metronidazole has been researched along with Salmonella Infections, Animal in 1 studies
Metronidazole: A nitroimidazole used to treat AMEBIASIS; VAGINITIS; TRICHOMONAS INFECTIONS; GIARDIASIS; ANAEROBIC BACTERIA; and TREPONEMAL INFECTIONS.
metronidazole : A member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death.
Salmonella Infections, Animal: Infections in animals with bacteria of the genus SALMONELLA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although all antibiotic treatments caused similar increases in pathogen colonization, the development of enterocolitis was seen only when streptomycin or vancomycin was used; no significant pathology was observed with the use of metronidazole." | 3.77 | The intestinal microbiota plays a role in Salmonella-induced colitis independent of pathogen colonization. ( Antunes, LC; Croxen, MA; Ferreira, RB; Finlay, BB; Gill, N; Russell, SL; Willing, BP, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ferreira, RB | 1 |
| Gill, N | 1 |
| Willing, BP | 1 |
| Antunes, LC | 1 |
| Russell, SL | 1 |
| Croxen, MA | 1 |
| Finlay, BB | 1 |
1 other study available for metronidazole and Salmonella Infections, Animal
| Article | Year |
|---|---|
The intestinal microbiota plays a role in Salmonella-induced colitis independent of pathogen colonization.
Topics: Animals; Anti-Infective Agents; Bacteria; Cation Transport Proteins; Ecosystem; Enterocolitis; Feces | 2011 |