metronidazole has been researched along with Taste Disorder, Anterior Tongue in 9 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We examined the therapeutic effects of albendazole compared to metronidazole in 120 patients with giardiasis in Hamdan." | 9.12 | Albendazole versus metronidazole in the treatment of patients with giardiasis in the Islamic Republic of Iran. ( Alizadeh, A; Bodaghi, M; Kashani, KM; Ranjbar, M; Taheri, MM, 2006) |
| "We examined the therapeutic effects of albendazole compared to metronidazole in 120 patients with giardiasis in Hamdan." | 5.12 | Albendazole versus metronidazole in the treatment of patients with giardiasis in the Islamic Republic of Iran. ( Alizadeh, A; Bodaghi, M; Kashani, KM; Ranjbar, M; Taheri, MM, 2006) |
| "Patients with active HP infection and peptic ulcer, a history of peptic ulcer, or nonulcer dyspepsia were randomized to either lansoprazole 30 mg b." | 5.08 | Bismuth subsalicylate instead of metronidazole with lansoprazole and clarithromycin for Helicobacter pylori infection: a randomized trial. ( Barnett, JL; Chey, WD; DelValle, J; Elta, GH; Fisher, L; Hasler, WL; Nostrant, T; Scheiman, JM, 1997) |
| " pylori-positive peptic ulcer received omeprazole 20 mg twice daily in combination with metronidazole 400 mg twice daily and clarithromycin 500 mg twice daily for seven days." | 5.08 | One week triple therapy for Helicobacter pylori: does high-dose clarithromycin confer additional benefit? ( Bhutta, AS; Bindel, H; Cunnane, K; Loane, J; O'Connor, HJ, 1997) |
| " pylori-positive peptic ulcer received lansoprazole 30 mg twice daily in combination with metronidazole 400 mg twice daily and clarithromycin 250 mg twice daily for 5 days." | 5.08 | Lansoprazole triple therapy for Helicobacter pylori--is 5 days enough? ( Cunnane, K; Kelly, S; Laundon, J; McLoughlin, R; O'Connor, HJ, 1998) |
| " The incidence of adverse effects was significantly lower in the group given satranidazole (P < ." | 2.72 | Randomized, single-blind, placebo-controlled multicenter trial to compare the efficacy and safety of metronidazole and satranidazole in patients with amebic liver abscess. ( Kar, P; Madan, K; Muzaffar, J; Sharma, MP, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moraes, ME | 1 |
| Cunha, GH | 1 |
| Bezerra, MM | 1 |
| Fechine, FV | 1 |
| Pontes, AV | 1 |
| Andrade, WS | 1 |
| Frota Bezerra, FA | 1 |
| Moraes, MO | 1 |
| Cavalcanti, PP | 1 |
| Sancar, M | 1 |
| Izzettin, FV | 1 |
| Apikoglu-Rabus, S | 1 |
| Besisik, F | 1 |
| Tozun, N | 1 |
| Dulger, G | 1 |
| Muzaffar, J | 1 |
| Madan, K | 1 |
| Sharma, MP | 1 |
| Kar, P | 1 |
| Alizadeh, A | 1 |
| Ranjbar, M | 1 |
| Kashani, KM | 1 |
| Taheri, MM | 1 |
| Bodaghi, M | 1 |
| Chey, WD | 1 |
| Fisher, L | 1 |
| Elta, GH | 1 |
| Barnett, JL | 1 |
| Nostrant, T | 1 |
| DelValle, J | 1 |
| Hasler, WL | 1 |
| Scheiman, JM | 1 |
| Schwartz, H | 1 |
| Krause, R | 1 |
| Siepman, N | 1 |
| Haber, M | 1 |
| Weissfeld, A | 1 |
| Kidd, S | 1 |
| Rose, P | 1 |
| Sahba, B | 1 |
| O'Connor, HJ | 2 |
| Loane, J | 1 |
| Bindel, H | 1 |
| Bhutta, AS | 1 |
| Cunnane, K | 2 |
| McLoughlin, R | 1 |
| Kelly, S | 1 |
| Laundon, J | 1 |
| Griffin, JP | 1 |
1 review available for metronidazole and Taste Disorder, Anterior Tongue
| Article | Year |
|---|---|
Drug-induced disorders of taste.
Topics: Adverse Drug Reaction Reporting Systems; Captopril; Humans; Metronidazole; Mouth Neoplasms; Penicill | 1992 |
8 trials available for metronidazole and Taste Disorder, Anterior Tongue
| Article | Year |
|---|---|
Efficacy of the Mentha crispa in the treatment of women with Trichomonas vaginalis infection.
Topics: Adult; Antitrichomonal Agents; Double-Blind Method; Dyspareunia; Dysuria; Female; Humans; Male; Ment | 2012 |
Pharmacoeconomic comparison of Helicobacter pylori eradication regimens.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Amoxicillin; Anti-Infective Agents; Clar | 2006 |
Randomized, single-blind, placebo-controlled multicenter trial to compare the efficacy and safety of metronidazole and satranidazole in patients with amebic liver abscess.
Topics: Adult; Antiprotozoal Agents; Drug Tolerance; Female; Humans; Incidence; Liver Abscess, Amebic; Male; | 2006 |
Albendazole versus metronidazole in the treatment of patients with giardiasis in the Islamic Republic of Iran.
Topics: Adolescent; Adult; Albendazole; Anorexia; Antiprotozoal Agents; Child; Child, Preschool; Drug Admini | 2006 |
Bismuth subsalicylate instead of metronidazole with lansoprazole and clarithromycin for Helicobacter pylori infection: a randomized trial.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Abdominal Pain; Anti-Bacterial Agents; Anti-Ulcer Agents; B | 1997 |
Seven-day triple therapy with lansoprazole, clarithromycin, and metronidazole for the cure of Helicobacter pylori infection: a short report.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Clarithromycin; Diarrhea; Drug Administration | 1996 |
One week triple therapy for Helicobacter pylori: does high-dose clarithromycin confer additional benefit?
Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Anti-Ulcer Agents; Antitrichomonal Agents; Cl | 1997 |
Lansoprazole triple therapy for Helicobacter pylori--is 5 days enough?
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Bacterial | 1998 |