Page last updated: 2024-10-31

metronidazole and Venous Thrombosis

metronidazole has been researched along with Venous Thrombosis in 9 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Venous Thrombosis: The formation or presence of a blood clot (THROMBUS) within a vein.

Research Excerpts

ExcerptRelevanceReference
"Lemierre's syndrome is characterized by acute oropharyngeal infection complicated by internal jugular venous thrombosis secondary to septic thrombophlebitis, and metastatic abscesses."2.43Lemierre's syndrome presenting with peritonsillar abscess and VIth cranial nerve palsy. ( Jones, C; O'Reilly, BJ; Seymour, FK; Siva, TM, 2006)
"Lemierre syndrome is a disease that every pediatrician must know."1.35[Lemierre syndrome: a complication of an oropharyngeal infection]. ( Bailly, C; Berlioz, M; Boutté, P; Passalidou, P, 2008)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (55.56)29.6817
2010's4 (44.44)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pararajasingam, A1
Uwagwu, J1
Thati, V1
Nagral, S1
Yousaf, A1
Ahmed, M1
Aurangzeb, M1
Passalidou, P1
Berlioz, M1
Bailly, C1
Boutté, P1
Amezyane, T1
Abouzahir, A1
El Kharrass, A1
Bassou, D1
Fatihi, J1
Hammi, S1
Mahassin, F1
Ghafir, D1
Ohayon, V1
Valla, F1
Berchiche, C1
Floret, D1
Repanos, C1
Chadha, NK1
Griffiths, MV1
Jones, C1
Siva, TM1
Seymour, FK1
O'Reilly, BJ1
Habek, M1
Petravić, D1
Ozretić, D1
Brinar, VV1

Reviews

1 review available for metronidazole and Venous Thrombosis

ArticleYear
Lemierre's syndrome presenting with peritonsillar abscess and VIth cranial nerve palsy.
    The Journal of laryngology and otology, 2006, Volume: 120, Issue:6

    Topics: Abducens Nerve Diseases; Adolescent; Anti-Bacterial Agents; Cefotaxime; Female; Follow-Up Studies; H

2006

Other Studies

8 other studies available for metronidazole and Venous Thrombosis

ArticleYear
    BMJ case reports, 2017, Sep-13, Volume: 2017

    Topics: Aged; Anti-Bacterial Agents; Colony Count, Microbial; Drainage; Female; Fluconazole; Humans; Immunoc

2017
Inferior vena cava thrombus with pulmonary embolism complicating amebic liver abscess.
    Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology, 2014, Volume: 33, Issue:3

    Topics: Heparin, Low-Molecular-Weight; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; Pulm

2014
Acute Appendicitis Complicating into Portal and Superior Mesenteric Vein Thrombosis.
    Journal of the College of Physicians and Surgeons--Pakistan : JCPSP, 2016, Volume: 26, Issue:6 Suppl

    Topics: Acute Disease; Adult; Anti-Infective Agents; Anticoagulants; Appendicitis; Humans; Male; Mesenteric

2016
[Lemierre syndrome: a complication of an oropharyngeal infection].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2008, Volume: 15, Issue:12

    Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Cefotax

2008
[Septic pylephlebitis associated with Enterobacter cloacae septicemia].
    Journal des maladies vasculaires, 2010, Volume: 35, Issue:1

    Topics: Abdominal Pain; Adult; Anti-Bacterial Agents; Anticoagulants; Bacteremia; Ceftriaxone; Community-Acq

2010
[Necrobacillosis and Lemierre's syndrome: case report].
    Archives de pediatrie : organe officiel de la Societe francaise de pediatrie, 2003, Volume: 10, Issue:12

    Topics: Amoxicillin; Anti-Infective Agents; Brain Diseases; Child, Preschool; Female; Fusobacterium Infectio

2003
Sigmoid sinus thrombosis secondary to Lemierre's syndrome.
    Ear, nose, & throat journal, 2006, Volume: 85, Issue:2

    Topics: Adult; Anticoagulants; Cefuroxime; Drainage; Humans; Jugular Veins; Magnetic Resonance Imaging; Male

2006
Neurological picture. Horner syndrome due to jugular vein thrombosis (Lemierre syndrome).
    Journal of neurology, neurosurgery, and psychiatry, 2008, Volume: 79, Issue:3

    Topics: Anti-Infective Agents; Cefuroxime; Drug Therapy, Combination; Horner Syndrome; Humans; Jugular Veins

2008