metronidazole has been researched along with Skin Diseases, Infectious in 10 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Skin Diseases, Infectious: Skin diseases caused by bacteria, fungi, parasites, or viruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metronidazole also has been used either alone or in combination, most frequently with amoxicillin, to treat many other anaerobic infections: head and neck, pleuropulmonary, genital tract, bone and joint, skin and soft tissue, and cases of fusobacterial septicemia (necrobacillosis)." | 1.27 | The therapeutic use of metronidazole in anaerobic infection: six years' experience in a London hospital. ( Eykyn, SJ, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Little, K | 1 |
| Eykyn, SJ | 1 |
| Adams, EB | 1 |
| MacLeod, IN | 1 |
| Beaune, J | 1 |
| Llorca, G | 1 |
| Gonin, A | 1 |
| Brun, Y | 1 |
| Fleurette, J | 1 |
| Neidhart, JP | 1 |
| Sunarwan, I | 1 |
| Jones, BM | 1 |
| Geary, I | 1 |
| Lee, ME | 1 |
| Duerden, BI | 1 |
| Cockerill, FR | 1 |
| Rosenblatt, JE | 1 |
| Lee, DT | 1 |
| Gay, JD | 1 |
| Feingold, DS | 1 |
| Wagner, RF | 1 |
| Reznikov, M | 1 |
| Hakendorf, PH | 1 |
| Matthews, DB | 1 |
| Müller, E | 1 |
| Sturm, G | 1 |
1 review available for metronidazole and Skin Diseases, Infectious
| Article | Year |
|---|---|
Antibacterial therapy.
Topics: Anti-Bacterial Agents; Anti-Infective Agents, Local; Cephalosporins; Clindamycin; Drug Combinations; | 1986 |
9 other studies available for metronidazole and Skin Diseases, Infectious
| Article | Year |
|---|---|
What is causing this patient's multiple skin abscesses?
Topics: Abscess; Adolescent; Colitis, Ulcerative; Cyclosporine; Dermatologic Agents; Female; Gastrointestina | 2018 |
The therapeutic use of metronidazole in anaerobic infection: six years' experience in a London hospital.
Topics: Adult; Aged; Bacterial Infections; Bone Diseases; Empyema; Female; Fusobacterium Infections; Gastroi | 1983 |
Invasive amebiasis. I. Amebic dysentery and its complications.
Topics: Adult; Amebiasis; Amebicides; Child, Preschool; Colonic Diseases; Entamoeba histolytica; Granuloma; | 1977 |
[Necrotic phlegmon of the hand, starting point for a septicemia caused by Aeromonas hydrophila. Demonstration of the ichthyological origin of the infection].
Topics: Aeromonas; Animals; Bacterial Infections; Cellulitis; Chloramphenicol; Doxycycline; Drug Therapy, Co | 1978 |
A case of cutaneous amoebiasis.
Topics: Acetanilides; Amebiasis; Amebicides; Colostomy; Entamoebiasis; Furans; Humans; Male; Metronidazole; | 1975 |
Comparison of the in vitro activities of fenticonazole, other imidazoles, metronidazole, and tetracycline against organisms associated with bacterial vaginosis and skin infections.
Topics: Antifungal Agents; Bacteria; Female; Humans; Imidazoles; Metronidazole; Microbial Sensitivity Tests; | 1989 |
Comparison of clindamycin, metronidazole, and penicillin for the treatment of experimental infections in mice caused by beta-lactamase-producing Bacteroides intermedius.
Topics: Abscess; Animals; Bacteroides; Bacteroides Infections; beta-Lactamases; Clindamycin; Male; Metronida | 1986 |
Response of a 'susceptible' Escherichia coli to metronidazole therapy: an investigation using experimental subcutaneous abscesses.
Topics: Abscess; Animals; Bacteroides fragilis; Bacteroides Infections; Drug Resistance, Microbial; Escheric | 1985 |
[Protozoan infections of the skin].
Topics: Amphotericin B; Antimony; Female; Germany, West; Humans; Leishmania; Leishmaniasis, Mucocutaneous; M | 1974 |