Page last updated: 2024-10-31

metyrapone and Adrenal Gland Diseases

metyrapone has been researched along with Adrenal Gland Diseases in 71 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Adrenal Gland Diseases: Pathological processes of the ADRENAL GLANDS.

Research Excerpts

ExcerptRelevanceReference
" In congenital adrenal hyperplasia, plasma ACTH concentrations mirror, together with 17-alpha-hydroxyprogesterone, the extent of ACTH suppression."3.67Plasma ACTH in diagnosis and control of adrenal disorders. ( Baumann, JB; Eberle, AN; Girard, J, 1986)
"Subnormal plasma 11-deoxycortisol (compound S) responses to metyrapone were found in patients with adrenal insufficiency or with Cushing syndrome caused by adrenal tumors and in those receiving long-term glucocorticoid or diphenylhydantoin sodium therapy."3.65Single-dose metyrapone test: review of a four-year experience. ( Jubiz, W; Meikle, AW; Spiger, M; Tylor, FH; West, CD, 1975)
"Medical therapy to control hypercortisolism in adrenal Cushing's syndrome is currently not the first-line therapy."2.66What is the role of medical therapy in adrenal-dependent Cushing's syndrome? ( Braun, LT; Reincke, M, 2020)
"Six nonadrenalectomized patients with pituitary tumors showed similar abnormalities of ACTH regulation."1.25Studies of ACTH secretion control in 116 cases of Cushing's syndrome. ( Binoux, M; Girard, F; Gourmelen, M; Luton, JP; Raux, MC, 1975)

Research

Studies (71)

TimeframeStudies, this research(%)All Research%
pre-199065 (91.55)18.7374
1990's3 (4.23)18.2507
2000's1 (1.41)29.6817
2010's1 (1.41)24.3611
2020's1 (1.41)2.80

Authors

AuthorsStudies
Braun, LT1
Reincke, M1
Zöllner, EW1
Lombard, C1
Galal, U1
Hough, S1
Irusen, E1
Weinberg, E1
CURRIE, AR2
HELFENSTEIN, JE1
YOUNG, S1
DAO, TL1
TANAKA, Y1
KOSEKI, A1
SHINOHARA, M1
MURAYAMA, K1
TAKANO, J1
TSUNOKAKE, H1
MITSUBE, K1
WONG, TW1
WARNER, NE1
FAGLIA, G1
D ALONZO, R1
NORBIATO, G1
ORTHMANN, G1
LIUZZI, A1
MURPHY, BE1
HOOD, AB1
PATTEE, CJ1
SOLA, OH1
VILANOVA, D1
HOFFMAN, C1
KOSANIK, M1
WAINER, AC1
COPE, CL1
Mizuki, K1
Yanase, T1
Nawata, H1
Nakamura, J1
Yakata, M1
Damani, LA2
Mitterhauser, M2
Lin, G2
Ho, YP2
Zolle, I2
Oehler, E1
Besser, GM1
Jeffcoate, WJ1
Beierwaltes, WH1
Wieland, DM1
Ice, RD1
Seabold, JE1
Sarkar, SD1
Gill, SP1
Mosley, ST1
Raux, MC1
Binoux, M3
Luton, JP3
Gourmelen, M1
Girard, F3
Charro Salgado, AL1
López Macia, A1
Bagazgoitia, J1
Oriol Bosch, A1
Fernández-Cruz, A1
Hashimoto, K2
Takahara, J2
Yunoki, M1
Hosoki, H1
Ofuji, M1
Tragl, KH1
Kinast, H1
Hinterberger, H1
Angelberger, P1
Kletter, K1
Dammacco, F1
Rigillo, N1
Pentasuglia, N1
Zimbalatti, F1
Spiger, M1
Jubiz, W1
Meikle, AW1
West, CD1
Tylor, FH1
Loewenstein, JE1
Zieger, B1
Hubl, W1
Büchner, M1
Aupetit-Faisant, B1
Suda, T1
Tomori, N1
Yajima, F1
Sumitomo, T1
Nakagami, Y1
Ushiyama, T1
Demura, H1
Shizume, K1
Girard, J1
Eberle, AN1
Baumann, JB1
de Peretti, E1
Forest, MG1
Loras, B1
Morel, Y1
David, M1
François, R1
Bertrand, J1
Giusti, G1
Toccafondi, R1
Tarquini, B1
Siegel, ET1
Scarpa, JB1
Etchegoyen, FP1
Rejtman, A1
Materazzi, F1
Ruedi, B1
Felber, JP1
Aubert, M1
Berson, SA2
Yalow, RS2
Minozzi, M1
Faggiano, M1
Salerno, M1
Lombardi, G1
Nunziata, V1
Sako, T1
Sparks, LL1
Smilo, RP1
Pavlatos, FC1
Forsham, PH1
Abe, K1
Nicholson, WE1
Liddle, GW1
Orth, DN1
Island, DP1
Mozziconacci, P1
Miura, K1
Miura, S1
Martin, MM1
Martin, AL1
Ofuji, T1
Bricaire, H1
Norman, N1
Hall, R2
Smith, PA1
Harkness, RA1
Smart, GA1
Gourmelen-Combourieu, M1
Pham-Huu-Trung, MT1
Matsukura, S1
Matsuyama, H1
Nakai, Y1
Imura, H1
Silvestrini, F1
D'Alonzo, R1
Donald, RA2
Espiner, EA2
Beaven, DW2
Kreze, A1
Christy, NP1
Schaison, G1
Hunter, PR1
Ross, W1
Cook, DB1
Steinbeck, AW1
Theile, HM1
Carballeira, A1
Cheng, SC1
Fishman, LM1
Sizonenko, PC1
Doret, AM1
Riondel, AM1
Paunier, L1
Sendrail, M1
Gleizes, L1
Sendrail-Pesqué, M1
Chkili, T1
Fabre, MT1
Vassal, D1
Koepp, P1
Völlmin, JA1
Zachmann, M1
Curtius, HC1
Jellinck, PH2
Garrett, T1
Kupperman, HS1
Tietze, HU1
Zurbrugg, R1
Zuppinger, K1
Joss, E1
Käser, H1
Kato, T1
Kashima, M1
Tsai, ZH1
Shimizu, N1
Araki, Y1
Hofmann, LM1
Sagartz, JW1
Albeaux-Fernet, M1
Bellot, L1
Canet, L1
Deribreux, J1
Gelinet, M1
Frenkel, G1
Kraicer, PF1
Garland, M1
McRitchie, D1
Wheatley, DN2
Jull, JW1
Hamilton, AG1
Boyland, E1
Sims, P1

Reviews

4 reviews available for metyrapone and Adrenal Gland Diseases

ArticleYear
What is the role of medical therapy in adrenal-dependent Cushing's syndrome?
    Best practice & research. Clinical endocrinology & metabolism, 2020, Volume: 34, Issue:3

    Topics: Adrenal Gland Diseases; Cushing Syndrome; Humans; Ketoconazole; Metyrapone; Mitotane; Pituitary ACTH

2020
[Urinary tetrahydro-11-deoxycortisol (THS)].
    Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 8

    Topics: Addison Disease; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Biomarkers; Chromatography, Pa

2005
Plasma levels of aldosterone precursors (including the 18-hydroxylated compounds in this synthesis pathway)--a tool for the analysis of adrenal disorders?
    Hormone research, 1990, Volume: 34, Issue:3-4

    Topics: 18-Hydroxycorticosterone; 18-Hydroxydesoxycorticosterone; Adrenal Gland Diseases; Adrenal Glands; Ad

1990
[New endocrine disorders attracting current interest--adrenal system].
    Horumon to rinsho. Clinical endocrinology, 1969, Volume: 17, Issue:5

    Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Ho

1969

Trials

1 trial available for metyrapone and Adrenal Gland Diseases

ArticleYear
Experience with a rapid oral metyrapone test and the plasma ACTH content in determining the cause of Cushing's syndrome.
    Metabolism: clinical and experimental, 1969, Volume: 18, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gla

1969

Other Studies

66 other studies available for metyrapone and Adrenal Gland Diseases

ArticleYear
Hypothalamic-pituitary-adrenal axis suppression in asthmatic children on inhaled and nasal corticosteroids: is the early-morning serum adrenocorticotropic hormone (ACTH) a useful screening test?
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2011, Volume: 22, Issue:6

    Topics: Administration, Inhalation; Administration, Intranasal; Adolescent; Adrenal Cortex Hormones; Adrenal

2011
Massive adrenal necrosis in rats caused by 9,10-dimethyl-1,2-benzanthracene and its inhibition by metyrapone.
    Lancet (London, England), 1962, Dec-08, Volume: 2, Issue:7267

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Adrenal Gland Diseases; Animals; Benz(a)Anthracenes; Ketones; Mety

1962
INHIBITORY EFFECT OF POLYNUCLEAR HYDROCARBONS AND AMPHENONE ANALOGS ON INDUCTION OF ACUTE ADRENAL NECROSIS BY 7,12-DIMETHYLBENZ(ALPHA)ANTHRACENE.
    Cancer research, 1963, Volume: 23

    Topics: Adrenal Gland Diseases; Anthracenes; Benz(a)Anthracenes; Carcinogens; Hydrocarbons; Ketones; Metyrap

1963
[ENDOCRINOLOGICAL OBSERVATIONS ON CUSHING'S SYNDROME].
    Nihon Sanka Fujinka Gakkai zasshi, 1963, Volume: 15

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocorticotropic Ho

1963
INHIBITION OF DIMETHYLBENZANTHRACENE-INDUCED ADRENAL CORTICAL NECROSIS.
    Endocrinology, 1964, Volume: 74

    Topics: Adrenal Gland Diseases; Benz(a)Anthracenes; Carcinogens; Ketones; Metyrapone; Mineralocorticoid Rece

1964
[SIGNIFICANCE OF THE EVALUATION OF URINARY PREGNANTRIOL IN SOME ADRENAL ENDOCRINE DISORDERS: FINDINGS IN BASAL CONDITIONS AND AFTER TREATMENTS STIMULATING OR INHIBITING THE ADRENAL CORTEX].
    Archivio di patologia e clinica medica, 1964, Volume: 40

    Topics: Adolescent; Adrenal Cortex; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocortical Hyperfun

1964
CLINICAL STUDIES UTILIZING A NEW METHOD FOR THE SERIAL DETERMINATION OF PLASMA CORTICOIDS.
    Canadian Medical Association journal, 1964, Mar-28, Volume: 90

    Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Blood Chemical Analysi

1964
[ADRENAL CORTEX HYPERPLASIA ASSOCIATED WITH HYPERTROPHY OF THE THYMUS GLAND AND ACANTHOSIS NIGICANS IN A CHILD].
    Revista argentina de endocrinologia y metabolismo, 1964, Volume: 10

    Topics: Acanthosis Nigricans; Adrenal Cortex; Adrenal Gland Diseases; Adrenocortical Hyperfunction; Adrenoco

1964
SOME ADRENAL FACTS AND FANCIES.
    Proceedings of the Royal Society of Medicine, 1965, Volume: 58

    Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Blood

1965
Clinical evaluation of the liquid-chromatographic determination of urinary free cortisol.
    Clinical chemistry, 1983, Volume: 29, Issue:5

    Topics: Adolescent; Adrenal Gland Diseases; Adult; Age Factors; Chromatography, High Pressure Liquid; Dexame

1983
Urinary metabolic profile in rat of 1-(2-methoxyphenyl)-2-methyl-2-(3-pyridyl)-1-propanone: a potential radioligand for functional diagnosis of adrenal pathology.
    Xenobiotica; the fate of foreign compounds in biological systems, 1996, Volume: 26, Issue:2

    Topics: Adrenal Gland Diseases; Animals; Biotransformation; Chromatography, High Pressure Liquid; Chromatogr

1996
Metabolic and pharmacokinetic considerations in the design of 2-phenyl substituted metyrapone derivatives: 2-methoxyphenylmetyrapone as a radioligand for functional diagnosis of adrenal pathology.
    Nuclear medicine and biology, 1995, Volume: 22, Issue:8

    Topics: Adrenal Gland Diseases; Adrenal Glands; Animals; Biotransformation; Chromatography, High Pressure Li

1995
Endocrine and metabolic diseases. Adrenal diseases.
    British medical journal, 1976, Feb-21, Volume: 1, Issue:6007

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Insuffici

1976
Localization of radiolabeled enzyme inhibitors in the adrenal gland.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1976, Volume: 17, Issue:11

    Topics: Adrenal Gland Diseases; Adrenal Glands; Aminoglutethimide; Aniline Compounds; Animals; Butanones; Do

1976
Studies of ACTH secretion control in 116 cases of Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 40, Issue:2

    Topics: Adrenal Gland Diseases; Adrenalectomy; Adrenocorticotropic Hormone; Animals; Biological Assay; Cushi

1975
[II. Dexamethasone, metopirone and ACTH tests in the diagnosis of diseases of the hypothalamo-hypopyseal adrenal axis].
    Revista clinica espanola, 1976, May-15, Volume: 141, Issue:3

    Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Dexamethasone; Female;

1976
[Effects of various drugs on human serum ACTH secretion].
    Horumon to rinsho. Clinical endocrinology, 1976, Volume: 24, Issue:3

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Bromocriptine; Dexamethasone; Humans; Hydrocort

1976
Irradiation therapy with 131I-6beta-iodocholesterol of metapyralone induced adrenal hyperplasia in rats.
    Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie, 1978, Mar-20, Volume: 172, Issue:2

    Topics: Adrenal Gland Diseases; Cholesterol; Iodine Radioisotopes; Metyrapone

1978
[Plasma concentrations of metopirone after oral administration in the child].
    Minerva pediatrica, 1976, Jun-16, Volume: 28, Issue:21

    Topics: Administration, Oral; Adrenal Gland Diseases; Child; Humans; Metyrapone; Pituitary Diseases

1976
Single-dose metyrapone test: review of a four-year experience.
    Archives of internal medicine, 1975, Volume: 135, Issue:5

    Topics: Adenoma, Chromophobe; Adolescent; Adrenal Cortex Neoplasms; Adrenal Gland Diseases; Adrenal Glands;

1975
Testing adrenal function--1975.
    The Journal of the Louisiana State Medical Society : official organ of the Louisiana State Medical Society, 1975, Volume: 127, Issue:6

    Topics: Adolescent; Adrenal Cortex Function Tests; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal

1975
[Interpretation of the metopirone--midnight-short-test by means of simultaneous determination and evaluation of the increase of 11-deoxycortisol and decrease of plasma 11-hydroxycorticosteroids].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1975, Aug-15, Volume: 30, Issue:16

    Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Cortodoxone; Humans; H

1975
Immunoreactive corticotropin-releasing factor in human plasma.
    The Journal of clinical investigation, 1985, Volume: 76, Issue:5

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Chromatography, High Pressure Liquid; Co

1985
Plasma ACTH in diagnosis and control of adrenal disorders.
    Acta endocrinologica. Supplementum, 1986, Volume: 279

    Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adre

1986
Usefulness of plasma pregnenolone sulfate in testing pituitary-adrenal function in children.
    Acta endocrinologica. Supplementum, 1986, Volume: 279

    Topics: Adolescent; Adrenal Gland Diseases; Adrenal Insufficiency; Adrenocorticotropic Hormone; Aging; Child

1986
Nycthemeral rhythm of plasma cortisol levels in the Cushing's syndrome associated with hyperplasia of adrenal cortex, before and after treatment of hypophyseal suppression with ultrasonic technique.
    Acta neurovegetativa, 1967, Volume: 30, Issue:1

    Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Circadian Rhy

1967
Assessment of pituitary-adrenal gland function in the dog.
    American journal of veterinary research, 1968, Volume: 29, Issue:1

    Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Animals; Diabetes Mellitus; Do

1968
[Study of the adrenal function with betamethasone].
    Revista clinica espanola, 1966, Aug-31, Volume: 102, Issue:4

    Topics: Adolescent; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Aged; Betamethasone; Child;

1966
[Reichstein's S substance in humans].
    Recenti progressi in medicina, 1966, Volume: 41, Issue:6

    Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; A

1966
[Pituitary syndromes of diencephalic origin. Clinical application of pituitary stimulation tests].
    Schweizerische medizinische Wochenschrift, 1968, Feb-03, Volume: 98, Issue:5

    Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenal Insufficiency; Adrenocorticotropic Hormon

1968
Radioimmunoassay of ACTH in plasma.
    The Journal of clinical investigation, 1968, Volume: 47, Issue:12

    Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Con

1968
[Functional exploration of the adrenal cortex in basal and dynamic conditions in hypercorticism of the Cushing type].
    Folia endocrinologica, 1968, Volume: 21, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocortical Hyperfu

1968
[Clinical studies on the stimulation and suppression of the pituitary-adrenocortical system. II. Studies on the pituitary-adrenocortical suppression test].
    Nihon Naibunpi Gakkai zasshi, 1968, Dec-20, Volume: 44, Issue:9

    Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; C

1968
Normal and abnormal regulation of beta-msh in man.
    The Journal of clinical investigation, 1969, Volume: 48, Issue:8

    Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, C

1969
[Problems raised by fluorometric determination of plasma cortisol in congenital hyperplasia of adrenal glands].
    Pathologie-biologie, 1969, Volume: 17, Issue:9

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Child; Child, Preschool; Chromatography; Chroma

1969
Simultaneous determination of cortisol and corticosterone in urine.
    Clinica chimica acta; international journal of clinical chemistry, 1970, Volume: 27, Issue:3

    Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenocorticotropic Hormone; Child; Circadian Rhythm; Cortic

1970
[Gas liquid chromatography analysis of urinary neutral steroid fractions in normal persons and patients with various diseases].
    Nihon Naibunpi Gakkai zasshi, 1970, Jun-20, Volume: 46, Issue:3

    Topics: 17-Ketosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenocorticotropic Hormon

1970
[Poly-micro-adenomatosis in Cushing's syndrome].
    La Presse medicale, 1970, Oct-17, Volume: 78, Issue:43

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Cushing Syndr

1970
[Biochemical diagnosis of adrenal cortex function].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Nov-01, Volume: 90, Issue:21

    Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormon

1970
A study of the parents of patients with congenital adrenal hyperplasia: detection of the heterozygote.
    Proceedings of the Royal Society of Medicine, 1970, Volume: 63, Issue:10

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Female; Genes, Recessive; Heterozygote; Humans;

1970
[Study of plasma ACTH in 100 human lysine-vasopressin tests].
    Acta endocrinologica, 1971, Volume: 68, Issue:1

    Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Glands; Adrenalectomy; Adrenocorticotro

1971
[Radioimmunoassay of ACTH].
    Saishin igaku. Modern medicine, 1971, Volume: 26, Issue:6

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Humans; Immune Sera; Iodine Isotopes; Methods;

1971
Size heterogeneity of immunoreactive human ACTH in plasma and in extracts of pituitary glands and ACTH-producing thymoma.
    Biochemical and biophysical research communications, 1971, Jul-16, Volume: 44, Issue:2

    Topics: Addison Disease; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Antigens; Chromatography, Gel;

1971
[Behavior of adrenocorticotropic internal secretions in Cushing's syndrome].
    Schweizerische medizinische Wochenschrift, 1970, Oct-03, Volume: 100, Issue:40

    Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Circadian Rhythm; Cu

1970
The effect of metyrapone on corticotrophin secretion.
    The Journal of endocrinology, 1972, Volume: 52, Issue:3

    Topics: Addison Disease; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Circadian Rhythm; Humans; Hydr

1972
Measurement of pituitary hormones: clinical applications. 2. Corticotrophin.
    The New Zealand medical journal, 1972, Volume: 75, Issue:481

    Topics: Addison Disease; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Circadian Rhythm; Cushing Synd

1972
[Steroid diagnosis of adrenal cortex disorders. II. Corticotropin, metopirone and dexamethasone function test].
    Bratislavske lekarske listy, 1973, Volume: 59, Issue:2

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Dexamethasone; Humans; Hypothalamo-Hypophyseal

1973
The clinical significance of pituitary-adrenal suppression by exogenous corticosteroids.
    Journal of chronic diseases, 1973, Volume: 26, Issue:5

    Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenocorticotropic Hormone; Humans; Metyrapone; Pi

1973
[Late-appearing congenital adrenal hyperplasia. Apropos of 3 cases of 11 beta hydroxylase deficiency].
    Annales de medecine interne, 1974, Volume: 125, Issue:2

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Androgens; Dexamethasone; Female; Hirsut

1974
Treatment of Cushing's disease with adrenal blocking drugs and megavoltage therapy to the pituitary.
    Proceedings of the Royal Society of Medicine, 1974, Volume: 67, Issue:12 Pt 1

    Topics: Adrenal Gland Diseases; Adrenocorticotropic Hormone; Adult; Aminoglutethimide; Cushing Syndrome; Fem

1974
The adrenal cortex (excluding aldosteronism).
    Clinics in endocrinology and metabolism, 1974, Volume: 3, Issue:3

    Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex; Adrenal Gland Diseases; Adrenal Glands; Adrenocort

1974
Metabolism of (4-14C) cholesterol by human adrenal glands in vitro and its inhibition by metyrapone.
    Acta endocrinologica, 1974, Volume: 76, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands;

1974
Cushing's syndrome due to bilateral adrenal cortical hyperplasia in a 13-year old girl: successful treatment with op'DDD'.
    Helvetica paediatrica acta, 1974, Volume: 29, Issue:3

    Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Body Height; Body Weig

1974
[Attempted experimental chronic block of adrenal cortex hormone synthesis during growth].
    Pathologie-biologie, 1969, Volume: 17, Issue:21

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal

1969
Determination of urinary tetrahydro-11-deoxycortisol and tetrahydro-11-deoxycorticosterone by gas chromatography.
    Acta endocrinologica, 1971, Volume: 66, Issue:4

    Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adult; Child; Chromatography, Gas; Chromatography,

1971
Metabolism of metopirone and 3-(1,2,3,4-tetrahydro-1-oxo-2 naphthyl)-pyridine in relation to DMBA induced adrenal necrosis.
    Experientia, 1969, Aug-15, Volume: 25, Issue:8

    Topics: Adrenal Gland Diseases; Adrenal Glands; Animals; Benz(a)Anthracenes; Carbon Isotopes; Ethionine; Fem

1969
Steroidogenesis in ovarian malignancy.
    Clinical obstetrics and gynecology, 1969, Volume: 12, Issue:4

    Topics: Adrenal Gland Diseases; Chorionic Gonadotropin; Dexamethasone; Diagnosis, Differential; Female; Gona

1969
[Cortisol regulation in childhood hypoglycemia with adrenal medulla dysfunction].
    Schweizerische medizinische Wochenschrift, 1970, Mar-21, Volume: 100, Issue:12

    Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adrenal Medulla;

1970
The method for the determination of total corticosteroid and 11-deoxycorticosteroid in plasma by competitive protein binding analysis and its application to the overnight metyrapone test.
    Endocrinologia japonica, 1970, Volume: 17, Issue:1

    Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adult; Aged; Child; Female; Humans; Mal

1970
Effects of hydrochlorothiazide, spironolactone and metyrapone on electrolyte excretion and zona glomerulosa width in the sodium depleted rat.
    Archives internationales de pharmacodynamie et de therapie, 1970, Volume: 185, Issue:1

    Topics: Adrenal Gland Diseases; Adrenal Glands; Adrenal Medulla; Animals; Diet, Sodium-Restricted; Hydrochlo

1970
[Inhibitors of adreno-cortical hormone synthesis].
    L'Annee endocrinologique, 1970, Volume: 22

    Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Dichlorodiphenyldichloroethane; Hum

1970
The inhibition of adrenocortical function in the lizard Agama stellio.
    General and comparative endocrinology, 1971, Volume: 17, Issue:1

    Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Animals; Blood Glucose; Depression,

1971
Effect of metopirone and 3-(1,2,3,4-tetrahydro-1-oxo-2-naphthyl)-pyridine on the metabolism of corticosteroids and DMBA in relation to adrenal necrosis.
    Experientia, 1968, Feb-15, Volume: 24, Issue:2

    Topics: Adrenal Gland Diseases; Adrenal Glands; Animals; Benz(a)Anthracenes; Carbon Isotopes; Chromatography

1968
Action of drugs affecting the functioning of the adrenal cortex on adrenal necrosis induced by 7,12-dimethylbenz(alpha)anthracene and its 7-hydroxymethyl derivative in rats.
    Endocrinology, 1968, Volume: 82, Issue:6

    Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Glands; Animals; Benz(a)Anthracenes; Cycloh

1968
7,12-dimethylbenz(a)anthracene-induced adrenocortical necrosis and its inhibition by metopirone (SU4885).
    Cancer research, 1968, Volume: 28, Issue:10

    Topics: Adrenal Gland Diseases; Adrenal Glands; Animals; Benz(a)Anthracenes; Metyrapone; Necrosis; Rats; Tim

1968
Adrenal necrosis induced by 7-hydroxymethyl-12-methylbenz(a)anthracene and its prevention.
    Nature, 1966, Sep-17, Volume: 211, Issue:5055

    Topics: Adrenal Gland Diseases; Animals; Benz(a)Anthracenes; Carbon Tetrachloride; Female; Hepatectomy; Mety

1966