metronidazole has been researched along with Urinary Tract Diseases in 8 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| PEREYRA, AJ | 1 |
| LANSING, JD | 1 |
| Simon, J | 1 |
| Kiss, L | 1 |
| Kovács, A | 1 |
| Hegyi, J | 1 |
| Watson, RA | 1 |
| Summers, JL | 1 |
| Ford, ML | 1 |
| Breier, M | 1 |
| Turanova, EN | 1 |
| Potapnev, FV | 1 |
| Iatsukha, MV | 1 |
| Korik, LM | 1 |
| Elste, G | 1 |
1 review available for metronidazole and Urinary Tract Diseases
| Article | Year |
|---|---|
Gardnerella vaginalis: genitourinary pathogen in men.
Topics: Adult; Bacteriuria; Balanitis; Child; Culture Media; Cystitis; Female; Gardnerella vaginalis; Genita | 1985 |
1 trial available for metronidazole and Urinary Tract Diseases
| Article | Year |
|---|---|
Treatment of urogenital trichomoniasis with klion.
Topics: Clinical Trials as Topic; Female; Genital Diseases, Female; Genital Diseases, Male; Humans; Male; Me | 1972 |
6 other studies available for metronidazole and Urinary Tract Diseases
| Article | Year |
|---|---|
UROGENITAL TRICHOMONIASIS; TREATMENT WITH METRONIDAZOLE IN 2002 INCARCERATED WOMEN.
Topics: Coitus; Cross Infection; Epidemiology; Female; Humans; Metronidazole; Prognosis; Statistics as Topic | 1964 |
[Massive metronidazole (Klion) therapy of urogenital trichomonas infection].
Topics: Adolescent; Adult; Aged; Female; Genital Diseases, Male; Humans; Male; Metronidazole; Middle Aged; T | 1980 |
The Papanicolaou smear as a diagnostic tool in male trichomoniasis.
Topics: Cytodiagnosis; Genital Diseases, Male; Humans; Male; Methods; Metronidazole; Prostate; Prostatic Dis | 1972 |
[Comparative evaluation of the effectiveness of chlomisole, flagyl and trichopole in treating trichomoniasis in women].
Topics: Adolescent; Adult; Antitrichomonal Agents; Evaluation Studies as Topic; Female; Humans; Imidazoles; | 1971 |
[Effectiveness of specific immunotherapy in torpid forms of urogenital trichomoniasis].
Topics: Adult; Anti-Bacterial Agents; Complement Fixation Tests; Female; Humans; Immunotherapy; Male; Metron | 1971 |
[Trichomoniasis urogenitalis and metronidazol therapy in dermato-venerologic practice].
Topics: Adult; Female; Humans; Male; Metronidazole; Trichomonas Infections; Urinary Tract Infections; Urolog | 1966 |