metyrapone has been researched along with Colonic Neoplasms in 3 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ACTH content of the post mortem colonic cancer was 5." | 1.26 | Corticotropin-releasing factor-like activity in ACTH producing tumors. ( Demura, H; Demura, R; Nomura, K; Odagiri, E; Shizume, K; Suda, T; Wakabayashi, I, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Suda, T | 1 |
| Demura, H | 1 |
| Demura, R | 1 |
| Wakabayashi, I | 1 |
| Nomura, K | 1 |
| Odagiri, E | 1 |
| Shizume, K | 1 |
| Levitt, M | 1 |
| Sharma, RN | 1 |
| Faiman, C | 1 |
| Shiiki, S | 1 |
| Fuchimoto, S | 1 |
| Orita, K | 1 |
1 trial available for metyrapone and Colonic Neoplasms
| Article | Year |
|---|---|
Normal metyrapone response after 1 month of high-dose methylprednisolone in cancer patients: a phase I study.
Topics: Adenocarcinoma; Aged; Clinical Trials as Topic; Colonic Neoplasms; Cortodoxone; Female; Humans; Hydr | 1979 |
2 other studies available for metyrapone and Colonic Neoplasms
| Article | Year |
|---|---|
Corticotropin-releasing factor-like activity in ACTH producing tumors.
Topics: Adrenocorticotropic Hormone; Animals; Cell Line; Cerebral Cortex; Colonic Neoplasms; Corticotropin-R | 1977 |
A comparison of the antitumor effects of natural human tumor necrosis factors alpha and beta: the roles of arachidonic acid metabolism and intracellular cAMP.
Topics: Arachidonic Acid; Arachidonic Acids; Breast Neoplasms; Colforsin; Colonic Neoplasms; Cyclic AMP; Dex | 1990 |