metronidazole has been researched along with Uterine Neoplasms in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Uterine Neoplasms: Tumors or cancer of the UTERUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ultrasonographic findings suggested a molar pregnancy with two live fetuses." | 1.28 | Hydatidiform mole with coexisting twin pregnancy after gamete intra-fallopian transfer. ( Hemrika, DJ; Schutte, MF; ten Velden, JJ; van de Geijn, EJ; Yedema, CA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kiseleva, ES | 1 |
| Dar'ialova, SL | 1 |
| van de Geijn, EJ | 1 |
| Yedema, CA | 1 |
| Hemrika, DJ | 1 |
| Schutte, MF | 1 |
| ten Velden, JJ | 1 |
| Stoliarova, IV | 2 |
| Vinokurov, VL | 2 |
| Zharinov, GM | 2 |
| Val'kovich, AA | 2 |
| Saĭkin, VKh | 2 |
| Khanson, KP | 2 |
| Giamarellou, H | 1 |
| Okawa, T | 2 |
| Takahashi, S | 1 |
| Yokoyama, Y | 1 |
| Hongo, J | 1 |
| Matsuda, M | 1 |
| Yoneyama, S | 1 |
1 review available for metronidazole and Uterine Neoplasms
| Article | Year |
|---|---|
[Electron acceptor compounds as radiation sensitizers of hypoxic cells in human tumors].
Topics: Brain Neoplasms; Combined Modality Therapy; Esophageal Neoplasms; Female; Head and Neck Neoplasms; H | 1984 |
7 other studies available for metronidazole and Uterine Neoplasms
| Article | Year |
|---|---|
Hydatidiform mole with coexisting twin pregnancy after gamete intra-fallopian transfer.
Topics: Adult; Amoxicillin; Female; Gamete Intrafallopian Transfer; Humans; Hydatidiform Mole; Male; Metroni | 1992 |
[Clinical studies of radiation-sensitizing effects of metronidazole in patients with cancer of the uterine body].
Topics: Dimethyl Sulfoxide; Female; Humans; Metronidazole; Radiotherapy Dosage; Uterine Neoplasms; Uterus | 1991 |
[The local application of metronidazole during the radiotherapy of endometrial cancer].
Topics: Administration, Topical; Adult; Aged; Brachytherapy; Combined Modality Therapy; Dimethyl Sulfoxide; | 1990 |
Myonecrosis of the abdominal wall, complicating radical hysterectomy.
Topics: Abdominal Muscles; Amikacin; Bacillus; Cefotaxime; Clindamycin; Drug Therapy, Combination; Escherich | 1987 |
[Specific action of metronidazole on the bad odor emitted by uterine cancer].
Topics: Female; Humans; Infections; Metronidazole; Odorants; Radium; Uterine Neoplasms | 1969 |
[Elimination of offensive odors by using metronidazole-effect on tamponade during radium irradiation of uterine cancer].
Topics: Adult; Aged; Carcinoma, Squamous Cell; Female; Humans; Metronidazole; Middle Aged; Odorants; Radium; | 1968 |
[Findings on trichomonas vaginitis--from the view of uterine cancer examination].
Topics: Adult; Aged; Cytodiagnosis; Female; Humans; Metronidazole; Middle Aged; Trichomonas Vaginitis; Uteri | 1966 |