metronidazole has been researched along with Urethral Diseases in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Urethral Diseases: Pathological processes involving the URETHRA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "He had urinary infection and severe ileocolitis." | 2.39 | Management of rectourethral fistulas in Crohn's disease. ( Bucci, L; Frizelle, FA; Santoro, GA, 1995) |
| "Recto-urethral fistulas due to Crohn's disease are very uncommon." | 1.35 | [Urethral fistula due to Crohn's disease: case report of successful conservative management]. ( Borovicka, J; Engeler, DS; Hetzer, FH; Meyer, D; Schmid, HP; Schwab, C, 2008) |
| "He had urinary infection and severe ileocolitis." | 1.30 | [Treatment of recto-urethral fistulas in Crohn's disease]. ( Aiello, C; Bucci, L; Cerbone, V; de Werra, C; Gentile, M; Santoro, GA, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Samaha, M | 1 |
| Moloney, M | 1 |
| Schwab, C | 1 |
| Meyer, D | 1 |
| Hetzer, FH | 1 |
| Borovicka, J | 1 |
| Schmid, HP | 1 |
| Engeler, DS | 1 |
| Santoro, GA | 2 |
| Bucci, L | 2 |
| Frizelle, FA | 1 |
| Aiello, C | 1 |
| Cerbone, V | 1 |
| de Werra, C | 1 |
| Gentile, M | 1 |
| Haarala, M | 1 |
| Kiilholma, P | 1 |
| Lehtonen, OP | 1 |
1 review available for metronidazole and Urethral Diseases
| Article | Year |
|---|---|
Management of rectourethral fistulas in Crohn's disease.
Topics: Adult; Crohn Disease; Follow-Up Studies; Humans; Male; Metronidazole; Perineum; Rectal Fistula; Scro | 1995 |
4 other studies available for metronidazole and Urethral Diseases
| Article | Year |
|---|---|
Long-term antibiotic therapy in late onset pouch-urethral fistula after ileoanal anastomosis for ulcerative colitis may be effective and well tolerated.
Topics: Adult; Anal Canal; Anastomosis, Surgical; Anti-Infective Agents; Ciprofloxacin; Colitis, Ulcerative; | 2013 |
[Urethral fistula due to Crohn's disease: case report of successful conservative management].
Topics: Azathioprine; Ciprofloxacin; Crohn Disease; Cystoscopy; Cystostomy; Diagnosis, Differential; Drug Th | 2008 |
[Treatment of recto-urethral fistulas in Crohn's disease].
Topics: Adult; Anti-Infective Agents; Crohn Disease; Follow-Up Studies; Humans; Immunosuppressive Agents; Ma | 1997 |
Urinary bacterial flora of women with urethral syndrome and interstitial cystitis.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Bacteria, Aerobic; Bacteria, Anaerobic; Bacteroides | 1999 |