metronidazole has been researched along with Uterine Diseases in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Uterine Diseases: Pathological processes involving any part of the UTERUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ultrasonographic findings suggested a molar pregnancy with two live fetuses." | 1.28 | Hydatidiform mole with coexisting twin pregnancy after gamete intra-fallopian transfer. ( Hemrika, DJ; Schutte, MF; ten Velden, JJ; van de Geijn, EJ; Yedema, CA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 3 (37.50) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Larsson, PG | 1 |
| Carlsson, B | 1 |
| Hofmann, GE | 1 |
| Warikoo, P | 1 |
| Jacobs, W | 1 |
| Anand, S | 1 |
| Dieh, A | 1 |
| Mahmood, T | 1 |
| Vacca, A | 1 |
| Henderson, A | 1 |
| Csütörtöki, V | 1 |
| Stipkovits, L | 1 |
| Queck, M | 1 |
| Berle, P | 1 |
| van de Geijn, EJ | 1 |
| Yedema, CA | 1 |
| Hemrika, DJ | 1 |
| Schutte, MF | 1 |
| ten Velden, JJ | 1 |
| van den Bogaard, AE | 1 |
| Hazen, MJ | 1 |
| Kriele, CP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy of the Use of Metronidazole After Laparoscopic Hysterectomy for the Prevention of Vaginal Cellulitis or Vaginal Cuff Abscess. Multicentric Triple-blind Randomized Controlled Trial[NCT03917134] | 600 participants (Anticipated) | Interventional | 2019-05-01 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for metronidazole and Uterine Diseases
| Article | Year |
|---|---|
Does pre- and postoperative metronidazole treatment lower vaginal cuff infection rate after abdominal hysterectomy among women with bacterial vaginosis?
Topics: Administration, Rectal; Adult; Analysis of Variance; Antibiotic Prophylaxis; Female; Follow-Up Studi | 2002 |
[Local prevention of infection with metronidazole before vaginal hysterectomy--comparative effect compared with systemic prevention?].
Topics: Administration, Intravaginal; Cefuroxime; Female; Humans; Hysterectomy, Vaginal; Infusions, Intraven | 1992 |
6 other studies available for metronidazole and Uterine Diseases
| Article | Year |
|---|---|
Ultrasound detection of pyometra at the time of embryo transfer after ovum retrieval for in vitro fertilization.
Topics: Adult; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; | 2003 |
A large pelvic actinomycoma managed conservatively.
Topics: Actinomyces; Actinomycosis; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Di | 2008 |
Puerperal sepsis in Port Moresby, Papua New Guinea.
Topics: Bacteroides Infections; Chloramphenicol; Escherichia coli Infections; Female; Humans; Metronidazole; | 1980 |
[Detection of Mycoplasma pneumoniae infections in female sex organs].
Topics: Adult; Female; Genitalia, Female; Humans; Metronidazole; Mycoplasma; Mycoplasma Infections; Uterine | 1977 |
Hydatidiform mole with coexisting twin pregnancy after gamete intra-fallopian transfer.
Topics: Adult; Amoxicillin; Female; Gamete Intrafallopian Transfer; Humans; Hydatidiform Mole; Male; Metroni | 1992 |
Rationale for treatment of retained placenta in cows with neomycin and metronidazole.
Topics: Animals; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Cattle; Cattle Diseases; Drug | 1992 |