metyrapone has been researched along with Central Nervous System Diseases in 6 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Central Nervous System Diseases: Diseases of any component of the brain (including the cerebral hemispheres, diencephalon, brain stem, and cerebellum) or the spinal cord.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (83.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Raubenheimer, PJ | 1 |
| Young, EA | 1 |
| Andrew, R | 1 |
| Seckl, JR | 1 |
| Rinne, UK | 1 |
| Rüedi, B | 1 |
| Wertheimer, J | 1 |
| Felber, JP | 1 |
| Vannotti, A | 1 |
| Hasui, K | 1 |
| Krieger, DT | 2 |
| Krieger, HP | 2 |
2 trials available for metyrapone and Central Nervous System Diseases
| Article | Year |
|---|---|
The role of corticosterone in human hypothalamic-pituitary-adrenal axis feedback.
Topics: Adrenocorticotropic Hormone; Adult; Aged; Analysis of Variance; Area Under Curve; Central Nervous Sy | 2006 |
Vasopressin test in central nervous system-pituitary disorders.
Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma, Chromophobe; Adrenal Glands; Adrenocorticotropic Hor | 1968 |
4 other studies available for metyrapone and Central Nervous System Diseases
| Article | Year |
|---|---|
Disturbances of plasma cortisol circadian rhythm and of cortisol-ACTH feedback mechanism in central nervous system diseases.
Topics: Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Aged; Central Nervous System Disease | 1967 |
[Diurnal variation of plasma cortisol concentration in patients with various diseases and negative feedback mechanism of the pituitary-adrenal axis].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Central Nervous Sys | 1969 |
Effects of organic brain lesions on adrenal cortical activity.
Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Aldosterone; Brain Diseases; Brain Neoplasms; Central Ner | 1966 |
Circadian variation of the plasma 17-hydroxycorticosteroids in central nervous system disease.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Brain Neoplasms; Central Nervous System Diseases; Circ | 1966 |