metyrapone has been researched along with Chemical Dependence in 7 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (57.14) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goeders, NE | 1 |
| Guerin, GF | 1 |
| Schmoutz, CD | 1 |
| Ducat, E | 1 |
| Ray, B | 1 |
| Bart, G | 1 |
| Umemura, Y | 1 |
| Varon, J | 1 |
| Ho, A | 1 |
| Kreek, MJ | 2 |
| Ragunath, J | 1 |
| Plevy, S | 1 |
| Hamer, D | 1 |
| Schneider, B | 1 |
| Hartman, N | 1 |
| Vescovi, PP | 1 |
| Gerra, G | 1 |
| Maninetti, L | 1 |
| Pedrazzoni, M | 1 |
| Michelini, M | 1 |
| Pioli, G | 1 |
| Girasole, G | 1 |
| Caccavari, R | 1 |
| Maestri, D | 1 |
| Passeri, M | 1 |
| Northrop, G | 1 |
| Ditzler, J | 1 |
| Ryan, WG | 1 |
| Wilbanks, GD | 1 |
| Christy, NP | 1 |
| Cushman, P | 1 |
| Bordier, B | 1 |
| Hilton, JG | 1 |
1 review available for metyrapone and Chemical Dependence
| Article | Year |
|---|---|
The combination of metyrapone and oxazepam for the treatment of cocaine and other drug addictions.
Topics: Animals; Anti-Anxiety Agents; Cocaine-Related Disorders; Humans; Metyrapone; Oxazepam; Stress, Psych | 2014 |
1 trial available for metyrapone and Chemical Dependence
| Article | Year |
|---|---|
Hypothalamic-pituitary-adrenal axis in methadone-treated heroin addicts.
Topics: 17-Hydroxycorticosteroids; Adult; Clinical Trials as Topic; Corticotropin-Releasing Hormone; Feedbac | 1970 |
5 other studies available for metyrapone and Chemical Dependence
| Article | Year |
|---|---|
Mu-opioid receptor A118G polymorphism in healthy volunteers affects hypothalamic-pituitary-adrenal axis adrenocorticotropic hormone stress response to metyrapone.
Topics: Adrenocorticotropic Hormone; Alleles; Analysis of Variance; Antimetabolites; Area Under Curve; Exons | 2013 |
ACTH, cortisol and beta-endorphin response to metyrapone testing during chronic methadone maintenance treatment in humans.
Topics: Adrenocorticotropic Hormone; beta-Endorphin; Endorphins; Female; Hormones; Humans; Hydrocortisone; M | 1984 |
Metyrapone effects on beta-endorphin, ACTH and cortisol levels after chronic opiate receptor stimulation in man.
Topics: Adrenocorticotropic Hormone; Adult; beta-Endorphin; Heroin Dependence; Humans; Hydrocortisone; Male; | 1990 |
Estriol excretion profiles in narcotic-addicted pregnant women.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Age Fact | 1972 |
The clinical significance of pituitary-adrenal suppression by exogenous corticosteroids.
Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Humans; Metyrapone; Pi | 1973 |