metronidazole has been researched along with Ventricular Fibrillation in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Acquired long QT syndrome is a rare condition whose diagnosis is of vital importance given the risk of torsade de pointes and sudden death." | 1.36 | [Perioperative acquired long QT syndrome: a case report]. ( Arizaga, A; Goitia, L; Pérez, P; Sebastián, P; Taibo, JM, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Goitia, L | 1 |
| Pérez, P | 1 |
| Sebastián, P | 1 |
| Taibo, JM | 1 |
| Arizaga, A | 1 |
| Paar, D | 1 |
| Terjung, B | 1 |
| Sauerbruch, T | 1 |
2 other studies available for metronidazole and Ventricular Fibrillation
| Article | Year |
|---|---|
[Perioperative acquired long QT syndrome: a case report].
Topics: Adjuvants, Anesthesia; Adrenergic beta-Antagonists; Amoxicillin-Potassium Clavulanate Combination; A | 2010 |
Life-threatening interaction between clarithromycin and disopyramide.
Topics: Aged; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Disopyramide | 1997 |