metyrapone has been researched along with Blood Pressure, High in 57 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| "All Wistar rats showed hypertension when they were given heat-stress and administered metyrapone (200 micrograms/kg/day), a cholesterol-11-beta-hydroxylase inhibitor." | 7.67 | [Hypertension in rats caused by metyrapone and heat-stress treatment]. ( Arakawa, K, 1985) |
| "The effect of 5 to 9 days of metyrapone administration (400 mg/m2 every 4 h) on aldosterone, deoxycorticosterone, plasma renin activity, electrolyte balance, and blood pressure was investigated in 2 normotensive siblings (one of whom showed limited ACTH reserve), in 3 patients with hypertension and dexamethasone-suppressible hyperaldosteronism, and in a hypertensive patient with primary hyperaldosteronism due to bilateral adrenal hyperplasia." | 7.66 | Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism. ( Levine, LS; New, MI; Sonino, N, 1981) |
| "Treatment with metyrapone thus appears a good therapy for AIMAH, but its effectiveness has not, to our knowledge, been studied." | 5.31 | Rational, effective metyrapone treatment of ACTH-independent bilateral macronodular adrenocortical hyperplasia (AIMAH). ( Nomura, K; Obara, T; Omori, K; Omori, N; Takano, K, 2001) |
| "To determine whether prenatal dietary protein deprivation results in a reduction in nephron number and hypertension in offspring by exposure to maternal glucocorticoids, we administered metyrapone to rats fed either a 6% or 20% protein diet to inhibit glucocorticoid production and compared the offspring to rats that were the product of mothers fed either a 6% or 20% protein diet during the last half of pregnancy." | 3.77 | Evidence that prenatal programming of hypertension by dietary protein deprivation is mediated by fetal glucocorticoid exposure. ( Baum, M; Gattineni, J; Habib, S; Twombley, K, 2011) |
| " Replacement of corticosterone during pregnancy had no effect upon the blood pressures and GPDH activities of male offspring, but it reversed the effects of metyrapone in female offspring." | 3.69 | Hypertension induced by foetal exposure to a maternal low-protein diet, in the rat, is prevented by pharmacological blockade of maternal glucocorticoid synthesis. ( Langley-Evans, SC, 1997) |
| "All Wistar rats showed hypertension when they were given heat-stress and administered metyrapone (200 micrograms/kg/day), a cholesterol-11-beta-hydroxylase inhibitor." | 3.67 | [Hypertension in rats caused by metyrapone and heat-stress treatment]. ( Arakawa, K, 1985) |
| "The effect of 5 to 9 days of metyrapone administration (400 mg/m2 every 4 h) on aldosterone, deoxycorticosterone, plasma renin activity, electrolyte balance, and blood pressure was investigated in 2 normotensive siblings (one of whom showed limited ACTH reserve), in 3 patients with hypertension and dexamethasone-suppressible hyperaldosteronism, and in a hypertensive patient with primary hyperaldosteronism due to bilateral adrenal hyperplasia." | 3.66 | Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism. ( Levine, LS; New, MI; Sonino, N, 1981) |
| "Chronic hypertension has been produced in mongrel dogs by the long-term oral administration of metyrapone (100 mg/kg per day)." | 3.65 | Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs. ( Bravo, EL; Dustan, HP; Tarazi, RC, 1977) |
| "The blood pressure elevation of primary aldosteronism is caused by excessive production of the known mineralocorticoid, aldosterone." | 2.64 | Are there unknown mineralocorticoids in low-renin essential hypertension? ( Hollifield, JW; Island, DP; Liddle, GW; Sennett, JA; Slaton, PE; Wilson, HM; Yarbro, L, 1977) |
| "Ruling out other causes, paraneoplastic hypercortisolism was diagnosed." | 1.51 | Hypokalaemic metabolic alkalosis, hypertension and diabetes: what is the link. ( Cathomas, R; Fehr, T; Kamber, N; Vögelin, M, 2019) |
| "BLA = bilateral adrenalectomy CD = Cushing disease CS = Cushing syndrome eCRF = electronic case report form MRI = magnetic resonance imaging PCOS = polycystic ovary syndrome." | 1.46 | BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY. ( Ayala, A; Biller, BMK; Bonert, V; Broder, MS; Carmichael, JD; Cherepanov, D; Eagan, M; Geer, EB; Gordon, MB; Hannoush, Z; Katznelson, L; Lalazar, Y; Lee, J; Manuylova, E; Neary, MP; Pulaski-Liebert, KJ; Said, Q; Shafiq, I; Surampudi, V; Swerdloff, RS, 2017) |
| "The baby girl underwent medical treatment of Cushing's syndrome with metyrapone which was followed by a rapid recovery." | 1.42 | Neonatal McCune-Albright syndrome with systemic involvement: a case report. ( Dias, P; Gouveia, R; Lourenço, R; Oliveira, G; Sousa, AB, 2015) |
| "Imaging tests by CT/MRI identified the tumors in 8 of 16 (50%), in 4 of 11 (36%) and 4 of 6 (66." | 1.36 | Clinical features and management of ectopic ACTH syndrome at a single institute in Japan. ( Doi, M; Hirata, Y; Izumiyama, H; Sugiyama, T; Yoshimoto, T, 2010) |
| "Treatment with metyrapone thus appears a good therapy for AIMAH, but its effectiveness has not, to our knowledge, been studied." | 1.31 | Rational, effective metyrapone treatment of ACTH-independent bilateral macronodular adrenocortical hyperplasia (AIMAH). ( Nomura, K; Obara, T; Omori, K; Omori, N; Takano, K, 2001) |
| "The hypothesis that hyperaldosteronism is not the sole cause of hypertension in dexamethasone-suppressible hyperaldosteronsim was tested in an 18-year-old male." | 1.26 | Evidence for an unidentified ACTH-induced steroid hormone causing hypertension. ( Levine, LS; New, MI; Peterson, RE; Saenger, P, 1976) |
| "The hypertension was alleviated by the administeration of dexamethasone in 2 of 3 patients with 17 alpha-hydroxylase deficiency." | 1.26 | Hypertension induced by adrenocortical dysfunction--hypertension in 17 alpha-hydroxylase deficiency and metopirone-induced hypertension. ( Kato, E; Kitajima, W; Kondo, K; Konishi, K; Matsuki, S; Nakamura, R; Ohguro, T; Oka, M; Ozawa, Y; Saito, I; Saruta, T; Yamagami, K, 1978) |
| "Aldosterone levels were subnormal but as yet there has been no evidence of overproduction of other mineralocorticoids by chemical analysis or by bioassay of plasma and urinary extracts." | 1.26 | A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol. ( Bradlow, HL; Gunczler, P; Levine, LS; New, MI; Ramirez, LC; Rauh, W; Rösler, A; Ulick, S; Zanconato, G, 1979) |
| "The Metyrapone-treated animals developed severe hypertension with greatly elevated serum creatin phosphokinase, glucose, BUN and cholesterol levels." | 1.26 | Metyrapone-induced cardiovascular degenerative changes in non-arteriosclerotic and arteriosclerotic rats. ( Greenberg, BP; Wexler, BC, 1978) |
| "Medroxyprogesterone (MPA) is a progestin with no clinically detectable estrogenic and androgenic properties used in the treatment of sexual precocity." | 1.25 | Adverse effects of large doses of medroxyprogesterone (MPA) in idiopathic isosexual precocity. ( French, FS; Richman, RA; Underwood, LE; Van Wyk, JJ, 1971) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 44 (77.19) | 18.7374 |
| 1990's | 2 (3.51) | 18.2507 |
| 2000's | 3 (5.26) | 29.6817 |
| 2010's | 7 (12.28) | 24.3611 |
| 2020's | 1 (1.75) | 2.80 |
| Authors | Studies |
|---|---|
| Nemoto, T | 1 |
| Nakakura, T | 1 |
| Kakinuma, Y | 1 |
| Geer, EB | 1 |
| Shafiq, I | 1 |
| Gordon, MB | 1 |
| Bonert, V | 1 |
| Ayala, A | 1 |
| Swerdloff, RS | 1 |
| Katznelson, L | 1 |
| Lalazar, Y | 1 |
| Manuylova, E | 1 |
| Pulaski-Liebert, KJ | 1 |
| Carmichael, JD | 1 |
| Hannoush, Z | 1 |
| Surampudi, V | 1 |
| Broder, MS | 1 |
| Cherepanov, D | 1 |
| Eagan, M | 1 |
| Lee, J | 1 |
| Said, Q | 1 |
| Neary, MP | 1 |
| Biller, BMK | 1 |
| Vögelin, M | 1 |
| Cathomas, R | 1 |
| Kamber, N | 1 |
| Fehr, T | 1 |
| Delivanis, DA | 1 |
| Athimulam, S | 1 |
| Bancos, I | 1 |
| Ito, K | 1 |
| Hirooka, Y | 1 |
| Sunagawa, K | 1 |
| Lourenço, R | 1 |
| Dias, P | 1 |
| Gouveia, R | 1 |
| Sousa, AB | 1 |
| Oliveira, G | 1 |
| Habib, S | 1 |
| Gattineni, J | 1 |
| Twombley, K | 1 |
| Baum, M | 1 |
| Doi, M | 1 |
| Sugiyama, T | 1 |
| Izumiyama, H | 1 |
| Yoshimoto, T | 1 |
| Hirata, Y | 1 |
| Vozarova, B | 1 |
| Weyer, C | 1 |
| Snitker, S | 1 |
| Gautier, JF | 1 |
| Cizza, G | 1 |
| Chrousos, G | 1 |
| Ravussin, E | 1 |
| Tataranni, PA | 1 |
| TORIGAI, T | 1 |
| FUKUCHI, S | 2 |
| HANADA, M | 1 |
| TAKAHASHI, H | 1 |
| IDEMURA, H | 1 |
| KUMAGAI, T | 1 |
| ARMASCRUZ, R | 1 |
| GOMEZ, R | 1 |
| MARDONES, J | 1 |
| PLAZADELOSREYES, M | 1 |
| HOFFMEISTER, W | 1 |
| WEST, CD | 1 |
| KUMAGAI, LF | 1 |
| SIMONS, EL | 1 |
| DOMINGUEZ, OB | 1 |
| BERLINER, DL | 1 |
| RAPP, JP | 1 |
| CRANE, MG | 1 |
| HARRIS, JJ | 1 |
| HERBER, R | 1 |
| Shibata, H | 1 |
| Haruyama, K | 1 |
| Yamazaki, M | 1 |
| Toki, T | 1 |
| Oberfield, SE | 1 |
| Levine, LS | 4 |
| Carey, RM | 1 |
| Greig, F | 1 |
| Ulick, S | 2 |
| New, MI | 6 |
| Nakamura, J | 1 |
| Yakata, M | 1 |
| Sonino, N | 1 |
| Langley-Evans, SC | 1 |
| Omori, N | 1 |
| Nomura, K | 1 |
| Omori, K | 1 |
| Takano, K | 1 |
| Obara, T | 1 |
| Peterson, RE | 1 |
| Saenger, P | 1 |
| Honda, M | 1 |
| Ueda, Y | 1 |
| Tsuchiya, M | 1 |
| Izumi, Y | 1 |
| Watanabe, H | 1 |
| Shiratsuchi, T | 1 |
| Hatano, M | 1 |
| Saruta, T | 1 |
| Nakamura, R | 1 |
| Saito, I | 1 |
| Kondo, K | 1 |
| Ohguro, T | 1 |
| Yamagami, K | 1 |
| Kitajima, W | 1 |
| Oka, M | 1 |
| Konishi, K | 1 |
| Ozawa, Y | 1 |
| Kato, E | 1 |
| Matsuki, S | 1 |
| Gunczler, P | 1 |
| Zanconato, G | 1 |
| Ramirez, LC | 1 |
| Rauh, W | 1 |
| Rösler, A | 1 |
| Bradlow, HL | 1 |
| Hollifield, JW | 1 |
| Slaton, PE | 1 |
| Wilson, HM | 1 |
| Sennett, JA | 1 |
| Yarbro, L | 1 |
| Island, DP | 1 |
| Liddle, GW | 2 |
| Wexler, BC | 1 |
| Greenberg, BP | 1 |
| Tarazi, RC | 2 |
| Bravo, EL | 1 |
| Dustan, HP | 1 |
| Loewenstein, JE | 1 |
| Kolebinov, N | 1 |
| Grigorova-Racheva, R | 1 |
| Vasileva, B | 1 |
| Kishi, K | 1 |
| Kinouchi, T | 1 |
| Shimizu, N | 1 |
| Yoshida, H | 1 |
| Stoner, E | 1 |
| DiMartino-Nardi, J | 1 |
| Connell, JM | 1 |
| Cordiner, J | 1 |
| Davies, DL | 1 |
| Fraser, R | 1 |
| Frier, BM | 1 |
| McPherson, SG | 1 |
| Arakawa, K | 1 |
| Temple, TE | 1 |
| Nagano, T | 1 |
| Miura, K | 2 |
| Miura, S | 1 |
| Hasui, K | 1 |
| Seaman, MP | 1 |
| Tamura, M | 1 |
| Richman, RA | 1 |
| Underwood, LE | 1 |
| French, FS | 1 |
| Van Wyk, JJ | 1 |
| Schaison, G | 1 |
| Okamoto, K | 1 |
| Koller, F | 1 |
| Thorens, B | 1 |
| Riondel, AM | 1 |
| Scholer, D | 1 |
| Kley, HK | 1 |
| Krüskemper, HL | 1 |
| Kellen, JA | 1 |
| Torikai, T | 1 |
| Marks, AD | 2 |
| Adlin, EV | 2 |
| Channick, BJ | 3 |
| Colby, HD | 2 |
| Skelton, FR | 2 |
| Brownie, AC | 1 |
| Tuft, L | 1 |
| Kreze, A | 1 |
| Brownie, A | 1 |
| Nickerson, PA | 1 |
| Molteni, A | 1 |
| Gallant, S | 1 |
8 reviews available for metyrapone and Blood Pressure, High
| Article | Year |
|---|---|
[DRUGS INHIBITING ALDOSTERONE SECRETION AND ALDOSTERONE ANTAGONISTS].
Topics: Aldosterone; Edema; Heparinoids; Hypertension; Ketones; Metyrapone; Mineralocorticoid Receptor Antag | 1963 |
[Corticosterone-producing adrenal tumor].
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Corticosterone; Diagnosis, Differential; Humans; Hy | 2006 |
Hemodynamic role of extracellular fluid in hypertension.
Topics: Animals; Blood Volume; Cardiac Output; Disease Models, Animal; Extracellular Space; Hemodynamics; Ho | 1976 |
Inhibitors of adrenal steroid biosynthesis.
Topics: Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Aldosterone; Aminoglutethimide | 1970 |
[Adrenal cortex function tests and their interpretation].
Topics: Adolescent; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Aldosterone; Androg | 1969 |
[New endocrine disorders attracting current interest--adrenal system].
Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Ho | 1969 |
Spontaneous hypertension in rats.
Topics: Adrenal Medulla; Animals; Antihypertensive Agents; Aorta; Arteries; Autonomic Agents; Body Weight; C | 1969 |
[Aspect of hormones and hypertension].
Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Catechol | 1969 |
2 trials available for metyrapone and Blood Pressure, High
| Article | Year |
|---|---|
Effect of cortisol on muscle sympathetic nerve activity in Pima Indians and Caucasians.
Topics: Adult; Anti-Inflammatory Agents; Cross-Over Studies; Enzyme Inhibitors; Humans; Hydrocortisone; Hype | 2003 |
Are there unknown mineralocorticoids in low-renin essential hypertension?
Topics: Aminoglutethimide; Blood Pressure; Clinical Trials as Topic; Humans; Hyperaldosteronism; Hypertensio | 1977 |
47 other studies available for metyrapone and Blood Pressure, High
| Article | Year |
|---|---|
Elevated blood pressure in high-fat diet-exposed low birthweight rat offspring is most likely caused by elevated glucocorticoid levels due to abnormal pituitary negative feedback.
Topics: Animals; Birth Weight; Blood Pressure; Corticosterone; Diet, High-Fat; Feedback, Physiological; Fema | 2020 |
BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY.
Topics: 14-alpha Demethylase Inhibitors; ACTH-Secreting Pituitary Adenoma; Adenoma; Adolescent; Adrenalectom | 2017 |
Hypokalaemic metabolic alkalosis, hypertension and diabetes: what is the link.
Topics: Alkalosis; Cushing Syndrome; Diabetes Mellitus; Female; Humans; Hypertension; Hypokalemia; Metyrapon | 2019 |
Modern Management of Mild Autonomous Cortisol Secretion.
Topics: 14-alpha Demethylase Inhibitors; Adrenal Cortex Neoplasms; Adrenal Insufficiency; Adrenalectomy; Adr | 2019 |
Corticosterone-activated mineralocorticoid receptor contributes to salt-induced sympathoexcitation in pressure overload mice.
Topics: 11-beta-Hydroxysteroid Dehydrogenase Type 2; Adrenalectomy; Aldosterone; Animals; Corticosterone; Hy | 2014 |
Neonatal McCune-Albright syndrome with systemic involvement: a case report.
Topics: Cafe-au-Lait Spots; Cushing Syndrome; Diagnosis, Differential; Failure to Thrive; Fatal Outcome; Fem | 2015 |
Evidence that prenatal programming of hypertension by dietary protein deprivation is mediated by fetal glucocorticoid exposure.
Topics: Animals; Blood Pressure; Dexamethasone; Diet, Protein-Restricted; Female; Fetus; Hypertension; Kidne | 2011 |
Clinical features and management of ectopic ACTH syndrome at a single institute in Japan.
Topics: ACTH Syndrome, Ectopic; Adrenocorticotropic Hormone; Adult; Aged; Corticotropin-Releasing Hormone; D | 2010 |
[NATRIURETIC DRUGS].
Topics: Acetazolamide; Aldosterone; Ascites; Chlorothiazide; Dexamethasone; Diabetes Insipidus; Diuresis; Di | 1963 |
[PATHOPHYSIOLOGY AND CLINICAL ASPECTS OF SECONDARY ALDOSTERONISM AND ITS TREATMENT].
Topics: Adrenocorticotropic Hormone; Aldosterone; Ascites; Body Fluids; Classification; Dexamethasone; Extra | 1964 |
ADRENOCORTICAL CARCINOMA WITH FEMINIZATION AND HYPERTENSION ASSOCIATED WITH A DEFECT IN 11-BETA-HYDROXYLATION.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acne Vulgaris; Adrenal Cortex Hormones; Adrenal Gland Ne | 1964 |
EFFECT OF AN ALDOSTERONE ANTAGONIST ON ELECTROLYTES AND JUXTAGLOMERULAR GRANULARITY IN ADRENAL REGENERATION HYPERTENSION.
Topics: Adrenal Glands; Angiotensins; Blood; Blood Pressure; Electrolytes; Hypertension; Juxtaglomerular App | 1964 |
PRIMARY ALDOSTERONISM DUE TO AN ADRENAL CARCINOMA.
Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Alkalosis; Blood; Drug Therapy; Hyperaldosteronism | 1965 |
Two cases of low-renin hypertension thought to be due to excessive secretion of unknown mineralocorticoid.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenocorticotropic Hormone; Adult; Aldosterone; Blood P | 1982 |
Metabolic and blood pressure responses to hydrocortisone in the syndrome of apparent mineralocorticoid excess.
Topics: Adrenocorticotropic Hormone; Aldosterone; Blood Pressure; Child; Female; Humans; Hydrocortisone; Hyd | 1983 |
Clinical evaluation of the liquid-chromatographic determination of urinary free cortisol.
Topics: Adolescent; Adrenal Gland Diseases; Adult; Age Factors; Chromatography, High Pressure Liquid; Dexame | 1983 |
Mineralocorticoid and metabolic response to metyrapone on normotensive children and children with dexamethasone-suppressible and primary hyperaldosteronism.
Topics: Aldosterone; Child; Desoxycorticosterone; Electrolytes; Female; Humans; Hyperaldosteronism; Hyperten | 1981 |
Hypertension induced by foetal exposure to a maternal low-protein diet, in the rat, is prevented by pharmacological blockade of maternal glucocorticoid synthesis.
Topics: Animals; Blood Pressure; Corticosterone; Diet, Protein-Restricted; Female; Glucocorticoids; Glycerol | 1997 |
Rational, effective metyrapone treatment of ACTH-independent bilateral macronodular adrenocortical hyperplasia (AIMAH).
Topics: Adrenal Glands; Cushing Syndrome; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Humans; Hydrocortiso | 2001 |
Evidence for an unidentified ACTH-induced steroid hormone causing hypertension.
Topics: 18-Hydroxydesoxycorticosterone; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Adult; Aldoste | 1976 |
Pathogenesis of essential hypertension with low renin: responses of plasma renin activity to various stimulation tests in essential hypertension.
Topics: Adrenocorticotropic Hormone; Adult; Angiotensin II; Circadian Rhythm; Dexamethasone; Humans; Hyperte | 1978 |
Hypertension induced by adrenocortical dysfunction--hypertension in 17 alpha-hydroxylase deficiency and metopirone-induced hypertension.
Topics: Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormone; Adult; Animals; Cushing Syndrome; Deso | 1978 |
A syndrome of apparent mineralocorticoid excess associated with defects in the peripheral metabolism of cortisol.
Topics: 17-Hydroxycorticosteroids; Adrenocorticotropic Hormone; Aldosterone; Child; Cortisone; Humans; Hydro | 1979 |
Metyrapone-induced cardiovascular degenerative changes in non-arteriosclerotic and arteriosclerotic rats.
Topics: Adrenal Glands; Animals; Arteries; Arteriosclerosis; Blood Urea Nitrogen; Body Weight; Cardiovascula | 1978 |
Multifactorial analysis of chronic hypertension induced by electrolyte-active steroids in trained, unanesthetized dogs.
Topics: Acebutolol; Aldosterone; Animals; Chronic Disease; Clonidine; Corticosterone; Diet, Sodium-Restricte | 1977 |
Testing adrenal function--1975.
Topics: Adolescent; Adrenal Cortex Function Tests; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal | 1975 |
[Changes in the corticosteroids and their alpha-ketol metabolites in the urine of hypertension patients treated with metopirons].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aldosterone; Circadian Rhythm; Cortodoxone; Desoxycortic | 1975 |
[Animal models of various hypertensions].
Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenocorticotropic Hormone; Androgens; Angiotensin II; Animals; C | 1992 |
[Clinical significance of serum 11-deoxycorticosterone analysis in endocrine tests of the adrenal cortex].
Topics: Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Desoxycorticosterone; Dexamethasone; Hum | 1989 |
Apparent mineralocorticoid excess causing hypertension and hypokalemia in children.
Topics: 11-beta-Hydroxysteroid Dehydrogenases; Aldosterone; Child; Child, Preschool; Female; Humans; Hydroco | 1986 |
Pregnancy complicated by Cushing's syndrome: potential hazard of metyrapone therapy. Case report.
Topics: Adult; Cushing Syndrome; Female; Humans; Hypertension; Metyrapone; Pregnancy; Pregnancy Complication | 1985 |
[Hypertension in rats caused by metyrapone and heat-stress treatment].
Topics: Animals; Brain; Disease Models, Animal; Dopamine; Hot Temperature; Hypertension; Male; Metyrapone; P | 1985 |
[Urinary excretion of pregnanetriol in various internal diseases].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adolescent; Adrenal Hyperplasia, Congenital; Adrenalecto | 1966 |
[Diurnal variation of plasma cortisol concentration in patients with various diseases and negative feedback mechanism of the pituitary-adrenal axis].
Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenocorticotropic Hormone; Adult; Aged; Central Nervous Sys | 1969 |
Secretion rates of cortisol and aldosterone precursors in various forms of congenital adrenal hyperplasia.
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hor | 1970 |
[Adrenal function in urological patients].
Topics: 17-Hydroxycorticosteroids; Adrenal Cortex Hormones; Adrenal Glands; Adrenocorticotropic Hormone; Adu | 1971 |
Adverse effects of large doses of medroxyprogesterone (MPA) in idiopathic isosexual precocity.
Topics: Adrenal Glands; Adrenal Insufficiency; Adrenocorticotropic Hormone; Body Height; Body Weight; Bone D | 1971 |
[Late-appearing congenital adrenal hyperplasia. Apropos of 3 cases of 11 beta hydroxylase deficiency].
Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Androgens; Dexamethasone; Female; Hirsut | 1974 |
[Proceedings: Cushing's syndrome in hypernephroid carcinoma; normalization of the cortisol value, hypokalemia and hypertension under metopirone].
Topics: Adenocarcinoma; Cushing Syndrome; Humans; Hydrocortisone; Hypertension; Hypokalemia; Kidney Neoplasm | 1974 |
[Performance and interpretation of a shortened metyrapone test].
Topics: 11-Hydroxycorticosteroids; Acromegaly; Adolescent; Adult; Aged; Circadian Rhythm; Diabetes Mellitus; | 1972 |
Failure of metopirone to protect rats from adrenal hypertension induced by 7,12-dimethylbenz (alpha) anthracene.
Topics: Adrenal Glands; Animals; Benz(a)Anthracenes; Female; Hyperplasia; Hypertension; Hypertrophy; Mammary | 1973 |
Effect of metyrapone on plasma renin activity in dogs.
Topics: Animals; Blood Pressure; Desoxycorticosterone; Dexamethasone; Diet, Sodium-Restricted; Disease Model | 1971 |
Metopirone-induced hypertension in the rat.
Topics: Adrenal Glands; Animals; Blood Pressure; Body Weight; Desoxycorticosterone; Female; Hypernatremia; H | 1970 |
Long-term corticosteroid therapy in chronic intractable asthmatic patients.
Topics: 17-Hydroxycorticosteroids; Adult; Aged; Asthma; Blood Coagulation Tests; Blood Glucose; Body Weight; | 1971 |
[Mutual relationship between obesity and hypertension. 3. Adrenocortical activity].
Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Chromatography; Humans; Hypertension; Male; Methods; Met | 1968 |
Adrenal cortical dysfunction as a basis for experimental hypertensive disease.
Topics: Adrenal Glands; Adrenocortical Hyperfunction; Anabolic Agents; Androgens; Animals; Blood Pressure; F | 1969 |
Effects of prolonged inhibition of 11 beta-hydroxylase in the dog.
Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Glands; Animals; Blood; Blood Pressure; Chromatogr | 1966 |