metronidazole has been researched along with Ulcer in 18 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Ulcer: A lesion on the surface of the skin or a mucous surface, produced by the sloughing of inflammatory necrotic tissue.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 78-year-old patient with an ulcerous, purulent, exophytic fist-sized breast carcinoma (FIGO IVd) and a pulmonary metastasis who refused radiation, chemotherapy and operation, was treated with oral tamoxifen and metronidazole daily and with local antiseptics." | 7.69 | Influence of metronidazole and tamoxifen in a case of otherwise untreated ulcerous breast carcinoma. ( de la Motte, S; Heirler, F; Popp, W, 1995) |
| "A 78-year-old patient with an ulcerous, purulent, exophytic fist-sized breast carcinoma (FIGO IVd) and a pulmonary metastasis who refused radiation, chemotherapy and operation, was treated with oral tamoxifen and metronidazole daily and with local antiseptics." | 3.69 | Influence of metronidazole and tamoxifen in a case of otherwise untreated ulcerous breast carcinoma. ( de la Motte, S; Heirler, F; Popp, W, 1995) |
| "Emphysematous gastritis is a rare form of gastritis characterized by gaseous dissection of the stomach wall usually secondary to invasion by gas forming organisms, corrosive ingestion, trauma, or gastric infarction." | 1.37 | Emphysematous gastritis associated with ulcerative esophagitis. ( Abbass, K; Akram, S; Hassan, S; Markert, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (44.44) | 18.7374 |
| 1990's | 3 (16.67) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Vu, TB | 1 |
| Tran, TNQ | 1 |
| Tran, TQA | 1 |
| Vu, DL | 1 |
| Hoang, VT | 1 |
| Madhan, B | 1 |
| Arunprasad, G | 1 |
| Krishnan, B | 1 |
| Hassan, S | 1 |
| Abbass, K | 1 |
| Markert, R | 1 |
| Akram, S | 1 |
| Alcalde-Vargas, A | 1 |
| Trigo-Salado, C | 1 |
| Leo Carnerero, E | 1 |
| De-la-Cruz-Ramírez, D | 1 |
| Herrera-Justiniano, JM | 1 |
| Magaña, M | 1 |
| Magaña, ML | 1 |
| Alcántara, A | 1 |
| Pérez-Martín, MA | 1 |
| Lemoine, M | 1 |
| Dray, X | 1 |
| Lavergne-Slove, A | 1 |
| Vahedi, K | 1 |
| Ashford, R | 1 |
| Plant, G | 1 |
| Maher, J | 1 |
| Teare, L | 1 |
| Carmichael, DH | 1 |
| Schulte, MJ | 1 |
| Heirler, F | 1 |
| de la Motte, S | 1 |
| Popp, W | 1 |
| Dechant, JE | 1 |
| MacDonald, DG | 1 |
| Crawford, WH | 1 |
| O'Connor, BP | 1 |
| Sugarman, JL | 1 |
| Mauro, TM | 1 |
| Frieden, IJ | 1 |
| Jones, PH | 1 |
| Willis, AT | 1 |
| Ferguson, IR | 1 |
| Davidson, F | 1 |
| Gnaanachelvan, K | 1 |
| Marsden, RA | 1 |
| Cooke, M | 1 |
| Brusis, T | 1 |
| Luckhaupt, H | 1 |
| Khanna, AK | 1 |
| Khanna, A | 1 |
| Asthana, AK | 1 |
| Powell, SJ | 1 |
| Wilmot, AJ | 1 |
| Elsdon-Dew, R | 1 |
| Leegaard, OF | 1 |
1 trial available for metronidazole and Ulcer
| Article | Year |
|---|---|
Double-blind trial of metronidazole in malodorous ulcerating tumours.
Topics: Clinical Trials as Topic; Double-Blind Method; Humans; Metronidazole; Neoplasms; Random Allocation; | 1984 |
17 other studies available for metronidazole and Ulcer
| Article | Year |
|---|---|
Antibiotic Resistance of
Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Cross-Sectional Studies; Drug | 2022 |
Paraquat tongue.
Topics: Adult; Anesthetics, Local; Anti-Infective Agents; Benzocaine; Gels; Herbicides; Humans; Male; Metron | 2014 |
Emphysematous gastritis associated with ulcerative esophagitis.
Topics: Aged; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Diabetes Mellitus, Type 2; Emphyse | 2011 |
Pseudomembranous colitis and bacteremia in an immune competent patient associated with a rare specie of Clostridium (C. ramosum).
Topics: Aged; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Bacteremia; Ciprofloxaci | 2012 |
Histopathology of cutaneous amebiasis.
Topics: Adult; Amebiasis; Animals; Anti-Infective Agents; Antiparasitic Agents; Emetine; Entamoeba histolyti | 2004 |
A man with periappendicular ulcerations.
Topics: Adult; Antiprotozoal Agents; Appendix; Cecum; Dysentery, Amebic; Entamoebiasis; Humans; Hydroxyquino | 2005 |
The draining malignant ulceration.
Topics: Humans; Metronidazole; Neoplasms; Odorants; Ulcer | 1981 |
Yogurt helps to control wound odor.
Topics: Administration, Topical; Combined Modality Therapy; Humans; Metronidazole; Mycoses; Odorants; Thorac | 1993 |
Influence of metronidazole and tamoxifen in a case of otherwise untreated ulcerous breast carcinoma.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Female; Humans; Metronidazol | 1995 |
Pleuritis associated with perforation of an isolated oesophageal ulcer in a horse.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents, Non-Steroidal; Clinical Chemistry Tests; C | 1998 |
Treatment of an ulcerated hemangioma with recombinant platelet-derived growth factor.
Topics: Administration, Topical; Anti-Infective Agents; Becaplermin; Drug Therapy, Combination; Female; Gels | 2002 |
Treatment of anaerobically infected pressure sores with topical metronidazole.
Topics: Administration, Topical; Aged; Bacterial Infections; Humans; Metronidazole; Pressure Ulcer; Ulcer | 1978 |
Deep and acute vulval ulceration. Case report.
Topics: Adult; Anti-Infective Agents, Urinary; Drug Therapy, Combination; Female; Humans; Metronidazole; Tri | 1989 |
Fetor from ulcerated head and neck tumors: causation and therapy.
Topics: Bacteria, Anaerobic; Bacterial Infections; Clindamycin; Humans; Larynx; Metronidazole; Mouth; Odoran | 1989 |
Postirradiation ulcer and topical metronidazole.
Topics: Breast Neoplasms; Carcinoma, Squamous Cell; Female; Humans; Metronidazole; Middle Aged; Radiation In | 1988 |
Single and low dosage regimens of metronidazole in amoebic dysentery and amoebic liver abscess.
Topics: Acute Disease; Adult; Dysentery, Amebic; Entamoeba histolytica; Humans; Liver Abscess, Amebic; Male; | 1969 |
[Giardiasis. A review and report of a case of imported diarrhea and infection with Giardia intestinalis].
Topics: Adult; Diagnosis, Differential; Diarrhea; Giardiasis; Humans; Intestinal Absorption; Malabsorption S | 1971 |