Page last updated: 2024-10-31

metyrapone and Aggression

metyrapone has been researched along with Aggression in 8 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Aggression: Behavior which may be manifested by destructive and attacking action which is verbal or physical, by covert attitudes of hostility or by obstructionism.

Research Excerpts

ExcerptRelevanceReference
"The aims of this study were to (1) describe behavioral and corticosterone elevations that occur in aggressive mice conditioned to respond for the opportunity to fight another mouse, (2) determine if corticosterone elevations are necessary for operant responding and escalated aggression, and (3) determine if corticosterone elevations alter the aggression-heightening effects of gamma-aminobutyric acid (GABA)(A) receptor positive modulators."7.73Escalated aggression as a reward: corticosterone and GABA(A) receptor positive modulators in mice. ( DeBold, JF; Fish, EW; Miczek, KA, 2005)
"The aims of this study were to (1) describe behavioral and corticosterone elevations that occur in aggressive mice conditioned to respond for the opportunity to fight another mouse, (2) determine if corticosterone elevations are necessary for operant responding and escalated aggression, and (3) determine if corticosterone elevations alter the aggression-heightening effects of gamma-aminobutyric acid (GABA)(A) receptor positive modulators."3.73Escalated aggression as a reward: corticosterone and GABA(A) receptor positive modulators in mice. ( DeBold, JF; Fish, EW; Miczek, KA, 2005)
"Metyrapone treatment greatly reduced all agonistic behaviors, groups of fish forming shoals typical of juveniles."1.27Steroid hormones and agonistic behavior in a cichlid teleost, Aequidens pulcher. ( Munro, AD; Pitcher, TJ, 1985)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19903 (37.50)18.7374
1990's0 (0.00)18.2507
2000's3 (37.50)29.6817
2010's2 (25.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aliczki, M1
Varga, ZK1
Balogh, Z1
Haller, J2
Cooper, MA1
Huhman, KL1
Yang, EJ1
Wilczynski, W1
Mikics, E1
Kruk, MR1
Fish, EW1
DeBold, JF1
Miczek, KA1
Liptrap, RM1
Raeside, JI1
Hull, EM1
l'Hommedieu, G1
Kastaniotis, C1
Franz, JR1
Munro, AD1
Pitcher, TJ1

Other Studies

8 other studies available for metyrapone and Aggression

ArticleYear
Involvement of 2-arachidonoylglycerol signaling in social challenge responding of male CD1 mice.
    Psychopharmacology, 2015, Volume: 232, Issue:12

    Topics: Aggression; Agonistic Behavior; Animals; Arachidonic Acids; Benzodioxoles; Cannabinoid Receptor Agon

2015
Blocking corticotropin-releasing factor-2 receptors, but not corticotropin-releasing factor-1 receptors or glucocorticoid feedback, disrupts the development of conditioned defeat.
    Physiology & behavior, 2010, Nov-02, Volume: 101, Issue:4

    Topics: Aggression; Analysis of Variance; Animals; Antimetabolites; Association Learning; Conditioning, Clas

2010
Interaction effects of corticosterone and experience on aggressive behavior in the green anole lizard.
    Hormones and behavior, 2003, Volume: 44, Issue:3

    Topics: Aggression; Agonistic Behavior; Animals; Color; Corticosterone; Enzyme Inhibitors; Enzyme-Linked Imm

2003
Genomic and non-genomic effects of glucocorticoids on aggressive behavior in male rats.
    Psychoneuroendocrinology, 2004, Volume: 29, Issue:5

    Topics: Aggression; Animals; Behavior, Animal; Corticosterone; Cycloheximide; Genomics; Glucocorticoids; Inj

2004
Escalated aggression as a reward: corticosterone and GABA(A) receptor positive modulators in mice.
    Psychopharmacology, 2005, Volume: 182, Issue:1

    Topics: Aggression; Agonistic Behavior; Animals; Arousal; Conditioning, Operant; Corticosterone; Dose-Respon

2005
A relationship between plasma concentrations of testosterone and corticosteroids during sexual and aggressive behaviour in the boar.
    The Journal of endocrinology, 1978, Volume: 76, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Aggression; Animals; Female; Humans; Hydroxyst

1978
Pituitary/adrenal hormones do not influence bulbectomy-induced behavioural changes.
    Physiology & behavior, 1979, Volume: 22, Issue:3

    Topics: Adrenal Cortex; Adrenocorticotropic Hormone; Aggression; Animals; Dexamethasone; Gerbillinae; Humans

1979
Steroid hormones and agonistic behavior in a cichlid teleost, Aequidens pulcher.
    Hormones and behavior, 1985, Volume: 19, Issue:4

    Topics: Aggression; Agonistic Behavior; Animals; Estradiol; Female; Fishes; Hydrocortisone; Metyrapone; Soci

1985