| Harbour, J | 1 |
| de Quijada, M | 1 |
| Visser, TJ | 1 |
| Liddle, GW | 5 |
| Hsu, TH | 1 |
| Gann, DS | 1 |
| Tsan, KW | 2 |
| Russell, RP | 1 |
| Bertagna, C | 1 |
| Orth, DN | 11 |
| Beardwell, CG | 3 |
| Adamson, AR | 1 |
| Shalet, SM | 2 |
| Bergstrand, CG | 1 |
| Nilsson, KO | 1 |
| Wetterberg, L | 1 |
| Hiramatsu, R | 1 |
| Shimada, T | 1 |
| Sato, T | 2 |
| Nomura, K | 2 |
| Demura, H | 6 |
| Imaki, T | 1 |
| Miyagawa, M | 1 |
| Ono, M | 1 |
| Yano, T | 1 |
| Shizume, K | 2 |
| Bouallouche, A | 1 |
| Vermeulen, C | 1 |
| Brerault, JL | 1 |
| Fiet, J | 1 |
| Julien, R | 1 |
| Guillevin, L | 1 |
| Abou-Samra, AB | 1 |
| Fevre-Montange, M | 1 |
| Pugeat, M | 1 |
| Dechaud, H | 1 |
| Chalendar, D | 1 |
| Estour, B | 1 |
| Tourniaire, J | 1 |
| Jenkins, RM | 1 |
| Page, MM | 1 |
| Sindler, BH | 1 |
| Griffing, GT | 1 |
| Melby, JC | 3 |
| Herrlinger, JD | 1 |
| Euler, HH | 1 |
| Kleine, L | 1 |
| Kirmse, L | 1 |
| Müller-Hermelink, HK | 1 |
| Löffler, H | 1 |
| Robien, W | 1 |
| Zolle, I | 1 |
| Krieger, DT | 2 |
| Gormley, MJ | 1 |
| Hadden, DR | 1 |
| Kennedy, TL | 1 |
| Montgomery, DA | 2 |
| Murnaghan, GA | 1 |
| Sheridan, B | 2 |
| Zgliczyński, S | 1 |
| Bricaire, H | 3 |
| Luton, JP | 5 |
| Cassar, J | 2 |
| Loizou, S | 2 |
| Kelly, WF | 2 |
| Mashiter, K | 2 |
| Borretta, G | 1 |
| Alì, A | 1 |
| Cesario, F | 1 |
| Magro, G | 1 |
| Boccuzzi, A | 1 |
| Reimondo, G | 1 |
| Angeli, A | 2 |
| Miller, JW | 1 |
| Crapo, L | 1 |
| Freeman, DA | 1 |
| Miura, K | 7 |
| Myers, NC | 1 |
| Bruyette, DS | 1 |
| Minamori, Y | 1 |
| Yasuda, K | 2 |
| Murayama, M | 2 |
| Morita, H | 2 |
| Yamakita, N | 2 |
| Engelhardt, D | 2 |
| Avgerinos, PC | 2 |
| Yanovski, JA | 1 |
| Oldfield, EH | 2 |
| Cutler, GB | 2 |
| Weber, MM | 1 |
| Gaitan, D | 1 |
| Loosen, PT | 1 |
| Gibson, S | 1 |
| Crosby, SR | 1 |
| Stewart, MF | 1 |
| Jennings, AM | 1 |
| McCall, E | 1 |
| White, A | 2 |
| Kodama, C | 1 |
| Nakada, T | 1 |
| Sasagawa, I | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Metabolic, Pressor and Neuropsychological Effects of Metyrapone Treatment in Patients With Hypercortisolism[NCT05255900] | 20 participants (Anticipated) | Observational | 2022-04-28 | Recruiting | |||
| Activity of Abiraterone Acetate in the Management of Cushing's Syndrome in Patients With Adrenocortical Carcinoma[NCT03145285] | Phase 2 | 10 participants (Anticipated) | Interventional | 2017-04-18 | Active, not recruiting | ||
| Treatment of Pituitary Cushing Disease With a Selective CDK Inhibitor, R-roscovitine[NCT02160730] | Phase 2 | 4 participants (Actual) | Interventional | 2014-05-31 | Terminated (stopped due to NIH grant ended.) | ||
| An Open-label Study of the Efficacy and Safety of CORLUX (Mifepristone) in the Treatment of the Signs and Symptoms of Endogenous Cushing's Syndrome[NCT00569582] | Phase 3 | 50 participants (Actual) | Interventional | 2007-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The number of participants that achieved a urinary free cortisol level above the upper limit of the normal range but reduced by ≥50% from baseline at week 4. (NCT02160730)
Timeframe: Baseline, Week 4
| Intervention | Participants (Count of Participants) |
|---|---|
| R-roscovitine | 2 |
A visible change in tumor size as determined by the investigator after reviewing MRI reports between baseline and 4 weeks of treatment. (NCT02160730)
Timeframe: Baseline, 4 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| R-roscovitine | 0 |
"To evaluate the efficacy of R-roscovitine 400 mg oral administration twice daily for 4 days every week for total of 4 weeks on normalizing 24 hour urinary free cortisol (24 h UFC) levels in CD patients. Normalizing is defined as having urine free cortisol levels within the normal range for that lab value." (NCT02160730)
Timeframe: Baseline, 4 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| R-roscovitine | 0 |
The number of participants that experience an adverse event between baseline and study end likely related to study drug as a measure of safety and tolerability. (NCT02160730)
Timeframe: Baseline, 4 weeks
| Intervention | Participants (Count of Participants) |
|---|---|
| R-roscovitine | 2 |
Change in typical Cushing's syndrome clinical signs and symptoms defined by mean weight at baseline and 4 weeks. (NCT02160730)
Timeframe: Baseline, 4 weeks
| Intervention | lbs (Mean) | |
|---|---|---|
| Baseline | 4 Weeks | |
| R-roscovitine | 217 | 217.4 |
Mean diastolic blood pressure between baseline and 4 weeks. (NCT02160730)
Timeframe: Baseline, 4 weeks
| Intervention | mmHg (Mean) | |
|---|---|---|
| Baseline | 4 Weeks | |
| R-roscovitine | 76.5 | 71 |
HbA1c levels are measured at baseline and at study end, these are averaged across all subjects. (NCT02160730)
Timeframe: Baseline, 4 Weeks
| Intervention | Percentage (Mean) | |
|---|---|---|
| Baseline | Study End-4 weeks | |
| R-roscovitine | 6.9 | 7 |
Mean change in systolic blood pressure between baseline and 4 weeks. (NCT02160730)
Timeframe: Baseline, 4 weeks
| Intervention | mmHg (Mean) | |
|---|---|---|
| Baseline | 4 weeks | |
| R-roscovitine | 150.3 | 128.3 |
Mean serum cortisol values at baseline and 4 weeks (NCT02160730)
Timeframe: Baseline, 4 weeks
| Intervention | mg/dL (Mean) | |
|---|---|---|
| Baseline | 4 Weeks | |
| R-roscovitine | 25.6 | 27.1 |
Mean change between baseline and week 4 of fasting blood glucose levels. (NCT02160730)
Timeframe: Baseline, 4 Weeks
| Intervention | g/dL (Mean) | |
|---|---|---|
| Baseline | 4 weeks | |
| R-roscovitine | 121.4 | 104.3 |
Mean change in Plasma ACTH between baseline and 4 weeks. (NCT02160730)
Timeframe: Baseline, 4 weeks
| Intervention | pg/mL (Mean) | |
|---|---|---|
| Baseline | 4 weeks | |
| R-roscovitine | 79.3 | 79.9 |
Responder is defined as subject with a decrease greater than or equal to 5mm Hg in diastolic blood pressure from baseline to week 24 or last visit. (NCT00569582)
Timeframe: Baseline to Week 24
| Intervention | participants (Number) |
|---|---|
| Mifepristone | 8 |
Responder is defined as subject with a decrease greater than or equal to 25% in area under the curve for glucose on 2-hour oral glucose test from baseline to week 24 or last visit, for Cushing's patients with type-2 diabetes mellitus/impaired glucose tolerance. (NCT00569582)
Timeframe: Baseline to Week 24
| Intervention | participants (Number) |
|---|---|
| Mifepristone | 15 |
56 reviews available for metyrapone and Cushing's Syndrome
| Article | Year |
|---|---|
Cushing's disease: adrenal steroidogenesis inhibitors.
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Female; Humans; Hypokalemia; Ketoconazole; Male; Mety | 2022 |
What is the role of medical therapy in adrenal-dependent Cushing's syndrome?
Topics: Adrenal Gland Diseases; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Mitotane; Pituitary ACTH | 2020 |
Adrenally Directed Medical Therapies for Cushing Syndrome.
Topics: Adrenal Glands; Cushing Syndrome; Etomidate; Humans; Imidazoles; Ketoconazole; Metyrapone; Mitotane; | 2021 |
Pneumocystis pneumonia can complicate medical treatment of hypercortisolism even in outpatients with Cushing's disease.
Topics: ACTH Syndrome, Ectopic; Adult; Aged; Aged, 80 and over; Cushing Syndrome; Humans; Immunologic Defici | 2020 |
Medical therapy in severe hypercortisolism.
Topics: Cabergoline; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Mitotane | 2021 |
Updates in adrenal steroidogenesis inhibitors for Cushing's syndrome - A practical guide.
Topics: Cushing Syndrome; Cytochrome P-450 CYP11B2; Enzyme Inhibitors; Etomidate; Humans; Hydrocortisone; Im | 2021 |
Therapy of endocrine disease: steroidogenesis enzyme inhibitors in Cushing's syndrome.
Topics: Cushing Syndrome; Etomidate; Humans; Imidazoles; Ketoconazole; Metyrapone; Mitotane; Pyridines; Ster | 2015 |
Therapeutic Strategies for the Treatment of Severe Cushing's Syndrome.
Topics: Animals; Cushing Syndrome; Etomidate; Humans; Hydrocortisone; Ketoconazole; Metyrapone | 2016 |
Ectopic Cushing's syndrome due to a pheochromocytoma: a new case in the post-partum and review of literature.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cushing Syndrome; Female; Humans; Insulin; Metyrapone | 2009 |
[Cushing's syndrome: special issues].
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adult; Child; Cush | 2009 |
Drugs in the medical treatment of Cushing's syndrome.
Topics: Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Antiparkinson Agents; Cabergoline; Cushing Sy | 2009 |
Management of diabetes mellitus in Cushing's syndrome.
Topics: Cushing Syndrome; Diabetes Mellitus; Enzyme Inhibitors; Humans; Hypoglycemic Agents; Insulin Resista | 2010 |
Medical treatment of Cushing's syndrome: adrenal-blocking drugs and ketaconazole.
Topics: Cushing Syndrome; Enzyme Inhibitors; Etomidate; Humans; Ketoconazole; Metyrapone; Mitotane | 2010 |
Pregnancy-induced Cushing's syndrome in recurrent pregnancies: case report and literature review.
Topics: Adrenocorticotropic Hormone; Adult; Australia; Cushing Syndrome; Enzyme Inhibitors; Female; Humans; | 2012 |
Advances in medical therapies for Cushing's syndrome.
Topics: Animals; Bexarotene; Cushing Syndrome; Etomidate; Humans; Ketoconazole; Lapatinib; Metyrapone; Mifep | 2012 |
The medical management of Cushing's syndrome during pregnancy.
Topics: Adrenalectomy; Cushing Syndrome; Female; Humans; Hydrocortisone; Ketoconazole; Metyrapone; Pre-Eclam | 2013 |
[Cushing's syndrome during pregnancy].
Topics: Adrenal Cortex Neoplasms; Adult; Anti-Inflammatory Agents; Antimetabolites; Cushing Syndrome; Dexame | 2002 |
ON THE DIAGNOSIS OF ADDISON'S DISEASE AND CUSHING'S SYNDROME BY LABORATORY METHODS.
Topics: 17-Ketosteroids; Addison Disease; Adrenal Insufficiency; Adrenocorticotropic Hormone; Biochemical Ph | 1964 |
[METHODOLOGICAL DATA ON THE DYNAMIC EVALUATION OF THE DIENCEPHALON-ANTERIOR PITUITARY-ADRENAL CORTEX SYSTEM].
Topics: Acromegaly; Addison Disease; Adrenal Cortex; Adrenocorticotropic Hormone; Cushing Syndrome; Dexameth | 1964 |
Dynamic tests in the diagnosis and differential diagnosis of Cushing's syndrome.
Topics: Adrenal Cortex Function Tests; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethasone; Dia | 2003 |
[Urinary tetrahydro-11-deoxycortisol (THS)].
Topics: Addison Disease; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Biomarkers; Chromatography, Pa | 2005 |
[Medical treatment for Cushing's syndrome].
Topics: Aminoglutethimide; Aromatase Inhibitors; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Steroid | 2008 |
Treatment of adrenocorticotropin-dependent Cushing's syndrome: a consensus statement.
Topics: ACTH Syndrome, Ectopic; Adrenal Insufficiency; Adrenalectomy; Adrenocorticotropic Hormone; Cushing S | 2008 |
Normal and abnormal function of the hypothalamic-pituitary-adrenocortical system in man.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma, Chromophobe; Adolescent; Adrenocorticotropic Hormone | 1984 |
Hypercortisolism.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Corticotropin-Releasing Hormone; Cushing Syn | 1984 |
Treatment of Cushing's disease in children.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Bromocriptine; Child; Cushing Syndrom | 1982 |
The relationship between the pineal gland and the pituitary--adrenal axis in health, endocrine and psychiatric conditions.
Topics: Adenoma; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Circadian Rhythm; Cushing Syndr | 1983 |
[Cushing's syndrome: a diagnostic strategy].
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethas | 1984 |
Pathophysiology and treatment of Cushing's disease.
Topics: Adrenal Glands; Adrenalectomy; Aminoglutethimide; Cushing Syndrome; Delayed-Action Preparations; Hum | 1982 |
The medical treatment of Cushing's syndrome.
Topics: Adrenal Cortex Neoplasms; Adrenal Glands; Aminoglutethimide; Animals; Bromocriptine; Cushing Syndrom | 1993 |
[Non-invasive therapy of Cushing's syndrome].
Topics: Aminoglutethimide; Betamethasone; Bromocriptine; Clinical Trials as Topic; Cushing Syndrome; Cyprohe | 1994 |
Feline adrenocortical diseases: Part I--Hyperadrenocorticism.
Topics: Adrenocorticotropic Hormone; Animals; Cat Diseases; Cats; Cushing Syndrome; Dexamethasone; Diagnosis | 1994 |
Steroid biosynthesis inhibitors in Cushing's syndrome.
Topics: Adrenal Cortex Hormones; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate; Humans | 1994 |
Therapy of Cushing's syndrome with steroid biosynthesis inhibitors.
Topics: 3-Hydroxysteroid Dehydrogenases; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Etomidate | 1994 |
[Clinical usefulness of pharmacological treatment of Cushing's syndrome].
Topics: Administration, Oral; Aminoglutethimide; Cushing Syndrome; Dihydrotestosterone; Humans; Ketoconazole | 1994 |
[Cushing syndrome in children].
Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hor | 1993 |
[Metopiron test].
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Cushing Syndrome; Humans; Hypothalamo-Hypophyse | 1997 |
[Metyrapone test].
Topics: ACTH Syndrome, Ectopic; Adrenal Cortex Diseases; Adrenal Cortex Function Tests; Adrenal Insufficienc | 1997 |
The diagnosis and differential diagnosis of Cushing's syndrome and pseudo-Cushing's states.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Anti-Inflammatory Agents; Circadian Rhythm; Cor | 1998 |
[Diagnostic pitfalls in Cushing's disease].
Topics: Circadian Rhythm; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethasone; Diagnosis, Diffe | 2000 |
Recurrent ACTH-independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone.
Topics: Abortion, Therapeutic; Adolescent; Adrenal Glands; Cesarean Section; Cushing Syndrome; Female; Fetal | 2001 |
[Determination of serum (and urinary) 17-hydroxycorticosteroids and 17-ketosteroids].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adolescent; Adrenocorticotropic Hormone | 1976 |
Pathophysiology of Cushing's disease.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Cushing Syndrome; Gonadotropins, Pituitary; Gr | 1979 |
Topical steroids and hypothalamo-pituitary-adrenal suppression: a review.
Topics: Administration, Topical; Adrenal Cortex Hormones; Circadian Rhythm; Cushing Syndrome; Humans; Hypoth | 1978 |
[Drug therapy of pituitary tumors].
Topics: Bromocriptine; Cushing Syndrome; Cyproheptadine; Female; Humans; Male; Metyrapone; Octreotide; Pitui | 1991 |
The treatment of Cushing's syndrome.
Topics: Adrenalectomy; Cushing Syndrome; Humans; Metyrapone; Pituitary Gland | 1991 |
Appropriate laboratory testing in the screening and work-up of Cushing's syndrome.
Topics: Adenoma; Adrenocorticotropic Hormone; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethaso | 1988 |
Disorders of the hypothalamic-pituitary-adrenal axis.
Topics: Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adrenal Hyperplasia, Congenital; Adrenal Insuffic | 1985 |
Is it possible to diagnose pituitary-dependent Cushing's disease?
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hor | 1985 |
Cushing's syndrome: update of diagnosis and management.
Topics: Adenoma; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushin | 1986 |
Cushing's syndrome.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Alcoho | 1985 |
Primary adrenocortical nodular dysplasia, a distinct subtype of Cushing's syndrome. Case report and review of the literature.
Topics: Adolescent; Adrenal Cortex; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenocortical Hyperfunc | 1986 |
[New endocrine disorders attracting current interest--adrenal system].
Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Ho | 1969 |
[ACTH--how to read its figures].
Topics: Addison Disease; Adrenocorticotropic Hormone; Biological Assay; Blood Chemical Analysis; Circadian R | 1971 |
[Circadian rhythm of the hypothalamo-pituitary-adrenal system].
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Circ | 1972 |
[Aspect of hormones and hypertension].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Catechol | 1969 |
9 trials available for metyrapone and Cushing's Syndrome
| Article | Year |
|---|---|
Comparison of serum cortisol measurement by immunoassay and liquid chromatography-tandem mass spectrometry in patients receiving the 11β-hydroxylase inhibitor metyrapone.
Topics: Chromatography, Liquid; Cushing Syndrome; Diagnostic Techniques and Procedures; Drug Monitoring; Fal | 2011 |
[Changes in plasma level of corticotropin after intravenous injection of metyrapone. Value of this test in pituitary pathology].
Topics: Adrenocorticotropic Hormone; Adult; Clinical Trials as Topic; Cushing Syndrome; Drug Tolerance; Huma | 1977 |
ACTH and cortisol response to bromocriptine, and results of long-term therapy, in Cushing's disease.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Adult; Bromocriptine; Clinical Trials as Topic; C | 1978 |
Treatment of major depression with steroid suppressive drugs.
Topics: Adrenocortical Hyperfunction; Adult; Aged; Aminoglutethimide; Cushing Syndrome; Depressive Disorder; | 1991 |
Dual and selective actions of glucocorticoids upon basal and stimulated growth hormone release in man.
Topics: Adult; Arginine; Clonidine; Cushing Syndrome; Dexamethasone; Female; Growth Hormone; Growth Hormone- | 1990 |
Long-term follow-up of low-dose external pituitary irradiation for Cushing's disease.
Topics: Adolescent; Adrenalectomy; Adult; Aged; Child; Cushing Syndrome; Female; Follow-Up Studies; Humans; | 1990 |
Aminoglutethimide and metyrapone in the management of Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adolescent; Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Clinical Tria | 1985 |
The effect of metyrapone on aldosterone secretion in man.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Body We | 1967 |
Experience with a rapid oral metyrapone test and the plasma ACTH content in determining the cause of Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gla | 1969 |
324 other studies available for metyrapone and Cushing's Syndrome
| Article | Year |
|---|---|
Cushing's syndrome: development of highly potent and selective CYP11B1 inhibitors of the (pyridylmethyl)pyridine type.
Topics: Animals; Cell Line; Cricetinae; Cushing Syndrome; Cytochrome P-450 CYP11B2; Humans; Liver; Models, M | 2013 |
Ketoconazole- and Metyrapone-Induced Reductions on Urinary Steroid Metabolites Alter the Urinary Free Cortisol Immunoassay Reliability in Cushing Syndrome.
Topics: Cushing Syndrome; Humans; Hydrocortisone; Immunoassay; Ketoconazole; Metyrapone; Reproducibility of | 2022 |
Differences in the spectrum of steroidogenic enzyme inhibition between Osilodrostat and Metyrapone in ACTH-dependent Cushing syndrome patients.
Topics: Adrenocorticotropic Hormone; Androstenedione; Chromatography, Liquid; Cortodoxone; Cushing Syndrome; | 2022 |
Cushing syndrome as a failed cardiac screen in a patient with McCune-Albright syndrome: a case report.
Topics: Cushing Syndrome; Dexamethasone; Fibrous Dysplasia, Polyostotic; GTP-Binding Protein alpha Subunits; | 2022 |
Pneumocystis pneumonia in patients with Cushing's syndrome: A French multicenter retrospective study.
Topics: Cushing Syndrome; Humans; Hydrocortisone; Metyrapone; Pneumonia, Pneumocystis; Retrospective Studies | 2023 |
LC-MS/MS method for simultaneous quantification of osilodrostat and metyrapone in human plasma from patients treated for Cushing's Syndrome.
Topics: Chromatography, Liquid; Cushing Syndrome; Humans; Metyrapone; Tandem Mass Spectrometry | 2023 |
ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of Cushing's syndrome.
Topics: 14-alpha Demethylase Inhibitors; ACTH-Secreting Pituitary Adenoma; Adenoma; Coronavirus Infections; | 2020 |
Practical Considerations for the Management of Cushing's Disease and COVID-19: A Case Report.
Topics: Aged; Anti-Inflammatory Agents; Antimetabolites; Betacoronavirus; Coronavirus Infections; COVID-19; | 2020 |
Approach to the Patient Treated with Steroidogenesis Inhibitors.
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Enzyme Inhibitors; Female; Humans; Imidazoles; | 2021 |
A polymorphism in the CYP17A1 gene influences the therapeutic response to steroidogenesis inhibitors in Cushing's syndrome.
Topics: Adult; Cushing Syndrome; Female; Humans; Ketoconazole; Male; Metyrapone; Middle Aged; Pharmacogeneti | 2017 |
Cyclical Cushing's: how best to catch the ups and downs.
Topics: Adrenalectomy; Aged; Cushing Syndrome; Humans; Hydrocortisone; Male; Metyrapone; Treatment Outcome | 2017 |
Adding metyrapone to chemotherapy plus mitotane for Cushing's syndrome due to advanced adrenocortical carcinoma.
Topics: Adrenal Cortex Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Antimetabolites, Antineoplastic; An | 2018 |
Preoperative medical treatment in Cushing's syndrome: frequency of use and its impact on postoperative assessment: data from ERCUSYN.
Topics: Adrenal Glands; Adult; Aged; Cushing Syndrome; Databases, Factual; Europe; Female; Humans; Ketoconaz | 2018 |
Unexpected adverse effect of metyrapone: A case report.
Topics: Adult; Cushing Syndrome; Humans; Male; Metyrapone | 2018 |
Behaviour disorder caused by Cushing's syndrome in an older person.
Topics: Aged, 80 and over; Antipsychotic Agents; Cushing Syndrome; Diagnosis, Differential; Enzyme Inhibitor | 2018 |
Metyrapone treatment in Cushing's syndrome: a real-life study.
Topics: Adult; Aged; Circadian Rhythm; Cushing Syndrome; Enzyme Inhibitors; Female; Humans; Hydrocortisone; | 2018 |
Should we avoid using ketoconazole in patients with severe Cushing’s syndrome and increased levels of liver enzymes?
Topics: Adult; Cushing Syndrome; Drug Therapy, Combination; Enzyme Inhibitors; Female; Humans; Ketoconazole; | 2018 |
Hypokalaemic metabolic alkalosis, hypertension and diabetes: what is the link.
Topics: Alkalosis; Cushing Syndrome; Diabetes Mellitus; Female; Humans; Hypertension; Hypokalemia; Metyrapon | 2019 |
Osilodrostat Is a Potential Novel Steroidogenesis Inhibitor for the Treatment of Cushing Syndrome: An In Vitro Study.
Topics: Aldosterone; Cell Culture Techniques; Cortodoxone; Cushing Syndrome; Cytochrome P-450 CYP11B2; Enzym | 2019 |
[A case of acute respiratory distress syndrome caused by cryptococcus and cytomegalovirus co-infection after Cushing's syndrome treatment].
Topics: Aged, 80 and over; Coinfection; Cryptococcosis; Cushing Syndrome; Cytomegalovirus Infections; Female | 2013 |
Case report: Beneficial effect of 11β-hydroxylase inhibitor in the management of an elderly patient with an androgen-producing inoperable adrenal tumor.
Topics: Adrenal Gland Neoplasms; Aged, 80 and over; Androgens; Cushing Syndrome; Dexamethasone; Enzyme Inhib | 2013 |
Rapid control of severe neoplastic hypercortisolism with metyrapone and ketoconazole.
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Cushing Synd | 2015 |
Neonatal McCune-Albright syndrome with systemic involvement: a case report.
Topics: Cafe-au-Lait Spots; Cushing Syndrome; Diagnosis, Differential; Failure to Thrive; Fatal Outcome; Fem | 2015 |
Effectiveness of Metyrapone in Treating Cushing's Syndrome: A Retrospective Multicenter Study in 195 Patients.
Topics: ACTH-Secreting Pituitary Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschoo | 2015 |
Effectiveness of Metyrapone in Treating Cushing's Syndrome: A Retrospective Multicenter Study in 195 Patients.
Topics: ACTH-Secreting Pituitary Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschoo | 2015 |
Effectiveness of Metyrapone in Treating Cushing's Syndrome: A Retrospective Multicenter Study in 195 Patients.
Topics: ACTH-Secreting Pituitary Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschoo | 2015 |
Effectiveness of Metyrapone in Treating Cushing's Syndrome: A Retrospective Multicenter Study in 195 Patients.
Topics: ACTH-Secreting Pituitary Adenoma; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschoo | 2015 |
[Cushing's syndrome in a manic patient with a long-standing bipolar disorder: cause or coincidence?].
Topics: Aged; Bipolar Disorder; Cushing Syndrome; Diagnosis, Differential; Female; Humans; Metyrapone | 2015 |
[Recovery of Cushing syndrome revealing McCune-Albright syndrome].
Topics: Child; Cushing Syndrome; Enzyme Inhibitors; Female; Fibrous Dysplasia, Polyostotic; Follow-Up Studie | 2016 |
[Indications and future perspectives in the pharmacological treatment of hypercortisolism].
Topics: Adenoma; Cushing Syndrome; Humans; Hydrocortisone; Italy; Ketoconazole; Metyrapone; Pituitary Neopla | 2016 |
[Pharmacological treatment in adrenal Cushing's syndrome.]
Topics: Cushing Syndrome; Humans; Ketoconazole; Metyrapone | 2016 |
A successful case of pregnancy in a woman with ACTH-independent Cushing's syndrome treated with ketoconazole and metyrapone.
Topics: Adult; Cushing Syndrome; Drug Therapy, Combination; Female; Humans; Ketoconazole; Metyrapone; Pregna | 2017 |
A patient with ectopic cortisol production derived from malignant testicular masses.
Topics: Adrenal Rest Tumor; Adrenocortical Carcinoma; Adrenocorticotropic Hormone; Aged; Cushing Syndrome; H | 2008 |
Transfer of metyrapone and its metabolite, rac-metyrapol, into breast milk.
Topics: Adult; Area Under Curve; Breast Feeding; Chromatography, High Pressure Liquid; Cushing Syndrome; Enz | 2009 |
Profound neutropenia resulting from metyrapone-induced adrenal crisis.
Topics: Adrenal Insufficiency; Antimetabolites; Cushing Syndrome; Female; Humans; Metyrapone; Middle Aged; N | 2009 |
Ketoconazole treatment for Cushing syndrome in McCune-Albright syndrome.
Topics: Adrenergic Agents; Adrenocorticotropic Hormone; Aminoglutethimide; Antifungal Agents; Chemical and D | 2009 |
Endothelial dysfunction aassociated with hypercortisolism is reversible in Cushing's syndrome.
Topics: Adult; Aged; Blood Flow Velocity; Carotid Arteries; Cushing Syndrome; Endothelium, Vascular; Humans; | 2010 |
Cortisol measurement in patients receiving metyrapone therapy.
Topics: Chromatography, Liquid; Cushing Syndrome; Humans; Hydrocortisone; Immunoassay; Mass Spectrometry; Me | 2010 |
Mitotane, metyrapone, and ketoconazole combination therapy as an alternative to rescue adrenalectomy for severe ACTH-dependent Cushing's syndrome.
Topics: Adolescent; Adult; Aged; Antimetabolites; Antineoplastic Agents; Cushing Syndrome; Drug Therapy, Com | 2011 |
Type 2 diabetes identified in pregnancy secondary to Cushing's syndrome.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Cushing Syndrome; Diabetes Mellitus, Type 2 | 2011 |
Assessment of long-term efficacy and safety of metyrapone monotherapy in a patient with ACTH-independent macronodular adrenal hyperplasia.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aged; Cushing Syndrome; Dose-Response Relationship, Dru | 2012 |
Pathophysiology of hypercortisolism in depression: pituitary and adrenal responses to low glucocorticoid feedback.
Topics: Adrenocorticotropic Hormone; Adult; Case-Control Studies; Cushing Syndrome; Depressive Disorder, Maj | 2012 |
Comparison of serum cortisol measurement by immunoassay and liquid chromatography-tandem mass spectrometry in patients receiving the 11β-hydroxylase inhibitor metyrapone.
Topics: Cushing Syndrome; Drug Monitoring; Humans; Hydrocortisone; Metyrapone; Steroid 11-beta-Hydroxylase | 2012 |
A reappraisal of the medical therapy with steroidogenesis inhibitors in Cushing's syndrome.
Topics: Adolescent; Adult; Aged; Antimetabolites; Child; Cushing Syndrome; Female; Humans; Ketoconazole; Mal | 2012 |
Cushing's syndrome during pregnancy: curative adrenalectomy at 31 weeks gestation.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Cushing Syndrome; Female; Gestational A | 2002 |
[A new synthetic inhibitor of adrenal cortex hormones: 2-methyl-1,2-bis(3-pyridyl)-1-propanone (SU 4885, Metopirone)].
Topics: Adrenal Cortex Hormones; Cushing Syndrome; Humans; Liver Cirrhosis; Metyrapone; Pyridines | 1962 |
EFFECT OF LONG-TERM ADMINISTRATION OF METYRAPONE AND DEXAMETHASONE IN A PATIENT WITH CUSHING'S SYNDROME.
Topics: Cushing Syndrome; Dexamethasone; Humans; Metyrapone; Mineralocorticoid Receptor Antagonists | 1963 |
EFFECT OF METOPIRONE IN A PATIENT WITH ADRENAL CORTICAL CARCINOMA.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Cushing | 1963 |
[TESTING OF THE FUNCTION OF THE PITUITARY GLAND AND THE ADRENAL GLANDS WITH METOPIRONE].
Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; | 1963 |
[ENDOCRINOLOGICAL OBSERVATIONS ON CUSHING'S SYNDROME].
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocorticotropic Ho | 1963 |
[SIGNIFICANCE OF THE EVALUATION OF URINARY PREGNANTRIOL IN SOME ADRENAL ENDOCRINE DISORDERS: FINDINGS IN BASAL CONDITIONS AND AFTER TREATMENTS STIMULATING OR INHIBITING THE ADRENAL CORTEX].
Topics: Adolescent; Adrenal Cortex; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocortical Hyperfun | 1964 |
[THE METOPIRONE TEST IN THE DIFFERENTIAL DIAGNOSIS OF VARIOUS ENDOCRINE DISORDERS OF CHILDHOOD].
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Carbohydrate Metabolism; Child; Cu | 1963 |
[INDIRECT EVALUATION OF CORTICOTROPIN ACTIVITY IN VARIOUS SITUATIONS OF PITUITARY-ADRENAL PHYSIOPATHOLOGY].
Topics: Acromegaly; Adrenocorticotropic Hormone; Anorexia Nervosa; Cushing Syndrome; Dexamethasone; Humans; | 1964 |
[EXPLORATION OF THE ACTH HYPOPHYSEAL RESERVE WITH METOPIRONE IN DIFFERENT ENDOCRINOPATHIES].
Topics: 17-Ketosteroids; Acromegaly; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Clinical Lab | 1963 |
CUSHING'S SYNDROME CO-EXISTING WITH HYPERTHYROIDISM. REPORT OF A CASE AND SOME METABOLIC OBSERVATIONS.
Topics: Adrenal Cortex Hormones; Adrenalectomy; Adrenocorticotropic Hormone; Blood Chemical Analysis; Choles | 1964 |
ADRENAL FUNCTION AND THE COMPLICATIONS OF DIABETES MELLITUS.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Blood Chemical Analysis; Carbon Isotopes; Cush | 1964 |
PROBABILITIES OF PITUITARY-ADRENAL RESPONSIVENESS AFTER STEROID THERAPY.
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Biomedical Research; Cushing Syndr | 1964 |
MEDICAL GRAND ROUNDS FROM THE UNIVERSITY OF ALABAMA MEDICAL CENTER.
Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethasone; Diagnosis, Differenti | 1964 |
[CONTRIBUTION TO THE FUNCTIONAL STUDY OF THE PITUITARY-ADRENAL AXIS WITH METHOPYRAPONE (2-METHYL-1,2-BIS(3-PYRIDYL)-1-PROPANONE)].
Topics: Adolescent; Adrenal Glands; Adrenocortical Hyperfunction; Child; Cushing Syndrome; Hirsutism; Humans | 1964 |
[ADRENAL CORTEX HYPERPLASIA ASSOCIATED WITH HYPERTROPHY OF THE THYMUS GLAND AND ACANTHOSIS NIGICANS IN A CHILD].
Topics: Acanthosis Nigricans; Adrenal Cortex; Adrenal Gland Diseases; Adrenocortical Hyperfunction; Adrenoco | 1964 |
MULTIPLE BRONCHIAL ADENOMAS, CUSHING'S SYNDROME AND HYPOKALEMIC ALKALOSIS. REPORT OF A CASE.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenalectomy; Adrenocorticotropic Hormone; Alk | 1964 |
DIFFERENTIAL DIAGNOSIS OF CUSHING'S SYNDROME AND OBESITY ASSOCIATED WITH STRIAE.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Betamethasone; Cushing Synd | 1964 |
[THE DIFFERENTIAL DIAGNOSIS OF CUSHING'S SYNDROME].
Topics: Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Cushing Syndrome | 1964 |
[STUDIES ON THE DIAGNOSTIC USE OF METOPIRONE (11-BETA-HYDROXYLASE INHIBITOR) IN DISEASES OF THE PITUITARY AND ADRENAL CORTEX].
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Blo | 1964 |
USE OF METHOPYRAPONE (SU-4885) IN THE STUDY OF PITUITARY-ADRENAL RESPONSE IN PATIENTS UNDER CORTICOSTEROID TREATMENT.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Cus | 1965 |
CUSHING'S SYNDROME FOLLOWING PARTIAL ADRENALECTOMY AND COMPLETE HYPOPHYSECTOMY.
Topics: 17-Ketosteroids; Adrenalectomy; Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethasone; Humans | 1965 |
A STUDY OF PITUITARY FUNCTION AFTER INTRASELLAR IMPLANTATION OF 90YTTRIUM.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acromegaly; Basal Metabolism; Breast Neoplasms; Cushing | 1965 |
CLINICAL ASSESSMENT OF THE PERORAL METOPIRONE TEST.
Topics: Adenoma; Adenoma, Chromophobe; Adrenalectomy; Adrenocorticotropic Hormone; Cushing Syndrome; Diabete | 1965 |
[Pituitary reactions to adrenalectomy for Cushing's syndrome and to the administration of SU 4885].
Topics: Adrenalectomy; Cushing Syndrome; Humans; Metyrapone; Pituitary Diseases; Pituitary Gland; Pyridines | 1961 |
Metyrapone for delirium due to Cushing's syndrome induced by occult ectopic adrenocorticotropic hormone secretion.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Cushing Syndrome; Delirium; Enzyme Inhibitors; | 2004 |
[Treatment with metyrapone of Cushing's syndrome revealing McCune-Albright syndrome].
Topics: Adrenal Hyperplasia, Congenital; Cushing Syndrome; Enzyme Inhibitors; Female; Fibrous Dysplasia, Pol | 2005 |
Expression of the human glucocorticoid receptor splice variants alpha, beta, and P in peripheral blood mononuclear leukocytes in healthy controls and in patients with hyper- and hypocortisolism.
Topics: Adult; Aged; Case-Control Studies; Cushing Syndrome; Female; Humans; Hydrocortisone; Leukocytes, Mon | 2005 |
Efficient short-term control of hypercortisolaemia by low-dose etomidate in severe paediatric Cushing's disease.
Topics: Adrenalectomy; Child; Contraindications; Cushing Syndrome; Etomidate; Humans; Hydrocortisone; Ketoco | 2005 |
Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cushing Syndrome; Enzyme Inhibitors; Female; | 2006 |
Pharmacological management of Cushing's syndrome: an update.
Topics: Cushing Syndrome; Dopamine Antagonists; Hormone Antagonists; Humans; Hypothalamo-Hypophyseal System; | 2007 |
Reduction in salivary cortisol concentration correlates with resolution of psychosis in Cushing's syndrome.
Topics: Antimetabolites; Cushing Syndrome; Humans; Hydrocortisone; Male; Metyrapone; Middle Aged; Psychotic | 2008 |
Prolonged remission of severe Cushing syndrome without adrenalectomy in an infant with McCune-Albright syndrome.
Topics: Adrenalectomy; Adrenergic Agents; Aminoglutethimide; Child; Cushing Syndrome; Enzyme Inhibitors; Fem | 2008 |
The assessment of patients with Cushing's syndrome before and after pituitary implantation.
Topics: 17-Ketosteroids; Cushing Syndrome; Dexamethasone; Humans; Metyrapone; Yttrium Isotopes | 1967 |
Cushing's disease in a patient with a 'nonfunctioning' pituitary tumor. Spontaneous development and remission.
Topics: Adenoma, Chromophobe; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushing Syndrome; Femal | 1983 |
Cushing's disease: clinical and laboratory response to bromocriptine therapy.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Bromocri | 1984 |
Sodium valproate and metyrapone for pituitary-dependent Cushing's disease.
Topics: Adrenal Glands; Adult; Cushing Syndrome; Drug Therapy, Combination; Female; Humans; Metyrapone; Pitu | 1984 |
Clotting changes in Cushing's syndrome: elevated factor VIII activity.
Topics: Adrenalectomy; Blood Coagulation; Blood Coagulation Tests; Cushing Syndrome; Factor VIII; Female; Hu | 1983 |
Suppression of ACTH by cortisol in dexamethasone-nonsuppressible Cushing's disease.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Depression, Chemica | 1980 |
Coexistence of pituitary adrenocorticotropin-dependent Cushing's syndrome with a solitary adrenal adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethasone; Fema | 1980 |
Twelve-hour cycles of adrenocorticotropin and cortisol secretion in Cushing's disease.
Topics: Adrenocorticotropic Hormone; Circadian Rhythm; Cushing Syndrome; Dexamethasone; Female; Humans; Hydr | 1980 |
Successful therapy of an ACTH-producing gastric carcinoid APUD tumor: report of a case and review of the literature.
Topics: Adrenocorticotropic Hormone; Apudoma; Carcinoid Tumor; Cushing Syndrome; Cytoplasmic Granules; Femal | 1980 |
Regulation of prolactin secretion in patients with Cushing's disease. A comparative study on the effects of dexamethasone, lysine vasopressin and ACTH on prolactin secretion by the rat pituitary gland in vitro.
Topics: Adrenocorticotropic Hormone; Adult; Animals; Cushing Syndrome; Dexamethasone; Dopamine; Female; Huma | 1981 |
The George M. Kober lecture. "Cushing's syndrome--1980.".
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethasone; Humans; Hydrocortisone; Metyrapone; Pi | 1980 |
Cyproheptadine in the control of Cushing's disease.
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Hydrocortisone | 1981 |
Clinical and laboratory findings and results of therapy in 58 patients with adrenocortical tumors admitted to a single medical center (1951 to 1978).
Topics: Adenoma; Adolescent; Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenocorticotropic Ho | 1981 |
Prolonged remission in florid Cushing's syndrome following metyrapone treatment.
Topics: Adrenocorticotropic Hormone; Aged; Cushing Syndrome; Female; Humans; Hydrocortisone; Male; Metyrapon | 1981 |
A case of dexamethasone non-suppressible Cushing's disease hardly differentiated from ectopic ACTH syndrome.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexamethasone; Diagnos | 1983 |
Concomitant falls of plasma cortisol and ACTH levels in a case of Cushing's disease during treatment with trilostane.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Aged; Cushing Syndrome; Dihydrotestosterone; | 1984 |
The value of beta-lipotrophin measurement during the short metyrapone test in patients with pituitary diseases and in Cushing's syndrome.
Topics: Adrenocorticotropic Hormone; Adult; beta-Lipotropin; Cortodoxone; Cushing Syndrome; Female; Humans; | 1984 |
Atypical case of alcohol-induced Cushingoid syndrome.
Topics: Alcoholism; Cushing Syndrome; Female; Humans; Metyrapone; Middle Aged | 1981 |
The superiority of the metyrapone test versus the high-dose dexamethasone test in the differential diagnosis of Cushing's syndrome.
Topics: Adolescent; Adrenal Cortex Neoplasms; Adult; Aged; Cortodoxone; Cushing Syndrome; Dexamethasone; Dia | 1983 |
[Successful conservative treatment of bronchial carcinoid with Cushing's syndrome due to ectopic ACTH production].
Topics: ACTH Syndrome, Ectopic; Bronchial Neoplasms; Carcinoid Tumor; Cushing Syndrome; Cyclophosphamide; Do | 1983 |
Synthesis of radioiodinated metyrapone--a potential adrenal imaging agent.
Topics: Adrenal Glands; Animals; Cushing Syndrome; Female; Humans; Iodine Radioisotopes; Isotope Labeling; M | 1983 |
Cushing's syndrome in pregnancy--treatment with metyrapone.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Cushing Syndrome; Female; Humans; Metyrapone; Pregnancy; Pr | 1982 |
[Cushing's syndrome: metyrapone therapy as a preparation for selective trans-sphenoidal adenomectomy].
Topics: Adenoma; Adolescent; Adult; Cushing Syndrome; Female; Humans; Male; Metyrapone; Middle Aged; Pituita | 1982 |
[Cushing's syndrome. Medical treatment of adrenal hypercorticism].
Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Androstanols; Bromocriptine; Cushing Syndrome; Cyprohept | 1980 |
Deoxycorticosterone and aldosterone excretion in Cushing's syndrome.
Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Carcinoma; | 1980 |
Misdiagnosis of Cushing's syndrome in a patient receiving rifampicin therapy for tuberculosis.
Topics: Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushing Syndrome; Diabetes Mell | 1995 |
Adrenal carcinoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dia | 1994 |
Effects of reserpine treatment on pituitary-adrenocortical axis in patients with Cushing's disease.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Circadian Rhythm; Cushing Syndrome; Depression, Chemic | 1993 |
The metyrapone and dexamethasone suppression tests for the differential diagnosis of the adrenocorticotropin-dependent Cushing syndrome: a comparison.
Topics: Adrenocorticotropic Hormone; Cortodoxone; Cushing Syndrome; Decision Trees; Dexamethasone; Diagnosis | 1994 |
The Cushing syndrome: quest for the Holy Grail.
Topics: Cushing Syndrome; Data Interpretation, Statistical; Dexamethasone; Humans; Metyrapone; Pituitary Fun | 1994 |
Two patients with Cushing's disease in a kindred with multiple endocrine neoplasia type I.
Topics: Adolescent; Adult; Cushing Syndrome; Depressive Disorder; Dexamethasone; Female; Humans; Hyperparath | 1993 |
Differential release of proopiomelanocortin-derived peptides from the human pituitary: evidence from a panel of two-site immunoradiometric assays.
Topics: Adrenocorticotropic Hormone; Adult; Aged; beta-Endorphin; beta-Lipotropin; Corticotropin-Releasing H | 1994 |
An unusual profile of endocrine study in a patient with pre-Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adrenoc | 1993 |
Stimulation by peptide histidine methionine (PHM) of adrenocorticotropin secretion in patients with Cushing's disease: a comparison with the effect of vasoactive intestinal peptide (VIP) and a study on the effect of combined administration of corticotropi
Topics: Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethasone | 1994 |
ACTH-independent Cushing's syndrome in pregnancy with spontaneous resolution after delivery: control of the hypercortisolism with metyrapone.
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Delivery, Obstetric; Female; Humans; Hydrocort | 1993 |
Corticotropin-releasing hormone, proopiomelanocortin, and glucocorticoid receptor gene expression in adrenocorticotropin-producing tumors in vitro.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Arginine | 1993 |
Familial adrenocorticotropin-independent Cushing's syndrome with bilateral macronodular adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormon | 1993 |
Elevated plasma 19-hydroxyandrostenedione levels in Cushing's disease: stimulation with ACTH and inhibition with metyrapone.
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Androstenedione; Blood Pressure; Cushin | 1993 |
Use of metyrapone to treat pituitary-dependent hyperadrenocorticism in a cat with large cutaneous wounds.
Topics: Adrenalectomy; Adrenocortical Hyperfunction; Animals; Cat Diseases; Cats; Combined Modality Therapy; | 1993 |
A comparison of the overnight and the standard metyrapone test for the differential diagnosis of adrenocorticotrophin-dependent Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Cortodoxone; Cushing Syndrome; Humans; Hydrocortisone; Metyrapone; Pilot Pro | 1996 |
Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adenoma; Adolescent; Adrenocorticotropic Hormone; Adult; Cortodoxone; Cushin | 1997 |
[Night suppression with high doses of dexamethasone and metyrapone tests for the etiological diagnosis of Cushing syndrome].
Topics: Adolescent; Adult; Cushing Syndrome; Dexamethasone; Female; Humans; Male; Metyrapone; Middle Aged | 1996 |
Postoperative metyrapone test in the early assessment of outcome of pituitary surgery for Cushing's disease.
Topics: Adolescent; Adult; Cortodoxone; Cushing Syndrome; Dexamethasone; Female; Glucocorticoids; Humans; Hy | 1997 |
Early assessment of outcome of pituitary surgery for Cushing's disease.
Topics: Cushing Syndrome; Humans; Hydrocortisone; Metyrapone; Pituitary Gland; Postoperative Period; Recurre | 1997 |
Probability in practice in the diagnosis of Cushing's syndrome.
Topics: Cushing Syndrome; Diagnosis, Differential; Humans; Metyrapone; Petrosal Sinus Sampling; Predictive V | 1997 |
Cushing's syndrome due to bilateral adrenocortical adenomas with different pathological features.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Adenoma; Adrenocorticotropic Hormone; Codon; | 1997 |
[Cushing's syndrome: clinical study of fifteen cases].
Topics: Adult; Aged; Cushing Syndrome; Dexamethasone; Female; Humans; Hydrocortisone; Ketoconazole; Male; Me | 1998 |
A case of Cushing's syndrome due to ACTH-independent bilateral macronodular hyperplasia associated with excessive secretion of mineralocorticoids.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aged; Aldosterone; Cushing Syndrome; Dexamethasone; Glu | 1998 |
Pregnancy-dependent Cushing's syndrome in three pregnancies.
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Female; Humans; Hydrocortisone; Metyrapone; Pr | 2000 |
Cost-effectiveness and accuracy of the tests used in the differential diagnosis of Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocorticotropi | 1999 |
Cushing's syndrome due to phaeochromocytoma secreting the precursors of adrenocorticotropin.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; alpha-MSH; Anti-Inflamma | 2000 |
Involvement of the cholinergic pathway in the pathogenesis of pituitary Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenocorticotropic Hormone; Atropine; Choline; | 2001 |
Rational, effective metyrapone treatment of ACTH-independent bilateral macronodular adrenocortical hyperplasia (AIMAH).
Topics: Adrenal Glands; Cushing Syndrome; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Humans; Hydrocortiso | 2001 |
The lethal form of Cushing's in 7B2 null mice is caused by multiple metabolic and hormonal abnormalities.
Topics: Adrenocorticotropic Hormone; Animals; Blood Glucose; Cause of Death; Corticosterone; Cushing Syndrom | 2002 |
Metyrapone for Cushing's syndrome.
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Enzyme Inhibitors; Humans; Hydrocortisone; Mal | 2002 |
Endocrine and metabolic diseases. Adrenal diseases.
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Insuffici | 1976 |
Hormone secretion in alcohol-induced pseudo-Cushing's syndrome. Differential diagnosis with Cushing disease.
Topics: Adult; Alanine Transaminase; Aspartate Aminotransferases; Cushing Syndrome; Dexamethasone; Diagnosis | 1979 |
Cyproheptadine in Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Function Tests; Adult; Bromocriptine; Cushing Syndrome; Cy | 1977 |
Pituitary function after removal of pituitary microadenomas in Cushing's disease.
Topics: 17-Ketosteroids; Adenoma; Adult; Cushing Syndrome; Follicle Stimulating Hormone; Humans; Hydrocortis | 1978 |
Studies of ACTH secretion control in 116 cases of Cushing's syndrome.
Topics: Adrenal Gland Diseases; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Biological Assay; Cushi | 1975 |
[Adrenal cortex function tests].
Topics: Addison Disease; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Cushing Syndrome; Dexam | 1975 |
ACTH-secreting 'apudoma' of gallbladder.
Topics: Adenocarcinoma; Adrenocorticotropic Hormone; Adult; Autopsy; Cushing Syndrome; Dexamethasone; Diagno | 1975 |
[Paradoxical response of adrenal glands to dexamethasone in a case of adrenal carcinoma].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotr | 1975 |
The diagnostic value of hypothalamic-pituitary-adrenocortical function tests in patients with Cushing's syndrome.
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Function Tests; Adrenal Gland Neoplasms; Adrenocorticotr | 1975 |
Gastric carcinoid with ectopic production of ACTH and beta-MSH.
Topics: Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Carcinoma, Squamous Cell; Cushing Syndro | 1976 |
Drug controlled of Cushing's syndrome. Combined aminoglutethimide and metyrapone therapy.
Topics: Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Dexamethasone; Drug Evaluation; Dr | 1976 |
[Diagnostic problems in Cushing's syndrome during pregnancy].
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Female; Humans; Hydrocortisone; Metyrapone; Pr | 1976 |
Medullary thyroid carcinoma: ectopic production of peptides with ACTH-like, corticotrophin releasing factor-like and prolactin production-stimulating activities.
Topics: Adrenocorticotropic Hormone; Antigens; Biological Assay; Calcitonin; Carcinoma; Corticotropin-Releas | 1976 |
Periodic remission in Cushing's disease with paradoxical dexamethasone response: an expression of periodic hormonogenesis.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Cosyntropin; Cushing | 1976 |
Ectopic ACTH syndrome due to salivary gland adenoid cystic carcinoma.
Topics: Adrenocorticotropic Hormone; Aged; Autopsy; Carcinoma, Adenoid Cystic; Cushing Syndrome; Female; Hor | 1977 |
[ACTH secretion and adrenocortical responsiveness in Cushing's syndrome due to adrenocortical hyperplasia (author's transl)].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Cortex; Adrenal Glands; Adrenalectomy; Adrenocortical | 1976 |
Assessment of 11beta-hydroxylase activity with plasma corticosterone, deoxycorticosterone, cortisol, and deoxycortisol: role of ACTH and angiotensin.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenocorticotropic Hormone; Aldosterone; Angiotensin II; | 1977 |
Metyrapone in long-term management of Cushing's disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Female; Hirsutism; Humans; Male; M | 1977 |
Metyrapone is useful only as adjunctive therapy in Cushing's disease.
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Glucocorticoids; Humans; Metyrapone | 1978 |
Surgical management of Cushing's syndrome.
Topics: Adenoma; Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocorticotropic Ho | 1978 |
Plasma ACTH radioimmunoassays in the diagnosis of pituitary-adrenal dysfunction.
Topics: Adrenal Insufficiency; Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethasone; Humans; Metyrap | 1977 |
Hypertension induced by adrenocortical dysfunction--hypertension in 17 alpha-hydroxylase deficiency and metopirone-induced hypertension.
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Animals; Cushing Syndrome; Deso | 1978 |
Treatment of Cushing's disease with adrenal blocking drugs and megavoltage therapy to the pituitary.
Topics: Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Aminoglutethimide; Cushing Syndrome; Female; | 1979 |
Cushing's syndrome due to adrenocortical carcinoma - a comphrensive clinical and biochemical study of patients treated by surgery and chemotherapy.
Topics: 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; Aldosterone; Carcinoma; Cort | 1979 |
Carcinoma of the lung presenting as Cushing's syndrome.
Topics: Aminoglutethimide; Carcinoma, Bronchogenic; Cortisone; Cushing Syndrome; Cyclophosphamide; Diagnosis | 1977 |
Cushing's syndrome.
Topics: Adenoma; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethasone; Humans; Metyrapone; Pitui | 1977 |
Evaluation of steroid laboratory tests and adrenal gland imaging with radiocholesterol in the aetiological diagnosis of Cushing's syndrome.
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Function Tests; Adrenal Glands; Adult; Aged; Cosyntropin | 1979 |
The continued importance of adrenalectomy in the treatment of Cushing's disease.
Topics: Adolescent; Adrenalectomy; Adult; Cushing Syndrome; Cyproheptadine; Female; Humans; Hypophysectomy; | 1979 |
Metastatic medullary carcinoma of the thyroid complicated by Cushing's syndrome.
Topics: Adult; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dexamethasone; Drug Therapy, Combination; Hum | 1979 |
Specific radioimmunoassay of human beta-endorphin in unextracted plasma.
Topics: Adenoma; Adrenal Gland Neoplasms; Carcinoma, Bronchogenic; Cushing Syndrome; Dexamethasone; Endorphi | 1979 |
Spontaneous remission of Cushing's disease. A case report and review of the literature.
Topics: Aged; Cushing Syndrome; Dexamethasone; Drug Therapy, Combination; Humans; Male; Metyrapone; Remissio | 1979 |
[Metopirone loading test].
Topics: 17-Hydroxycorticosteroids; Cushing Syndrome; Humans; Metyrapone | 1979 |
Evaluation of diagnostic and differential diagnostic tests in Cushing's syndrome.
Topics: Adult; Aged; Cushing Syndrome; Dexamethasone; Diagnosis, Differential; Evaluation Studies as Topic; | 1977 |
Feminizing adrenocortical carcinoma with Cushing's syndrome and pseudohyperparathyroidism.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult | 1978 |
Radioimmunoassay of human beta-lipotropin in unextracted plasma.
Topics: Acromegaly; beta-Lipotropin; Cushing Syndrome; Female; Humans; Hypopituitarism; Immune Sera; Male; M | 1977 |
Variation in response to dexamethasone of a patient with Cushing's syndrome.
Topics: Adenoma, Chromophobe; Adult; Cortodoxone; Cushing Syndrome; Dexamethasone; Female; Humans; Hydrocort | 1976 |
[Two cases of Cushing's disease with sudden remission after an episode of hysteria or administration of reserpine-metyrapone (author's transl)].
Topics: Adolescent; Cushing Syndrome; Female; Humans; Hysteria; Metyrapone; Reserpine | 1976 |
Single-dose metyrapone test: review of a four-year experience.
Topics: Adenoma, Chromophobe; Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Glands; | 1975 |
The immunological hazard of Cushing's syndrome.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Cryptococcosis; Cushing Syndrome; Female; Fluorouracil; Hum | 1975 |
Metyrapone test in Cushing's disease.
Topics: 17-Hydroxycorticosteroids; Administration, Oral; Adult; Cushing Syndrome; Evaluation Studies as Topi | 1975 |
Testing adrenal function--1975.
Topics: Adolescent; Adrenal Cortex Function Tests; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal | 1975 |
Cushing's syndrome with fluctuation due to adrenal adenoma.
Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Circadian Rh | 1975 |
[Effects of metyrapone administration on LH, FSH, TSH, and prolactin secretion].
Topics: Cushing Syndrome; Follicle Stimulating Hormone; Humans; Luteinizing Hormone; Male; Metyrapone; Prola | 1975 |
[Functional tests used in diagnosis of different forms of hypercorticism].
Topics: Adrenal Glands; Adrenocortical Hyperfunction; Cushing Syndrome; Dexamethasone; Dihydroxyphenylalanin | 1975 |
Paraneoplastic Cushing's syndrome as an adverse prognostic factor in patients who die early with small cell lung cancer.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Small Cell; Cushing Syndrome; Female; Humans; Lung Ne | 1992 |
[ACTH-independent Cushing's syndrome due to bilateral macronodular adrenal hyperplasia with empty sella turcica and anterior panhypopituitarism].
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Aged; Cushing Syndrome; Empty Sella Syndrome; Humans; H | 1992 |
Biochemical evaluation of adrenal dysfunction: the laboratory perspective.
Topics: Adolescent; Adrenal Insufficiency; Adrenocorticotropic Hormone; Adult; Aged; Child; Cushing Syndrome | 1992 |
Discordant changes in plasma ACTH and beta-lipotropin/beta-endorphin levels in Cushing's disease patients with depression.
Topics: Adrenocorticotropic Hormone; Adult; Aged; beta-Endorphin; beta-Lipotropin; Cushing Syndrome; Depress | 1992 |
Cushing's syndrome induced by hypersecretion of cortisol from only one of bilateral adrenocortical tumors.
Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adult; Cosyntropin; Cushing Syndrome; De | 1992 |
A case of asymptomatic cortisol producing adrenal adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Cushing Syndrome; Dexamethasone; Humans; Hydrocortisone; Hypothala | 1992 |
Variable hormonogenesis in Cushing's syndrome.
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexamethasone; Dose-Response Relationship, Dru | 1991 |
Short and long-term responses to metyrapone in the medical management of 91 patients with Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone; | 1991 |
[A case of familial medullary carcinoma of the thyroid complicated with Cushing's syndrome].
Topics: Adrenocorticotropic Hormone; Carcinoma; Circadian Rhythm; Cushing Syndrome; Dexamethasone; Humans; M | 1991 |
Effect of metyrapone pretreatment on adrenocorticotropin secretion induced by corticotropin-releasing hormone in normal subjects and patients with Cushing's disease.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushing Syndrome; D | 1990 |
Primary pigmented micronodular disease of the adrenals.
Topics: Adipose Tissue; Adolescent; Adrenal Cortex; Adrenal Medulla; Adrenocorticotropic Hormone; Cushing Sy | 1990 |
An evaluation of the distinction of ectopic and pituitary ACTH dependent Cushing's syndrome by clinical features, biochemical tests and radiological findings.
Topics: ACTH Syndrome, Ectopic; Adolescent; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexamethas | 1990 |
Adrenocorticotropin-independent bilateral macronodular adrenal hyperplasia: an unusual cause of Cushing's syndrome.
Topics: Adrenal Glands; Adrenal Hyperplasia, Congenital; Adrenalectomy; Adrenocorticotropic Hormone; Cushing | 1989 |
A new immunoradiometric assay for corticotropin evaluated in normal subjects and patients with Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cosyntr | 1989 |
[Investigation of Cushing's syndrome. The diagnostic value of the dexamethasone suppression test, the metopirone test and the CRF test].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Co | 1989 |
Megavoltage pituitary irradiation in the management of Cushing's disease and Nelson's syndrome: long-term follow-up.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Cushing Syndrome; Female; Follow-Up Studies; H | 1989 |
[Clinical significance of urinary 17-hydroxycorticoid and its component analysis in endocrine tests of the adrenal cortex].
Topics: 17-Hydroxycorticosteroids; Addison Disease; Adolescent; Adrenal Cortex Function Tests; Adrenal Hyper | 1989 |
Use of adrenal arterial embolization in severe ACTH-dependent Cushing's syndrome.
Topics: ACTH Syndrome, Ectopic; Adrenal Glands; Carcinoma; Combined Modality Therapy; Cushing Syndrome; Embo | 1989 |
Cushing's syndrome due to huge nodular adrenocortical hyperplasia with fluctuation of urinary 17-OHCS excretion.
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Cushing Syndrome; Dexamethasone; Humans; Hydrocortisone; | 1989 |
[Adrenostatic treatment of ACTH-dependent Cushing syndrome using metyrapone and aminoglutethimide].
Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Aminoglutethimide; Cushing Syn | 1987 |
Ectopic ACTH syndrome caused by a bronchial carcinoid tumor responsive to dexamethasone, metyrapone, and corticotropin-releasing factor.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Bronchial Neoplasms; Carcinoid Tumor; Co | 1988 |
Effect of ovine corticotrophin releasing factor, bromocriptine, and dopamine on release of ACTH and beta-endorphin in a patient with Cushing's disease.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Animals; beta-Endorphin; Bromocriptine; Corticotropin-R | 1985 |
Nocturnal high-dose dexamethasone suppression test in the aetiological diagnosis of Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Cortodoxone; Cushin | 1985 |
Immunoreactive corticotropin-releasing factor in human plasma.
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Chromatography, High Pressure Liquid; Co | 1985 |
Cushing's syndrome presenting the coexistence of a pituitary corticotrophic cell hyperplasia and a unilateral functional adrenal adenoma.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Circadian Rhythm; Cush | 1985 |
Hypothalamo-pituitary-adrenal axis in iatrogenic Cushing's syndrome.
Topics: Adolescent; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aged; Cushing Syndrome; Fem | 1985 |
Primary therapy for Cushing's disease with metyrapone.
Topics: Adolescent; Adrenocorticotropic Hormone; Circadian Rhythm; Cortodoxone; Cushing Syndrome; Drug Admin | 1986 |
Alopecia associated with long-term metyrapone use.
Topics: Adrenocorticotropic Hormone; Aged; Alopecia; Cushing Syndrome; Female; Humans; Metyrapone | 1986 |
Successful control of Cushing's disease in the elderly with long term metyrapone.
Topics: Adrenocorticotropic Hormone; Age Factors; Aged; Cortodoxone; Cushing Syndrome; Female; Humans; Hydro | 1986 |
Plasma ACTH in diagnosis and control of adrenal disorders.
Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adre | 1986 |
Cortisol responsiveness to insulin-induced hypoglycemia in Cushing's syndrome with huge nodular adrenocortical hyperplasia.
Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Angiotensin II; Arginine Vasopressin; Circadian Rhythm; | 1986 |
Differential effects of the imidazole derivatives etomidate, ketoconazole and miconazole and of metyrapone on the secretion of cortisol and its precursors by human adrenocortical cells.
Topics: 17-alpha-Hydroxyprogesterone; Adrenal Cortex; Adrenocorticotropic Hormone; Cortodoxone; Cushing Synd | 1987 |
Plasma immunoreactive proopiomelanocortin peptides and cortisol in normal dogs and dogs with Cushing's syndrome: diurnal rhythm and responses to various stimuli.
Topics: Animals; Blood Glucose; Circadian Rhythm; Cushing Syndrome; Dexamethasone; Dogs; Dopamine; Female; H | 1988 |
Totally automated liquid-chromatographic assay for cortisol and associated glucocorticoids in serum, with use of ASTED sample preparation.
Topics: Adrenal Hyperplasia, Congenital; Autoanalysis; Chromatography, High Pressure Liquid; Cushing Syndrom | 1988 |
The corticotropin-releasing factor test in the diagnosis of ectopic ACTH secretion.
Topics: ACTH Syndrome, Ectopic; Adenocarcinoma; Aged; Corticotropin-Releasing Hormone; Cushing Syndrome; Dex | 1987 |
Cushing's syndrome secondary to ectopic corticotropin-releasing hormone-adrenocorticotropin secretion.
Topics: ACTH Syndrome, Ectopic; Bronchial Neoplasms; Carcinoid Tumor; Corticotropin-Releasing Hormone; Cushi | 1986 |
A competitive enzyme-linked immunosorbent assay for plasma 11-deoxycortisol (17,21-dihydroxy-4-pregnene-3,20-dione).
Topics: 17-Hydroxycorticosteroids; Animals; Cortodoxone; Cushing Syndrome; Enzyme-Linked Immunosorbent Assay | 1986 |
Primary pigmented nodular adrenocortical disease: diagnosis and management.
Topics: Adolescent; Adrenal Cortex Diseases; Adrenalectomy; Adult; Child; Cushing Syndrome; Dexamethasone; D | 1986 |
Metyrapone for depression and delirium secondary to Cushing's syndrome.
Topics: Cushing Syndrome; Delirium; Depressive Disorder; Humans; Male; Metyrapone; Middle Aged | 1985 |
Pregnancy complicated by Cushing's syndrome: potential hazard of metyrapone therapy. Case report.
Topics: Adult; Cushing Syndrome; Female; Humans; Hypertension; Metyrapone; Pregnancy; Pregnancy Complication | 1985 |
Malignant melanoma with ectopic production of adrenocorticotropic hormone. Palliative treatment with inhibitors of adrenal steroid biosynthesis.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon | 1973 |
Remission of Cushing's disease after administration of adrenocorticotropin.
Topics: 17-Hydroxycorticosteroids; Administration, Oral; Adrenal Glands; Adrenal Insufficiency; Adrenocortic | 1974 |
Deep sleep phase alterations in patients with loss of the adrenal secretory rhythm and in hypophysectomized patients. (The effects of hypothalamo-hypophyseal stressing by metopyron).
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethasone; Electroencephalography; Eye Movements; | 1967 |
Patterns of urinary excretion of steroids in Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; A | 1966 |
Studies in a patient with an ectopic adrenocortical tumor.
Topics: 17-Hydroxycorticosteroids; Adenocarcinoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotrop | 1966 |
Intermittent Cushing's syndrome with anomalous response to dexamethasone.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethas | 1966 |
Evaluation of the efficiency of 11-beta-hydroxylation of 11-deoxycortisol in human subjects.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Cushing Syndrome; Desoxycorticosterone; Estrogens; Huma | 1967 |
Suppression of tumorous adrenal hyperfunction by aminoglutethimide.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfu | 1967 |
Pituitary-adrenocortical studies in a patient with Cushing's syndrome induced by thymoma.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dex | 1967 |
Epiandrosterone excretion in man.
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Cushing Syndrome; Fem | 1967 |
Cushing's syndrome in association with a carcinoid tumor of the lung.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Carcinoid Tumor; Cushing Sy | 1967 |
Failure of metyrapone to inhibit 11-hydroxylation of 11-deoxycortisol during drug therapy.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Chromatography, Paper; Chrom | 1967 |
The assessment of hypothalamic-pituitary-adrenocortical function in man.
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Female; Humans; Hydrocortisone; Insulin; Liver Diseas | 1967 |
Cushing's syndrome associated with a "corticotrophin"-producing bronchial neoplasm neoplasm (results of corticotrophin assays and of pituitary-adrenal function tests).
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenocortical Hyperfunction; Adrenocorticotropi | 1967 |
Nycthemeral rhythm of plasma cortisol levels in the Cushing's syndrome associated with hyperplasia of adrenal cortex, before and after treatment of hypophyseal suppression with ultrasonic technique.
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Circadian Rhy | 1967 |
Sequential solvent extraction of urinary corticosteroids and its clinical application.
Topics: 17-Hydroxycorticosteroids; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenocorticotrop | 1967 |
A fundamental defect of adrenocortical control in Cushing's disease.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenalectomy; Adren | 1968 |
[Intercurrent relationships between nyctohemeral rhythm of elimination of gonadotropins and adrenal cortex steroids].
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Circadian Rhythm; Cushing Syndrome; Dexameth | 1967 |
[Functional evaluation of the pituitary gland with the metyrapone test and determination of ACTH in the blood].
Topics: Acromegaly; Adrenal Insufficiency; Adrenocorticotropic Hormone; Cushing Syndrome; Humans; Hypopituit | 1967 |
Cushing's syndrome caused by bronchial adenomas.
Topics: Adenoma; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Biological Assay; Bronchial Neoplasms; C | 1968 |
[Patterns of adrenal steroids present in the blood].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aldosterone; Blood Proteins; Corticosterone; C | 1967 |
Successful metyrapone therapy of the ectopic ACTH syndrome.
Topics: Adolescent; Adrenocorticotropic Hormone; Biopsy; Carcinoma; Cushing Syndrome; Cyclophosphamide; Horm | 1968 |
Hypothalamo-pituitary-adrenal function in hypercorticosteroid states.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexamethasone; Feed | 1968 |
[Pituitary syndromes of diencephalic origin. Clinical application of pituitary stimulation tests].
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenal Insufficiency; Adrenocorticotropic Hormon | 1968 |
[Progress in the clinical pathology of the adrenal cortex].
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Child; Cushing Synd | 1967 |
Vasopressin in the evaluation of pituitary-adrenal function.
Topics: Acromegaly; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Anorex | 1968 |
Medullary carcinoma of the thyroid--a cause of Cushing's syndrome: report of two cases.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Carci | 1968 |
Radioimmunoassay of ACTH in plasma.
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Con | 1968 |
[Endoccinological changes as a result of obesity in juveniles].
Topics: Adolescent; Adrenocorticotropic Hormone; Age Factors; Blood Glucose; Body Height; Body Weight; Cushi | 1968 |
Cushing's syndrome induced by the ectopic production of ACTH by a bronchial carcinoid.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Aged; Bronchial Neoplasms; | 1969 |
A simple method for the separate estimation of 11-deoxy and 11-oxygenated 17-hydroxycortico-steroids in human urine.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adr | 1968 |
[Functional exploration of the adrenal cortex in basal and dynamic conditions in hypercorticism of the Cushing type].
Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocortical Hyperfu | 1968 |
[Clinical studies on the stimulation and suppression of the pituitary-adrenocortical system. II. Studies on the pituitary-adrenocortical suppression test].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; C | 1968 |
[Present state of the dynamic studies of the adrenal cortex (excepting and aldosterone function)].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adrenal Gland Neoplasms; Adrenal Insuff | 1968 |
[Fractional determination of 4 types of neutral steroid glucuronides (11-deoxy-C-19 steroid, 11-deoxy-C-21 steroid, 11-oxy-C-19 steroid, 11-oxy-C-21 steroid) and 3 types of steroid glucuronides (11-deoxy-neutral steroid, pregnanediol, 11-oxy-neutral stero
Topics: Adrenal Insufficiency; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Castration; | 1969 |
Metyrapone and pyrogen tests in hyperadrenocorticism: evaluation of blood corticotropin levels.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Animals; Biological Assay; Corticosterone; Cushing S | 1968 |
Normal and abnormal regulation of beta-msh in man.
Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, C | 1969 |
Diagnosis of Cushing's syndrome. The differentiation between adrenocortical hyperplasia and adrenocrotical adenoma by means of lysine-vasopressin.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone | 1969 |
Radioimmunoassayable ACTH in dexamethasone nonsuppressible Cushing's syndrome.
Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Chemistry, Clinical; Cushing Syndr | 1969 |
[Evaluation of the pituitary ACTH reserve in patients irradiated for cerebral neoplasms].
Topics: Acromegaly; Adrenocorticotropic Hormone; Adult; Astrocytoma; Brain Neoplasms; Cushing Syndrome; Fema | 1968 |
Cushing's syndrome with a paradoxical response to dexamethasone.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Basophil; Adrenalectomy; Adrenocortical Hyperfu | 1969 |
[Diurnal variation of plasma cortisol concentration in patients with various diseases and negative feedback mechanism of the pituitary-adrenal axis].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Central Nervous Sys | 1969 |
Anomalous response to metyrapone in Cushing's syndrome due to adrenocortical adenoma.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Cus | 1970 |
Evaluation of stimulation and suppression tests in the etiological diagnosis of Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Ang | 1969 |
[Broncho-pulmonary cancer with true or degraded hypercorticism].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon | 1969 |
"Cure" of ectopic ACTH syndrome secondary to adrenocarcinoma of the lung.
Topics: 17-Ketosteroids; Acid Phosphatase; Adenocarcinoma; Adrenocorticotropic Hormone; Cushing Syndrome; Cy | 1970 |
[Gas liquid chromatography analysis of urinary neutral steroid fractions in normal persons and patients with various diseases].
Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormon | 1970 |
[Diagnosis and management of Cushing' syndrome based on our 28 cases, with special reference to combined therapy of 60Co irradiation of the hypothalamus and reserpine].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Child; Cobalt Isotopes; C | 1970 |
Cushing's syndrome caused by a metyrapone responsive adrenocortical adenoma.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Horm | 1970 |
Tests in cushing's syndrome.
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethasone; Humans; Metyrapone | 1970 |
Cushing's syndrome, a personal view.
Topics: Adrenocorticotropic Hormone; Cushing Syndrome; Feedback; Humans; Hydrocortisone; Metyrapone; Stress, | 1970 |
[Poly-micro-adenomatosis in Cushing's syndrome].
Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Cushing Syndr | 1970 |
[Biochemical diagnosis of adrenal cortex function].
Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormon | 1970 |
[Diagnosis of Cushing's syndrome].
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexamethasone; Diag | 1970 |
[Correlation of ACTH and MSH in man].
Topics: Addison Disease; Adrenocorticotropic Hormone; Cross Reactions; Cushing Syndrome; Hormones, Ectopic; | 1970 |
Cushing's syndrome caused by malignant tumor in the scrotum: clinical, pathologic and biochemical studies.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Rest Tumor; Adrenocorticotropic Hormone; Androst | 1971 |
[Pituitary corticotropin function in hypertonic obesity "with rose striae"].
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Diagnosis, Differential; Female; Humans; Hyper | 1970 |
A new phenomenon of usefulness in the radioimmunoassay of plasma adrenocorticotropic hormone.
Topics: Addison Disease; Administration, Oral; Adrenalectomy; Adrenocorticotropic Hormone; Circadian Rhythm; | 1971 |
[Radioimmunoassay of ACTH].
Topics: 17-Hydroxycorticosteroids; Addison Disease; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Ho | 1971 |
Results of treatment in 108 patients with Cushing's syndrome.
Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Age | 1971 |
Therapeutic possibilities in Cushing's syndrome.
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Hormones, Ectopic; | 1971 |
[Cushing's syndrome].
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexametha | 1971 |
Detection of an ACTH-secreting bronchial carcinoid tumour eighteen months after adrenalectomy for Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Bronc | 1971 |
[Pituitary function test using synthetic lysine-8-vasopressin--comparison with metopirone test and insulin stress test].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anorexia Nervosa; Craniopharyngioma; Cushing S | 1971 |
[Study of plasma ACTH in 100 human lysine-vasopressin tests].
Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Glands; Adrenalectomy; Adrenocorticotro | 1971 |
Tests of adrenocortical function.
Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocorticotropic Hormone; Cushing Syndrome; Dexam | 1971 |
Size heterogeneity of immunoreactive human ACTH in plasma and in extracts of pituitary glands and ACTH-producing thymoma.
Topics: Addison Disease; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Antigens; Chromatography, Gel; | 1971 |
A comparison of bioassay and radioimmunoassay for plasma corticotropin in man.
Topics: Addison Disease; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Antigens; Biol | 1972 |
[Behavior of adrenocorticotropic internal secretions in Cushing's syndrome].
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Circadian Rhythm; Cu | 1970 |
Recurrent Cushing's disease following "total" adrenalectomy.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormo | 1972 |
[Function studies of the hypothalamus-anterior-pituitary-adrenal cortex system following surgery of cortisol-producing adrenal gland adenoma].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Insufficienc | 1972 |
Extra-adrenal action of metyrapone upon human growth hormone secretion in man.
Topics: Addison Disease; Adrenalectomy; Adrenocorticotropic Hormone; Blood Glucose; Cushing Syndrome; Growth | 1972 |
Measurement of pituitary hormones: clinical applications. 2. Corticotrophin.
Topics: Addison Disease; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Circadian Rhythm; Cushing Synd | 1972 |
Cushing's disease with periodic hormonogenesis: one explanation for paradoxical response to dexamethasone.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethasone; Dihydroxyph | 1973 |
[Diagnosis and therapy of endogenic hypercortisolism (Cushing's syndrome)].
Topics: Adrenalectomy; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexamethasone; Diagnosis, Diffe | 1972 |
[Medical therapy of hyperadrenalism].
Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Aminoglutethimide; Cushing Syndrome; Huma | 1973 |
[Urinary 6beta-hydroxycortisol. II. Urinary 6beta-hydroxycortisol in different diseases and after administration of drugs].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Carcinoma; Cushing Syndrome; F | 1973 |
Iatrogenic Cushing's disease in a boy after misdiagnosis of salt-losing virilizing adrenal hyperplasia: impaired metyrapone response with failure of catch-up growth.
Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenocorticotropic Hormone | 1973 |
[Importance of the study of corticotropin circadian rhythm in the functional symptomatology of the ACTH-adrenal axis].
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Anorexia Nervosa; Cir | 1974 |
Spontaneous and stimulated secretion of QUSO-extractable immunoassayable ACTH in man.
Topics: Addison Disease; Adrenalectomy; Adrenocorticotropic Hormone; Cushing Syndrome; Humans; Lysine; Metho | 1974 |
Cushing's disease with cure by resection of a pituitary adenoma. Evidence against a primary hypothalamic defect.
Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Cushing Syndrome; Depression, Chemica | 1974 |
Treatment of Cushing's disease with adrenal blocking drugs and megavoltage therapy to the pituitary.
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushing Syndrome; Fem | 1974 |
The adrenal cortex (excluding aldosteronism).
Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex; Adrenal Gland Diseases; Adrenal Glands; Adrenocort | 1974 |
Cushing's syndrome with dual pituitary-adrenal control.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Cushin | 1970 |
Cytochrome P450 and steroid 11beta-hydroxylation in mitochondria from human adrenal cortex.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Antimycin A; Breast Neoplasms; Carbon Monoxide; Cushing S | 1968 |
[Urinary steroids under the effect of standardized dynamic tests].
Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotropin; Cryptorchidism; | 1972 |
[Proceedings: Cushing's syndrome in hypernephroid carcinoma; normalization of the cortisol value, hypokalemia and hypertension under metopirone].
Topics: Adenocarcinoma; Cushing Syndrome; Humans; Hydrocortisone; Hypertension; Hypokalemia; Kidney Neoplasm | 1974 |
Use of corticosteroids.
Topics: Addison Disease; Administration, Oral; Adolescent; Adrenocortical Hyperfunction; Age Factors; Asthma | 1974 |
[Endocrine regulation of adrenal function (author's transl)].
Topics: Addison Disease; Circadian Rhythm; Cushing Syndrome; Dexamethasone; Humans; Hypothalamo-Hypophyseal | 1974 |
Diagnostic and therapeutic problems in spontaneous Cushing's syndrome. A review with five case reports.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adrenalectomy; Adult; Circadian Rhythm; | 1972 |
Temporal rhythm in the response of urinary 17-OHCS to metopirone in Cushing's syndrome due to bilateral adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Circadian Rhythm; Cushing Syndrome; Feedback; Female; Hum | 1973 |
Cushing's syndrome. An evaluation of the clinical usefulness of urinary free cortisol and other urinary steroid measurements in diagnosis.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Glands; Adult; Blood Proteins; Child; Creatinine | 1973 |
An assessment of the metyrapone test.
Topics: Adrenal Gland Neoplasms; Adult; Aged; Chromatography, Gas; Cushing Syndrome; Diagnosis, Differential | 1973 |
Cushing's syndrome due to bilateral adrenal cortical hyperplasia in a 13-year old girl: successful treatment with op'DDD'.
Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Body Height; Body Weig | 1974 |
Cushing's disease in a boy: serial steroid and growth hormone studies.
Topics: 17-Hydroxycorticosteroids; Adrenalectomy; Arginine; Child; Cushing Syndrome; Dexamethasone; Diagnosi | 1969 |
Persistent or recurrent Cushing's syndrome after "total" adrenalectomy: adrenal photoscanning for residual tissue.
Topics: 17-Hydroxycorticosteroids; Adrenalectomy; Adult; Cholesterol; Cushing Syndrome; Dexamethasone; Femal | 1972 |
Immediate effect of unilateral adrenalectomy followed by external pituitary irradiation on cortisol secretion rate in subjects suffering from pituitary dependent Cushing's syndrome.
Topics: Adrenalectomy; Adult; Cushing Syndrome; Dexamethasone; Female; Follow-Up Studies; Humans; Hydrocorti | 1971 |
Excretion of urinary free amino acids in Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Amino | 1969 |
Tests of hypothalamic-pituitary-adrenal function in man.
Topics: Acromegaly; Adrenal Glands; Adult; Aged; Cushing Syndrome; Female; Fever; Glucocorticoids; Growth Ho | 1969 |
[Diagnosis of disturbances of adrenal cortex function].
Topics: 17-Hydroxycorticosteroids; Addison Disease; Adolescent; Adrenal Cortex Hormones; Adult; Cushing Synd | 1969 |
Use of lysin-vasopressin in the differential diagnosis of cushing's syndrome.
Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cushing Syndrome; Diagnosis, Differential; Female; Hu | 1970 |
[2 cases of Cushing's disease with a hypokalemic alkalosis syndrome].
Topics: Adrenalectomy; Adult; Alkalosis; Calcium; Cushing Syndrome; Female; Humans; Hypokalemia; Metyrapone; | 1967 |
[Hypothalamo-hypophyseo-adrenocortical response to insulin-induced hypoglycemia].
Topics: Acromegaly; Adenoma, Chromophobe; Adrenal Cortex Hormones; Adult; Blood Glucose; Craniopharyngioma; | 1967 |
[Clinical studies on urinary 17-ketogenic steroid fractions. 3. SU-4885 test in normal subjects and the patients with various endocrine disorders].
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland N | 1968 |
[Differentiated evaluation of metopirone test by thin layer chromatography].
Topics: Addison Disease; Adrenal Cortex Hormones; Adult; Child; Child, Preschool; Chromatography, Thin Layer | 1968 |
A simplified metyrapone test with determination of plasma ll-deoxycortisol (Metyrapone test with plasma S).
Topics: 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocortical Hyperfunct | 1969 |
Cushing's syndrome in infancy.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Abnormalities, Multiple; Adenoma; Adrenal Gland Neoplasm | 1969 |
[Anterior pituitary lobe activity and demonstration of an exophthalmos producing factor (EPF) in serum].
Topics: Cushing Syndrome; Endocrine System Diseases; Exophthalmos; Humans; Metyrapone; Pituitary Gland; Thyr | 1965 |
[Treatment of Cushing's syndrome].
Topics: Cushing Syndrome; Dexamethasone; Humans; Hypophysectomy; Metyrapone; Pituitary Irradiation | 1966 |
Some factors determining the adrenal response to metyrapone (SU 4885).
Topics: Cushing Syndrome; Desoxycorticosterone; Humans; Hydrocortisone; Metyrapone; Pituitary-Adrenal Functi | 1966 |
Failure of dexamethasone suppression in adrenal hyperplasia.
Topics: Adrenal Gland Neoplasms; Adult; Cushing Syndrome; Dexamethasone; Diagnosis, Differential; Humans; Hy | 1966 |