metyrapone has been researched along with Bronchopulmonary Dysplasia in 3 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Bronchopulmonary Dysplasia: A chronic lung disease developed after OXYGEN INHALATION THERAPY or mechanical ventilation (VENTILATION, MECHANICAL) usually occurring in certain premature infants (INFANT, PREMATURE) or newborn infants with respiratory distress syndrome (RESPIRATORY DISTRESS SYNDROME, NEWBORN). Histologically, it is characterized by the unusual abnormalities of the bronchioles, such as METAPLASIA, decrease in alveolar number, and formation of CYSTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Maternal food restriction (MFR) causes intrauterine growth restriction, a known risk factor for developing chronic lung disease." | 1.42 | Metyrapone alleviates deleterious effects of maternal food restriction on lung development and growth of rat offspring. ( Khorram, O; Li, Y; Paek, DS; Rehan, VK; Sakurai, R; Saraswat, A; Torday, JS, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Paek, DS | 1 |
| Sakurai, R | 1 |
| Saraswat, A | 1 |
| Li, Y | 1 |
| Khorram, O | 1 |
| Torday, JS | 1 |
| Rehan, VK | 1 |
| Alkalay, AL | 2 |
| Pomerance, JJ | 2 |
| Puri, AR | 1 |
| Lin, BJ | 1 |
| Vinstein, AL | 1 |
| Neufeld, ND | 1 |
| Klein, AH | 1 |
3 other studies available for metyrapone and Bronchopulmonary Dysplasia
| Article | Year |
|---|---|
Metyrapone alleviates deleterious effects of maternal food restriction on lung development and growth of rat offspring.
Topics: Age Factors; Animals; Bronchopulmonary Dysplasia; Caloric Restriction; Cell Differentiation; Cells, | 2015 |
Use of the metyrapone test for assessing pituitary-adrenal function.
Topics: Bronchopulmonary Dysplasia; Dexamethasone; Humans; Hypothalamo-Hypophyseal System; Infant, Newborn; | 1993 |
Hypothalamic-pituitary-adrenal axis function in very low birth weight infants treated with dexamethasone.
Topics: Birth Weight; Bronchopulmonary Dysplasia; Cortodoxone; Dexamethasone; Drug Administration Schedule; | 1990 |