metronidazole has been researched along with Tooth Discoloration in 11 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Tooth Discoloration: Any change in the hue, color, or translucency of a tooth due to any cause. Restorative filling materials, drugs (both topical and systemic), pulpal necrosis, or hemorrhage may be responsible. (Jablonski, Dictionary of Dentistry, 1992, p253)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among the components of the triple antibiotic paste, only minocycline caused the tooth discoloration." | 5.14 | Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report. ( Jung, IY; Kim, JH; Kim, Y; Park, JW; Shin, SJ, 2010) |
| " The knowledge of adverse effects of antibiotics was greatest for tooth discoloration which is related to tetracycline." | 3.80 | Antibiotics prescription in Nigerian dental healthcare services. ( Azodo, CC; Ojehanon, PI, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 10 (90.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Iriboz, E | 1 |
| Öztürk, BA | 1 |
| Körklü, S | 1 |
| Tarcin, B | 1 |
| Berker, YG | 1 |
| Öveçoğlu, HS | 1 |
| Fundaoğlu Küçükekenci, F | 1 |
| Çakici, F | 1 |
| Küçükekenci, AS | 1 |
| Mendes, LO | 1 |
| Machado, NE | 1 |
| Goldoni, PR | 1 |
| Mori, GG | 1 |
| AlSaeed, T | 1 |
| Nosrat, A | 1 |
| Melo, MA | 1 |
| Wang, P | 1 |
| Romberg, E | 1 |
| Xu, H | 1 |
| Fouad, AF | 1 |
| Nagata, JY | 1 |
| Gomes, BP | 1 |
| Rocha Lima, TF | 1 |
| Murakami, LS | 1 |
| de Faria, DE | 1 |
| Campos, GR | 1 |
| de Souza-Filho, FJ | 1 |
| Soares, Ade J | 1 |
| Akcay, M | 1 |
| Arslan, H | 1 |
| Yasa, B | 1 |
| Kavrık, F | 1 |
| Yasa, E | 1 |
| Kirchhoff, AL | 1 |
| Raldi, DP | 1 |
| Salles, AC | 1 |
| Cunha, RS | 1 |
| Mello, I | 1 |
| Azodo, CC | 1 |
| Ojehanon, PI | 1 |
| Zaugg, LK | 1 |
| Lenherr, P | 1 |
| Zaugg, JB | 1 |
| Weiger, R | 1 |
| Krastl, G | 1 |
| Reynolds, K | 1 |
| Johnson, JD | 1 |
| Cohenca, N | 1 |
| Kim, JH | 1 |
| Kim, Y | 1 |
| Shin, SJ | 1 |
| Park, JW | 1 |
| Jung, IY | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Research of the Application of Triple Antibiotic Paste in Primary Teeth With[NCT02196740] | 100 participants (Anticipated) | Interventional | 2013-06-30 | Active, not recruiting | |||
| Clinical and Microbiological Evaluation of a Series of Clinical Cases of Permanent Teeth With Incomplete Apexogenesis and Traumatic Necrosis, Treated With Double Antimicrobial Paste, Revascularization Procedures, and MTA[NCT03112291] | 14 participants (Actual) | Interventional | 2011-11-25 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for metronidazole and Tooth Discoloration
| Article | Year |
|---|---|
Traumatized immature teeth treated with 2 protocols of pulp revascularization.
Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents, Local; Apexification; Calcium Hydroxide; C | 2014 |
Traumatized immature teeth treated with 2 protocols of pulp revascularization.
Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents, Local; Apexification; Calcium Hydroxide; C | 2014 |
Traumatized immature teeth treated with 2 protocols of pulp revascularization.
Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents, Local; Apexification; Calcium Hydroxide; C | 2014 |
Traumatized immature teeth treated with 2 protocols of pulp revascularization.
Topics: Adolescent; Anti-Bacterial Agents; Anti-Infective Agents, Local; Apexification; Calcium Hydroxide; C | 2014 |
Tooth discoloration of immature permanent incisor associated with triple antibiotic therapy: a case report.
Topics: Acrylic Resins; Anti-Bacterial Agents; Anti-Infective Agents; Child; Ciprofloxacin; Colorimetry; Den | 2010 |
9 other studies available for metronidazole and Tooth Discoloration
| Article | Year |
|---|---|
Comparison of intracoronal bleaching methods on teeth discolored by different antibiotic pastes.
Topics: Anti-Bacterial Agents; Bleaching Agents; Borates; Ciprofloxacin; Dental Pulp Cavity; Drug Combinatio | 2017 |
Spectrophotometric analysis of discoloration and internal bleaching after use of different antibiotic pastes.
Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Ciprofloxacin; Doxycycline; Humans; Hydrogen Peroxide; | 2019 |
Evaluation of tooth discoloration after the use of experimental medication as root canal dressings: an in vitro study.
Topics: Animals; Cattle; Chlorhexidine; Color; Doxycycline; Drug Evaluation, Preclinical; In Vitro Technique | 2018 |
Antibacterial Efficacy and Discoloration Potential of Endodontic Topical Antibiotics.
Topics: Administration, Topical; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Cipro | 2018 |
Spectrophotometric analysis of crown discoloration induced by various antibiotic pastes used in revascularization.
Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Calcium Hydroxide; Cattle; Cefaclor; Ciprofloxacin; Col | 2014 |
Tooth discolouration and internal bleaching after the use of triple antibiotic paste.
Topics: Anti-Bacterial Agents; Bicuspid; Borates; Ciprofloxacin; Drug Combinations; Humans; In Vitro Techniq | 2015 |
Antibiotics prescription in Nigerian dental healthcare services.
Topics: Acquired Immunodeficiency Syndrome; Amoxicillin; Anaphylaxis; Anti-Bacterial Agents; Antibiotic Prop | 2014 |
Influence of the bleaching interval on the luminosity of long-term discolored enamel-dentin discs.
Topics: Aluminum Compounds; Animals; Borates; Calcium Compounds; Cattle; Ciprofloxacin; Demeclocycline; Dent | 2016 |
Pulp revascularization of necrotic bilateral bicuspids using a modified novel technique to eliminate potential coronal discolouration: a case report.
Topics: Anti-Bacterial Agents; Anti-Infective Agents; Bicuspid; Child; Ciprofloxacin; Dental Fistula; Dental | 2009 |