metronidazole has been researched along with Skin Diseases, Bacterial in 6 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Skin Diseases, Bacterial: Skin diseases caused by bacteria.
| Excerpt | Relevance | Reference |
|---|---|---|
| "pylori infection." | 2.39 | May Helicobacter pylori be important for dermatologists? ( Drago, F; Parodi, A; Rebora, A, 1995) |
| " This case presents diagnosis and treatment of SIRS with staphylococcal skin infection in a dog that was immunosuppressed due to long-term use of corticosteroid." | 1.40 | Staphylococcus pseudintermedius infection associated with nodular skin lesions and systemic inflammatory response syndrome in a dog. ( Kang, MH; Min, SH; Park, HM; Sur, JH, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Amsler, KM | 1 |
| Davies, TA | 1 |
| Shang, W | 1 |
| Jacobs, MR | 1 |
| Bush, K | 1 |
| Min, SH | 1 |
| Kang, MH | 1 |
| Sur, JH | 1 |
| Park, HM | 1 |
| Løes, S | 1 |
| Lekven, N | 1 |
| Rebora, A | 1 |
| Drago, F | 1 |
| Parodi, A | 1 |
| Semret, M | 1 |
| Koromihis, G | 1 |
| MacLean, JD | 1 |
| Libman, M | 1 |
| Ward, BJ | 1 |
| Wedi, B | 1 |
| Kapp, A | 1 |
2 reviews available for metronidazole and Skin Diseases, Bacterial
| Article | Year |
|---|---|
May Helicobacter pylori be important for dermatologists?
Topics: Bacterial Toxins; Case-Control Studies; Chronic Disease; Gastric Mucosa; Helicobacter Infections; He | 1995 |
Helicobacter pylori infection in skin diseases: a critical appraisal.
Topics: Amoxicillin; Clarithromycin; Clinical Trials as Topic; Comorbidity; Drug Therapy, Combination; Femal | 2002 |
1 trial available for metronidazole and Skin Diseases, Bacterial
| Article | Year |
|---|---|
In vitro activity of ceftobiprole against pathogens from two phase 3 clinical trials of complicated skin and skin structure infections.
Topics: Anti-Bacterial Agents; Cephalosporins; Enterobacteriaceae; Gram-Negative Bacteria; Gram-Negative Bac | 2008 |
3 other studies available for metronidazole and Skin Diseases, Bacterial
| Article | Year |
|---|---|
Staphylococcus pseudintermedius infection associated with nodular skin lesions and systemic inflammatory response syndrome in a dog.
Topics: Animals; Anti-Bacterial Agents; Cefotaxime; Dog Diseases; Dogs; Female; Metronidazole; Skin Diseases | 2014 |
Temporal abscess after tooth extractions.
Topics: Abscess; Adult; C-Reactive Protein; Drainage; Drug Therapy, Combination; Follow-Up Studies; Humans; | 2010 |
Mycobacterium ulcerans infection (Buruli ulcer): first reported case in a traveler.
Topics: Adult; Africa; Anti-Bacterial Agents; Antibiotics, Antitubercular; Antitubercular Agents; Ciprofloxa | 1999 |