Page last updated: 2024-10-31

metyrapone and Adenoma, Basal Cell

metyrapone has been researched along with Adenoma, Basal Cell in 86 studies

Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

Research Excerpts

ExcerptRelevanceReference
"18 patients were studied on 21 occasions: three with Cushing's disease without metyrapone treatment prior to IPSS (M-), 11 with Cushing's disease with metyrapone pretreatment (M+), three with ectopic ACTH syndrome, and one with pseudo-Cushing's syndrome."7.69Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome. ( Atkinson, RL; Cameron, DP; Cuneo, RC; Harper, J; Lee, W; Mitchell, K; Salkield, I; Ward, G, 1997)
"To analyse the clinical and biochemical effects of metyrapone in the treatment of Cushing's syndrome."7.68Short and long-term responses to metyrapone in the medical management of 91 patients with Cushing's syndrome. ( Besser, GM; Grossman, AB; Howlett, TA; Perry, L; Rees, LH; Trainer, PJ; Verhelst, JA; Wass, JA, 1991)
"A diagnosis of preclinical Cushing's disease was made, and she was treated with 11-hydroxylase inhibitor metyrapone."5.34Preclinical Cushing's disease characterized by massive adrenal hyperplasia and hormonal changes after three years of metyrapone therapy. ( Nomura, K; Ohmori, K; Ohmori, N; Takano, K, 2007)
"Hypercortisolism was successfully controlled with metyrapone, which was started at 8 weeks of gestation."5.33Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy. ( Blanco, C; Maqueda, E; Rodriguez, A; Rubio, JA, 2006)
"Aldosterone excretion was high, normal, or low in each of the three types of Cushing's syndrome."5.26Deoxycorticosterone and aldosterone excretion in Cushing's syndrome. ( Cassar, J; Joplin, GF; Kelly, WF; Loizou, S; Mashiter, K, 1980)
" by metyrapone test or by congenital adrenal hyperplasia resulting from 11 beta-hydroxylase deficiency."3.69An alternate pathway to androstenedione synthesis by human adrenals: evidence of a balance in 11 beta-hydroxylase and 17,20-lyase activities leading to androstenedione. ( Auzéby, A; Bogdan, A; Touitou, Y, 1995)
"18 patients were studied on 21 occasions: three with Cushing's disease without metyrapone treatment prior to IPSS (M-), 11 with Cushing's disease with metyrapone pretreatment (M+), three with ectopic ACTH syndrome, and one with pseudo-Cushing's syndrome."3.69Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome. ( Atkinson, RL; Cameron, DP; Cuneo, RC; Harper, J; Lee, W; Mitchell, K; Salkield, I; Ward, G, 1997)
"To analyse the clinical and biochemical effects of metyrapone in the treatment of Cushing's syndrome."3.68Short and long-term responses to metyrapone in the medical management of 91 patients with Cushing's syndrome. ( Besser, GM; Grossman, AB; Howlett, TA; Perry, L; Rees, LH; Trainer, PJ; Verhelst, JA; Wass, JA, 1991)
" In congenital adrenal hyperplasia, plasma ACTH concentrations mirror, together with 17-alpha-hydroxyprogesterone, the extent of ACTH suppression."3.67Plasma ACTH in diagnosis and control of adrenal disorders. ( Baumann, JB; Eberle, AN; Girard, J, 1986)
"Hypercortisolism induced by Cushing disease causes high morbidity and mortality."2.48New prospects for drug treatment in Cushing disease. ( Barahona Constanzo, MJ; del Pozo Picó, C, 2012)
"Effective treatment of Cushing's disease can normalize biochemical levels, reverse comorbidities, and improve overall survival and quality of life."2.45Rationale for treatment and therapeutic options in Cushing's disease. ( Petersenn, S; Stewart, PM, 2009)
"Since hypercortisolism due to active Cushing's disease may worsen a COVID-19 infection, multi-disciplinary management that includes appropriate and prompt treatment strategies is mandatory in such cases."1.62Successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia. ( Atsumi, T; Cho, KY; Inoshita, N; Kamada, K; Kameda, H; Kenmotsu, Y; Konno, S; Miyoshi, H; Nakakubo, S; Nakamura, A; Nakamura, J; Nomoto, H; Sawamura, Y; Shimatsu, A; Sugino, H; Suzuki, M; Takahashi, Y; Yamashita, Y; Yuno, A, 2021)
"BLA = bilateral adrenalectomy CD = Cushing disease CS = Cushing syndrome eCRF = electronic case report form MRI = magnetic resonance imaging PCOS = polycystic ovary syndrome."1.46BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY. ( Ayala, A; Biller, BMK; Bonert, V; Broder, MS; Carmichael, JD; Cherepanov, D; Eagan, M; Geer, EB; Gordon, MB; Hannoush, Z; Katznelson, L; Lalazar, Y; Lee, J; Manuylova, E; Neary, MP; Pulaski-Liebert, KJ; Said, Q; Shafiq, I; Surampudi, V; Swerdloff, RS, 2017)
"The hypercortisolism is a rare endocrine disease characterized by an autonomous steroid secretion or excessive adrenal stimulation by ACTH."1.43[Indications and future perspectives in the pharmacological treatment of hypercortisolism]. ( Stigliano, A; Toscano, V, 2016)
"A long-term recurrence rate of Cushing's disease ranging from 2%-25% has been reported."1.39[Predictors of long-term remission after transsphenoidal surgery in Cushing's disease]. ( Abellán Galiana, P; Escrivá, CM; Fajardo Montañana, C; Gómez Vela, J; Lillo, VR; Riesgo Suárez, PA, 2013)
"Because TS may cause pituitary insufficiency in some of these patients, early postoperative assessment of pituitary function is essential for appropriate endocrine management."1.38The use of an early postoperative CRH test to assess adrenal function after transsphenoidal surgery for pituitary adenomas. ( Biermasz, NR; Kokshoorn, NE; Pereira, AM; Rambach, AH; Roelfsema, F; Romijn, JA; Smit, JW, 2012)
"A diagnosis of preclinical Cushing's disease was made, and she was treated with 11-hydroxylase inhibitor metyrapone."1.34Preclinical Cushing's disease characterized by massive adrenal hyperplasia and hormonal changes after three years of metyrapone therapy. ( Nomura, K; Ohmori, K; Ohmori, N; Takano, K, 2007)
"Hypercortisolism was successfully controlled with metyrapone, which was started at 8 weeks of gestation."1.33Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy. ( Blanco, C; Maqueda, E; Rodriguez, A; Rubio, JA, 2006)
"In vitro perifusion of the pituitary adenoma obtained by surgery revealed that o-CRF also stimulated ACTH and beta-EP release in a dose-responsive manner (10(-9)M 10(-5)M) and that dopamine suppressed their basal secretion."1.27Effect of ovine corticotrophin releasing factor, bromocriptine, and dopamine on release of ACTH and beta-endorphin in a patient with Cushing's disease. ( Fujita, T; Hirata, Y; Nakashima, H; Tomita, M; Uchihashi, M, 1985)
"Aldosterone excretion was high, normal, or low in each of the three types of Cushing's syndrome."1.26Deoxycorticosterone and aldosterone excretion in Cushing's syndrome. ( Cassar, J; Joplin, GF; Kelly, WF; Loizou, S; Mashiter, K, 1980)
"Treatment with metyrapone decreased her cortisol production and produced clinical remission of Cushing's syndrome."1.25The immunological hazard of Cushing's syndrome. ( Britton, S; Sjoberg, HE; Thorén, M, 1975)

Research

Studies (86)

TimeframeStudies, this research(%)All Research%
pre-199061 (70.93)18.7374
1990's8 (9.30)18.2507
2000's9 (10.47)29.6817
2010's6 (6.98)24.3611
2020's2 (2.33)2.80

Authors

AuthorsStudies
Newell-Price, J1
Nieman, LK1
Reincke, M1
Tabarin, A1
Yuno, A1
Kenmotsu, Y1
Takahashi, Y1
Nomoto, H1
Kameda, H1
Cho, KY1
Nakamura, A1
Yamashita, Y1
Nakamura, J1
Nakakubo, S1
Kamada, K1
Suzuki, M1
Sugino, H1
Inoshita, N1
Konno, S1
Miyoshi, H1
Atsumi, T1
Sawamura, Y1
Shimatsu, A1
Geer, EB1
Shafiq, I1
Gordon, MB1
Bonert, V1
Ayala, A1
Swerdloff, RS1
Katznelson, L1
Lalazar, Y1
Manuylova, E1
Pulaski-Liebert, KJ1
Carmichael, JD1
Hannoush, Z1
Surampudi, V1
Broder, MS1
Cherepanov, D1
Eagan, M1
Lee, J1
Said, Q1
Neary, MP1
Biller, BMK1
Stigliano, A1
Toscano, V1
Stewart, PM1
Petersenn, S1
Schiemer, R1
Latibeaudiere, M1
Close, C1
Fox, R1
Kokshoorn, NE1
Romijn, JA1
Roelfsema, F1
Rambach, AH1
Smit, JW1
Biermasz, NR1
Pereira, AM1
Barahona Constanzo, MJ1
del Pozo Picó, C1
Abellán Galiana, P1
Fajardo Montañana, C1
Riesgo Suárez, PA1
Gómez Vela, J1
Escrivá, CM1
Lillo, VR1
Shaw, JA1
Pearson, DW1
Krukowski, ZH1
Fisher, PM1
Bevan, JS1
KAPLAN, NM2
JANSEN, W1
DOORENBOS, H1
BEKS, JW1
JENKINS, JS3
ELKINGTON, SG2
SOBOTA, JT1
REED, RJ1
MINDER, E1
MARKOFF, NG1
NEHER, R1
KAHNT, FW1
HOLMDAHL, TH1
DITZEL, J1
Miyoshi, T1
Otsuka, F1
Suzuki, J1
Inagaki, K1
Takeda, M1
Kano, Y1
Yamashita, T1
Ogura, T1
Date, I1
Tanaka, Y1
Hashimoto, K1
Makino, H1
Blanco, C1
Maqueda, E1
Rubio, JA1
Rodriguez, A1
Shibata, H1
Ohmori, N2
Nomura, K2
Ohmori, K1
Takano, K2
Obinata, D1
Yamaguchi, K1
Hirano, D1
Yoshida, T1
Soma, M1
Takahashi, S1
Naruse, M1
Naruse, K1
Demura, H2
Shizume, K1
Schteingart, DE1
Tsao, HS1
Bertagna, C1
Orth, DN2
Wetterberg, L1
Badawy, SZ1
Notman, DD1
Sunderlin, FS1
Springer, JM1
Streeten, DH1
Omar, MM1
Marshall, LD1
Gormley, MJ1
Hadden, DR2
Kennedy, TL1
Montgomery, DA1
Murnaghan, GA1
Sheridan, B2
Zgliczyński, S1
Laws, ER1
Abboud, CF1
Kern, EB1
Cassar, J1
Loizou, S1
Kelly, WF1
Mashiter, K1
Joplin, GF1
Freeman, DA1
Auzéby, A1
Bogdan, A1
Touitou, Y1
Suda, T1
Tozawa, F1
Dobashi, I1
Horiba, N1
Yamakado, M1
Yamada, M1
Cuneo, RC1
Lee, W1
Harper, J1
Mitchell, K1
Ward, G1
Atkinson, RL1
Salkield, I1
Cameron, DP1
Kainz, G1
Mammone, J1
Outwater, EK1
Courtney, CH1
McAllister, AS1
McCance, DR1
Leslie, H1
Atkinson, AB1
Shimizu, C1
Yamane, Y1
Ishizuka, T1
Kijima, H1
Takano, A1
Kubo, M1
Koike, T1
Besser, GM2
Jeffcoate, WJ1
Jaquet, P1
Grisoli, F1
Guibout, M1
Lissitzky, JC1
Carayon, P1
Schnall, AM1
Brodkey, JS1
Kaufman, B1
Pearson, OH1
Tecilazich, D1
Rosenwirth, D1
Tonini, G1
Mangiarotti-Marchi, MA1
Delaney, JP1
Solomkin, JS1
Jacobson, ME1
Doe, RP1
Turpin, G1
Heshmati, HM1
Roger, M1
Legrand, S1
Guillemant, S1
de Gennes, JL1
Liddle, GW2
Wiedemann, E1
Saito, T1
Linfoot, JA1
Li, CH1
Britton, S1
Thorén, M1
Sjoberg, HE1
Green, JR1
van't Hoff, W1
Carballeira, A2
Fishman, LM2
Jacobi, JD1
Kato, S1
Masunaga, R1
Kawabe, T1
Nagasaka, A1
Miyamoto, T1
Itoh, M1
Nakai, A1
Iwase, K1
Tsujimura, T1
Ohtani, S1
Noritake, M1
Morimoto, K1
Kosano, H1
Nemoto, Y1
Kugai, N1
Takao, M1
Murai, M1
Tamai, S1
Tanaka, K1
Nagata, N1
Verhelst, JA1
Trainer, PJ1
Howlett, TA2
Perry, L1
Rees, LH2
Grossman, AB1
Wass, JA1
Fuhrman, SA1
Huiras, CM1
Pehling, GB1
Caplan, RH1
Nakashima, H1
Hirata, Y1
Uchihashi, M1
Tomita, M1
Fujita, T1
Laurberg, P1
Møller, J1
Husager, L1
Weeke, J1
Watanobe, H1
Kawagishi, T1
Hirai, Y1
Sato, T1
Tsutsui, M1
Kamata, Y1
Takebe, K1
Carpenter, PC1
Girard, J1
Eberle, AN1
Baumann, JB1
Else, W1
Meikle, AW2
Jubiz, W1
Matsukura, S1
Harada, G1
West, CD2
Tyler, FH3
Smilo, RP2
Earll, JM1
Forsham, PH2
Buckell, M1
Strott, CA1
Nugent, CA1
Materazzi, F1
Tucci, JR1
Espiner, EA1
Jagger, PI2
Lauler, DP2
Thorn, GW1
Pasqualini, JR1
Beuve-Méry, P1
Meyer, P1
Sparks, LL1
Pavlatos, FC1
Bethge, H1
Bayer, JM1
Winkelmann, W1
Pennington, LF1
Kreisberg, RA1
Hershman, JM1
Weiss, ER1
Rayyis, SS1
Nelson, DH1
Bethune, JE1
Crystal, RG1
Rose, LI1
Bricaire, H1
Luton, JP1
Yuji, S1
Nakajima, T1
Watanabe, A1
Yamada, S1
Uozumi, T1
Mori, S1
Watanabe, M1
Takimoto, N1
Mogami, H1
Lagerquist, LG1
Cheng, SC1
Matthews, JI1
Fariss, BL1
Chertow, BS1
Howard, WB1
Jones, JE1
Graham, NA1
Seal, US1
Tada, T1
Sprunt, JG1
Hannah, DM1
Loridan, L1
Senior, B1

Reviews

7 reviews available for metyrapone and Adenoma, Basal Cell

ArticleYear
Rationale for treatment and therapeutic options in Cushing's disease.
    Best practice & research. Clinical endocrinology & metabolism, 2009, Volume: 23 Suppl 1

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenalectomy; Choice Behavior; Combined Modality Therapy

2009
New prospects for drug treatment in Cushing disease.
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2012, Volume: 59, Issue:10

    Topics: Adenoma; Adrenocorticotropic Hormone; Animals; Cabergoline; Clinical Trials as Topic; Clinical Trial

2012
[Corticosterone-producing adrenal tumor].
    Nihon rinsho. Japanese journal of clinical medicine, 2006, May-28, Volume: Suppl 1

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Corticosterone; Diagnosis, Differential; Humans; Hy

2006
The relationship between the pineal gland and the pituitary--adrenal axis in health, endocrine and psychiatric conditions.
    Psychoneuroendocrinology, 1983, Volume: 8, Issue:1

    Topics: Adenoma; Adrenal Cortex Function Tests; Adrenocorticotropic Hormone; Circadian Rhythm; Cushing Syndr

1983
Appropriate laboratory testing in the screening and work-up of Cushing's syndrome.
    American journal of clinical pathology, 1988, Volume: 90, Issue:3

    Topics: Adenoma; Adrenocorticotropic Hormone; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethaso

1988
Is it possible to diagnose pituitary-dependent Cushing's disease?
    Annals of clinical biochemistry, 1985, Volume: 22 ( Pt 6)

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotropic Hor

1985
Cushing's syndrome: update of diagnosis and management.
    Mayo Clinic proceedings, 1986, Volume: 61, Issue:1

    Topics: Adenoma; Adrenal Glands; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Cushin

1986

Trials

2 trials available for metyrapone and Adenoma, Basal Cell

ArticleYear
Effect of estrogen on the metabolism of metyrapone and release of ACTH.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Chl

1970
Experience with a rapid oral metyrapone test and the plasma ACTH content in determining the cause of Cushing's syndrome.
    Metabolism: clinical and experimental, 1969, Volume: 18, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adolescent; Adrenal Gland Diseases; Adrenal Gla

1969

Other Studies

77 other studies available for metyrapone and Adenoma, Basal Cell

ArticleYear
ENDOCRINOLOGY IN THE TIME OF COVID-19: Management of Cushing's syndrome.
    European journal of endocrinology, 2020, Volume: 183, Issue:1

    Topics: 14-alpha Demethylase Inhibitors; ACTH-Secreting Pituitary Adenoma; Adenoma; Coronavirus Infections;

2020
Successful management of a patient with active Cushing's disease complicated with coronavirus disease 2019 (COVID-19) pneumonia.
    Endocrine journal, 2021, Apr-28, Volume: 68, Issue:4

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adult; Amides; Benzamidines; Combined Modality Therapy; C

2021
BIOCHEMICAL CONTROL DURING LONG-TERM FOLLOW-UP OF 230 ADULT PATIENTS WITH CUSHING DISEASE: A MULTICENTER RETROSPECTIVE STUDY.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2017, Volume: 23, Issue:8

    Topics: 14-alpha Demethylase Inhibitors; ACTH-Secreting Pituitary Adenoma; Adenoma; Adolescent; Adrenalectom

2017
[Indications and future perspectives in the pharmacological treatment of hypercortisolism].
    Recenti progressi in medicina, 2016, Volume: 107, Issue:3

    Topics: Adenoma; Cushing Syndrome; Humans; Hydrocortisone; Italy; Ketoconazole; Metyrapone; Pituitary Neopla

2016
Type 2 diabetes identified in pregnancy secondary to Cushing's syndrome.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2011, Volume: 31, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adult; Cushing Syndrome; Diabetes Mellitus, Type 2

2011
The use of an early postoperative CRH test to assess adrenal function after transsphenoidal surgery for pituitary adenomas.
    Pituitary, 2012, Volume: 15, Issue:3

    Topics: Adenoma; Adolescent; Adrenal Insufficiency; Adult; Aged; Aged, 80 and over; Corticotropin-Releasing

2012
[Predictors of long-term remission after transsphenoidal surgery in Cushing's disease].
    Endocrinologia y nutricion : organo de la Sociedad Espanola de Endocrinologia y Nutricion, 2013, Volume: 60, Issue:8

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adolescent; Adrenal Insufficiency; Adrenocorticotropic Ho

2013
Cushing's syndrome during pregnancy: curative adrenalectomy at 31 weeks gestation.
    European journal of obstetrics, gynecology, and reproductive biology, 2002, Nov-15, Volume: 105, Issue:2

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Cushing Syndrome; Female; Gestational A

2002
ASSESSMENT OF PITUITARY ACTH SECRETORY CAPACITY WITH METOPIRONE: 1. INTERPRETATION.
    The Journal of clinical endocrinology and metabolism, 1963, Volume: 23

    Topics: Acromegaly; Adenoma; Adenoma, Acidophil; Adenoma, Chromophobe; Adrenal Cortex Hormones; Adrenocortic

1963
ASSESSMENT OF PITUITARY ACTH SECRETORY CAPACITY WITH METOPIRONE: II. COMPARISON WITH OTHER TESTS.
    The Journal of clinical endocrinology and metabolism, 1963, Volume: 23

    Topics: Acromegaly; Adenoma; Adenoma, Chromophobe; Adrenal Cortex Hormones; Adrenocorticotropic Hormone; Art

1963
[SOME ASPECTS OF ENDOCRINE PROBLEMS AFTER EXCISION OF CHROMOPHOBE ADENOMAS].
    Nederlands tijdschrift voor geneeskunde, 1964, Jul-18, Volume: 108

    Topics: Adenoma; Adenoma, Chromophobe; Adrenocorticotropic Hormone; Ketones; Metyrapone; Mineralocorticoid R

1964
METYRAPONE AND PYROGEN IN THE ASSESSMENT OF PITUITARY-ADRENAL FUNCTION AFTER REMOVAL OF PITUITARY ADENOMA.
    Lancet (London, England), 1964, Nov-07, Volume: 2, Issue:7367

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenocorticotropic Hormone; Blood; Hypopituitarism; Ketones; Me

1964
MULTIPLE BRONCHIAL ADENOMAS, CUSHING'S SYNDROME AND HYPOKALEMIC ALKALOSIS. REPORT OF A CASE.
    Diseases of the chest, 1964, Volume: 46

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenalectomy; Adrenocorticotropic Hormone; Alk

1964
[A SURGICALLY TREATED CASE OF CONN'S SYNDROME. CLINICAL, HISTOLOGICAL AND BIOCHEMICAL FINDINGS].
    Schweizerische medizinische Wochenschrift, 1964, May-02, Volume: 94

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenalectomy; Alkalosis; Humans; Hyperal

1964
EFFECTS OF ADMINISTRATION OF METOPIRON AND OF DELIVERY ON HUMAN PLASMA CORTICOTROPHIN.
    Acta endocrinologica, 1965, Volume: 48

    Topics: Adenoma; Adenoma, Chromophobe; Adrenocorticotropic Hormone; Blood; Delivery, Obstetric; Female; Huma

1965
CLINICAL ASSESSMENT OF THE PERORAL METOPIRONE TEST.
    Acta medica Scandinavica, 1965, Volume: 178

    Topics: Adenoma; Adenoma, Chromophobe; Adrenalectomy; Adrenocorticotropic Hormone; Cushing Syndrome; Diabete

1965
Periodic secretion of adrenocorticotropin in a patient with Cushing's disease manifested during pregnancy.
    Endocrine journal, 2005, Volume: 52, Issue:3

    Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Corticotropin-Releasing Hormone; Female; Humans; Hydroc

2005
Cushing's syndrome during pregnancy secondary to adrenal adenoma: metyrapone treatment and laparoscopic adrenalectomy.
    Journal of endocrinological investigation, 2006, Volume: 29, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Cushing Syndrome; Enzyme Inhibitors; Female;

2006
Preclinical Cushing's disease characterized by massive adrenal hyperplasia and hormonal changes after three years of metyrapone therapy.
    Endocrine journal, 2007, Volume: 54, Issue:3

    Topics: ACTH-Secreting Pituitary Adenoma; Adenoma; Adrenal Glands; Adrenocorticotropic Hormone; Aged; Antime

2007
Preoperative management of Cushing's syndrome with metyrapone for severe psychiatric disturbances.
    International journal of urology : official journal of the Japanese Urological Association, 2008, Volume: 15, Issue:4

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Depressive Disorder; Female; Humans; Metyrapone; Mi

2008
In vivo evidence of cortisol secretion by aldosterone-producing adenomas.
    Acta endocrinologica, 1984, Volume: 106, Issue:4

    Topics: Adenoma; Adrenocorticotropic Hormone; Aldosterone; Humans; Hydrocortisone; Hyperaldosteronism; Metyr

1984
Coexistence of pituitary adrenocorticotropin-dependent Cushing's syndrome with a solitary adrenal adenoma.
    The Journal of clinical endocrinology and metabolism, 1980, Volume: 50, Issue:5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Cushing Syndrome; Dexamethasone; Fema

1980
Clinical and laboratory findings and results of therapy in 58 patients with adrenocortical tumors admitted to a single medical center (1951 to 1978).
    The American journal of medicine, 1981, Volume: 71, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Cortex Function Tests; Adrenal Cortex Neoplasms; Adrenocorticotropic Ho

1981
Hypothalamic-pituitary function following bromocriptine therapy in patients with prolactinomas.
    The Journal of reproductive medicine, 1982, Volume: 27, Issue:3

    Topics: Adenoma; Adult; Bromocriptine; Female; Humans; Hypothalamo-Hypophyseal System; Infertility, Female;

1982
Cushing's syndrome in pregnancy--treatment with metyrapone.
    Clinical endocrinology, 1982, Volume: 16, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Cushing Syndrome; Female; Humans; Metyrapone; Pregnancy; Pr

1982
[Cushing's syndrome: metyrapone therapy as a preparation for selective trans-sphenoidal adenomectomy].
    Endokrynologia Polska, 1982, Volume: 33, Issue:4-6

    Topics: Adenoma; Adolescent; Adult; Cushing Syndrome; Female; Humans; Male; Metyrapone; Middle Aged; Pituita

1982
Perioperative management of patients with pituitary microadenoma.
    Neurosurgery, 1980, Volume: 7, Issue:6

    Topics: Adenoma; Female; Humans; Hypopituitarism; Male; Metyrapone; Microsurgery; Pituitary Neoplasms; Posto

1980
Deoxycorticosterone and aldosterone excretion in Cushing's syndrome.
    Metabolism: clinical and experimental, 1980, Volume: 29, Issue:2

    Topics: Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenal Glands; Adult; Aged; Aldosterone; Carcinoma;

1980
Adrenal carcinoma.
    Current therapy in endocrinology and metabolism, 1994, Volume: 5

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Aminoglutethimide; Carcinoma; Cushing Syndrome; Dia

1994
An alternate pathway to androstenedione synthesis by human adrenals: evidence of a balance in 11 beta-hydroxylase and 17,20-lyase activities leading to androstenedione.
    The Journal of clinical endocrinology and metabolism, 1995, Volume: 80, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Adult

1995
Corticotropin-releasing hormone, proopiomelanocortin, and glucocorticoid receptor gene expression in adrenocorticotropin-producing tumors in vitro.
    The Journal of clinical investigation, 1993, Volume: 92, Issue:6

    Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Arginine

1993
Metyrapone pre-treated inferior petrosal sinus sampling in the differential diagnosis of ACTH-dependent Cushing's syndrome.
    Clinical endocrinology, 1997, Volume: 46, Issue:5

    Topics: ACTH Syndrome, Ectopic; Adenoma; Adolescent; Adrenocorticotropic Hormone; Adult; Cortodoxone; Cushin

1997
Change in the composition of adrenal nodules after therapy as revealed by opposed-phase MR imaging.
    AJR. American journal of roentgenology, 1997, Volume: 169, Issue:2

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Aged; Female; Humans; Magnetic Resonance Imaging;

1997
The insulin hypoglycaemia and overnight metyrapone tests in the assessment of the hypothalamic-pituitary-adrenal axis following pituitary surgery.
    Clinical endocrinology, 2000, Volume: 53, Issue:3

    Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Cortodoxone; Female; Follow-Up Studies; Humans; H

2000
Involvement of the cholinergic pathway in the pathogenesis of pituitary Cushing's syndrome.
    Endocrine journal, 2001, Volume: 48, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenocorticotropic Hormone; Atropine; Choline;

2001
Endocrine and metabolic diseases. Adrenal diseases.
    British medical journal, 1976, Feb-21, Volume: 1, Issue:6007

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Insuffici

1976
Prolactin secreting tumors. Endocrine status before and after surgery in 33 women.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 46, Issue:3

    Topics: Adenoma; Arginine; Female; Follicular Phase; Gonadotropin-Releasing Hormone; Growth Hormone; Humans;

1978
Pituitary function after removal of pituitary microadenomas in Cushing's disease.
    The Journal of clinical endocrinology and metabolism, 1978, Volume: 47, Issue:2

    Topics: 17-Ketosteroids; Adenoma; Adult; Cushing Syndrome; Follicle Stimulating Hormone; Humans; Hydrocortis

1978
[Auxological problems in a case of virilizing adenoma of the adrenal gland].
    Minerva pediatrica, 1977, Mar-24, Volume: 29, Issue:10

    Topics: 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Child; Child, Preschool; Dexamethasone; Growth Di

1977
Surgical management of Cushing's syndrome.
    Surgery, 1978, Volume: 84, Issue:4

    Topics: Adenoma; Adolescent; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocorticotropic Ho

1978
[Adrenocortical function in hyperprolactinemia. The study of glucocorticoids, mineralocorticoids and androgens in chronic and acute hyperprolactinemias (author's transl)].
    Annales d'endocrinologie, 1979, Volume: 40, Issue:6

    Topics: Acute Disease; Adenoma; Adrenal Cortex; Adrenocorticotropic Hormone; Androgens; Chronic Disease; Fem

1979
Cushing's syndrome.
    Annals of the New York Academy of Sciences, 1977, Oct-28, Volume: 297

    Topics: Adenoma; Corticotropin-Releasing Hormone; Cushing Syndrome; Dexamethasone; Humans; Metyrapone; Pitui

1977
Specific radioimmunoassay of human beta-endorphin in unextracted plasma.
    The Journal of clinical endocrinology and metabolism, 1979, Volume: 49, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Carcinoma, Bronchogenic; Cushing Syndrome; Dexamethasone; Endorphi

1979
The immunological hazard of Cushing's syndrome.
    British medical journal, 1975, Dec-20, Volume: 4, Issue:5998

    Topics: Adenoma; Adrenal Gland Neoplasms; Adult; Cryptococcosis; Cushing Syndrome; Female; Fluorouracil; Hum

1975
Cushing's syndrome with fluctuation due to adrenal adenoma.
    The Journal of clinical endocrinology and metabolism, 1975, Volume: 41, Issue:2

    Topics: 11-Hydroxycorticosteroids; 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Circadian Rh

1975
Dual sites of inhibition by metyrapone of human adrenal steroidogenesis: correlation of in vivo and in vitro studies.
    The Journal of clinical endocrinology and metabolism, 1976, Volume: 42, Issue:4

    Topics: Adenoma; Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adrenoco

1976
Cushing's syndrome induced by hypersecretion of cortisol from only one of bilateral adrenocortical tumors.
    Metabolism: clinical and experimental, 1992, Volume: 41, Issue:3

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Cortex Neoplasms; Adult; Cosyntropin; Cushing Syndrome; De

1992
A case of asymptomatic cortisol producing adrenal adenoma.
    Endocrinologia japonica, 1992, Volume: 39, Issue:1

    Topics: Adenoma; Adrenal Gland Neoplasms; Cushing Syndrome; Dexamethasone; Humans; Hydrocortisone; Hypothala

1992
Short and long-term responses to metyrapone in the medical management of 91 patients with Cushing's syndrome.
    Clinical endocrinology, 1991, Volume: 35, Issue:2

    Topics: ACTH Syndrome, Ectopic; Adenoma; Adolescent; Adrenal Cortex Neoplasms; Adrenocorticotropic Hormone;

1991
Adrenal insufficiency after operative removal of apparently nonfunctioning adrenal adenomas.
    JAMA, 1989, Feb-10, Volume: 261, Issue:6

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Insufficiency; Adrenalectomy; Dex

1989
Effect of ovine corticotrophin releasing factor, bromocriptine, and dopamine on release of ACTH and beta-endorphin in a patient with Cushing's disease.
    Acta endocrinologica, 1985, Volume: 109, Issue:1

    Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Animals; beta-Endorphin; Bromocriptine; Corticotropin-R

1985
Evaluation of pituitary-adrenal function after pituitary surgery.
    Scandinavian journal of clinical and laboratory investigation, 1985, Volume: 45, Issue:4

    Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Cortodoxone; Cranio

1985
Cushing's syndrome presenting the coexistence of a pituitary corticotrophic cell hyperplasia and a unilateral functional adrenal adenoma.
    Acta endocrinologica, 1985, Volume: 110, Issue:3

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Circadian Rhythm; Cush

1985
Plasma ACTH in diagnosis and control of adrenal disorders.
    Acta endocrinologica. Supplementum, 1986, Volume: 279

    Topics: 17-alpha-Hydroxyprogesterone; Adenoma; Adrenal Gland Diseases; Adrenal Hyperplasia, Congenital; Adre

1986
Pituitary-adrenal function tests in patients with untreated pituitary tumours.
    Lancet (London, England), 1968, Nov-02, Volume: 2, Issue:7575

    Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Aged; Cerebral Ventriculography; Female; Humans; Hydroc

1968
Suppression of tumorous adrenal hyperfunction by aminoglutethimide.
    Metabolism: clinical and experimental, 1967, Volume: 16, Issue:4

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocortical Hyperfu

1967
Endocrine function following treatment of pituitary adenoma.
    Acta endocrinologica, 1967, Volume: 55, Issue:1

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Adenoma; Adrenocorticotropic Hormone; Adult; Basal Metab

1967
Cushing's syndrome caused by bronchial adenomas.
    The American journal of medicine, 1968, Volume: 44, Issue:1

    Topics: Adenoma; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Biological Assay; Bronchial Neoplasms; C

1968
[Reichstein's S substance in humans].
    Recenti progressi in medicina, 1966, Volume: 41, Issue:6

    Topics: Adenocarcinoma; Adenoma; Adrenal Cortex Hormones; Adrenal Gland Diseases; Adrenal Gland Neoplasms; A

1966
Vasopressin in the evaluation of pituitary-adrenal function.
    Annals of internal medicine, 1968, Volume: 69, Issue:2

    Topics: Acromegaly; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Anorex

1968
[Production and excretion of corticosteroids in primary hyperaldosteronism].
    Pathologie et biologie, 1968, Volume: 16, Issue:9

    Topics: Adenoma; Adrenal Cortex Hormones; Angiotensin II; Carbon Isotopes; Dexamethasone; Humans; Hyperaldos

1968
Diagnosis of Cushing's syndrome. The differentiation between adrenocortical hyperplasia and adrenocrotical adenoma by means of lysine-vasopressin.
    Acta endocrinologica, 1969, Volume: 60, Issue:1

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone

1969
Anomalous response to metyrapone in Cushing's syndrome due to adrenocortical adenoma.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 30, Issue:1

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Cus

1970
Evaluation of stimulation and suppression tests in the etiological diagnosis of Cushing's syndrome.
    Annals of internal medicine, 1969, Volume: 71, Issue:5

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Ang

1969
Cushing's syndrome caused by a metyrapone responsive adrenocortical adenoma.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 31, Issue:2

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Horm

1970
[Poly-micro-adenomatosis in Cushing's syndrome].
    La Presse medicale, 1970, Oct-17, Volume: 78, Issue:43

    Topics: Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Cushing Syndr

1970
[Radioimmunoassay of ACTH].
    Nihon Naibunpi Gakkai zasshi, 1971, May-20, Volume: 47, Issue:2

    Topics: 17-Hydroxycorticosteroids; Addison Disease; Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Ho

1971
Results of treatment in 108 patients with Cushing's syndrome.
    The New England journal of medicine, 1971, Jul-29, Volume: 285, Issue:5

    Topics: Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adrenocorticotropic Hormone; Adult; Age

1971
[Urinary 6beta-hydroxycortisol. II. Urinary 6beta-hydroxycortisol in different diseases and after administration of drugs].
    Nihon Naibunpi Gakkai zasshi, 1973, Jun-20, Volume: 49, Issue:6

    Topics: Adenoma; Adrenal Gland Neoplasms; Adrenocorticotropic Hormone; Adult; Carcinoma; Cushing Syndrome; F

1973
[Endocrinological evaluation of sellar and suprasellar tumor cases --the first report-- on preoperative pituitary function (author's transl)].
    No shinkei geka. Neurological surgery, 1974, Volume: 2, Issue:5

    Topics: Adenoma; Adolescent; Adrenocorticotropic Hormone; Adult; Brain Neoplasms; Child; Chordoma; Craniopha

1974
Cushing's disease with cure by resection of a pituitary adenoma. Evidence against a primary hypothalamic defect.
    The American journal of medicine, 1974, Volume: 57, Issue:5

    Topics: Adenoma; Adrenocorticotropic Hormone; Adult; Circadian Rhythm; Cushing Syndrome; Depression, Chemica

1974
Metabolism of (4-14C) cholesterol by human adrenal glands in vitro and its inhibition by metyrapone.
    Acta endocrinologica, 1974, Volume: 76, Issue:4

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Diseases; Adrenal Gland Neoplasms; Adrenal Glands;

1974
Adrenal adenoma with variable response to dexamethasone suppression and metyrapone stimulation.
    The Journal of clinical endocrinology and metabolism, 1972, Volume: 34, Issue:5

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Hyperfun

1972
Excretion of urinary free amino acids in Cushing's syndrome.
    The Journal of clinical endocrinology and metabolism, 1969, Volume: 29, Issue:12

    Topics: 17-Hydroxycorticosteroids; Adenoma; Adolescent; Adrenal Gland Neoplasms; Adrenalectomy; Adult; Amino

1969
[Clinical studies on urinary 17-ketogenic steroid fractions. 3. SU-4885 test in normal subjects and the patients with various endocrine disorders].
    Nihon Naibunpi Gakkai zasshi, 1968, Mar-20, Volume: 43, Issue:12

    Topics: 17-Hydroxycorticosteroids; Acromegaly; Adenoma; Adolescent; Adrenal Cortex Hormones; Adrenal Gland N

1968
A comparison of of the potency of some 11beta-hydroxylase inhibitors using rat and human adrenal tissue.
    The Journal of endocrinology, 1968, Volume: 41, Issue:4

    Topics: Adenoma; Adrenal Cortex Hormones; Adrenal Gland Neoplasms; Adrenal Glands; Animals; Carbon Isotopes;

1968
Cushing's syndrome in infancy.
    The Journal of pediatrics, 1969, Volume: 75, Issue:3

    Topics: 17-Hydroxycorticosteroids; 17-Ketosteroids; Abnormalities, Multiple; Adenoma; Adrenal Gland Neoplasm

1969