metyrapone has been researched along with Absence Seizure Disorder in 1 studies
Metyrapone: An inhibitor of the enzyme STEROID 11-BETA-MONOOXYGENASE. It is used as a test of the feedback hypothalamic-pituitary mechanism in the diagnosis of CUSHING SYNDROME.
metyrapone : An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Metyrapone, an inhibitor of corticosterone synthesis, completely abolished seizures in GAERS, and seizures remained suppressed for >2 h." | 8.31 | Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones. ( Dezsi, G; Harris, G; Jones, NC; O'Brien, TJ; Ozturk, E; Paul, C, 2023) |
| " Metyrapone, an inhibitor of corticosterone synthesis, completely abolished seizures in GAERS, and seizures remained suppressed for >2 h." | 4.31 | Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones. ( Dezsi, G; Harris, G; Jones, NC; O'Brien, TJ; Ozturk, E; Paul, C, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dezsi, G | 1 |
| Ozturk, E | 1 |
| Harris, G | 1 |
| Paul, C | 1 |
| O'Brien, TJ | 1 |
| Jones, NC | 1 |
1 other study available for metyrapone and Absence Seizure Disorder
| Article | Year |
|---|---|
Metyrapone abolishes spike-wave discharge seizures in genetic absence epilepsy rats from Strasbourg by reducing stress hormones.
Topics: Animals; Corticosterone; Desoxycorticosterone; Disease Models, Animal; Electroencephalography; Epile | 2023 |