metronidazole has been researched along with Thrombosis in 13 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Thrombosis: Formation and development of a thrombus or blood clot in the blood vessel.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Indices of platelet function, plasmic coagulation and fibrinolysis were studied during gamma-beam therapy in patients with laryngeal, gastric and cervical tumors (potentially at risk for thrombosis) against a background of metronidazole administration." | 3.67 | [Hemostasis in cancer patients during radiation therapy using metronidazole]. ( Andreev, VG; Berdov, BA; Chekalina, SI; Pavlov, VV, 1989) |
| "Histologic examination confirmed Crohn's disease that was associated with vasculitis and, in particular, with thrombophlebitis and subsequent transmural bowel necrosis." | 1.32 | [Pylephlebitis with air in the portal vein system. An unusual focus in a patient with sepsis]. ( Gocht, A; Hahn, KE; Kluge, S; Kreymann, G; Lund, CH, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (15.38) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 6 (46.15) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Alagl, A | 1 |
| Bedi, S | 1 |
| Hassan, K | 1 |
| AlHumaid, J | 1 |
| Martin, L | 1 |
| Burute, N | 1 |
| Haider, E | 1 |
| Serrano, PE | 1 |
| O'Shea, T | 1 |
| Siegal, D | 1 |
| Teh, BM | 1 |
| Gordon, R | 1 |
| Rowe, D | 1 |
| Fuller, A | 1 |
| Jeyarajan, H | 1 |
| Neelamurthy, PS | 1 |
| Kumar, RA | 1 |
| Balakrishnan, V | 1 |
| Venkatesan, SM | 1 |
| Narayan, GS | 1 |
| I, K | 1 |
| Kopper, JJ | 1 |
| Patterson, JS | 1 |
| Mansfield, LS | 1 |
| Aebischer, B | 1 |
| Elsig, S | 1 |
| Taeymans, J | 1 |
| Pomp, S | 1 |
| Kuhness, D | 1 |
| Barcaro, G | 1 |
| Sementa, L | 1 |
| Mankad, V | 1 |
| Fortunelli, A | 1 |
| Sterrer, M | 1 |
| Netzer, FP | 1 |
| Surnev, S | 1 |
| Schmieder, AH | 1 |
| Caruthers, SD | 1 |
| Keupp, J | 1 |
| Wickline, SA | 1 |
| Lanza, GM | 1 |
| Lowe, J | 1 |
| Wodarcyk, AJ | 1 |
| Floyd, KT | 1 |
| Rastogi, N | 1 |
| Schultz, EJ | 1 |
| Swager, SA | 1 |
| Chadwick, JA | 1 |
| Tran, T | 1 |
| Raman, SV | 1 |
| Janssen, PM | 1 |
| Rafael-Fortney, JA | 1 |
| Alcalay, RN | 1 |
| Levy, OA | 1 |
| Wolf, P | 1 |
| Oliva, P | 1 |
| Zhang, XK | 1 |
| Waters, CH | 1 |
| Fahn, S | 1 |
| Kang, U | 1 |
| Liong, C | 1 |
| Ford, B | 1 |
| Mazzoni, P | 1 |
| Kuo, S | 1 |
| Johnson, A | 1 |
| Xiong, L | 1 |
| Rouleau, GA | 1 |
| Chung, W | 1 |
| Marder, KS | 1 |
| Gan-Or, Z | 1 |
| Kamei, K | 1 |
| Terao, T | 1 |
| Katayama, Y | 1 |
| Hatano, K | 1 |
| Kodama, K | 1 |
| Shirahama, M | 1 |
| Sakai, A | 1 |
| Hirakawa, H | 1 |
| Mizokami, Y | 1 |
| Shiotsuki, I | 1 |
| Ishii, N | 1 |
| Inoue, Y | 1 |
| Akboga, MK | 1 |
| Yayla, C | 1 |
| Balci, KG | 1 |
| Ozeke, O | 1 |
| Maden, O | 1 |
| Kisacik, H | 1 |
| Temizhan, A | 1 |
| Aydogdu, S | 1 |
| Zhu, J | 2 |
| Ying, SH | 1 |
| Feng, MG | 1 |
| Zhang, XG | 1 |
| Li, H | 1 |
| Wang, L | 1 |
| Hao, YY | 1 |
| Liang, GD | 1 |
| Ma, YH | 1 |
| Yang, GS | 1 |
| Hu, JH | 1 |
| Pfeifer, L | 1 |
| Goertz, RS | 1 |
| Neurath, MF | 1 |
| Strobel, D | 1 |
| Wildner, D | 1 |
| Lin, JT | 1 |
| Yang, XN | 1 |
| Zhong, WZ | 1 |
| Liao, RQ | 1 |
| Dong, S | 1 |
| Nie, Q | 1 |
| Weng, SX | 1 |
| Fang, XJ | 1 |
| Zheng, JY | 1 |
| Wu, YL | 1 |
| Řezanka, T | 1 |
| Kaineder, K | 1 |
| Mezricky, D | 1 |
| Řezanka, M | 1 |
| Bišová, K | 1 |
| Zachleder, V | 1 |
| Vítová, M | 1 |
| Rinker, JA | 1 |
| Marshall, SA | 1 |
| Mazzone, CM | 1 |
| Lowery-Gionta, EG | 1 |
| Gulati, V | 1 |
| Pleil, KE | 1 |
| Kash, TL | 1 |
| Navarro, M | 1 |
| Thiele, TE | 1 |
| Zhang, Y | 1 |
| Huang, Y | 1 |
| Jin, Z | 1 |
| Li, X | 1 |
| Li, B | 1 |
| Xu, P | 1 |
| Huang, P | 1 |
| Liu, C | 1 |
| Fokdal, L | 1 |
| Sturdza, A | 1 |
| Mazeron, R | 1 |
| Haie-Meder, C | 1 |
| Tan, LT | 1 |
| Gillham, C | 1 |
| Šegedin, B | 1 |
| Jürgenliemk-Schultz, I | 1 |
| Kirisits, C | 1 |
| Hoskin, P | 1 |
| Pötter, R | 1 |
| Lindegaard, JC | 1 |
| Tanderup, K | 1 |
| Levin, DE | 1 |
| Schmitz, AJ | 1 |
| Hines, SM | 1 |
| Hines, KJ | 1 |
| Tucker, MJ | 1 |
| Brewer, SH | 1 |
| Fenlon, EE | 1 |
| Álvarez-Pérez, S | 1 |
| Blanco, JL | 1 |
| Peláez, T | 1 |
| Martínez-Nevado, E | 1 |
| García, ME | 1 |
| Puckerin, AA | 1 |
| Chang, DD | 1 |
| Subramanyam, P | 1 |
| Colecraft, HM | 1 |
| Dogan, H | 1 |
| Coteli, E | 1 |
| Karatas, F | 1 |
| Ceylan, O | 1 |
| Sahin, MD | 1 |
| Akdamar, G | 1 |
| Kryczyk, A | 1 |
| Żmudzki, P | 1 |
| Hubicka, U | 1 |
| Giovannelli, D | 1 |
| Chung, M | 1 |
| Staley, J | 1 |
| Starovoytov, V | 1 |
| Le Bris, N | 1 |
| Vetriani, C | 1 |
| Chen, W | 1 |
| Wu, L | 1 |
| Liu, X | 1 |
| Shen, Y | 1 |
| Liang, Y | 1 |
| Tan, H | 1 |
| Yang, Y | 1 |
| Liu, Q | 1 |
| Wang, M | 1 |
| Liu, L | 1 |
| Wang, X | 1 |
| Liu, B | 1 |
| Liu, GH | 1 |
| Zhu, YJ | 1 |
| Wang, JP | 1 |
| Che, JM | 1 |
| Chen, QQ | 1 |
| Chen, Z | 1 |
| Maucksch, U | 1 |
| Runge, R | 1 |
| Wunderlich, G | 1 |
| Freudenberg, R | 1 |
| Naumann, A | 1 |
| Kotzerke, J | 1 |
| Kluge, S | 1 |
| Hahn, KE | 1 |
| Lund, CH | 1 |
| Gocht, A | 1 |
| Kreymann, G | 1 |
| Bredow, V | 1 |
| Schmeisser, JO | 1 |
| Sill, U | 1 |
| Thomas, H | 1 |
| Kruse, R | 1 |
| Schwesinger, G | 1 |
| Wernekinck, C | 1 |
| Dahmane, N | 1 |
| Persson, A | 1 |
| Thomassen, P | 1 |
| Bouton, F | 1 |
| Cotils, M | 1 |
| Genard, M | 1 |
| Hubert, C | 1 |
| Chowdhury, PS | 1 |
| Timmis, SB | 1 |
| Marcovitz, PA | 1 |
| Chekalina, SI | 1 |
| Berdov, BA | 1 |
| Pavlov, VV | 1 |
| Andreev, VG | 1 |
| Taylor, JA | 1 |
2 reviews available for metronidazole and Thrombosis
| Article | Year |
|---|---|
Topics: AC133 Antigen; Acenaphthenes; Acer; Acrosome Reaction; Adult; Agaricales; Aged; Aged, 80 and over; A | 2016 |
[Septic thrombophlebitis of the internal jugular vein and Lemierre syndrome].
Topics: Abscess; Acute Disease; Aged; Amoxicillin-Potassium Clavulanate Combination; Angina Pectoris; Anti-B | 1998 |
1 trial available for metronidazole and Thrombosis
| Article | Year |
|---|---|
Pharmacodynamic observations on metronidazole therapy. Side effects in endocrine, metabolic and auto-immune disorders. 3. Anti-ischemic and anti-inflammatory action in peripheral vascular disorders.
Topics: Blood Circulation; Blood Flow Velocity; Blood Pressure; Clinical Trials as Topic; Diabetes Complicat | 1966 |
10 other studies available for metronidazole and Thrombosis
| Article | Year |
|---|---|
Use of platelet-rich plasma for regeneration in non-vital immature permanent teeth: Clinical and cone-beam computed tomography evaluation.
Topics: Aluminum Compounds; Anti-Bacterial Agents; Bone Density; Calcium Compounds; Cefaclor; Child; Ciprofl | 2017 |
Occult Amebic Liver Abscess as Cause of Extensive Inferior Vena Cava and Hepatic Vein Thrombosis.
Topics: Adult; Antiprotozoal Agents; Hepatic Veins; Humans; Liver Abscess, Amebic; Male; Metronidazole; Paro | 2017 |
Intravascular abscess in Lemierre's syndrome due to meticillin-sensitive Staphylococcus aureus.
Topics: Abscess; Adult; Anti-Bacterial Agents; Cefazolin; Clindamycin; Humans; Jugular Veins; Lemierre Syndr | 2018 |
Revascularization in Immature and Mature Teeth with Necrotic Pulp: A Clinical Study.
Topics: Adolescent; Adult; Aluminum Compounds; Anti-Bacterial Agents; Calcium Compounds; Child; Ciprofloxaci | 2018 |
Metronidazole-but not IL-10 or prednisolone-rescues Trichuris muris infected C57BL/6 IL-10 deficient mice from severe disease.
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Female; Gene Expression Regulation; Inflam | 2015 |
[Pylephlebitis with air in the portal vein system. An unusual focus in a patient with sepsis].
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents; Anticoagulants; Cefotaxime; Crohn Disease; Diag | 2003 |
[Puerperal ovarian vein thrombosis in a 14-year-old patient after cesarean section for twin pregnancy].
Topics: Adolescent; Cefotiam; Cesarean Section; Combined Modality Therapy; Drug Therapy, Combination; Female | 1996 |
Ovarian vein thrombosis with symptoms prior to term--a case report.
Topics: Adult; Anticoagulants; Bacteroides; Bacteroides Infections; C-Reactive Protein; Diagnosis, Different | 1997 |
Clostridium perfringens within intracardiac thrombus: a case of intracardiac gas gangrene.
Topics: Aged; Anti-Bacterial Agents; Cardiomyopathy, Dilated; Clostridium perfringens; Echocardiography, Tra | 1999 |
[Hemostasis in cancer patients during radiation therapy using metronidazole].
Topics: Combined Modality Therapy; Female; Hemostasis; Humans; Laryngeal Neoplasms; Metronidazole; Preoperat | 1989 |