metyrapone has been researched along with Cardiovascular Diseases in 3 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Cardiovascular Diseases: Pathological conditions involving the CARDIOVASCULAR SYSTEM including the HEART; the BLOOD VESSELS; or the PERICARDIUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Metyrapone-treated animals developed severe hypertension with greatly elevated serum creatin phosphokinase, glucose, BUN and cholesterol levels." | 1.26 | Metyrapone-induced cardiovascular degenerative changes in non-arteriosclerotic and arteriosclerotic rats. ( Greenberg, BP; Wexler, BC, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, Q | 1 |
| Yin, L | 1 |
| Hartmann, RW | 1 |
| Durrant, LM | 1 |
| Khorram, O | 1 |
| Buchholz, JN | 1 |
| Pearce, WJ | 1 |
| Wexler, BC | 1 |
| Greenberg, BP | 1 |
3 other studies available for metyrapone and Cardiovascular Diseases
| Article | Year |
|---|---|
Aldosterone synthase inhibitors as promising treatments for mineralocorticoid dependent cardiovascular and renal diseases.
Topics: Aldosterone; Animals; Benzimidazoles; Cardiovascular Diseases; Cytochrome P-450 CYP11B2; Fadrozole; | 2014 |
Maternal food restriction modulates cerebrovascular structure and contractility in adult rat offspring: effects of metyrapone.
Topics: Age Factors; Animals; Calcium; Caloric Restriction; Cardiovascular Diseases; Cerebrovascular Circula | 2014 |
Metyrapone-induced cardiovascular degenerative changes in non-arteriosclerotic and arteriosclerotic rats.
Topics: Adrenal Glands; Animals; Arteries; Arteriosclerosis; Blood Urea Nitrogen; Body Weight; Cardiovascula | 1978 |