metyrapone has been researched along with Craniopharyngioma in 19 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Craniopharyngioma: A benign pituitary-region neoplasm that originates from Rathke's pouch. The two major histologic and clinical subtypes are adamantinous (or classical) craniopharyngioma and papillary craniopharyngioma. The adamantinous form presents in children and adolescents as an expanding cystic lesion in the pituitary region. The cystic cavity is filled with a black viscous substance and histologically the tumor is composed of adamantinomatous epithelium and areas of calcification and necrosis. Papillary craniopharyngiomas occur in adults, and histologically feature a squamous epithelium with papillations. (From Joynt, Clinical Neurology, 1998, Ch14, p50)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Evaluation of single-dose metyrapone tests in children with hypopituitarism; comparison with the prolonged metyrapone and insulin induced hypoglycaemia tests and their relationship with the etiology of hypopituitarism." | 7.65 | Evaluation of single oral dose metyrapone tests in children with hypopituitarism. ( Basmaciogullari, A; Limal, JM; Rappaport, R, 1976) |
| "Evaluation of single-dose metyrapone tests in children with hypopituitarism; comparison with the prolonged metyrapone and insulin induced hypoglycaemia tests and their relationship with the etiology of hypopituitarism." | 3.65 | Evaluation of single oral dose metyrapone tests in children with hypopituitarism. ( Basmaciogullari, A; Limal, JM; Rappaport, R, 1976) |
| "A 52-year-old woman experienced hypoadrenalism (mean 8 AM plasma cortisol level, 3." | 1.26 | Stress-induced cortisol release in hypothalamic hypoadrenalism. ( Glass, AR; Smith, CE, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (94.74) | 18.7374 |
| 1990's | 1 (5.26) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| RODRIGUEZDORESTE, OL | 1 |
| MAS, S | 1 |
| RICHMOND, L | 1 |
| CHAPPELL, J | 1 |
| CLEVELAND, WW | 1 |
| KEPES, JJ | 1 |
| REECE, CA | 1 |
| OXLEY, DK | 1 |
| Nishida, S | 3 |
| Ando, M | 1 |
| Katsuki, S | 2 |
| Fujiwara, I | 1 |
| Igarashi, Y | 1 |
| Ogawa, E | 1 |
| Glass, AR | 1 |
| Smith, CE | 1 |
| Limal, JM | 1 |
| Basmaciogullari, A | 1 |
| Rappaport, R | 1 |
| Laurberg, P | 1 |
| Møller, J | 1 |
| Husager, L | 1 |
| Weeke, J | 1 |
| Martin, MM | 1 |
| Laron, Z | 1 |
| Karp, M | 1 |
| Pertzela, A | 1 |
| Frankel, J | 1 |
| Nakajima, T | 1 |
| Faglia, G | 2 |
| Ambrosi, B | 2 |
| Beck-Peccoz, P | 2 |
| Giovanelli, M | 1 |
| Lundberg, PO | 1 |
| Wide, L | 1 |
| Travaglini, P | 1 |
| Nakazawa, S | 1 |
| Ueki, K | 1 |
| Uozumi, T | 1 |
| Mori, S | 1 |
| Watanabe, M | 1 |
| Takimoto, N | 1 |
| Mogami, H | 1 |
| Feurle, G | 1 |
| Reisert, PM | 1 |
| Emrich, D | 1 |
| König, A | 1 |
| Bushe, KA | 1 |
| Kenny, FM | 1 |
| Iturzaeta, NF | 1 |
| Mintz, D | 1 |
| Drash, A | 1 |
| Garces, LY | 1 |
| Susen, A | 1 |
| Askari, HA | 1 |
2 trials available for metyrapone and Craniopharyngioma
| Article | Year |
|---|---|
A comparison of pituitary-adrenal responses to corticotropin-releasing hormone, hypoglycaemia and metyrapone in children with brain tumours and growth hormone deficiency.
Topics: Adolescent; Adrenocorticotropic Hormone; Brain Neoplasms; Child; Child, Preschool; Corticotropin-Rel | 1995 |
ACTH deficiency in children and adolescents (clinical and psychological aspects).
Topics: Adolescent; Adrenocorticotropic Hormone; Child; Clinical Trials as Topic; Craniopharyngioma; Female; | 1970 |
17 other studies available for metyrapone and Craniopharyngioma
| Article | Year |
|---|---|
[STUDY OF PITUITARY FUNCTION WITH THE NEW METHOPYRAPONE TEST].
Topics: Achondroplasia; Adolescent; Adrenal Cortex Hormones; Craniopharyngioma; Diagnosis, Differential; Dwa | 1963 |
RESPONSE OF CHILDREN TO METHOPYRAPONE (METOPIRONE).
Topics: Adolescent; Adrenal Cortex Hormones; Brain Diseases; Child; Craniopharyngioma; Craniosynostoses; Dia | 1964 |
CENTRAL PONTINE MYELINOLYSIS IN A 7-YEAR-OLD BOY.
Topics: Child; Craniopharyngioma; Dehydration; Demyelinating Diseases; Humans; Ketones; Male; Metyrapone; Mi | 1965 |
[Metopirone test and lateral dimensions of the sella turcica in pituitary tumor].
Topics: Acromegaly; Adenoma, Chromophobe; Adolescent; Adult; Craniopharyngioma; Diagnosis, Differential; Fem | 1966 |
Stress-induced cortisol release in hypothalamic hypoadrenalism.
Topics: 17-Hydroxycorticosteroids; Adrenal Insufficiency; Adrenocorticotropic Hormone; Circadian Rhythm; Cra | 1979 |
Evaluation of single oral dose metyrapone tests in children with hypopituitarism.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Arginine; Blood Glucose; Child; Cortodoxone; Craniopha | 1976 |
Evaluation of pituitary-adrenal function after pituitary surgery.
Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Cortodoxone; Cranio | 1985 |
Coexisting anterior pituitary and neurohypophyseal insufficiency. A syndrome with diagnostic implication.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Biopsy; | 1969 |
[Pituitary function test using synthetic lysine-8-vasopressin--comparison with metopirone test and insulin stress test].
Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Anorexia Nervosa; Craniopharyngioma; Cushing S | 1971 |
Disorders of growth hormone and corticotropin regulation in patients with empty sella.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma, Chromophobe; Adrenocorticotropic Hormone; Adult | 1973 |
The response to TRH, LH-RH, metyrapone and vasopressin in patients with hypothalamo-pituitary disorders.
Topics: Acromegaly; Adenoma, Acidophil; Adenoma, Chromophobe; Adult; Brain Neoplasms; Craniopharyngioma; Dia | 1973 |
Hypothalamic-pituitary-adrenal function in patients with pituitary tumours.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma, Chromophobe; Adolescent; Adrenal Glands; Adrenocorti | 1973 |
[Endocrine, water and electrolyte abnormalities of craniopharyngioma (author's transl)].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex; Adrenocorticotropic Hormone; | 1974 |
[Endocrinological evaluation of sellar and suprasellar tumor cases --the first report-- on preoperative pituitary function (author's transl)].
Topics: Adenoma; Adolescent; Adrenocorticotropic Hormone; Adult; Brain Neoplasms; Child; Chordoma; Craniopha | 1974 |
[Clinical and endocrinologic diagnosis of pituitary and suprasellar tumors].
Topics: Acromegaly; Adenoma, Chromophobe; Craniopharyngioma; Female; Headache; Humans; Hypogonadism; Insulin | 1970 |
[Hypothalamo-hypophyseo-adrenocortical response to insulin-induced hypoglycemia].
Topics: Acromegaly; Adenoma, Chromophobe; Adrenal Cortex Hormones; Adult; Blood Glucose; Craniopharyngioma; | 1967 |
Iatrogenic hypopituitarism in craniopharyngioma: unexplained catch-up growth in three children.
Topics: 17-Hydroxycorticosteroids; Body Height; Body Weight; Bone Development; Child; Child, Preschool; Cran | 1968 |