metyrapone has been researched along with Complications, Pregnancy in 21 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To control hypercortisolism, the patient was treated with metyrapone." | 6.41 | Recurrent ACTH-independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone. ( Dokoupilová, M; Hána, V; Marek, J; Plavka, R, 2001) |
| "The ketoconazole was shift to metyrapone but afterwards ketoconazole was added again." | 5.46 | A successful case of pregnancy in a woman with ACTH-independent Cushing's syndrome treated with ketoconazole and metyrapone. ( Michalak, R; Zieleniewski, W, 2017) |
| "Hypercortisolism was successfully controlled with metyrapone, which was started at 8 weeks of gestation." | 5.33 | Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy. ( Blanco, C; Maqueda, E; Rodriguez, A; Rubio, JA, 2006) |
| "The hypercortisolism was controlled with metyrapone until elective delivery of the fetus by Caesarean section at 34 weeks gestation because of a decline in growth." | 5.29 | ACTH-independent Cushing's syndrome in pregnancy with spontaneous resolution after delivery: control of the hypercortisolism with metyrapone. ( Close, CF; Mann, MC; Taylor, KG; Watts, JF, 1993) |
| " Maternal treatment with dexamethasone on day 15 of pregnancy mimicked the stress effect and reproduced the AI and AHR outcomes, whereas blockade of the stress-induced corticosterone surge with metyrapone pretreatment of pregnant mice abrogated the effect." | 3.80 | Maternal stress during pregnancy increases neonatal allergy susceptibility: role of glucocorticoids. ( Fedulov, AV; Kobzik, L; Lim, R, 2014) |
| "Pregnancy-induced Cushing's syndrome is exceptionally rare with fewer than ten cases reported in the world literature and none in Australia or New Zealand." | 2.48 | Pregnancy-induced Cushing's syndrome in recurrent pregnancies: case report and literature review. ( Achong, N; D'Emden, M; Fagermo, N; Mortimer, R, 2012) |
| "The most common cause of endogenous Cushing's disease in children older than 7 years is ACTH-dependent Cushing's disease (85%)." | 2.45 | [Cushing's syndrome: special issues]. ( Goñi Iriarte, MJ, 2009) |
| "To control hypercortisolism, the patient was treated with metyrapone." | 2.41 | Recurrent ACTH-independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone. ( Dokoupilová, M; Hána, V; Marek, J; Plavka, R, 2001) |
| "The ketoconazole was shift to metyrapone but afterwards ketoconazole was added again." | 1.46 | A successful case of pregnancy in a woman with ACTH-independent Cushing's syndrome treated with ketoconazole and metyrapone. ( Michalak, R; Zieleniewski, W, 2017) |
| "Hypercortisolism was successfully controlled with metyrapone, which was started at 8 weeks of gestation." | 1.33 | Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy. ( Blanco, C; Maqueda, E; Rodriguez, A; Rubio, JA, 2006) |
| "The hypercortisolism was controlled with metyrapone until elective delivery of the fetus by Caesarean section at 34 weeks gestation because of a decline in growth." | 1.29 | ACTH-independent Cushing's syndrome in pregnancy with spontaneous resolution after delivery: control of the hypercortisolism with metyrapone. ( Close, CF; Mann, MC; Taylor, KG; Watts, JF, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (52.38) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 5 (23.81) | 29.6817 |
| 2010's | 4 (19.05) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lim, R | 1 |
| Fedulov, AV | 1 |
| Kobzik, L | 1 |
| Zieleniewski, W | 1 |
| Michalak, R | 1 |
| Goñi Iriarte, MJ | 1 |
| Achong, N | 1 |
| D'Emden, M | 1 |
| Fagermo, N | 1 |
| Mortimer, R | 1 |
| Lim, WH | 1 |
| Torpy, DJ | 1 |
| Jeffries, WS | 1 |
| Lubin, V | 1 |
| Gautier, JF | 1 |
| Antoine, JM | 1 |
| Beressi, JP | 1 |
| Vexiau, P | 1 |
| HEINEN, G | 1 |
| BUCHHEIT, H | 1 |
| OERTEL, GW | 1 |
| KERNOHAN, RJ | 1 |
| Blanco, C | 1 |
| Maqueda, E | 1 |
| Rubio, JA | 1 |
| Rodriguez, A | 1 |
| Gormley, MJ | 1 |
| Hadden, DR | 1 |
| Kennedy, TL | 1 |
| Montgomery, DA | 1 |
| Murnaghan, GA | 1 |
| Sheridan, B | 1 |
| Close, CF | 1 |
| Mann, MC | 1 |
| Watts, JF | 1 |
| Taylor, KG | 1 |
| Kasperlik-Zaluska, AA | 1 |
| Szczupacka, I | 1 |
| Leszczynska-Bystrzanowska, J | 1 |
| Drus-Przybyszewska, G | 1 |
| Hána, V | 1 |
| Dokoupilová, M | 1 |
| Marek, J | 1 |
| Plavka, R | 1 |
| Groos, G | 1 |
| Tharandt, L | 1 |
| Benker, G | 1 |
| Zäh, W | 1 |
| Hackenberg, K | 1 |
| Reinwein, D | 1 |
| Connell, JM | 1 |
| Cordiner, J | 1 |
| Davies, DL | 1 |
| Fraser, R | 1 |
| Frier, BM | 1 |
| McPherson, SG | 1 |
| Scommegna, A | 1 |
| Nedoss, BR | 1 |
| Chattoraj, SC | 1 |
| Dickey, RP | 1 |
| Thompson, JP | 1 |
| Maeyama, M | 1 |
| Nakagawa, T | 1 |
| Northrop, G | 1 |
| Ditzler, J | 1 |
| Ryan, WG | 1 |
| Wilbanks, GD | 1 |
| Bachmann, R | 1 |
| Gennser, G | 1 |
| Hökfelt, B | 1 |
| Nilsson, KO | 1 |
| Sternby, NH | 1 |
| Okamoto, K | 1 |
6 reviews available for metyrapone and Complications, Pregnancy
| Article | Year |
|---|---|
[Cushing's syndrome: special issues].
Topics: Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adult; Child; Cush | 2009 |
Pregnancy-induced Cushing's syndrome in recurrent pregnancies: case report and literature review.
Topics: Adrenocorticotropic Hormone; Adult; Australia; Cushing Syndrome; Enzyme Inhibitors; Female; Humans; | 2012 |
The medical management of Cushing's syndrome during pregnancy.
Topics: Adrenalectomy; Cushing Syndrome; Female; Humans; Hydrocortisone; Ketoconazole; Metyrapone; Pre-Eclam | 2013 |
[Cushing's syndrome during pregnancy].
Topics: Adrenal Cortex Neoplasms; Adult; Anti-Inflammatory Agents; Antimetabolites; Cushing Syndrome; Dexame | 2002 |
Recurrent ACTH-independent Cushing's syndrome in multiple pregnancies and its treatment with metyrapone.
Topics: Abortion, Therapeutic; Adolescent; Adrenal Glands; Cesarean Section; Cushing Syndrome; Female; Fetal | 2001 |
Spontaneous hypertension in rats.
Topics: Adrenal Medulla; Animals; Antihypertensive Agents; Aorta; Arteries; Autonomic Agents; Body Weight; C | 1969 |
15 other studies available for metyrapone and Complications, Pregnancy
| Article | Year |
|---|---|
Maternal stress during pregnancy increases neonatal allergy susceptibility: role of glucocorticoids.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Corticosterone; Disease Susceptibility; Female; Glucocor | 2014 |
A successful case of pregnancy in a woman with ACTH-independent Cushing's syndrome treated with ketoconazole and metyrapone.
Topics: Adult; Cushing Syndrome; Drug Therapy, Combination; Female; Humans; Ketoconazole; Metyrapone; Pregna | 2017 |
[Studies with adrenostatic Su 4885 (Metopirone) in pregnancy].
Topics: Edema; Female; Ketones; Metyrapone; Pregnancy; Pregnancy Complications; Pyridines | 1963 |
METYRAPONE AND ACUTE ADRENAL INSUFFICIENCY.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Insufficiency; Arthritis; Arthritis, Rheumatoid; F | 1964 |
Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy.
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cushing Syndrome; Enzyme Inhibitors; Female; | 2006 |
Cushing's syndrome in pregnancy--treatment with metyrapone.
Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Cushing Syndrome; Female; Humans; Metyrapone; Pregnancy; Pr | 1982 |
ACTH-independent Cushing's syndrome in pregnancy with spontaneous resolution after delivery: control of the hypercortisolism with metyrapone.
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Delivery, Obstetric; Female; Humans; Hydrocort | 1993 |
Pregnancy-dependent Cushing's syndrome in three pregnancies.
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Female; Humans; Hydrocortisone; Metyrapone; Pr | 2000 |
[Diagnostic problems in Cushing's syndrome during pregnancy].
Topics: Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Female; Humans; Hydrocortisone; Metyrapone; Pr | 1976 |
Pregnancy complicated by Cushing's syndrome: potential hazard of metyrapone therapy. Case report.
Topics: Adult; Cushing Syndrome; Female; Humans; Hypertension; Metyrapone; Pregnancy; Pregnancy Complication | 1985 |
Maternal urinary estriol excretion after dehydroepiandrosterone-sulfate infusion and adrenal stimulation and suppression.
Topics: 17-Ketosteroids; Adrenal Glands; Adrenocorticotropic Hormone; Dehydroepiandrosterone; Dexamethasone; | 1968 |
Effect of ACTH and metyrapone on estriol, 17-hydroxycorticosteroid, 17-ketosteroid, pregnanediol and pregnanetriol excretion late in pregnancy.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Body Weight; Estriol | 1969 |
Effects of ACTH, metopirone and dexamethasone on maternal urinary steroid excretion in late pregnancy.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Adult; Dexamethasone; Estradiol; Estriol; Es | 1970 |
Estriol excretion profiles in narcotic-addicted pregnant women.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Age Fact | 1972 |
Steroid studies in a case of ovarian hyperluteinization with virilism in two consecutive pregnancies.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; An | 1974 |