metyrapone has been researched along with Brain Injuries in 7 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
Brain Injuries: Acute and chronic (see also BRAIN INJURIES, CHRONIC) injuries to the brain, including the cerebral hemispheres, CEREBELLUM, and BRAIN STEM. Clinical manifestations depend on the nature of injury. Diffuse trauma to the brain is frequently associated with DIFFUSE AXONAL INJURY or COMA, POST-TRAUMATIC. Localized injuries may be associated with NEUROBEHAVIORAL MANIFESTATIONS; HEMIPARESIS, or other focal neurologic deficits.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (71.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Welling, LC | 1 |
| Figueiredo, EG | 1 |
| de Andrade, AF | 1 |
| Hellmich, HL | 1 |
| Rojo, DR | 1 |
| Micci, MA | 1 |
| Sell, SL | 1 |
| Boone, DR | 1 |
| Crookshanks, JM | 1 |
| DeWitt, DS | 1 |
| Masel, BE | 1 |
| Prough, DS | 1 |
| Stevenson, C | 1 |
| Santelices, R | 1 |
| Martin, L | 1 |
| Asenjo, A | 1 |
| Kawakami, M | 1 |
| Koshino, T | 1 |
| Hattori, Y | 1 |
| Rinne, UK | 1 |
| Bouzarth, WF | 1 |
| Shenkin, HA | 1 |
| Feldman, W | 1 |
| Sakashita, K | 1 |
| Yokomi, Y | 1 |
7 other studies available for metyrapone and Brain Injuries
| Article | Year |
|---|---|
Translation experiments in traumatic brain injury … is it time to renew pharmacologic therapy?
Topics: Animals; Brain Injuries; Carbenoxolone; Humans; Male; Metyrapone; Signal Transduction | 2013 |
Pathway analysis reveals common pro-survival mechanisms of metyrapone and carbenoxolone after traumatic brain injury.
Topics: Animals; Brain Injuries; Carbenoxolone; Cell Death; Cell Survival; Gene Expression Regulation; Hippo | 2013 |
[Evaluation of the thyroid and hypothalamo-hypophyseal-adrenal system in patients with severe craniocerebral injuries].
Topics: 17-Hydroxycorticosteroids; Blood Glucose; Brain Injuries; Humans; Hydrocortisone; Hypothalamo-Hypoph | 1971 |
Changes in the EEG of the hypothalamus and limbic system after administration of ACTH, SU-4885 and ACH in rabbits with special reference to neurohumoral feedback regulation of pituitary-adrenal system.
Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Brain; Brain Injuries; Cerebral Cortex; Electr | 1966 |
Corticotrophin secretion in patients with head injuries examined by the metopirone test.
Topics: Adrenocorticotropic Hormone; Adult; Brain Injuries; Cerebral Ventriculography; Coma; Female; Humans; | 1966 |
Adrenocortical response to craniocerebral trauma.
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic | 1968 |
[Vertigo caused by SU 4885 (drug used in the hypophyseal function test)].
Topics: Adult; Brain Injuries; Electrooculography; Female; Humans; Male; Metyrapone; Middle Aged; Pituitary | 1971 |