metyrapone has been researched along with Bronchial Neoplasms in 10 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Bronchial Neoplasms: Tumors or cancer of the BRONCHI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cushing's syndrome due to bronchial carcinoid tumors that secrete adrenocorticotropin (ACTH) may be difficult to distinguish from pituitary Cushing's disease, since the responses to dexamethasone and metyrapone are sometimes similar." | 7.67 | Ectopic ACTH syndrome caused by a bronchial carcinoid tumor responsive to dexamethasone, metyrapone, and corticotropin-releasing factor. ( Abboud, C; Carey, RM; Carney, JA; Malchoff, CD; Orth, DN; Pairolero, PC, 1988) |
| "Cushing's syndrome due to bronchial carcinoid tumors that secrete adrenocorticotropin (ACTH) may be difficult to distinguish from pituitary Cushing's disease, since the responses to dexamethasone and metyrapone are sometimes similar." | 3.67 | Ectopic ACTH syndrome caused by a bronchial carcinoid tumor responsive to dexamethasone, metyrapone, and corticotropin-releasing factor. ( Abboud, C; Carey, RM; Carney, JA; Malchoff, CD; Orth, DN; Pairolero, PC, 1988) |
| " Conservative treatment with metyrapone suppressed the Cushing syndrome." | 3.66 | [Successful conservative treatment of bronchial carcinoid with Cushing's syndrome due to ectopic ACTH production]. ( Euler, HH; Herrlinger, JD; Kirmse, L; Kleine, L; Löffler, H; Müller-Hermelink, HK, 1983) |
| "Why some bronchial carcinoid tumours are responsive is unknown but it could be because of co-secretion of corticotrophin releasing factor (CRF) and/or expression of glucocorticoid receptors." | 1.29 | Glucocorticoid responsive ACTH secreting bronchial carcinoid tumours contain high concentrations of glucocorticoid receptors. ( Donald, RA; Espiner, EA; Florkowski, CM; Lewis, JG; Wittert, GA, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| SOBOTA, JT | 1 |
| REED, RJ | 1 |
| Herrlinger, JD | 1 |
| Euler, HH | 1 |
| Kleine, L | 1 |
| Kirmse, L | 1 |
| Müller-Hermelink, HK | 1 |
| Löffler, H | 1 |
| Florkowski, CM | 1 |
| Wittert, GA | 1 |
| Lewis, JG | 1 |
| Donald, RA | 1 |
| Espiner, EA | 1 |
| Malchoff, CD | 1 |
| Orth, DN | 1 |
| Abboud, C | 1 |
| Carney, JA | 1 |
| Pairolero, PC | 1 |
| Carey, RM | 1 |
| Schteingart, DE | 1 |
| Lloyd, RV | 1 |
| Akil, H | 1 |
| Chandler, WF | 1 |
| Ibarra-Perez, G | 1 |
| Rosen, SG | 1 |
| Ogletree, R | 1 |
| Strott, CA | 1 |
| Nugent, CA | 1 |
| Tyler, FH | 1 |
| Materazzi, F | 1 |
| Jones, JE | 1 |
| Shane, SR | 1 |
| Gilbert, E | 1 |
| Flink, EB | 1 |
| Brun, J | 1 |
| Revol, A | 1 |
| Queneau, P | 1 |
| Vingerhoeds, AC | 1 |
| Thijssen, JH | 1 |
| Schwarz, F | 1 |
10 other studies available for metyrapone and Bronchial Neoplasms
| Article | Year |
|---|---|
MULTIPLE BRONCHIAL ADENOMAS, CUSHING'S SYNDROME AND HYPOKALEMIC ALKALOSIS. REPORT OF A CASE.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenalectomy; Adrenocorticotropic Hormone; Alk | 1964 |
[Successful conservative treatment of bronchial carcinoid with Cushing's syndrome due to ectopic ACTH production].
Topics: ACTH Syndrome, Ectopic; Bronchial Neoplasms; Carcinoid Tumor; Cushing Syndrome; Cyclophosphamide; Do | 1983 |
Glucocorticoid responsive ACTH secreting bronchial carcinoid tumours contain high concentrations of glucocorticoid receptors.
Topics: ACTH Syndrome, Ectopic; Adolescent; Adult; Bronchial Neoplasms; Carcinoid Tumor; Corticotropin-Relea | 1994 |
Ectopic ACTH syndrome caused by a bronchial carcinoid tumor responsive to dexamethasone, metyrapone, and corticotropin-releasing factor.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Bronchial Neoplasms; Carcinoid Tumor; Co | 1988 |
Cushing's syndrome secondary to ectopic corticotropin-releasing hormone-adrenocorticotropin secretion.
Topics: ACTH Syndrome, Ectopic; Bronchial Neoplasms; Carcinoid Tumor; Corticotropin-Releasing Hormone; Cushi | 1986 |
Cushing's syndrome caused by bronchial adenomas.
Topics: Adenoma; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Biological Assay; Bronchial Neoplasms; C | 1968 |
[Reichstein's S substance in humans].
Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; A | 1966 |
Cushing's syndrome induced by the ectopic production of ACTH by a bronchial carcinoid.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Aged; Bronchial Neoplasms; | 1969 |
[Broncho-pulmonary cancer with true or degraded hypercorticism].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocortical Hyperfunction; Adrenocorticotropic Hormon | 1969 |
Detection of an ACTH-secreting bronchial carcinoid tumour eighteen months after adrenalectomy for Cushing's syndrome.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Bronc | 1971 |