Page last updated: 2024-10-31

metyrapone and Chemical Dependence

metyrapone has been researched along with Chemical Dependence in 7 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Goeders, NE1
Guerin, GF1
Schmoutz, CD1
Ducat, E1
Ray, B1
Bart, G1
Umemura, Y1
Varon, J1
Ho, A1
Kreek, MJ2
Ragunath, J1
Plevy, S1
Hamer, D1
Schneider, B1
Hartman, N1
Vescovi, PP1
Gerra, G1
Maninetti, L1
Pedrazzoni, M1
Michelini, M1
Pioli, G1
Girasole, G1
Caccavari, R1
Maestri, D1
Passeri, M1
Northrop, G1
Ditzler, J1
Ryan, WG1
Wilbanks, GD1
Christy, NP1
Cushman, P1
Bordier, B1
Hilton, JG1

Reviews

1 review available for metyrapone and Chemical Dependence

ArticleYear
The combination of metyrapone and oxazepam for the treatment of cocaine and other drug addictions.
    Advances in pharmacology (San Diego, Calif.), 2014, Volume: 69

    Topics: Animals; Anti-Anxiety Agents; Cocaine-Related Disorders; Humans; Metyrapone; Oxazepam; Stress, Psych

2014

Trials

1 trial available for metyrapone and Chemical Dependence

ArticleYear
Hypothalamic-pituitary-adrenal axis in methadone-treated heroin addicts.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:1

    Topics: 17-Hydroxycorticosteroids; Adult; Clinical Trials as Topic; Corticotropin-Releasing Hormone; Feedbac

1970

Other Studies

5 other studies available for metyrapone and Chemical Dependence

ArticleYear
Mu-opioid receptor A118G polymorphism in healthy volunteers affects hypothalamic-pituitary-adrenal axis adrenocorticotropic hormone stress response to metyrapone.
    Addiction biology, 2013, Volume: 18, Issue:2

    Topics: Adrenocorticotropic Hormone; Alleles; Analysis of Variance; Antimetabolites; Area Under Curve; Exons

2013
ACTH, cortisol and beta-endorphin response to metyrapone testing during chronic methadone maintenance treatment in humans.
    Neuropeptides, 1984, Volume: 5, Issue:1-3

    Topics: Adrenocorticotropic Hormone; beta-Endorphin; Endorphins; Female; Hormones; Humans; Hydrocortisone; M

1984
Metyrapone effects on beta-endorphin, ACTH and cortisol levels after chronic opiate receptor stimulation in man.
    Neuropeptides, 1990, Volume: 15, Issue:3

    Topics: Adrenocorticotropic Hormone; Adult; beta-Endorphin; Heroin Dependence; Humans; Hydrocortisone; Male;

1990
Estriol excretion profiles in narcotic-addicted pregnant women.
    American journal of obstetrics and gynecology, 1972, Volume: 112, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Age Fact

1972
The clinical significance of pituitary-adrenal suppression by exogenous corticosteroids.
    Journal of chronic diseases, 1973, Volume: 26, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Humans; Metyrapone; Pi

1973