metronidazole has been researched along with Weight Gain in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Weight Gain: Increase in BODY WEIGHT over existing weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The atypical antipsychotic olanzapine is often associated with serious metabolic side effects including weight gain and increased visceral fat." | 3.79 | Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat. ( Cotter, PD; Crispie, F; Cryan, JF; Davey, KJ; Dinan, TG; O'Mahony, SM; O'Sullivan, O, 2013) |
| " Therapy with metronidazole and a high-protein diet resulted in satisfactory weight gain and cessation of the diarrhea." | 3.68 | Weanling diarrhea: a case report. ( Bulux, J; Molina, S; Solomons, NW, 1990) |
| "Colitis was ameliorated by oral administration of broad-spectrum antibiotics." | 1.35 | Colonic gene expression profile in NHE3-deficient mice: evidence for spontaneous distal colitis. ( Bai, A; Ghishan, FK; Kiela, PR; Larmonier, CB; Laubitz, D; Lipko, MA; Midura-Kiela, MT; Thurston, RD, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davey, KJ | 1 |
| Cotter, PD | 1 |
| O'Sullivan, O | 1 |
| Crispie, F | 1 |
| Dinan, TG | 1 |
| Cryan, JF | 1 |
| O'Mahony, SM | 1 |
| Butler, MM | 1 |
| Shinabarger, DL | 1 |
| Citron, DM | 1 |
| Kelly, CP | 1 |
| Dvoskin, S | 1 |
| Wright, GE | 1 |
| Feng, H | 1 |
| Tzipori, S | 1 |
| Bowlin, TL | 1 |
| Laubitz, D | 1 |
| Larmonier, CB | 1 |
| Bai, A | 1 |
| Midura-Kiela, MT | 1 |
| Lipko, MA | 1 |
| Thurston, RD | 1 |
| Kiela, PR | 1 |
| Ghishan, FK | 1 |
| Lichtman, SN | 1 |
| Wang, J | 1 |
| Sartor, RB | 1 |
| Zhang, C | 1 |
| Bender, D | 1 |
| Dalldorf, FG | 1 |
| Schwab, JH | 1 |
| Hegngi, FN | 1 |
| Doerr, J | 1 |
| Cummings, TS | 1 |
| Schwartz, RD | 1 |
| Saunders, G | 1 |
| Zajac, A | 1 |
| Larsen, CT | 1 |
| Pierson, FW | 1 |
| Solomons, NW | 1 |
| Molina, S | 1 |
| Bulux, J | 1 |
6 other studies available for metronidazole and Weight Gain
| Article | Year |
|---|---|
Antipsychotics and the gut microbiome: olanzapine-induced metabolic dysfunction is attenuated by antibiotic administration in the rat.
Topics: Animals; Anti-Bacterial Agents; Antipsychotic Agents; Benzodiazepines; Fatty Acids, Nonesterified; F | 2013 |
MBX-500, a hybrid antibiotic with in vitro and in vivo efficacy against toxigenic Clostridium difficile.
Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Clostridioides difficile; Cricetinae; DNA Gyrase | 2012 |
Colonic gene expression profile in NHE3-deficient mice: evidence for spontaneous distal colitis.
Topics: Animals; Anti-Infective Agents; Ciprofloxacin; Colitis; Colon; Gene Deletion; Gene Expression Profil | 2008 |
Reactivation of arthritis induced by small bowel bacterial overgrowth in rats: role of cytokines, bacteria, and bacterial polymers.
Topics: Animals; Ankle Joint; Arthritis, Reactive; Cytokines; Female; Intestine, Small; Lipopolysaccharides; | 1995 |
The effectiveness of benzimidazole derivatives for the treatment and prevention of histomonosis (blackhead) in turkeys.
Topics: Albendazole; Animals; Anthelmintics; Cecum; Female; Fenbendazole; Liver; Metronidazole; Poultry Dise | 1999 |
Weanling diarrhea: a case report.
Topics: Animals; Diarrhea; Dietary Proteins; Giardiasis; Guatemala; Humans; Infant; Kwashiorkor; Male; Metro | 1990 |