metronidazole has been researched along with Tinnitus in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Tinnitus: A nonspecific symptom of hearing disorder characterized by the sensation of buzzing, ringing, clicking, pulsations, and other noises in the ear. Objective tinnitus refers to noises generated from within the ear or adjacent structures that can be heard by other individuals. The term subjective tinnitus is used when the sound is audible only to the affected individual. Tinnitus may occur as a manifestation of COCHLEAR DISEASES; VESTIBULOCOCHLEAR NERVE DISEASES; INTRACRANIAL HYPERTENSION; CRANIOCEREBRAL TRAUMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "As a healthcare profession, dentists have a role in ensuring the safety of prescribed medicines by reporting adverse drug reactions using the Yellow Card Scheme." | 6.53 | Metronidazole and tinnitus: A potential side effect? ( Barker, D; O'Donnell, KL, 2016) |
| "As a healthcare profession, dentists have a role in ensuring the safety of prescribed medicines by reporting adverse drug reactions using the Yellow Card Scheme." | 2.53 | Metronidazole and tinnitus: A potential side effect? ( Barker, D; O'Donnell, KL, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| O'Donnell, KL | 1 |
| Barker, D | 1 |
| Iqbal, SM | 1 |
| Murthy, JG | 1 |
| Banerjee, PK | 1 |
| Vishwanathan, KA | 1 |
1 review available for metronidazole and Tinnitus
| Article | Year |
|---|---|
Metronidazole and tinnitus: A potential side effect?
Topics: Anti-Infective Agents; Female; Focal Infection, Dental; Gingivitis; Humans; Metronidazole; Middle Ag | 2016 |
1 other study available for metronidazole and Tinnitus
| Article | Year |
|---|---|
Metronidazole ototoxicity--report of two cases.
Topics: Adolescent; Adult; Anti-Infective Agents; Audiometry, Pure-Tone; Female; Glucocorticoids; Hearing Lo | 1999 |