metronidazole has been researched along with Toxoplasmosis, Animal in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Toxoplasmosis, Animal: Acquired infection of non-human animals by organisms of the genus TOXOPLASMA.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hegazy, MM | 1 |
| Elmehankar, MS | 1 |
| Azab, MS | 1 |
| El-Tantawy, NL | 1 |
| Abdel-Aziz, A | 1 |
| Hagras, NA | 1 |
| Allam, AF | 1 |
| Farag, HF | 1 |
| Osman, MM | 1 |
| Shalaby, TI | 1 |
| Fawzy Hussein Mogahed, NM | 1 |
| Tolba, MM | 1 |
| Shehab, AY | 1 |
2 other studies available for metronidazole and Toxoplasmosis, Animal
| Article | Year |
|---|---|
Sex dichotomy in the course of experimental latent toxoplasmosis.
Topics: Animals; Antibodies, Protozoan; Atovaquone; Brain; Chronic Disease; Coccidiostats; Drug Therapy, Com | 2019 |
Successful treatment of acute experimental toxoplasmosis by spiramycin-loaded chitosan nanoparticles.
Topics: Acute Disease; Animals; Ascitic Fluid; Biocompatible Materials; Blood-Brain Barrier; Brain; Chitosan | 2019 |