Page last updated: 2024-10-31

metyrapone and Body Weight

metyrapone has been researched along with Body Weight in 69 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Body Weight: The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.

Research Excerpts

ExcerptRelevanceReference
"Metyrapone (MT) has been used clinically to decrease glucocorticoid levels in human and animal studies."5.36Evidence that metyrapone in the presence of inflammation modulates cytokine mRNA expression. ( Andersen, ML; Benatti, BB; Casati, MZ; Nociti, FH; Peruzzo, DC; Tufik, S, 2010)
"This study has evaluated the relationship between the antiglucocorticoid effect of RU 486 and its pharmacokinetics in seven female mongrel dogs (weight 21-30 kg), all of which had appropriate responses to insulin-induced hypoglycemia and metyrapone."3.68The divergent effect of RU 486 on adrenal function in the dog is related to differences in its pharmacokinetics. ( Heikinheimo, O; Spitz, IM; Wade, CE, 1993)
"The disturbance of corticosteroids balance of female rats on the 16 and 18 days of pregnancy by injections of exogenous corticosterone or methopyrone--blocker of endogenous hormone formation--decreased both body weight and activity of the rate-limiting catecholamine synthesising enzyme--tyrosine hydroxylase (TH) in the stem half of the 21 day fetal brain."3.68[The catecholamine system in rat fetal brain with a disrupted corticosteroid balance]. ( Dygalo, NN; Kalinina, TS; Naumenko, EV, 1991)
"Fetal and neonatal hypoadrenalism was induced by treating rat mothers with metyrapone from day 12 of pregnancy to day 7 postnatally."3.68Perinatal hypoadrenalism in the rat does not alter glucose tolerance and insulin secretory response to glucose. ( Eriksson, UJ; Karlsson, MG; Swenne, I, 1990)
" A regimen of twice daily metyrapone injections (10 mg/100 gm body weight), results in marked depression of serum corticosterone in pregnant and in fetal rats without surgical trauma and stress."3.68Fetal and maternal levels of corticosterone and ACTH after pharmacological adrenalectomy. ( Baram, TZ; Schultz, L, 1990)
"Metyrapone (MT) has been used clinically to decrease glucocorticoid levels in human and animal studies."1.36Evidence that metyrapone in the presence of inflammation modulates cytokine mRNA expression. ( Andersen, ML; Benatti, BB; Casati, MZ; Nociti, FH; Peruzzo, DC; Tufik, S, 2010)
"Fenfluramine (FEN) is a substituted amphetamine known for its anorectic effects, without the stimulatory or abuse potential associated with other amphetamine derivatives."1.32Metyrapone attenuates the sequential learning deficits but not monoamine depletions following d,l-fenfluramine administration to adult rats. ( Blankenmeyer, TL; Brown-Strittholt, CA; Gudelsky, GA; Skelton, MR; Vorhees, CV; Williams, MT, 2004)
"The sensitivity of tumors to cyclophosphamide (CPA) and other anticancer prodrugs can be substantially enhanced by transduction of tumors with a prodrug-activating mammalian cytochrome P450 (CYP) enzyme in combination with the flavoenzyme P450 reductase."1.31Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors. ( Huang, Z; Waxman, DJ, 2001)
"Pretreatment with metyrapone (a corticosterone synthesis inhibitor 150 mg/kg i."1.27Central serotonergic responses and behavioural adaptation to repeated immobilisation: the effect of the corticosterone synthesis inhibitor metyrapone. ( Curzon, G; Dickinson, SL; Kennett, GA, 1985)
"The Metyrapone-treated animals developed severe hypertension with greatly elevated serum creatin phosphokinase, glucose, BUN and cholesterol levels."1.26Metyrapone-induced cardiovascular degenerative changes in non-arteriosclerotic and arteriosclerotic rats. ( Greenberg, BP; Wexler, BC, 1978)
"Three children with Fanconi's anemia belonging to a family where 6 children had the disease were investigated."1.25Fanconi's anemia. II. Are multiple endocrine insufficiencies a substantial part of the disease? ( Prindull, G; Stubbe, P, 1975)
"The effects of chronic administration of metyrapone, a specific adrenal 11beta-hydroxylase inhibitor, were examined on the reproductive organs of house mice."1.25Effects of metyrapone on reproductive organs of house mice (38533). ( Blue, LR; McKinney, RD; Pasley, JN, 1975)
"Medroxyprogesterone (MPA) is a progestin with no clinically detectable estrogenic and androgenic properties used in the treatment of sexual precocity."1.25Adverse effects of large doses of medroxyprogesterone (MPA) in idiopathic isosexual precocity. ( French, FS; Richman, RA; Underwood, LE; Van Wyk, JJ, 1971)

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-199055 (79.71)18.7374
1990's8 (11.59)18.2507
2000's5 (7.25)29.6817
2010's1 (1.45)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Peruzzo, DC1
Benatti, BB1
Andersen, ML1
Tufik, S1
Casati, MZ1
Nociti, FH1
Strausbaugh, HJ1
Green, PG1
Dallman, MF1
Levine, JD1
FISHER, DA1
MORRIS, MD1
Skelton, MR1
Blankenmeyer, TL1
Gudelsky, GA1
Brown-Strittholt, CA1
Vorhees, CV1
Williams, MT1
Coppes, JC1
Bradley, EL1
Birrenkott, GP1
Ezzat, AR1
Zulkifli, I1
Dunnington, EA1
Gross, WB1
Siegel, PB1
Spitz, IM1
Heikinheimo, O1
Wade, CE1
Andersson, SE1
Källström, L1
Malm, M1
Miller-Larsson, A1
Axelsson, B1
Chen, L1
Waxman, DJ2
Chen, D1
Kufe, DW1
Takeshita, N1
Yoshino, T1
Mutoh, S1
Valli, G1
Sudha, S1
Ravi Sankar, B1
Govindarajulu, P1
Srinivasan, N1
Huang, Z1
Culbert, J1
Wells, JW1
Wexler, BC1
Greenberg, BP1
Betz, TW2
Nagler, P1
Stubbe, P1
Prindull, G1
Pasley, JN2
McKinney, RD1
Blue, LR1
Cooper, DY1
Schleyer, H1
Thomas, JH1
Vars, HM1
Rosenthal, O1
Iwasaki, K1
Shiraga, T1
Matsuda, H1
Noda, K1
Yamazoe, Y1
Nagata, K1
Yasumori, T1
Ozawa, S1
Shimada, M1
Murayama, N1
Dygalo, NN1
Kalinina, TS1
Naumenko, EV1
Karlsson, MG1
Eriksson, UJ1
Swenne, I1
Baram, TZ1
Schultz, L1
Schreiber, V1
Kapitola, J1
Kölbel, F1
Kennett, GA1
Dickinson, SL1
Curzon, G1
Roe, TF1
Kogut, MD1
Gaunt, R1
Gisoldi, E1
Herkner, J1
Howie, N1
Renzi, AA1
Michaels, RH1
Kenny, FM4
Tucci, JR1
Espiner, EA1
Jagger, PI1
Lauler, DP1
Brackett, NC1
Koppel, M1
Randall, RE1
Nixon, WP1
Kuo, B1
Zaino, E1
Roginsky, MS1
Weber, A1
Gossmann, HH1
Ott, JE1
Robinson, A1
Dickey, RP1
Thompson, JP1
Soyka, LF1
Bode, HH1
Crawford, JD1
Flynn, FJ1
Künzel, W1
Lauritzen, C1
Callard, IP3
Willard, E1
Jones, IC1
Dupouy, JP2
Richman, RA1
Underwood, LE1
French, FS1
Van Wyk, JJ1
Daugherty, DR1
Youlton, R1
Riesco, J1
Litvak, J1
Zlatar, N1
Harada, Y1
Okada, Y1
Hikita, T1
Ninomiya, T1
Ishihara, Y1
Mendilaharzu, H1
Gregory, T1
Gardner, LI1
Okamoto, K1
Dixit, VP1
Arya, M1
Lohiya, NK1
Parvez, H1
Roffi, J1
Parvez, S1
Danowski, TS2
Livstone, E1
Gonzales, AR1
Jung, Y1
Khurana, RC1
Clary, JJ2
Stokinger, HE2
Hulan, HW1
Henning, W1
Möllmann, H1
Kindler, J1
Reisch, J1
Alfes, H1
Ferrari, E1
Bossolo, PA1
Braschi, A1
Crosti, C1
Sizonenko, PC1
Doret, AM1
Riondel, AM1
Paunier, L1
Abe, T1
Shimada, S1
Osako, R1
Nilsson, KO1
Hökfelt, B1
Suzuki, Y1
Macmillan, DR1
Kim, CB1
Weisskopf, B1
Hopper, CR1
Haim, S1
Benderly, A1
Shafrir, A1
Levy, J1
Colby, HD1
Skelton, FR1
Brownie, AC1
Tuft, L1
Marks, AD1
Channick, BJ1
Van Nostrand, DM1
Nicoloff, DM2
Van Nostrand, D1
Iturzaeta, NF1
Mintz, D1
Drash, A1
Garces, LY1
Susen, A1
Askari, HA1
Fregly, MJ1
Sabeh, G1
Alley, RA1
Robbins, TJ1
Narduzzi, JV1

Reviews

2 reviews available for metyrapone and Body Weight

ArticleYear
Cerebral gigantism.
    American journal of diseases of children (1960), 1969, Volume: 117, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Age Determination by Skeleton; Anthropometry; Body Heigh

1969
Spontaneous hypertension in rats.
    International review of experimental pathology, 1969, Volume: 7

    Topics: Adrenal Medulla; Animals; Antihypertensive Agents; Aorta; Arteries; Autonomic Agents; Body Weight; C

1969

Trials

2 trials available for metyrapone and Body Weight

ArticleYear
The effect of metyrapone on aldosterone secretion in man.
    Acta endocrinologica, 1967, Volume: 56, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Body We

1967
Effectiveness of long-term human growth hormone therapy for short stature in children with growth hormone deficiency.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Age Determination by Skeleton; Antibody Form

1970

Other Studies

65 other studies available for metyrapone and Body Weight

ArticleYear
Evidence that metyrapone in the presence of inflammation modulates cytokine mRNA expression.
    Cytokine, 2010, Volume: 52, Issue:3

    Topics: Animals; Base Sequence; Biomarkers; Body Weight; Cytokines; DNA Primers; Gene Expression Profiling;

2010
Repeated, non-habituating stress suppresses inflammatory plasma extravasation by a novel, sympathoadrenal dependent mechanism.
    The European journal of neuroscience, 2003, Volume: 17, Issue:4

    Topics: Adrenal Medulla; Adrenalectomy; Analysis of Variance; Animals; Body Weight; Bradykinin; Capillary Pe

2003
IDIOPATHIC EDEMA ND HYPERALDOSTERONURIA: POSTURAL VENOUS PLASMA POOLING.
    Pediatrics, 1965, Volume: 35

    Topics: Adolescent; Aldosterone; Angiotensins; Blood Pressure; Body Weight; Drug Therapy; Edema; Ephedrine;

1965
Metyrapone attenuates the sequential learning deficits but not monoamine depletions following d,l-fenfluramine administration to adult rats.
    Synapse (New York, N.Y.), 2004, Dec-15, Volume: 54, Issue:4

    Topics: Adrenal Glands; Age Factors; Animals; Biogenic Monoamines; Body Temperature; Body Weight; Enzyme Inh

2004
Serum ACTH and adrenal histology in reproductively inhibited male prairie deermice (Peromyscus maniculatus bairdi).
    Comparative biochemistry and physiology. A, Comparative physiology, 1984, Volume: 78, Issue:2

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Body Weight; Glucocorticoids; Male; Metyrapone

1984
Response of broilers and capons to heat stress following adrenal manipulation.
    Poultry science, 1983, Volume: 62, Issue:4

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Animals; Body Weight; Castration; Chickens; Female; Hot

1983
Inhibition of adrenal steroidogenesis, food restriction and acclimation to high ambient temperatures in chickens.
    British poultry science, 1994, Volume: 35, Issue:3

    Topics: Acclimatization; Adrenal Cortex; Animal Feed; Animals; Body Weight; Chickens; Diet, Reducing; Fastin

1994
The divergent effect of RU 486 on adrenal function in the dog is related to differences in its pharmacokinetics.
    Acta endocrinologica, 1993, Volume: 128, Issue:5

    Topics: Administration, Oral; Adrenal Cortex; Adrenocorticotropic Hormone; Analysis of Variance; Animals; Bl

1993
Inhibition of nitric oxide synthase reduces Sephadex-induced oedema formation in the rat lung: dependence on intact adrenal function.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1995, Volume: 44, Issue:10

    Topics: Adrenal Glands; Adrenalectomy; Animals; Arginine; Body Weight; Corticosterone; Dextrans; Enzyme Inhi

1995
Sensitization of human breast cancer cells to cyclophosphamide and ifosfamide by transfer of a liver cytochrome P450 gene.
    Cancer research, 1996, Mar-15, Volume: 56, Issue:6

    Topics: Adenoviridae; Animals; Antineoplastic Agents, Alkylating; Body Weight; Breast Neoplasms; Cell Cycle;

1996
Possible involvement of corticosterone in bone loss of genetically diabetic db/db mice.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 2000, Volume: 32, Issue:4

    Topics: Animals; Body Weight; Bone Density; Bone Diseases, Metabolic; Calcium; Corticosterone; Diabetes Mell

2000
Altered corticosterone status impairs steroidogenesis in the granulosa and thecal cells of Wistar rats.
    The Journal of steroid biochemistry and molecular biology, 2000, Volume: 73, Issue:3-4

    Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Body Weight; Corticosterone; Estradiol; Estrus; Female; F

2000
Modulation of cyclophosphamide-based cytochrome P450 gene therapy using liver P450 inhibitors.
    Cancer gene therapy, 2001, Volume: 8, Issue:6

    Topics: Animals; Antineoplastic Agents, Alkylating; Body Weight; Combined Modality Therapy; Cyclophosphamide

2001
Aspects of the adrenal function in the domestic fowl.
    The Journal of endocrinology, 1975, Volume: 65, Issue:3

    Topics: Adrenal Cortex Function Tests; Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Animals;

1975
Metyrapone-induced cardiovascular degenerative changes in non-arteriosclerotic and arteriosclerotic rats.
    British journal of experimental pathology, 1978, Volume: 59, Issue:1

    Topics: Adrenal Glands; Animals; Arteries; Arteriosclerosis; Blood Urea Nitrogen; Body Weight; Cardiovascula

1978
On possible involvement of adrenocorticoids in chicken spleen development.
    Revue canadienne de biologie, 1978, Volume: 37, Issue:3

    Topics: Animals; Body Weight; Chick Embryo; Corticosterone; Glucocorticoids; Metyrapone; Mixed Function Oxyg

1978
Fanconi's anemia. II. Are multiple endocrine insufficiencies a substantial part of the disease?
    Acta paediatrica Scandinavica, 1975, Volume: 64, Issue:6

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Anemia, Aplastic; Arginine; Blood Glucose; Body Height;

1975
Effects of metyrapone on reproductive organs of house mice (38533).
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1975, Volume: 148, Issue:2

    Topics: Adrenal Glands; Age Factors; Animals; Body Weight; Female; Genitalia; Male; Metyrapone; Mice; Ovary;

1975
Comparison of the induction course, biophysical chemical interactions and photochemical action spectra of phenobarbital and 3-methylcholanthrene induce hepatic microsomal P-450.
    Advances in experimental medicine and biology, 1975, Volume: 58, Issue:00

    Topics: Aniline Compounds; Animals; Biotransformation; Body Weight; Carbon Monoxide; Codeine; Cytochrome P-4

1975
Effect of repeated oral doses of a novel immunosuppressive macrolide lactone on hepatic mixed-function oxidase system in the rat. Comparative study with ciclosporin.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:3

    Topics: Animals; Body Weight; Chromatography, High Pressure Liquid; Cyclosporine; Immunosuppressive Agents;

1992
[The catecholamine system in rat fetal brain with a disrupted corticosteroid balance].
    Biulleten' eksperimental'noi biologii i meditsiny, 1991, Volume: 112, Issue:10

    Topics: Adrenal Cortex Hormones; Animals; Body Weight; Brain; Catecholamines; Corticosterone; DNA; Female; F

1991
Perinatal hypoadrenalism in the rat does not alter glucose tolerance and insulin secretory response to glucose.
    Upsala journal of medical sciences, 1990, Volume: 95, Issue:2

    Topics: Adrenal Insufficiency; Animals; Animals, Newborn; Body Weight; Corticosterone; Female; Fetus; Glucos

1990
Fetal and maternal levels of corticosterone and ACTH after pharmacological adrenalectomy.
    Life sciences, 1990, Volume: 47, Issue:6

    Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Body Weight; Corticosterone; Fe

1990
Metyrapone block of thyroid-induced cardiomegaly.
    Physiologia Bohemoslovaca, 1988, Volume: 37, Issue:4

    Topics: Adrenal Glands; Animals; Blood Pressure; Body Weight; Cardiomegaly; Eating; Hypertrophy; Male; Metyr

1988
Central serotonergic responses and behavioural adaptation to repeated immobilisation: the effect of the corticosterone synthesis inhibitor metyrapone.
    European journal of pharmacology, 1985, Dec-17, Volume: 119, Issue:3

    Topics: Adaptation, Physiological; Animals; Behavior, Animal; Body Weight; Corticosterone; Disease Models, A

1985
Hypopituitarism and ketotic hypoglycemia.
    American journal of diseases of children (1960), 1971, Volume: 121, Issue:4

    Topics: Acetone; Acidosis; Arginine; Body Height; Body Weight; Child; Fatty Acids, Nonesterified; Female; Gl

1971
Sodium retention after adrenal enucleation: drug and salt appetite studies.
    Endocrinology, 1968, Volume: 83, Issue:5

    Topics: Adrenal Glands; Adrenal Medulla; Adrenalectomy; Aminoglutethimide; Animals; Appetite; Body Weight; D

1968
Postnatal growth retardation in congenital rubella.
    Pediatrics, 1969, Volume: 43, Issue:2

    Topics: 17-Hydroxycorticosteroids; Body Height; Body Weight; Cephalometry; Child, Preschool; Female; Gestati

1969
Hyperplasia of the juxtaglomerular complex with secondary aldosteronism without hypertension (Bartter's syndrome).
    The American journal of medicine, 1968, Volume: 44, Issue:5

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Aldosterone; Ammonium Chloride; Angiotensin II; Bicarb

1968
Endocrine function in thalassemia major.
    The Journal of clinical endocrinology and metabolism, 1968, Volume: 28, Issue:6

    Topics: 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Age Determination by Skeleton; Body Height; Body

1968
[Endoccinological changes as a result of obesity in juveniles].
    Der Internist, 1968, Volume: 9, Issue:4

    Topics: Adolescent; Adrenocorticotropic Hormone; Age Factors; Blood Glucose; Body Height; Body Weight; Cushi

1968
Effect of ACTH and metyrapone on estriol, 17-hydroxycorticosteroid, 17-ketosteroid, pregnanediol and pregnanetriol excretion late in pregnancy.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Body Weight; Estriol

1969
[Analytical studies of steroid hormones in hyperemesis gravidarum].
    Endokrinologie, 1969, Volume: 54, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Body Weight; Chorion

1969
Effects of intrahypothalamic betamethazone implants on adrenal function in male sceloporus cyanogenys.
    General and comparative endocrinology, 1969, Volume: 13, Issue:3

    Topics: Adrenal Glands; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Animals; Betamethasone; B

1969
The effect of hypothalamic lesions and hypophysectomy on adrenal weight in Sceloporus cyanogenys.
    General and comparative endocrinology, 1971, Volume: 17, Issue:1

    Topics: Adrenal Glands; Adrenocorticotropic Hormone; Animals; Body Weight; Gonads; Hypophysectomy; Hypothala

1971
[Response of the hypothalamo-hypophyseal complex of the rat fetus to a blocking of corticosteroid biosynthesis by metopirone. Infleunce of cortisol].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1971, Sep-13, Volume: 273, Issue:11

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Age Factors; Animals; Body Wei

1971
Adverse effects of large doses of medroxyprogesterone (MPA) in idiopathic isosexual precocity.
    The Journal of pediatrics, 1971, Volume: 79, Issue:6

    Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Body Height; Body Weight; Bone D

1971
Plasma corticosterone levels in the male iguanid lizard Sceloporus cyanogenys under various physiological conditions.
    General and comparative endocrinology, 1972, Volume: 19, Issue:1

    Topics: Adrenal Glands; Adrenalectomy; Adrenocorticotropic Hormone; Aminoglutethimide; Animals; Body Weight;

1972
Serum growth hormone and growth activity in children and adolescents with present or past malnutrition.
    The American journal of clinical nutrition, 1972, Volume: 25, Issue:11

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Arginine; Body Height; Bo

1972
Comparison of growth acceleration of pituitary dwarfs treated with anabolic steroid and thyroid hormone with normal growth spurt.
    Acta endocrinologica, 1973, Volume: 74, Issue:2

    Topics: Adolescent; Adult; Age Determination by Skeleton; Body Height; Body Weight; Child; Dwarfism, Pituita

1973
Iatrogenic Cushing's disease in a boy after misdiagnosis of salt-losing virilizing adrenal hyperplasia: impaired metyrapone response with failure of catch-up growth.
    The Journal of pediatrics, 1973, Volume: 83, Issue:1

    Topics: 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenal Insufficiency; Adrenocorticotropic Hormone

1973
Use of corticosteroids.
    Southern medical journal, 1974, Volume: 67, Issue:11

    Topics: Addison Disease; Administration, Oral; Adolescent; Adrenocortical Hyperfunction; Age Factors; Asthma

1974
Effects of metyrapone on reproductive organs of the meadow vole, Microtus pennsylvanicus.
    Journal of reproduction and fertility, 1974, Volume: 40, Issue:2

    Topics: Adrenal Glands; Animals; Body Weight; Female; Genitalia; Injections, Intraperitoneal; Kidney; Male;

1974
Sites of the negative feedback action of corticosteroids on the hypothalamo-hypophisial system of the rat fetus.
    Neuroendocrinology, 1974, Volume: 16, Issue:3-4

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Binding Sites; Body Weight; Corticosterone; Desoxy

1974
Effect of metopiron (SU-4885, Ciba) on the female genital tract of gerbil (Meriones hurrianae) and hedgehog (Hemiechinus auritus collaris).
    Acta anatomica, 1974, Volume: 90, Issue:4

    Topics: Animals; Body Weight; Corpus Luteum; Depression, Chemical; Female; Genitalia, Female; Gerbillinae; H

1974
[Prolonged pregnancy in rats treated with metopirone].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1972, Jan-10, Volume: 274, Issue:2

    Topics: Adrenal Cortex Hormones; Animals; Body Weight; Female; Fetus; Labor, Obstetric; Metyrapone; Pregnanc

1972
Fractional and partial hypopituitarism in anorexia nervosa.
    Hormones, 1972, Volume: 3, Issue:2

    Topics: 11-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adult; Amenorrhea;

1972
The mechanism of delayed biologic response following beryllium exposure.
    Journal of occupational medicine. : official publication of the Industrial Medical Association, 1973, Volume: 15, Issue:3

    Topics: Adrenal Insufficiency; Adrenalectomy; Animals; Beryllium; Body Weight; Bone and Bones; Chemical and

1973
Effects of metopirone on duodenal differentiation and yolk sac retraction in chick embryos.
    Experientia, 1973, Feb-15, Volume: 29, Issue:2

    Topics: Alkaline Phosphatase; Animals; Body Weight; Chick Embryo; Duodenum; Female; Metyrapone; Morphogenesi

1973
[Influence of synthetic glucocorticoids and of metopirone on ketosteroid-containing cells of the postnatal rabbit thymus (author's transl)].
    Zeitschrift fur Zellforschung und mikroskopische Anatomie (Vienna, Austria : 1948), 1973, Volume: 143, Issue:1

    Topics: Adrenalectomy; Age Factors; Animals; Animals, Newborn; Betamethasone; Body Weight; Glucocorticoids;

1973
[Chrono-regulation and function of the hypothalamo-hypophyseal-adrenal system in anorexia nervosa].
    Folia endocrinologica, 1973, Volume: 26, Issue:5

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adult; Amenorrhea; Anorexia Nervosa; Body We

1973
Cushing's syndrome due to bilateral adrenal cortical hyperplasia in a 13-year old girl: successful treatment with op'DDD'.
    Helvetica paediatrica acta, 1974, Volume: 29, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Body Height; Body Weig

1974
Chronic runt disease in rats: clinical and pathologic studies.
    Journal of the National Cancer Institute, 1969, Volume: 43, Issue:2

    Topics: Animals; Body Weight; Bone Marrow; Graft vs Host Disease; Injections, Intraperitoneal; Lymph Nodes;

1969
Influence of metyrapone on plasma concentrations of testosterone and androstenedione in man.
    Acta endocrinologica, 1971, Volume: 68, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Administration, Oral; Adolescent; Adult

1971
Sex difference in hypertensive action of metopirone in relation to its plasma levels in the rat.
    Endocrinology, 1972, Volume: 90, Issue:4

    Topics: Administration, Oral; Adrenal Glands; Animals; Blood Pressure; Body Weight; Chromatography, Thin Lay

1972
Syndrome of growth resistance, obesity, and intellectual impairment with precocious puberty.
    Archives of disease in childhood, 1972, Volume: 47, Issue:251

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Abnormalities, Multiple; Body Height; Body Weight; Child

1972
Altered adrenal function as an inducer of latent chronic beryllium disease.
    Toxicology and applied pharmacology, 1972, Volume: 23, Issue:3

    Topics: Adrenal Glands; Alkaline Phosphatase; Animals; Berylliosis; Beryllium; Body Weight; Bone and Bones;

1972
Alternate-day corticosteroid regimen.
    Dermatologica, 1971, Volume: 142, Issue:3

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Glands; Adult; Aged; Body Weight; Child; Child, Presc

1971
Metopirone-induced hypertension in the rat.
    Endocrinology, 1970, Volume: 86, Issue:3

    Topics: Adrenal Glands; Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Female; Hypernatremia; H

1970
Long-term corticosteroid therapy in chronic intractable asthmatic patients.
    Annals of allergy, 1971, Volume: 29, Issue:6

    Topics: 17-Hydroxycorticosteroids; Adult; Aged; Asthma; Blood Coagulation Tests; Blood Glucose; Body Weight;

1971
Effect of prolonged inhibition of 11-beta-hydroxylase on gastric secretion, ulcer provocation, and parietal cell population of the dog.
    Surgery, 1968, Volume: 63, Issue:2

    Topics: Adrenal Glands; Animals; Body Weight; Dogs; Gastric Juice; Gastric Mucosa; Histamine; Metyrapone; Mi

1968
Inhibition of cortisol production: its effect on gastric secretion and ulcer provocation.
    The Journal of surgical research, 1968, Volume: 8, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenal Glands; Animals; Body Weight; Dogs; Gastric Juice; Gastric Mucosa;

1968
Iatrogenic hypopituitarism in craniopharyngioma: unexplained catch-up growth in three children.
    The Journal of pediatrics, 1968, Volume: 72, Issue:6

    Topics: 17-Hydroxycorticosteroids; Body Height; Body Weight; Bone Development; Child; Child, Preschool; Cran

1968
Effect of o,p'-DDD and metyrapone (SU-4885) on development of renal hypertension in rats.
    Toxicology and applied pharmacology, 1968, Volume: 12, Issue:3

    Topics: Animals; Blood Pressure; Body Weight; Chlorides; Dichlorodiphenyldichloroethane; Hypertension, Renal

1968
Adrenocortical indices during fasting in obesity.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Glands; Adult; Body Weight; Corticos

1969