metronidazole has been researched along with Trichuriasis in 9 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Trichuriasis: Infection with nematodes of the genus TRICHURIS, formerly called Trichocephalus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report a case of massive Trichuris trichiura infection, resulting in severe anaemia and congestive cardiac failure in a 9-year-old Iban boy, who was resistant to the usual oral anthelmintic treatment, but promptly responded to mebendazole retention enema." | 3.67 | Mebendazole retention enema for severe Trichuris trichiura (whipworm) infection: a case report. ( Bhattacharya, S; Ray, S; Sebastian, VJ, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kopper, JJ | 1 |
| Patterson, JS | 1 |
| Mansfield, LS | 1 |
| Cortizo-Vidal, S | 1 |
| Rodríguez-Otero, LM | 1 |
| Villamil-Cajoto, I | 1 |
| Llovo-Taboada, J | 1 |
| Zrubec, J | 1 |
| Botero, D | 1 |
| Garcia-Laverde, A | 1 |
| de Bonilla, L | 1 |
| Köksal, I | 1 |
| Malkoç, CH | 1 |
| Ozergin, O | 1 |
| Düğdü, S | 1 |
| Ozgürbüz, F | 1 |
| Cakmak, T | 1 |
| Beşer, E | 1 |
| Sebastian, VJ | 1 |
| Bhattacharya, S | 1 |
| Ray, S | 1 |
| Lelong, M | 1 |
| Deroubaix, P | 1 |
| Derambure, S | 1 |
| Sorez, JP | 1 |
| Vanlaeys, R | 1 |
| Thelliez, P | 1 |
| Hogedez, G | 1 |
| Schreiber, W | 1 |
1 review available for metronidazole and Trichuriasis
| Article | Year |
|---|---|
Chemotherapy of human intestinal parasitic diseases.
Topics: Amebiasis; Amides; Ancylostomiasis; Ascariasis; Bephenium Compounds; Cestode Infections; Emetine; Fu | 1978 |
1 trial available for metronidazole and Trichuriasis
| Article | Year |
|---|---|
Clinical trials with metronidazole in human balantidiasis.
Topics: Adolescent; Adult; Animals; Balantidiasis; Balantidium; Child; Child, Preschool; Dose-Response Relat | 1975 |
7 other studies available for metronidazole and Trichuriasis
| Article | Year |
|---|---|
Metronidazole-but not IL-10 or prednisolone-rescues Trichuris muris infected C57BL/6 IL-10 deficient mice from severe disease.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Female; Gene Expression Regulation; Inflam | 2015 |
[Eosinophilia in an adopted native Ethiopian girl].
Topics: Adoption; Amebiasis; Animals; Anthelmintics; Antiprotozoal Agents; Blastocystis hominis; Blastocysti | 2010 |
[Balantidiasis in children and its treatment with metrodiazole].
Topics: Balantidiasis; Child; Female; Humans; Male; Metronidazole; Trichuriasis | 1967 |
[The prevalence of intestinal parasites in primary school students in Trabzon and the importance of education of parasite patients].
Topics: Ascariasis; Child; Feces; Giardiasis; Health Education; Humans; Intestinal Diseases, Parasitic; Mebe | 1992 |
Mebendazole retention enema for severe Trichuris trichiura (whipworm) infection: a case report.
Topics: Anemia; Brunei; Child; Enema; Entamoebiasis; Heart Failure; Humans; Male; Mebendazole; Metronidazole | 1989 |
[Intestinal parasitoses in a general hospital pediatric department of (statistics for 12 years)].
Topics: Adolescent; Age Factors; Ascariasis; Child; Child, Preschool; Female; France; Giardiasis; Humans; In | 1973 |
[Parasitoses of the intestinal tract].
Topics: Bephenium Compounds; Diagnosis, Differential; Eosinophilia; Giardiasis; Humans; Intestinal Diseases, | 1974 |