metyrapone has been researched along with Chronic Primary Open Angle Glaucoma in 2 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To examine the effect of a decrease in plasma cortisol level on intraocular pressure, 14 subjects with elevated ocular pressure were given oral metyrapone tartrate (an inhibitor of adrenal cortisol biosynthesis) and a placebo in a double-masked, two-period, crossover trial." | 5.06 | Decrease of ocular pressure with oral metyrapone. A double-masked crossover trial. ( Levi, L; Schwartz, B, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schwartz, B | 2 |
| Wysocki, A | 1 |
| Qi, Y | 1 |
| Levi, L | 1 |
1 trial available for metyrapone and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Decrease of ocular pressure with oral metyrapone. A double-masked crossover trial.
Topics: Administration, Oral; Adrenocorticotropic Hormone; Aged; Cortodoxone; Double-Blind Method; Drug Eval | 1987 |
1 other study available for metyrapone and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Decreased response of plasma cortisol to intravenous metyrapone in ocular hypertension and primary open-angle glaucoma.
Topics: Aged; Enzyme Inhibitors; Female; Glaucoma, Open-Angle; Humans; Hydrocortisone; Hypothalamo-Hypophyse | 2005 |