metyrapone has been researched along with Coronary Disease in 5 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (60.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Broadley, AJ | 2 |
| Korszun, A | 2 |
| Abdelaal, E | 2 |
| Moskvina, V | 2 |
| Jones, CJ | 2 |
| Nash, GB | 1 |
| Ray, C | 1 |
| Deanfield, J | 2 |
| Frenneaux, MP | 2 |
| Gorbachev, VV | 1 |
| Livshits, IB | 1 |
| Friedman, M | 1 |
| Rosenman, RH | 1 |
| St George, S | 1 |
| Ferrari, E | 1 |
| Tronconi, L | 1 |
| Bossolo, PA | 1 |
| Pallavicini, S | 1 |
| Baldrighi, V | 1 |
2 trials available for metyrapone and Coronary Disease
| Article | Year |
|---|---|
Inhibition of cortisol production with metyrapone prevents mental stress-induced endothelial dysfunction and baroreflex impairment.
Topics: Adult; Baroreflex; Blood Pressure; Brachial Artery; Coronary Disease; Double-Blind Method; Electroca | 2005 |
Metyrapone improves endothelial dysfunction in patients with treated depression.
Topics: Adult; Antidepressive Agents; Brachial Artery; Coronary Disease; Depressive Disorder; Double-Blind M | 2006 |
3 other studies available for metyrapone and Coronary Disease
| Article | Year |
|---|---|
[Somatotropic function of the hypophysis in arteriosclerosis].
Topics: Adult; Aged; Animals; Coronary Disease; Female; Glucose Tolerance Test; Growth Hormone; Humans; Hype | 1976 |
Adrenal response to excess corticotropin in coronary-prone men.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Coronary Disease; Dis | 1969 |
[The functional state of the pituitary-adrenal system in chronic coronary insufficiency].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adult; Aged; Angiography; Chronic Disease; Coronary Dise | 1968 |