metronidazole has been researched along with Thoracic Diseases in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Thoracic Diseases: Disorders affecting the organs of the thorax.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mainstay of the treatment of actinomycosis remains to be a combination of abscess drainage as well as prolonged antibiotics such as penicillin." | 1.35 | Thoracic actinomycosis in an adolescent mimicking chest wall tumor or pulmonary tuberculosis. ( Chao, NS; Kwok, WK; Leung, MW; Wong, QH; Yeung, VH, 2008) |
| "Thoracic actinomycosis is a rare infection but sensitive to penicillin G which is the antibiotic of choice." | 1.29 | [Diffuse nodular dissemination of thoracic actinomycosis]. ( Chaouat, A; Grunenberger, S; Ifoundza, TP; Kessler, R; Weitzenblum, E, 1994) |
| "Of 33 patients with amoebic liver abscess (ALA) seen over a 5-year period, 24 had intrathoracic complications." | 1.27 | Intrathoracic complications of amoebic liver abscess. ( Aderounmu, A; Adeyemo, AO, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yeung, VH | 1 |
| Wong, QH | 1 |
| Chao, NS | 1 |
| Leung, MW | 1 |
| Kwok, WK | 1 |
| Adeyemo, AO | 1 |
| Aderounmu, A | 1 |
| Ibarra-Pérez, C | 1 |
| Kessler, R | 1 |
| Ifoundza, TP | 1 |
| Chaouat, A | 1 |
| Grunenberger, S | 1 |
| Weitzenblum, E | 1 |
| Schulte, MJ | 1 |
| Coulibaly, G | 1 |
| Touraine, F | 1 |
| Clavel, M | 1 |
| Denis, F | 1 |
| Melloni, B | 1 |
| Bonnaud, F | 1 |
6 other studies available for metronidazole and Thoracic Diseases
| Article | Year |
|---|---|
Thoracic actinomycosis in an adolescent mimicking chest wall tumor or pulmonary tuberculosis.
Topics: Abscess; Actinomycosis; Anti-Infective Agents; Child; Combined Modality Therapy; Diagnosis, Differen | 2008 |
Intrathoracic complications of amoebic liver abscess.
Topics: Adolescent; Adult; Central Nervous System Diseases; Child; Drainage; Empyema; Female; Fistula; Human | 1984 |
Thoracic complications of amebic abscess of the liver: report of 501 cases.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drainage; Emetine; Humans; Liver Abscess, Amebic; | 1981 |
[Diffuse nodular dissemination of thoracic actinomycosis].
Topics: Actinomycosis; Adult; Drug Therapy, Combination; Fusidic Acid; Humans; Male; Metronidazole; Radiogra | 1994 |
Yogurt helps to control wound odor.
Topics: Administration, Topical; Combined Modality Therapy; Humans; Metronidazole; Mycoses; Odorants; Thorac | 1993 |
[Pulmonary infection caused by Fusobacterium nucleatum].
Topics: Anti-Bacterial Agents; Drainage; Follow-Up Studies; Fusobacterium Infections; Fusobacterium nucleatu | 1997 |