metronidazole has been researched along with Spondylitis in 5 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Spondylitis: Inflammation of the SPINE. This includes both arthritic and non-arthritic conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metronidazole is an antimicrobial agent commonly used in the treatment of several protozoal and anaerobic infections." | 5.48 | Metronidazole-induced encephalopathy in a patient with pyogenic spondylitis: a case report. ( Kobatake, T; Mawatari, M; Mizuta, K; Morimoto, T; Nakayama, D; Nozaki, O; Sonohata, M, 2018) |
| " Lumbar spinal magnetic resonance imaging (MRI) revealed infective spondylitis, and metronidazole (1." | 4.31 | Metronidazole-induced encephalopathy delayed diagnosis due to cerebellar infarction: A case report. ( Cha, S; Cho, KH; Lee, BC; Moon, CW, 2023) |
| "Metronidazole was the most common antibiotic used for treatment (eight patients), either as monotherapy or in combination with other antibiotics." | 2.44 | Bacteroides fragilis vertebral osteomyelitis: case report and a review of the literature. ( Elgouhari, H; Gerstein, WH; Othman, M, 2007) |
| "Metronidazole is an antimicrobial agent commonly used in the treatment of several protozoal and anaerobic infections." | 1.48 | Metronidazole-induced encephalopathy in a patient with pyogenic spondylitis: a case report. ( Kobatake, T; Mawatari, M; Mizuta, K; Morimoto, T; Nakayama, D; Nozaki, O; Sonohata, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cha, S | 1 |
| Lee, BC | 1 |
| Moon, CW | 1 |
| Cho, KH | 1 |
| Mizuta, K | 1 |
| Sonohata, M | 1 |
| Nozaki, O | 1 |
| Kobatake, T | 1 |
| Nakayama, D | 1 |
| Morimoto, T | 1 |
| Mawatari, M | 1 |
| Englert, C | 1 |
| Aebert, H | 1 |
| Lenhart, M | 1 |
| Solleder, A | 1 |
| Nerlich, M | 1 |
| Neumann, C | 1 |
| Elgouhari, H | 1 |
| Othman, M | 1 |
| Gerstein, WH | 1 |
| Fabie, F | 1 |
| Arrue, P | 1 |
| Thorn-Kany, M | 1 |
| Toulemonde, A | 1 |
| Vally, P | 1 |
| Lagarrigue, J | 1 |
2 reviews available for metronidazole and Spondylitis
| Article | Year |
|---|---|
Bacteroides fragilis vertebral osteomyelitis: case report and a review of the literature.
Topics: Anti-Infective Agents; Bacteroides fragilis; Bacteroides Infections; Humans; Lumbar Vertebrae; Male; | 2007 |
[Cervical spine infection with Streptococcus anginosus. Case report].
Topics: Adult; Ampicillin; Cervical Vertebrae; Drug Therapy, Combination; Humans; Magnetic Resonance Imaging | 1999 |
3 other studies available for metronidazole and Spondylitis
| Article | Year |
|---|---|
Metronidazole-induced encephalopathy delayed diagnosis due to cerebellar infarction: A case report.
Topics: Aged; Anti-Bacterial Agents; Brain Diseases; Brain Ischemia; Cerebellar Diseases; Delayed Diagnosis; | 2023 |
Metronidazole-induced encephalopathy in a patient with pyogenic spondylitis: a case report.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Diffusion Magnetic Resonance Imaging; Female; Gram-Positiv | 2018 |
Thoracic spondylitis from a mycotic (Streptococcus pneumoniae) aortic aneurysm: a case report.
Topics: Aneurysm, Infected; Anti-Bacterial Agents; Aortic Aneurysm, Thoracic; Blood Vessel Prosthesis Implan | 2004 |