metronidazole has been researched along with Swine Diseases in 2 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Swine Diseases: Diseases of domestic swine and of the wild boar of the genus Sus.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In 1977 swine dysentery was made a notifiable disease in the German Democratic Republic, with the intention of eradicating it by the systematic treatment of clinically affected herds using intensive medication and hygiene control programmes." | 5.27 | Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme. ( Blaha, T; Burch, DG; Erler, W, 1987) |
| "In 1977 swine dysentery was made a notifiable disease in the German Democratic Republic, with the intention of eradicating it by the systematic treatment of clinically affected herds using intensive medication and hygiene control programmes." | 1.27 | Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme. ( Blaha, T; Burch, DG; Erler, W, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blaha, T | 1 |
| Erler, W | 1 |
| Burch, DG | 1 |
| Schulze, F | 1 |
| Kielstein, P | 1 |
2 other studies available for metronidazole and Swine Diseases
| Article | Year |
|---|---|
Swine dysentery control in the German Democratic Republic and the suitability of injections of tiamulin for the programme.
Topics: Animals; Anti-Bacterial Agents; Diterpenes; Dysentery; Female; Follow-Up Studies; Germany, East; Leu | 1987 |
[Effect of metronidazole on the gastrointestinal flora of swine].
Topics: Animals; Bacteria; Digestive System; Dysentery; Metronidazole; Swine; Swine Diseases | 1987 |