metyrapone and Adrenal Cancer studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Research Excerpts

Excerpt	Relevance	Reference
"Fifteen patients with endogenous Cushing's syndrome were treated with metyrapone and/or amino-glutethimide."	9.05	Aminoglutethimide and metyrapone in the management of Cushing's syndrome. ( Adamson, U; Sjöberg, HE; Thorén, M, 1985)
"Hypercortisolism was successfully controlled with metyrapone, which was started at 8 weeks of gestation."	5.33	Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy. ( Blanco, C; Maqueda, E; Rodriguez, A; Rubio, JA, 2006)
"Fifteen patients with endogenous Cushing's syndrome were treated with metyrapone and/or amino-glutethimide."	5.05	Aminoglutethimide and metyrapone in the management of Cushing's syndrome. ( Adamson, U; Sjöberg, HE; Thorén, M, 1985)
" by metyrapone test or by congenital adrenal hyperplasia resulting from 11 beta-hydroxylase deficiency."	3.69	An alternate pathway to androstenedione synthesis by human adrenals: evidence of a balance in 11 beta-hydroxylase and 17,20-lyase activities leading to androstenedione. ( Auzéby, A; Bogdan, A; Touitou, Y, 1995)
"The most common cause of endogenous Cushing's disease in children older than 7 years is ACTH-dependent Cushing's disease (85%)."	2.45	[Cushing's syndrome: special issues]. ( Goñi Iriarte, MJ, 2009)
"Treatment with metyrapone or o,p'-DDD can always induce a clinical remission but not a cure, and neurotransmitter therapy may be effective in a minority of cases."	2.37	Cushing's syndrome. ( Besser, GM; Howlett, TA; Rees, LH, 1985)
"Hypercortisolism was successfully controlled with metyrapone, which was started at 8 weeks of gestation."	1.33	Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy. ( Blanco, C; Maqueda, E; Rodriguez, A; Rubio, JA, 2006)
"Treatment with metyrapone decreased her cortisol production and produced clinical remission of Cushing's syndrome."	1.25	The immunological hazard of Cushing's syndrome. ( Britton, S; Sjoberg, HE; Thorén, M, 1975)

Timeframe	Studies, this research(%)	All Research%
pre-1990	74 (77.89)	18.7374
1990's	7 (7.37)	18.2507
2000's	8 (8.42)	29.6817
2010's	5 (5.26)	24.3611
2020's	1 (1.05)	2.80

Trial			Phase	Enrollment	Study Type	Start Date	Status
Metabolic, Pressor and Neuropsychological Effects of Metyrapone Treatment in Patients With Hypercortisolism[NCT05255900]				20 participants (Anticipated)	Observational	2022-04-28	Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Article	Year
Ectopic Cushing's syndrome due to a pheochromocytoma: a new case in the post-partum and review of literature. Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology, 2009, Volume: 25, Issue:9 Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cushing Syndrome; Female; Humans; Insulin; Metyrapone	2009
[Cushing's syndrome: special issues]. Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2009, Volume: 56, Issue:5 Topics: Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocortical Hyperfunction; Adult; Child; Cush	2009
[Corticosterone-producing adrenal tumor]. Nihon rinsho. Japanese journal of clinical medicine, 2006, May-28, Volume: Suppl 1 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Corticosterone; Diagnosis, Differential; Humans; Hy	2006
[Cushing syndrome in children]. Annales de pediatrie, 1993, Volume: 40, Issue:7 Topics: Adolescent; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hor	1993
Is it possible to diagnose pituitary-dependent Cushing's disease? Annals of clinical biochemistry, 1985, Volume: 22 ( Pt 6) Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hor	1985
Cushing's syndrome. Clinics in endocrinology and metabolism, 1985, Volume: 14, Issue:4 Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Alcoho	1985
[New endocrine disorders attracting current interest--adrenal system]. Horumon to rinsho. Clinical endocrinology, 1969, Volume: 17, Issue:5 Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Ho	1969
Chemotherapeutic management of the hormone-secreting endocrine malignancies. Cancer, 1972, Volume: 30, Issue:6 Topics: Adenoma, Islet Cell; Adrenal Gland Neoplasms; Aminoglutethimide; Aniline Compounds; Antibiotics, Ant	1972
[Aspect of hormones and hypertension]. Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1969, Jul-10, Volume: 58, Issue:7 Topics: Adolescent; Adrenal Gland Neoplasms; Adult; Age Factors; Aged; Aldosterone; Blood Pressure; Catechol	1969

Article	Year
Aminoglutethimide and metyrapone in the management of Cushing's syndrome. Acta endocrinologica, 1985, Volume: 109, Issue:4 Topics: ACTH Syndrome, Ectopic; Adolescent; Adrenal Gland Neoplasms; Adult; Aminoglutethimide; Clinical Tria	1985
Effect of estrogen on the metabolism of metyrapone and release of ACTH. The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:2 Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Chl	1970
Experience with a rapid oral metyrapone test and the plasma ACTH content in determining the cause of Cushing's syndrome. Metabolism: clinical and experimental, 1969, Volume: 18, Issue:3 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gla	1969

Article	Year
Ectopic ACTH-producing neuroendocrine tumor occurring with large recurrent metastatic pheochromocytoma: a case report. BMC endocrine disorders, 2022, Jul-19, Volume: 22, Issue:1 Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Aged, 80 and over; Cat	2022
Resetting the Abnormal Circadian Cortisol Rhythm in Adrenal Incidentaloma Patients With Mild Autonomous Cortisol Secretion. The Journal of clinical endocrinology and metabolism, 2017, 09-01, Volume: 102, Issue:9 Topics: Adrenal Gland Neoplasms; Aged; Area Under Curve; Body Mass Index; Case-Control Studies; Circadian Rh	2017
Metyrapone-responsive ectopic ACTH-secreting pheochromocytoma with a vicious cycle via a glucocorticoid-driven positive-feedback mechanism. Endocrine journal, 2018, Jul-28, Volume: 65, Issue:7 Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Antimetabolites; Feedback, Physiological; Gluc	2018
Case report: Beneficial effect of 11β-hydroxylase inhibitor in the management of an elderly patient with an androgen-producing inoperable adrenal tumor. Geriatrics & gerontology international, 2013, Volume: 13, Issue:2 Topics: Adrenal Gland Neoplasms; Aged, 80 and over; Androgens; Cushing Syndrome; Dexamethasone; Enzyme Inhib	2013
Rapid control of severe neoplastic hypercortisolism with metyrapone and ketoconazole. European journal of endocrinology, 2015, Volume: 172, Issue:4 Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Adult; Aged; Cushing Synd	2015
Type 2 diabetes identified in pregnancy secondary to Cushing's syndrome. Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2011, Volume: 31, Issue:6 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Cushing Syndrome; Diabetes Mellitus, Type 2	2011
Cushing's syndrome during pregnancy: curative adrenalectomy at 31 weeks gestation. European journal of obstetrics, gynecology, and reproductive biology, 2002, Nov-15, Volume: 105, Issue:2 Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Cushing Syndrome; Female; Gestational A	2002
Steroid metabolites from cholesterol-C14 in a patient with adrenal cancer: effects of metopirone. The Journal of clinical endocrinology and metabolism, 1963, Volume: 23 Topics: Adrenal Gland Neoplasms; Cholesterol; Humans; Metyrapone; Mineralocorticoid Receptor Antagonists; St	1963
EFFECT OF METOPIRONE IN A PATIENT WITH ADRENAL CORTICAL CARCINOMA. Acta endocrinologica, 1963, Volume: 44 Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Carcinoma; Cushing	1963
[TESTING OF THE FUNCTION OF THE PITUITARY GLAND AND THE ADRENAL GLANDS WITH METOPIRONE]. Orvosi hetilap, 1963, Nov-03, Volume: 104 Topics: 17-Ketosteroids; Addison Disease; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands;	1963
[SIGNIFICANCE OF THE EVALUATION OF URINARY PREGNANTRIOL IN SOME ADRENAL ENDOCRINE DISORDERS: FINDINGS IN BASAL CONDITIONS AND AFTER TREATMENTS STIMULATING OR INHIBITING THE ADRENAL CORTEX]. Archivio di patologia e clinica medica, 1964, Volume: 40 Topics: Adolescent; Adrenal Cortex; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocortical Hyperfun	1964
[THE METOPIRONE TEST IN THE DIFFERENTIAL DIAGNOSIS OF VARIOUS ENDOCRINE DISORDERS OF CHILDHOOD]. Rivista di clinica pediatrica, 1963, Volume: 72 Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Carbohydrate Metabolism; Child; Cu	1963
PROBABILITIES OF PITUITARY-ADRENAL RESPONSIVENESS AFTER STEROID THERAPY. Annals of internal medicine, 1964, Volume: 61 Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Biomedical Research; Cushing Syndr	1964
ADRENOCORTICAL CARCINOMA WITH FEMINIZATION AND HYPERTENSION ASSOCIATED WITH A DEFECT IN 11-BETA-HYDROXYLATION. The Journal of clinical endocrinology and metabolism, 1964, Volume: 24 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Acne Vulgaris; Adrenal Cortex Hormones; Adrenal Gland Ne	1964
[THE DIFFERENTIAL DIAGNOSIS OF CUSHING'S SYNDROME]. Deutsche medizinische Wochenschrift (1946), 1964, Dec-11, Volume: 89 Topics: Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Cushing Syndrome	1964
[A SURGICALLY TREATED CASE OF CONN'S SYNDROME. CLINICAL, HISTOLOGICAL AND BIOCHEMICAL FINDINGS]. Schweizerische medizinische Wochenschrift, 1964, May-02, Volume: 94 Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Alkalosis; Humans; Hyperal	1964
[STUDIES ON THE DIAGNOSTIC USE OF METOPIRONE (11-BETA-HYDROXYLASE INHIBITOR) IN DISEASES OF THE PITUITARY AND ADRENAL CORTEX]. Nihon Naibunpi Gakkai zasshi, 1964, Dec-20, Volume: 40 Topics: 17-Hydroxycorticosteroids; Adrenal Cortex; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Blo	1964
PRIMARY ALDOSTERONISM DUE TO AN ADRENAL CARCINOMA. Annals of internal medicine, 1965, Volume: 63 Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Alkalosis; Blood; Drug Therapy; Hyperaldosteronism	1965
Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy. Journal of endocrinological investigation, 2006, Volume: 29, Issue:2 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cushing Syndrome; Enzyme Inhibitors; Female;	2006
[Perioperative treatment of a patient with ectopic ACTH-producing pheochromocytoma]. Masui. The Japanese journal of anesthesiology, 2007, Volume: 56, Issue:4 Topics: Adrenal Gland Neoplasms; Adrenergic alpha-Antagonists; Adrenocorticotropic Hormone; Anesthesia, Epid	2007
Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances. International journal of urology : official journal of the Japanese Urological Association, 2008, Volume: 15, Issue:4 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Depressive Disorder; Female; Humans; Metyrapone; Mi	2008
[Description of a case of virilizing adrenal cortex neoplasm. Considerations on the hormone picture in basal and dynamic conditions]. Folia endocrinologica, 1966, Volume: 19, Issue:5 Topics: 17-Ketosteroids; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Aldosterone; Child; Female; Human	1966
Coexistence of pituitary adrenocorticotropin-dependent Cushing's syndrome with a solitary adrenal adenoma. The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:5 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethasone; Fema	1980
Cushing's syndrome in pregnancy--treatment with metyrapone. Clinical endocrinology, 1982, Volume: 16, Issue:3 Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Cushing Syndrome; Female; Humans; Metyrapone; Pregnancy; Pr	1982
[Cushing's syndrome. Medical treatment of adrenal hypercorticism]. Hormone research, 1980, Volume: 13, Issue:4-5 Topics: Adrenal Gland Neoplasms; Aminoglutethimide; Androstanols; Bromocriptine; Cushing Syndrome; Cyprohept	1980
Adrenal carcinoma. Current therapy in endocrinology and metabolism, 1994, Volume: 5 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dia	1994
An alternate pathway to androstenedione synthesis by human adrenals: evidence of a balance in 11 beta-hydroxylase and 17,20-lyase activities leading to androstenedione. The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:5 Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult	1995
An unusual profile of endocrine study in a patient with pre-Cushing's syndrome. International urology and nephrology, 1993, Volume: 25, Issue:6 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Adenoma; Adrenoc	1993
Change in the composition of adrenal nodules after therapy as revealed by opposed-phase MR imaging. AJR. American journal of roentgenology, 1997, Volume: 169, Issue:2 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aged; Female; Humans; Magnetic Resonance Imaging;	1997
Cost-effectiveness and accuracy of the tests used in the differential diagnosis of Cushing's syndrome. Pituitary, 1999, Volume: 1, Issue:2 Topics: ACTH Syndrome, Ectopic; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adrenocorticotropi	1999
Cushing's syndrome due to phaeochromocytoma secreting the precursors of adrenocorticotropin. The Journal of clinical endocrinology and metabolism, 2000, Volume: 85, Issue:12 Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; alpha-MSH; Anti-Inflamma	2000
Endocrine and metabolic diseases. Adrenal diseases. British medical journal, 1976, Feb-21, Volume: 1, Issue:6007 Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Insuffici	1976
[Paradoxical response of adrenal glands to dexamethasone in a case of adrenal carcinoma]. MMW, Munchener medizinische Wochenschrift, 1975, May-30, Volume: 117, Issue:22 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotr	1975
The diagnostic value of hypothalamic-pituitary-adrenocortical function tests in patients with Cushing's syndrome. Acta medica Okayama, 1975, Volume: 29, Issue:2 Topics: 17-Ketosteroids; Adolescent; Adrenal Cortex Function Tests; Adrenal Gland Neoplasms; Adrenocorticotr	1975
[II. Dexamethasone, metopirone and ACTH tests in the diagnosis of diseases of the hypothalamo-hypopyseal adrenal axis]. Revista clinica espanola, 1976, May-15, Volume: 141, Issue:3 Topics: Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Dexamethasone; Female;	1976
[Auxological problems in a case of virilizing adenoma of the adrenal gland]. Minerva pediatrica, 1977, Mar-24, Volume: 29, Issue:10 Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Child; Child, Preschool; Dexamethasone; Growth Di	1977
Specific radioimmunoassay of human beta-endorphin in unextracted plasma. The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:3 Topics: Adenoma; Adrenal Gland Neoplasms; Carcinoma, Bronchogenic; Cushing Syndrome; Dexamethasone; Endorphi	1979
Feminizing adrenocortical carcinoma with Cushing's syndrome and pseudohyperparathyroidism. Archives of internal medicine, 1978, Volume: 138, Issue:2 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult	1978
Imaging the adrenal glands with radiolabeled inhibitors of enzymes: concise communication. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1978, Volume: 19, Issue:2 Topics: Adrenal Gland Neoplasms; Adrenal Glands; Animals; Breast Neoplasms; Dogs; Enzyme Inhibitors; Humans;	1978
The immunological hazard of Cushing's syndrome. British medical journal, 1975, Dec-20, Volume: 4, Issue:5998 Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Cryptococcosis; Cushing Syndrome; Female; Fluorouracil; Hum	1975
Cushing's syndrome with fluctuation due to adrenal adenoma. The Journal of clinical endocrinology and metabolism, 1975, Volume: 41, Issue:2 Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Circadian Rh	1975
Dual sites of inhibition by metyrapone of human adrenal steroidogenesis: correlation of in vivo and in vitro studies. The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:4 Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adrenoco	1976
A case of asymptomatic cortisol producing adrenal adenoma. Endocrinologia japonica, 1992, Volume: 39, Issue:1 Topics: Adenoma; Adrenal Gland Neoplasms; Cushing Syndrome; Dexamethasone; Humans; Hydrocortisone; Hypothala	1992
Adrenal insufficiency after operative removal of apparently nonfunctioning adrenal adenomas. JAMA, 1989, Feb-10, Volume: 261, Issue:6 Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenalectomy; Dex	1989
Cushing's syndrome presenting the coexistence of a pituitary corticotrophic cell hyperplasia and a unilateral functional adrenal adenoma. Acta endocrinologica, 1985, Volume: 110, Issue:3 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Circadian Rhythm; Cush	1985
[Inhibitors of corticosteroid formation. I. The first adrenal cortex inhibitors]. La Presse medicale, 1968, May-04, Volume: 76, Issue:22 Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfunction; Anti	1968
Clinical and biochemical studies of a patient with a corticosterone-secreting adrenocortical tumour. Lancet (London, England), 1968, Nov-23, Volume: 2, Issue:7578 Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Depression, Chemical; Feces; Female; Humans; Metyr	1968
Patterns of urinary excretion of steroids in Cushing's syndrome. The Journal of clinical endocrinology and metabolism, 1966, Volume: 26, Issue:3 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; A	1966
Studies in a patient with an ectopic adrenocortical tumor. The Journal of clinical endocrinology and metabolism, 1966, Volume: 26, Issue:3 Topics: 17-Hydroxycorticosteroids; Adenocarcinoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotrop	1966
Suppression of tumorous adrenal hyperfunction by aminoglutethimide. Metabolism: clinical and experimental, 1967, Volume: 16, Issue:4 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfu	1967
Functional adrenocortical carcinoma in a dog. Journal of the American Veterinary Medical Association, 1967, Apr-01, Volume: 150, Issue:7 Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Adrenocorticotropic Hormone;	1967
[Reichstein's S substance in humans]. Recenti progressi in medicina, 1966, Volume: 41, Issue:6 Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; A	1966
Vasopressin in the evaluation of pituitary-adrenal function. Annals of internal medicine, 1968, Volume: 69, Issue:2 Topics: Acromegaly; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Anorex	1968
Radioimmunoassay of ACTH in plasma. The Journal of clinical investigation, 1968, Volume: 47, Issue:12 Topics: 17-Hydroxycorticosteroids; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Con	1968
A simple method for the separate estimation of 11-deoxy and 11-oxygenated 17-hydroxycortico-steroids in human urine. The Journal of endocrinology, 1968, Volume: 41, Issue:2 Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Gland Neoplasms; Adrenal Hyperplasia, Congenital; Adr	1968
[Functional exploration of the adrenal cortex in basal and dynamic conditions in hypercorticism of the Cushing type]. Folia endocrinologica, 1968, Volume: 21, Issue:3 Topics: 17-Ketosteroids; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocortical Hyperfu	1968
[Present state of the dynamic studies of the adrenal cortex (excepting and aldosterone function)]. La Presse medicale, 1968, Nov-23, Volume: 76, Issue:45 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Addison Disease; Adrenal Gland Neoplasms; Adrenal Insuff	1968
Normal and abnormal regulation of beta-msh in man. The Journal of clinical investigation, 1969, Volume: 48, Issue:8 Topics: Addison Disease; Adolescent; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Hyperplasia, C	1969
Diagnosis of Cushing's syndrome. The differentiation between adrenocortical hyperplasia and adrenocrotical adenoma by means of lysine-vasopressin. Acta endocrinologica, 1969, Volume: 60, Issue:1 Topics: 17-Hydroxycorticosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone	1969
Anomalous response to metyrapone in Cushing's syndrome due to adrenocortical adenoma. The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:1 Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Cus	1970
Evaluation of stimulation and suppression tests in the etiological diagnosis of Cushing's syndrome. Annals of internal medicine, 1969, Volume: 71, Issue:5 Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Ang	1969
Cushing's syndrome caused by a metyrapone responsive adrenocortical adenoma. The Journal of clinical endocrinology and metabolism, 1970, Volume: 31, Issue:2 Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Horm	1970
[Poly-micro-adenomatosis in Cushing's syndrome]. La Presse medicale, 1970, Oct-17, Volume: 78, Issue:43 Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Cushing Syndr	1970
[Biochemical diagnosis of adrenal cortex function]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1970, Nov-01, Volume: 90, Issue:21 Topics: Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormon	1970
[Radioimmunoassay of ACTH]. Nihon Naibunpi Gakkai zasshi, 1971, May-20, Volume: 47, Issue:2 Topics: 17-Hydroxycorticosteroids; Addison Disease; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Ho	1971
Results of treatment in 108 patients with Cushing's syndrome. The New England journal of medicine, 1971, Jul-29, Volume: 285, Issue:5 Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Age	1971
[Cushing's syndrome]. Naika. Internal medicine, 1971, Volume: 27, Issue:6 Topics: Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Cushing Syndrome; Dexametha	1971
Tests of adrenocortical function. The New England journal of medicine, 1971, Nov-18, Volume: 285, Issue:21 Topics: Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocorticotropic Hormone; Cushing Syndrome; Dexam	1971
[Function studies of the hypothalamus-anterior-pituitary-adrenal cortex system following surgery of cortisol-producing adrenal gland adenoma]. Deutsche medizinische Wochenschrift (1946), 1972, Aug-04, Volume: 97, Issue:31 Topics: 17-Hydroxycorticosteroids; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Insufficienc	1972
[Urinary 6beta-hydroxycortisol. II. Urinary 6beta-hydroxycortisol in different diseases and after administration of drugs]. Nihon Naibunpi Gakkai zasshi, 1973, Jun-20, Volume: 49, Issue:6 Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Carcinoma; Cushing Syndrome; F	1973
[Urinary steroids under the effect of standardized dynamic tests]. Studii si cercetari de endocrinologie, 1972, Volume: 23, Issue:2 Topics: Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Chorionic Gonadotropin; Cryptorchidism;	1972
Metabolism of (4-14C) cholesterol by human adrenal glands in vitro and its inhibition by metyrapone. Acta endocrinologica, 1974, Volume: 76, Issue:4 Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands;	1974
Hypocholesterolaemia in hyperadrenal states. British medical journal, 1973, Jul-21, Volume: 3, Issue:5872 Topics: 17-Ketosteroids; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Androstanes; Cholesterol; Fe	1973
An assessment of the metyrapone test. Clinical endocrinology, 1973, Volume: 2, Issue:3 Topics: Adrenal Gland Neoplasms; Adult; Aged; Chromatography, Gas; Cushing Syndrome; Diagnosis, Differential	1973
Adrenal adenoma with variable response to dexamethasone suppression and metyrapone stimulation. The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:5 Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfun	1972
[Drug therapy of adrenal gland hyperfunction]. Deutsche medizinische Wochenschrift (1946), 1972, Mar-24, Volume: 97, Issue:12 Topics: Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenocortical Hyperfunction; Aminoglutethimide; A	1972
Excretion of urinary free amino acids in Cushing's syndrome. The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:12 Topics: 17-Hydroxycorticosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Amino	1969
Use of lysin-vasopressin in the differential diagnosis of cushing's syndrome. Acta endocrinologica, 1970, Volume: 65, Issue:4 Topics: Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cushing Syndrome; Diagnosis, Differential; Female; Hu	1970
[Clinical studies on urinary 17-ketogenic steroid fractions. 3. SU-4885 test in normal subjects and the patients with various endocrine disorders]. Nihon Naibunpi Gakkai zasshi, 1968, Mar-20, Volume: 43, Issue:12 Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland N	1968
A comparison of of the potency of some 11beta-hydroxylase inhibitors using rat and human adrenal tissue. The Journal of endocrinology, 1968, Volume: 41, Issue:4 Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Animals; Carbon Isotopes;	1968
A simplified metyrapone test with determination of plasma ll-deoxycortisol (Metyrapone test with plasma S). The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:7 Topics: 17-Hydroxycorticosteroids; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenocortical Hyperfunct	1969
Cushing's syndrome in infancy. The Journal of pediatrics, 1969, Volume: 75, Issue:3 Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Abnormalities, Multiple; Adenoma; Adrenal Gland Neoplasm	1969
Failure of dexamethasone suppression in adrenal hyperplasia. Archives of internal medicine, 1966, Volume: 118, Issue:3 Topics: Adrenal Gland Neoplasms; Adult; Cushing Syndrome; Dexamethasone; Diagnosis, Differential; Humans; Hy	1966

metyrapone and Adrenal Cancer

Research Excerpts

Research

Studies (95)

Authors

Clinical Trials (1)

Trial Overview

Reviews

Trials

Other Studies

Authors	Studies
Saishouji, F	1
Maeda, S	1
Hamada, H	1
Kimura, N	1
Tamanoi, A	1
Nishida, S	1
Sakaguchi, M	1
Igata, M	1
Yokoo, K	1
Kawakami, F	1
Araki, E	1
Kondo, T	1
Debono, M	1
Harrison, RF	1
Chadarevian, R	1
Gueroult, C	1
Abitbol, JL	1
Newell-Price, J	1
Inoue, M	1
Okamura, K	1
Kitaoka, C	1
Kinoshita, F	1
Namitome, R	1
Nakamura, U	1
Shiota, M	1
Goto, K	1
Ohtsubo, T	1
Matsumura, K	1
Oda, Y	1
Eto, M	1
Kitazono, T	1
Ozawa, W	1
Sato, K	1
Miyakoshi, T	1
Nishio, S	1
Yamazaki, M	1
Suzuki, S	1
Komatsu, M	1
Corcuff, JB	1
Young, J	1
Masquefa-Giraud, P	1
Chanson, P	1
Baudin, E	1
Tabarin, A	1
Cohade, C	1
Broussaud, S	1
Louiset, E	1
Bennet, A	1
Huyghe, E	1
Caron, P	1
Goñi Iriarte, MJ	1
Schiemer, R	1
Latibeaudiere, M	1
Close, C	1
Fox, R	1
Shaw, JA	1
Pearson, DW	1
Krukowski, ZH	1
Fisher, PM	1
Bevan, JS	2
SAROFF, J	1
SLAUNWHITE, WR	1
COSTA, G	1
SANDBERG, AA	1
DANIELS, H	1
SCHOPMAN, W	1
GOTH, E	1
POLLAK, L	1
FAGLIA, G	1
D ALONZO, R	1
NORBIATO, G	1
ORTHMANN, G	1
LIUZZI, A	1
BOSCHERINI, B	1
FISCHETTI, M	1
DANOWSKI, TS	1
BONESSI, JV	1
SABEH, G	1
SUTTON, RD	1
WEBSTER, MW	1
SARVER, ME	1
WEST, CD	3
KUMAGAI, LF	1
SIMONS, EL	1
DOMINGUEZ, OB	1
BERLINER, DL	1
TAMM, J	1
MINDER, E	1
MARKOFF, NG	1
NEHER, R	1
KAHNT, FW	1
KUMAGAI, H	1
CRANE, MG	1
HARRIS, JJ	1
HERBER, R	1
Blanco, C	1
Maqueda, E	1
Rubio, JA	1
Rodriguez, A	1
Shibata, H	1
Shigekawa, T	1
Sato, T	2
Mizobuchi, S	1
Nakatsuka, H	1
Yokoyama, M	1
Morita, K	1
Obinata, D	1
Yamaguchi, K	1
Hirano, D	1
Yoshida, T	1
Soma, M	1
Takahashi, S	1
Faggiano, M	2
Minozzi, M	2
Nunziata, V	2
Lombardi, G	2
Franza, C	1
Schteingart, DE	1
Tsao, HS	1
Gormley, MJ	1
Hadden, DR	1
Kennedy, TL	1
Montgomery, DA	1
Murnaghan, GA	1
Sheridan, B	1
Bricaire, H	4
Luton, JP	4
Freeman, DA	1
Auzéby, A	1
Bogdan, A	1
Touitou, Y	1
Kodama, C	1
Nakada, T	1
Sasagawa, I	1
Ishigooka, M	1
Yamaguchi, T	1
Suzuki, H	1
Raux-Demay, MC	1
Girard, F	1
Kainz, G	1
Mammone, J	1
Outwater, EK	1
Puig, J	1
Wägner, A	1
Caballero, A	1
Rodríguez-Espinosa, J	1
Webb, SM	1
White, A	1
Ray, DW	1
Talbot, A	1
Abraham, P	1
Thody, AJ	1
Besser, GM	2
Jeffcoate, WJ	1
Hashimoto, K	1
Charro Salgado, AL	1
López Macia, A	1
Bagazgoitia, J	1
Oriol Bosch, A	1
Fernández-Cruz, A	1
Tecilazich, D	1
Rosenwirth, D	1
Tonini, G	1
Mangiarotti-Marchi, MA	1
Wiedemann, E	1
Saito, T	1
Linfoot, JA	1
Li, CH	1
deAsis, DN	1
Samaan, NA	1
Beierwaltes, WH	1
Wieland, DM	1
Mosley, ST	1
Swanson, DP	1
Sarkar, SD	1
Freitas, JE	1
Thrall, JH	1
Herwig, KR	1
Britton, S	1
Thorén, M	2
Sjoberg, HE	2
Green, JR	1
van't Hoff, W	1
Carballeira, A	2
Fishman, LM	2
Jacobi, JD	1
Noritake, M	1
Morimoto, K	1
Kosano, H	1
Nemoto, Y	1
Kugai, N	1
Takao, M	1
Murai, M	1
Tamai, S	1
Tanaka, K	1
Nagata, N	1
Huiras, CM	1
Pehling, GB	1
Caplan, RH	1
Watanobe, H	1
Kawagishi, T	1
Hirai, Y	1
Tsutsui, M	1
Kamata, Y	1
Takebe, K	1
Howlett, TA	2
Rees, LH	2
Adamson, U	1
Philbert, M	1
Mathieu de Fossey, B	1
Fraser, R	1
James, VH	1
Landon, J	1
Peart, WS	1
Rawson, A	1
Giles, CA	1
McKay, AM	1
Meikle, AW	2
Jubiz, W	2
Matsukura, S	1
Harada, G	1
Tyler, FH	2
Martin, MM	1
Hamman, BL	1
Ney, RL	1
Hammond, W	1
Wright, L	1
Davis, WW	1
Acker, J	1
Bartter, FC	1
Smilo, RP	2
Earll, JM	1
Forsham, PH	2
Siegel, ET	1
O'Brien, JB	1
Pyle, L	1
Schryver, HF	1
Materazzi, F	1
Tucci, JR	1
Espiner, EA	1
Jagger, PI	2
Lauler, DP	2
Thorn, GW	1
Berson, SA	1
Yalow, RS	1
Few, JD	1
Salerno, M	1
Sparks, LL	1
Pavlatos, FC	1
Leprat, J	1
Abe, K	1
Nicholson, WE	1
Liddle, GW	2
Orth, DN	2
Island, DP	1
Bethge, H	2
Bayer, JM	2
Winkelmann, W	2
Miura, K	1
Miura, S	1
Pennington, LF	1
Kreisberg, RA	1
Hershman, JM	1
Weiss, ER	1
Rayyis, SS	1
Nelson, DH	1
Bethune, JE	1
Crystal, RG	1
Rose, LI	1
Norman, N	1
Yuji, S	1
Nakajima, T	1
Watanabe, A	1
Shimizu, N	1
Kato, T	1
Kracht, J	1
Hackenberg, K	1
Schein, PS	1
Yamada, S	1
Drafta, D	1
Ciocîrdia, C	1
Stroe, E	1
Tache, A	1
Cristoveanu, A	1
Bunea, M	1
Cheng, SC	1
Reschini, E	1
Giustina, G	1
Shahmanesh, M	1
Hartog, M	1
Crook, D	1
Torikai, T	1
Matthews, JI	1
Fariss, BL	1
Chertow, BS	1
Howard, WB	1
Raith, L	1
Jones, JE	1
Graham, NA	1
Seal, US	1
Croughs, RJ	1
Tada, T	1
Sprunt, JG	1
Hannah, DM	1
Hutchings, MP	1
Loridan, L	1
Senior, B	1
Katz, J	1