Page last updated: 2024-10-31

metyrapone and Brain Neoplasms

metyrapone has been researched along with Brain Neoplasms in 18 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-199016 (88.89)18.7374
1990's2 (11.11)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KRIEGER, DT4
KOLODNY, H1
KRIEGER, HP4
Fujiwara, I1
Igarashi, Y1
Ogawa, E1
Shankar, RR1
Jakacki, RI1
Haider, A1
Lee, MW1
Pescovitz, OH1
Khomitskaia, LF1
Razumovskaia-Molukalo, LP1
Bezverkhaia, TP1
Afanasenkov, MI1
Martin, MM1
Mayama, T1
Tucci, JR1
Espiner, EA1
Jagger, PI1
Lauler, DP1
Thorn, GW1
Few, JD1
Bonanni, G1
Lundberg, PO2
Wide, L1
Uozumi, T1
Mori, S1
Watanabe, M1
Takimoto, N1
Mogami, H1
Brisman, R1
Chutorian, AM1
Fishman, MA1
Peake, GT1
Quabbe, HJ1
Glick, S1
Silverberg, A1
Hugosson, R1

Trials

1 trial available for metyrapone and Brain Neoplasms

ArticleYear
A comparison of pituitary-adrenal responses to corticotropin-releasing hormone, hypoglycaemia and metyrapone in children with brain tumours and growth hormone deficiency.
    European journal of pediatrics, 1995, Volume: 154, Issue:9

    Topics: Adolescent; Adrenocorticotropic Hormone; Brain Neoplasms; Child; Child, Preschool; Corticotropin-Rel

1995

Other Studies

17 other studies available for metyrapone and Brain Neoplasms

ArticleYear
METHOPYRAPONE TESTS IN HYPOTHALAMIC-PITUITARY DISEASE.
    The Journal of clinical endocrinology and metabolism, 1964, Volume: 24

    Topics: Adrenocorticotropic Hormone; Brain Diseases; Brain Neoplasms; Diagnosis; Humans; Hypothalamic Diseas

1964
Testing the hypothalamic-pituitary-adrenal axis in survivors of childhood brain and skull-based tumors.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:6

    Topics: Adrenocorticotropic Hormone; Brain Neoplasms; Child, Preschool; Glucocorticoids; Humans; Hydrocortis

1997
[State of the central regulation of glucocorticoid function of the adrenals in brain tumors].
    Problemy endokrinologii, 1976, Volume: 22, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Brain Neo

1976
Coexisting anterior pituitary and neurohypophyseal insufficiency. A syndrome with diagnostic implication.
    Archives of internal medicine, 1969, Volume: 123, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Biopsy;

1969
[Clinical studies on the adrenocorticotropic hormone. II. Studies on the mechanism of pituitary corticotropin secretion with synthetic lysine vasopressin].
    Nihon Naibunpi Gakkai zasshi, 1968, Jan-20, Volume: 43, Issue:10

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Brain Neoplasms; Ci

1968
Vasopressin in the evaluation of pituitary-adrenal function.
    Annals of internal medicine, 1968, Volume: 69, Issue:2

    Topics: Acromegaly; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Anorex

1968
A simple method for the separate estimation of 11-deoxy and 11-oxygenated 17-hydroxycortico-steroids in human urine.
    The Journal of endocrinology, 1968, Volume: 41, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adr

1968
[Evaluation of the pituitary ACTH reserve in patients irradiated for cerebral neoplasms].
    Nuntius radiologicus, 1968, Volume: 34, Issue:5

    Topics: Acromegaly; Adrenocorticotropic Hormone; Adult; Astrocytoma; Brain Neoplasms; Cushing Syndrome; Fema

1968
The response to TRH, LH-RH, metyrapone and vasopressin in patients with hypothalamo-pituitary disorders.
    European journal of clinical investigation, 1973, Volume: 3, Issue:1

    Topics: Acromegaly; Adenoma, Acidophil; Adenoma, Chromophobe; Adult; Brain Neoplasms; Craniopharyngioma; Dia

1973
[Endocrinological evaluation of sellar and suprasellar tumor cases --the first report-- on preoperative pituitary function (author's transl)].
    No shinkei geka. Neurological surgery, 1974, Volume: 2, Issue:5

    Topics: Adenoma; Adolescent; Adrenocorticotropic Hormone; Adult; Brain Neoplasms; Child; Chordoma; Craniopha

1974
Inappropriate ADH secretion with unique features in a child with a hypothalamic glioma.
    Transactions of the American Neurological Association, 1969, Volume: 94

    Topics: Astrocytoma; Brain Neoplasms; Child; Diet, Sodium-Restricted; Electromyography; Humans; Hyponatremia

1969
Paradoxical growth in a patient with the diencephalic syndrome.
    Pediatrics, 1970, Volume: 45, Issue:6

    Topics: Arginine; Brain Neoplasms; Child; Child, Preschool; Diencephalon; Emaciation; Glioma; Glucose; Growt

1970
Plasma growth hormone response to vasopressin: comparison with saline infusion in normal subjects and with insulin-induced hypoglycaemia in patients with intra- and suprasell tumours.
    Acta endocrinologica, 1970, Volume: 63, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Blood Glucose; Brain Neoplasms; Female; Growth Hormone

1970
A comparative study of endocrine tests in hypothalamic disease. Circadian periodicity of plasma 11-OHCS levels, plama 11-OHCS and growth hormone response to insulin hypoglycemia and metyrapone responsiveness.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:11

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Arachnoiditis; Brain Neoplasms; Cerebral Ventricle

1968
Effects of organic brain lesions on adrenal cortical activity.
    Research publications - Association for Research in Nervous and Mental Disease, 1966, Volume: 43

    Topics: 17-Hydroxycorticosteroids; Adrenal Glands; Aldosterone; Brain Diseases; Brain Neoplasms; Central Ner

1966
Circadian variation of the plasma 17-hydroxycorticosteroids in central nervous system disease.
    The Journal of clinical endocrinology and metabolism, 1966, Volume: 26, Issue:9

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adult; Brain Neoplasms; Central Nervous System Diseases; Circ

1966
Application of the metopirone test to tumors in the region of the sella turcica.
    Journal of neurosurgery, 1966, Volume: 25, Issue:5

    Topics: Acromegaly; Adenoma, Chromophobe; Adolescent; Adult; Aged; Brain Neoplasms; Child; Female; Humans; M

1966