metronidazole has been researched along with Sore Throat in 12 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The potential role of anaerobic bacteria in acute tonsillitis was investigated in a retrospective study that evaluated the efficacy of antimicrobial therapy with metronidazole on the management of acute episodes of non-beta-hemolytic streptococcal tonsillitis (NST)." | 7.73 | Treatment of non-streptococcal tonsillitis with metronidazole. ( Brook, I; Gober, AE, 2005) |
| "The potential role of anaerobic bacteria in acute tonsillitis was investigated in a retrospective study that evaluated the efficacy of antimicrobial therapy with metronidazole on the management of acute episodes of non-beta-hemolytic streptococcal tonsillitis (NST)." | 3.73 | Treatment of non-streptococcal tonsillitis with metronidazole. ( Brook, I; Gober, AE, 2005) |
| "An increasingly reported entity, Lemierre's syndrome classically presents with a recent oropharyngeal infection, internal jugular vein thrombosis and the presence of anaerobic organisms such as Fusobacterium necrophorum." | 1.42 | Clival osteomyelitis and hypoglossal nerve palsy--rare complications of Lemierre's syndrome. ( Adlan, T; He, J; Lam, JC, 2015) |
| "Lemierre's syndrome is a rare yet potentially fatal cause of sore throat." | 1.39 | Doctor, I have a sore throat. ( Dholakia, S; Hashimi, Y, 2013) |
| "Lemierre syndrome is a disease that every pediatrician must know." | 1.35 | [Lemierre syndrome: a complication of an oropharyngeal infection]. ( Bailly, C; Berlioz, M; Boutté, P; Passalidou, P, 2008) |
| "Lemierre's syndrome is a rare but potentially life-threatening entity that follows an oropharyngeal infection." | 1.32 | A case of Lemierre's syndrome. ( Jauch, EC; Johnson, MC; Ma, M, 2003) |
| "Circumscribed osteitis of a child's mandibula, with no dental etiology occurs around 7-years of age, adjacent to a healthy first molar." | 1.30 | [Circumscribed mandibular osteitis in children due to hematogenous dissemination. Apropos of 5 clinical cases]. ( Buis, J; Diner, PA; Franchi, G; Karcenty, B; Soupre, V; Vazquez, MP, 1999) |
| "Necrobacillosis is a potentially life-threatening septicaemic illness occurring in the previously fit and healthy." | 1.29 | Necrobacillosis--an unusual case of pharyngotonsillitis. ( Carrie, S; Fenton, PA, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (8.33) | 18.7374 |
| 1990's | 4 (33.33) | 18.2507 |
| 2000's | 5 (41.67) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| He, J | 1 |
| Lam, JC | 1 |
| Adlan, T | 1 |
| Passalidou, P | 1 |
| Berlioz, M | 1 |
| Bailly, C | 1 |
| Boutté, P | 1 |
| Dholakia, S | 1 |
| Hashimi, Y | 1 |
| Zätterstrøm, UK | 1 |
| Hokland, BM | 1 |
| Walberg, M | 1 |
| Stubhaug, A | 1 |
| Aaløkken, TM | 1 |
| Frøland, SS | 1 |
| Ma, M | 1 |
| Jauch, EC | 1 |
| Johnson, MC | 1 |
| Spitzer, C | 1 |
| Foltys, H | 1 |
| Lemmen, SW | 1 |
| Block, F | 1 |
| Brook, I | 1 |
| Gober, AE | 1 |
| Carrie, S | 1 |
| Fenton, PA | 1 |
| Carlson, ER | 1 |
| Bergamo, DF | 1 |
| Coccia, CT | 1 |
| Bouton, F | 1 |
| Cotils, M | 1 |
| Genard, M | 1 |
| Hubert, C | 1 |
| Franchi, G | 1 |
| Soupre, V | 1 |
| Karcenty, B | 1 |
| Buis, J | 1 |
| Diner, PA | 1 |
| Vazquez, MP | 1 |
| O'Grady, FW | 1 |
| Lambert, HP | 1 |
| Begent, RH | 1 |
2 reviews available for metronidazole and Sore Throat
| Article | Year |
|---|---|
[Bacterial meningitis as a complication of Fusobacterium necroforum infection in adults].
Topics: Adult; Anti-Bacterial Agents; Blood Glucose; Cerebrospinal Fluid Proteins; Diagnosis, Differential; | 2003 |
[Septic thrombophlebitis of the internal jugular vein and Lemierre syndrome].
Topics: Abscess; Acute Disease; Aged; Amoxicillin-Potassium Clavulanate Combination; Angina Pectoris; Anti-B | 1998 |
10 other studies available for metronidazole and Sore Throat
| Article | Year |
|---|---|
Clival osteomyelitis and hypoglossal nerve palsy--rare complications of Lemierre's syndrome.
Topics: Adolescent; Anti-Infective Agents; Anticoagulants; Cranial Fossa, Posterior; Fever; Fusobacterium In | 2015 |
[Lemierre syndrome: a complication of an oropharyngeal infection].
Topics: Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Anti-Infective Agents; Cefotax | 2008 |
Doctor, I have a sore throat.
Topics: Aged, 80 and over; Anti-Bacterial Agents; Diagnosis, Differential; Humans; Jugular Veins; Lemierre S | 2013 |
[A throat infection with rapid deterioration].
Topics: Abscess; Anti-Bacterial Agents; Diagnosis, Differential; Disease Progression; Drug Therapy, Combinat | 2002 |
A case of Lemierre's syndrome.
Topics: Adolescent; Anti-Bacterial Agents; Clindamycin; Drug Therapy, Combination; Female; Fusobacterium Inf | 2003 |
Treatment of non-streptococcal tonsillitis with metronidazole.
Topics: Adolescent; Anti-Infective Agents; Bacteria, Anaerobic; Child; Female; Fever; Humans; Lymphadenitis; | 2005 |
Necrobacillosis--an unusual case of pharyngotonsillitis.
Topics: Adult; Drug Therapy, Combination; Fusobacterium Infections; Fusobacterium necrophorum; Humans; Kidne | 1994 |
Lemierre's syndrome: two cases of a forgotten disease.
Topics: Adolescent; Arthritis, Infectious; Bacteremia; Cefoxitin; Clindamycin; Fusobacterium Infections; Fus | 1994 |
[Circumscribed mandibular osteitis in children due to hematogenous dissemination. Apropos of 5 clinical cases].
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Infective Agents; Bacteremia; Child; Curettage; Focal Infec | 1999 |
Sensible prescribing. III. Acute otitis media and sore throat.
Topics: Amphotericin B; Ampicillin; Anti-Bacterial Agents; Aspirin; Cephalexin; Drug Prescriptions; Erythrom | 1975 |