Page last updated: 2024-10-31

metronidazole and Thromboembolism

metronidazole has been researched along with Thromboembolism in 2 studies

Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.

Thromboembolism: Obstruction of a blood vessel (embolism) by a blood clot (THROMBUS) in the blood stream.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Powers, A1
Loesch, EB1
Weiland, A1
Fioravanti, N1
Lucius, D1
Cheung, WY1
Bellas, J1

Other Studies

2 other studies available for metronidazole and Thromboembolism

ArticleYear
Preemptive warfarin dose reduction after initiation of sulfamethoxazole-trimethoprim or metronidazole.
    Journal of thrombosis and thrombolysis, 2017, Volume: 44, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Female; Hemorrhage; Humans; International Normalized Ratio; Male; Me

2017
Fusobacterium: elusive cause of life-threatening septic thromboembolism.
    Canadian family physician Medecin de famille canadien, 2007, Volume: 53, Issue:9

    Topics: Adult; Anti-Infective Agents; Anticoagulants; Fusobacterium; Fusobacterium Infections; Humans; Liver

2007