metronidazole has been researched along with Vulvovaginitis in 53 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Vulvovaginitis: Inflammation of the VULVA and the VAGINA, characterized by discharge, burning, and PRURITUS.
Excerpt | Relevance | Reference |
---|---|---|
"Vulvovaginitis is the most observed genital disease in children and adolescents and dependent from different etiologic factors." | 5.27 | [Treatment of vulvovaginitis in children and adolescents with metronidazole]. ( Amon, K; Scharp, H, 1984) |
" For this reason, the present study was conducted to investigate the effectiveness of octenidine dihydrochloride/phenoxyethanol (OHP) in comparison to antimicrobial therapies in pregnant women in hospital suffering from different types of vaginitis." | 3.81 | Study results on the use of different therapies for the treatment of vaginitis in hospitalised pregnant women. ( Novakov Mikić, A; Stojic, S, 2015) |
"Vulvovaginal candidiasis affects 75% of women at least once." | 1.42 | Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis. ( van Schalkwyk, J; Yudin, MH, 2015) |
"Vulvovaginitis is the most observed genital disease in children and adolescents and dependent from different etiologic factors." | 1.27 | [Treatment of vulvovaginitis in children and adolescents with metronidazole]. ( Amon, K; Scharp, H, 1984) |
" The dosage of metronidazole was about 10 or 20 mg/kg b." | 1.27 | Disposition kinetics of metronidazole in children. ( Amon, I; Amon, K; Franke, G; Nagel, F; Scharp, H, 1983) |
"Metronidazole was used only for resistant cases of trichomoniasis, with a cure rate of over 80% when both partners were treated simultaneously." | 1.24 | CLINICAL TRIALS WITH AGENTS CURRENTLY USED IN THE MANAGEMENT OF VAGINITIS. ( O'BRIEN, JR, 1964) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 45 (84.91) | 18.7374 |
1990's | 4 (7.55) | 18.2507 |
2000's | 2 (3.77) | 29.6817 |
2010's | 2 (3.77) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Novakov Mikić, A | 1 |
Stojic, S | 1 |
van Schalkwyk, J | 1 |
Yudin, MH | 1 |
Lo, M | 1 |
Reid, M | 1 |
Brokenshire, M | 1 |
COSAR, C | 1 |
GANTER, P | 1 |
JULOU, L | 1 |
FORTIN, PE | 1 |
GAUVREAU, L | 1 |
GRAY, LA | 2 |
KOTCHER, E | 1 |
GIESEL, LO | 1 |
DE ROM, R | 1 |
THIERY, M | 1 |
VAN SWIJNDREGT, LM | 1 |
DASKALIDES, J | 1 |
DUREL, P | 1 |
COUTURE, J | 1 |
COLLART, P | 1 |
GIROT, C | 1 |
POPKHRISTOV, P | 1 |
BEROV, V | 1 |
LAMBILLON, J | 1 |
WATT, L | 2 |
JENNISON, RF | 2 |
GRAY, MS | 1 |
SCHRAM, M | 1 |
KLEINMAN, H | 1 |
IGLOE, MC | 1 |
KARNAKY, KJ | 1 |
STREETER, RT | 1 |
WEST, WT | 1 |
RUSSO, A | 1 |
MACCHIONI, B | 1 |
WALL, JA | 1 |
JAKOBOVITS, A | 1 |
SZELL, I | 1 |
GARDNER, HL | 1 |
FERNET, P | 1 |
O'BRIEN, JR | 1 |
NAGEL, J | 1 |
LATUFF, H | 1 |
YAMIN, G | 1 |
DEFIGUEROA, E | 1 |
PHILIPP, EE | 1 |
BARNES, ML | 1 |
MOFFETT, M | 1 |
MCGILL, MI | 1 |
JAMESON, WJ | 1 |
KANE, PO | 2 |
McFADZEAN, JA | 2 |
SQUIRES, S | 2 |
KING, AJ | 1 |
NICOL, CS | 1 |
KUNZ, L | 1 |
HAUSER, GA | 1 |
LUNDSTROM, P | 1 |
PERL, G | 1 |
RAGAZZONI, H | 1 |
RINDI, V | 1 |
MASCIADRI GASBARRO, O | 1 |
Sheeley, A | 1 |
Sander, C | 1 |
Lossick, JG | 1 |
Scharp, H | 2 |
Amon, K | 2 |
Amon, I | 1 |
Franke, G | 1 |
Nagel, F | 1 |
Tatár, L | 1 |
Fleury, FJ | 1 |
Citronberg, RJ | 1 |
Semel, JD | 1 |
Sullivan, C | 1 |
Smith, LG | 1 |
Lanta, S | 1 |
Mention, JE | 1 |
Schubert, W | 1 |
Sikorski, R | 1 |
Hencner, Z | 1 |
Gliński, Z | 1 |
Wawrzkiewicz, K | 1 |
Radomański, T | 1 |
Milart, P | 1 |
Paszkowski, T | 1 |
Skrzypczak, W | 1 |
Sławiński, P | 1 |
Maruszak, E | 1 |
Schneider, GT | 1 |
Geary, WL | 1 |
Dennerstein, GJ | 1 |
Beaton, JH | 1 |
Berić, B | 1 |
Bregun-Dragić, N | 1 |
Popović, D | 1 |
Stretenović, Z | 1 |
Grimmer, H | 1 |
Kurnatowska, A | 1 |
Landes, E | 1 |
5 reviews available for metronidazole and Vulvovaginitis
Article | Year |
---|---|
Sorting out common causes of abnormal vaginal discharge.
Topics: Anti-Infective Agents; Female; Humans; Hydrogen-Ion Concentration; Metronidazole; Patient Education | 2004 |
Sexually transmitted vaginitis.
Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Female; Gardnerella vaginalis; Haemophilus Infections; | 1984 |
Severe vaginal infection with Entamoeba histolytica in a woman who recently returned from Mexico: case report and review.
Topics: Aged; Animals; Entamoeba histolytica; Entamoebiasis; Female; Humans; Iodoquinol; Metronidazole; Mexi | 1995 |
Management of vulvovaginitis in pregnancy.
Topics: Acyclovir; Anti-Bacterial Agents; Cesarean Section; Female; Gynecology; Humans; Incidence; Laser The | 1993 |
Vaginitis: diagnosis and treatment.
Topics: Adult; Candidiasis; Clinical Laboratory Techniques; Diagnosis, Differential; Female; Haemophilus Inf | 1972 |
1 trial available for metronidazole and Vulvovaginitis
Article | Year |
---|---|
[Microbiological evaluation of the effectiveness of gynalgin in the treatment of vaginitis].
Topics: Animals; Anti-Infective Agents, Local; Antifungal Agents; Antitrichomonal Agents; Bacterial Infectio | 1992 |
47 other studies available for metronidazole and Vulvovaginitis
Article | Year |
---|---|
Study results on the use of different therapies for the treatment of vaginitis in hospitalised pregnant women.
Topics: Adolescent; Adult; Anti-Infective Agents; Candidiasis, Vulvovaginal; Ethylene Glycols; Female; Human | 2015 |
Vulvovaginitis: screening for and management of trichomoniasis, vulvovaginal candidiasis, and bacterial vaginosis.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Canada; Candidiasis, Vulvovaginal; Clindamycin; Female | 2015 |
Resistance of Trichomonas vaginalis infections to metronidazole in Auckland sexual health clinics: report of two cases.
Topics: Administration, Intravaginal; Administration, Oral; Adult; Ambulatory Care Facilities; Animals; Anti | 2002 |
[Experimental study on metronidazole (RP-8823. Trichomonacidal and amebicidal activities. Toxicity and general pharmacological properties].
Topics: Amebicides; Female; Humans; Imidazoles; Metronidazole; Trichomonas Infections; Vaginitis; Vulvovagin | 1961 |
[Effective treatment of Trichomonas vaginitis by metronidazole].
Topics: Female; Humans; Imidazoles; Metronidazole; Treatment Outcome; Trichomonas Infections; Trichomonas Va | 1961 |
Evaluation of a systemic drug, a nitro-imidazole ("Flagyl") in the treatment of trichomoniasis.
Topics: Female; Humans; Imidazoles; Metronidazole; Trichomonas Infections; Vaginitis; Vulvovaginitis | 1961 |
[Metronidazole. Oral chemotherapy of vaginal trichomoniasis].
Topics: Female; Humans; Imidazoles; Metronidazole; Trichomonas Infections; Trichomonas Vaginitis; Vaginitis; | 1961 |
Flagyl (metronidazole).
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Trichomonas Infections; Vagini | 1960 |
[On treatment of urethritis and vaginitis caused by Trichomonas vaginalis with the imidazole preparation flagyl].
Topics: Female; Humans; Imidazoles; Metronidazole; Trichomonas Infections; Trichomonas vaginalis; Urethritis | 1961 |
[An imidazole derivative, Flagyl, a treatment of genital trichomoniasis].
Topics: Female; Humans; Imidazoles; Metronidazole; Trichomonas Infections; Vaginitis; Vulvovaginitis | 1961 |
Clinical evaluation of metronidazole. A new systemic trichomonacide.
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Trichomonas Infections; Vagini | 1960 |
Trichomonas vaginalis in pregnancy: the results of metronidazole therapy on the mother and child.
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Mothers; Pregnancy; Trichomona | 1961 |
Use of metronidazole in the treatment of trichomoniasis.
Topics: Female; Humans; Imidazoles; Metronidazole; Trichomonas Infections; Vaginitis; Vulvovaginitis | 1962 |
Evaluation of metronidazole therapy for Trichomonas vaginalis vaginitis.
Topics: Female; Humans; Imidazoles; Metronidazole; Trichomonas vaginalis; Trichomonas Vaginitis; Vaginitis; | 1963 |
Metronidazole.
Topics: Antiparasitic Agents; Female; Humans; Imidazoles; Leukopenia; Metronidazole; Trichomonas Infections; | 1962 |
Metronidazole; an effective oral medication for the treatment of Trichomonas vaginalis vaginitis.
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Trichomonas vaginalis; Trichom | 1963 |
Vaginitis therapy evaluated. The treatment of trichomonal vaginitis with metronidazole.
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Trichomonas Vaginitis; Vaginit | 1963 |
Metronidazole treatment of trichomoniasis in the female. Report of an extended trial.
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Trichomonas Infections; Vagini | 1962 |
[Systemic therapy of female genital trichomoniasis with an imidazole derivative (metronidazole)].
Topics: Female; Humans; Imidazoles; Metronidazole; Trichomonas Infections; Vaginitis; Vulvovaginitis | 1961 |
THE TREATMENT OF TRICHOMONAS VAGINALIS VAGINITIS.
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Trichomonas vaginalis; Trichom | 1963 |
[PATHOLOGY OF VAGINITIS CAUSED BY TRICHOMONAL INFECTION].
Topics: Colposcopy; Erythrocytes; Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Mono | 1963 |
ETIOLOGY OF VAGINITIS EMPHYSEMATOSA: REPORT OF TEN CASES AND REVIEW OF LITERATURE.
Topics: Clioquinol; Female; Furazolidone; Haemophilus; Humans; Imidazoles; Metronidazole; Trichomonas Vagini | 1964 |
CLINICAL TRIALS WITH AGENTS CURRENTLY USED IN THE MANAGEMENT OF VAGINITIS.
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Antifungal Agents; Atrophic Vaginitis; Bacterial | 1964 |
[PREPUBERAL VULVOVAGINITIS].
Topics: Anti-Bacterial Agents; Antibiotics, Antitubercular; Candidiasis, Vulvovaginal; Child; Female; Humans | 1964 |
VULVO-VAGINITIS.
Topics: Adolescent; Candidiasis, Vulvovaginal; Child; Diabetes Mellitus; Drug Therapy; Female; Gonorrhea; Hu | 1965 |
VAGINITIS IN WOMEN, DIAGNOSIS AND TREATMENT.
Topics: Antifungal Agents; Candidiasis, Vulvovaginal; Diagnosis; Drug Therapy; Female; Haemophilus; Humans; | 1965 |
Treatment of trichomoniasis with metronidazole.
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Trichomonas Infections; Vagini | 1960 |
Clinical effectiveness of potent trichomonacide, metronidazole.
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Treatment Outcome; Trichomonas | 1962 |
Absorption and excretion of metronidazole. I. Serum concentration and urinary excretion after oral administration.
Topics: Administration, Oral; Biological Transport; Female; Humans; Imidazoles; Metronidazole; Trichomonas I | 1961 |
Absorption and excretion of metronidazole. II. Studies on primary failures.
Topics: Biological Transport; Female; Humans; Imidazoles; Metronidazole; Trichomonas Infections; Vaginitis; | 1961 |
[Trichomonas vaginitis and its treatment with Flagyl].
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Trichomonas Vaginitis; Vaginit | 1962 |
[Trichomoniasis in humans-particularly socalled Trichomonas vaginitis-with special reference to a tendency toward spontaneous healing and to treatment with Flagyl].
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Trichomonas Infections; Tricho | 1961 |
Flagyl in treatment of "Trichomonas vaginalis" vaginitis.
Topics: Female; Humans; Imidazoles; Metronidazole; Trichomonas Infections; Trichomonas vaginalis; Vaginitis; | 1962 |
[Evaluation of the pharmacotherapeutic power of metrodinazole (Flagyl) in female trichomoniasis].
Topics: Female; Humans; Imidazoles; Intraabdominal Infections; Metronidazole; Trichomonas Infections; Vagini | 1961 |
[Purulent vulvovaginitis in a newborn girl as a rare form of a trichomonas vaginalis infection and its treatment].
Topics: Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Metronidazole; Pregnancy; Trichomonas Va | 1967 |
[Treatment of vulvovaginitis in children and adolescents with metronidazole].
Topics: Adolescent; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Child; Child, Preschool; F | 1984 |
Disposition kinetics of metronidazole in children.
Topics: Adolescent; Aging; Body Weight; Child; Child, Preschool; Drug Administration Schedule; Female; Human | 1983 |
Observations made with the simultaneous local application of metronidazole and miconazole in vulvovaginitis.
Topics: Adult; Drug Combinations; Female; Humans; Metronidazole; Miconazole; Middle Aged; Vulvovaginitis | 1982 |
Adult vaginitis.
Topics: Atrophy; Female; Haemophilus Infections; Humans; Metronidazole; Trichomonas Vaginitis; Uterine Cervi | 1981 |
[Leukorrhea: diagnostic trends].
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Antifungal Agents; Antitricho | 1999 |
[Candida and trichomonas infections. Character and frequency of vulvovaginal inflammations in gynecologic practice and their treatment].
Topics: Candida albicans; Female; Humans; Metronidazole; Nystatin; Trichomonas; Vulvovaginitis | 1979 |
Vaginitis in adolescent girls.
Topics: Adolescent; Boric Acids; Candida; Candidiasis, Vulvovaginal; Child; Enterobius; Female; Foreign Bodi | 1971 |
An aggressive plan for the treatment of vulvovaginitis.
Topics: Diethylstilbestrol; Female; Humans; Iodoquinol; Metronidazole; Sex Factors; Sulfadiazine; Vulvovagin | 1969 |
[The problems of urogenital trichomonasis in prepuberal girls].
Topics: Adolescent; Child; Child, Preschool; Female; Humans; Infant; Metronidazole; Trichomonas Infections; | 1970 |
[Histological picture report No. 202. Vulvitis (vulvovaginitis) candidomycetica].
Topics: Adrenal Cortex Hormones; Adult; Antifungal Agents; Candidiasis, Vulvovaginal; Diabetes Complications | 1968 |
[The effect of new halogensulfonamides on vaginal microorganisms in women with trichomoniasis complicated by mycosis. Clinical part].
Topics: Candidiasis, Vulvovaginal; Female; Humans; Metronidazole; Mycoses; Sulfonamides; Vulvovaginitis | 1969 |
[Vulvitis and vaginitis].
Topics: Anti-Bacterial Agents; Candidiasis; Female; Humans; Metronidazole; Trichomonas Vaginitis; Vaginitis; | 1966 |