metronidazole has been researched along with Teeth, Devitalized in 9 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 9 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Scarparo, RK | 3 |
| Dondoni, L | 3 |
| Böttcher, DE | 3 |
| Grecca, FS | 3 |
| Figueiredo, JA | 2 |
| Kantarci, A | 1 |
| Van Dyke, TE | 1 |
| Batista, EL | 3 |
| Ray, HL | 1 |
| Marcelino, J | 1 |
| Braga, R | 1 |
| Horwat, R | 1 |
| Lisien, M | 1 |
| Khaliq, S | 1 |
| Nagaveni, NB | 1 |
| Pathak, S | 1 |
| Poornima, P | 1 |
| Joshi, JS | 1 |
| Nakornchai, S | 1 |
| Banditsing, P | 1 |
| Visetratana, N | 1 |
| Kargül, B | 1 |
| Tanboga, I | 1 |
| Altinok, B | 1 |
| Rockenbach, MI | 1 |
| Gomes-Filho, JE | 1 |
| Duarte, PC | 1 |
| de Oliveira, CB | 1 |
| Watanabe, S | 1 |
| Lodi, CS | 1 |
| Cintra, LT | 1 |
| Bernabé, PF | 1 |
| Jung, IY | 1 |
| Lee, SJ | 1 |
| Hargreaves, KM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Comparative Clinical and Radiographic Study of 3Mixstatin vs Tri-Antibiotic Mix and Simvastatin in the Treatment of Primary Molars With Inflammatory Root Resorption A Randomized Clinical Trial[NCT03585751] | 45 participants (Anticipated) | Interventional | 2018-09-30 | Not yet recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for metronidazole and Teeth, Devitalized
| Article | Year |
|---|---|
Clinical evaluation of 3Mix and Vitapex as treatment options for pulpally involved primary molars.
Topics: Anti-Bacterial Agents; Calcium Hydroxide; Child; Child, Preschool; Ciprofloxacin; Dental Pulp Necros | 2010 |
8 other studies available for metronidazole and Teeth, Devitalized
| Article | Year |
|---|---|
Intracanal delivery of Resolvin E1 controls inflammation in necrotic immature rat teeth.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Ciprofloxacin; Dental Pulp Cavity; Dental | 2014 |
Long-term follow up of revascularization using platelet-rich fibrin.
Topics: Anti-Bacterial Agents; Apexification; Blood Platelets; Child; Ciprofloxacin; Dental Papilla; Dental | 2016 |
Revascularization Induced Maturogenesis of Non-Vital Immature Permanent Tooth Using Platelet-Rich-Fibrin: A Case Report.
Topics: Anti-Bacterial Agents; Apexification; Blood Platelets; Child; Ciprofloxacin; Dental Pulp Cavity; Den | 2016 |
Conventional endodontic treatment of primary molars using metronidazole as an intra-canal medicament: a pilot study.
Topics: Abscess; Alveolar Bone Loss; Anti-Infective Agents; Child; Dental Fistula; Dental Pulp Diseases; Fem | 2010 |
Response to intracanal medication in immature teeth with pulp necrosis: an experimental model in rat molars.
Topics: Animals; Anti-Bacterial Agents; Apexification; Cementogenesis; Ciprofloxacin; Dental Pulp Necrosis; | 2011 |
Tissue reaction to a triantibiotic paste used for endodontic tissue self-regeneration of nonvital immature permanent teeth.
Topics: Animals; Anti-Bacterial Agents; Apexification; Biocompatible Materials; Calcinosis; Calcium Hydroxid | 2012 |
Apical periodontium response to enamel matrix derivative as an intracanal medication in rat immature teeth with pulp necrosis: radiographic and histologic findings.
Topics: Animals; Anti-Bacterial Agents; Cementogenesis; Ciprofloxacin; Dental Cementum; Dental Enamel Protei | 2012 |
Biologically based treatment of immature permanent teeth with pulpal necrosis: a case series.
Topics: Adolescent; Aluminum Compounds; Anti-Bacterial Agents; Apexification; Calcium Compounds; Calcium Hyd | 2012 |